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FOSB Gene

protein-coding GIFtS: 63

GC19P050663

FBJ murine osteosarcoma viral oncogene homolog B
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
AP-1 ^¹, ²
DKFZp686C0818 ^¹, ²
G0S3 ^¹, ², ³
GOS3 ^¹, ²
GOSB ^¹, ²
MGC42291 ^¹, ²

Descriptions
FBJ murine osteosarcoma viral oncogene homolog B ^²
G0/G1 switch regulatory protein 3 ^³
activator protein 1 ^²
oncogene FOS-B ^²

External Ids
HGNC: 3797¹
Entrez Gene: 2354²
UniProtKB: P53539³
Ensembl: ENSG00000125740⁷

Search outside databases for aliases for FOSB gene

Previous GC identifers: GC19P046615 GC19P046362 GC19P050647

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for FOSB:

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine

zipper proteins that can dimerize with proteins of the JUN family, thereby forming the

transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of

cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants

encoding different isoforms have been found for this gene. [provided by RefSeq]

UniProtKB/Swiss-Prot: FOSB_HUMAN, P53539

Function: FosB interacts with Jun proteins enhancing their DNA binding activity

Gene Wiki entry for FOSB

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the FOSB gene

Entrez Gene cytogenetic band: 19q13.32 Ensembl cytogenetic band: 19q13.32 HGNC cytogenetic band: 19q13.3

FOSB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19P050663: (about GC identifiers)

Start:	50,663,093 bp from pter
End:	50,670,276 bp from pter
Size:	7,184 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000019.8 NT_011109.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: FOSB_HUMAN, P53539 (See protein sequence)

Recommended Name: Protein fosB

Size: 338 amino acids; 35928 Da

Subunit: Heterodimer (By similarity)

Subcellular location: Nucleus

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (2 alternative transcripts):

NP_001107643.1 NP_006723.2

ENSEMBL proteins:

ENSP00000245919

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Fos B)
	Human Recombinant Proteins from Abnova (FOSB)

OriGene Purified Recombinant Human Protein: FOSB

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--

About this table

Antibodies for FOSB:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for FOSB
	R&D Systems Antibodies for FOSB (FosB/G0S3)
	Cell Signaling Technology (CST) Antibodies for FOSB
	Antibodies from Abcam (Fos B), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (FOSB)
	Novus Biologicals Antibodies for FOSB

Assays for FOSB:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P53539

ProtoNet protein and cluster: P53539

1 Blocks protein family: IPB000837 Fos transforming protein signature

UniProtKB/Swiss-Prot: FOSB_HUMAN, P53539

Similarity: Belongs to the bZIP family. Fos subfamily

Similarity: Contains 1 bZIP domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (FOSB)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (FOSB)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_006732

Applied Biosystems Silencer® siRNAs for FOSB

Sigma-Aldrich siRNA for FOSB

Sigma-Aldrich shRNA for FOSB

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for FOSB
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001114171
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001114171
untagged cDNA clones in CMV expression vector (see all 2): NM_001114171

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_006732

UniProtKB/Swiss-Prot: FOSB_HUMAN, P53539

Function: FosB interacts with Jun proteins enhancing their DNA binding activity

Genatlas biochemistry entry for FOSB:

murine FBJ osteosarcoma viral (v-fos) oncogen homolog B,ligand induced,immediate (primary) early

response gene

3 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Fosb):

behavior/neurological

growth/size

nervous system

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003700	transcription factor activity	IEA	--
GO:0008134	transcription factor binding	TAS	1900040
GO:0043565	sequence-specific DNA binding	IEA	--
GO:0046983	protein dimerization activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

1 Sigma-Aldrich "Your Favorite Gene" Pathway for FOSB (Your Favorite Gene powered by Ingenuity)

CDK5 Signaling

GeneDecks FOSB for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for FOSB

5/16 Interacting proteins for FOSB (ENSP00000245919³) via UniProtKB, MINT, and/or STRING (see all 16 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
JUND	ENSP00000252818³	STRING (score=.973)
BCS1L	ENSP00000352219³	STRING (score=.91)
DKK1	ENSP00000363081³	STRING (score=.899)
EGR1	ENSP00000239938³	STRING (score=.881)
CCND1	ENSP00000227507³	STRING (score=.862)

About this table

4 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	TAS	1900040
GO:0006355	regulation of transcription, DNA-dependent	IEA	--
GO:0007275	multicellular organismal development	TAS	8706134
GO:0007610	behavior	TAS	8706134

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for FOSB
8 Novoseek chemical compound relationships for FOSB gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
12-o-tetradecanoylphorbol 13-acetate	40.67	2	11751871 (1), 7931079 (1)
leucine	36.19	2	7919342 (1), 15828020 (1)
okadaic acid	35.85	6	9873060 (4), 8706012 (1)
phorbol	32.29	1	7671329 (1)
oligonucleotide	22.09	1	11751871 (1)
matrigel	21.48	1	15319566 (1)
calcium	0.00	1	9523591 (1)
tyrosine	0.00	2	7671329 (2)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (FOSB)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (FOSB)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_006732

Sigma-Aldrich siRNA for FOSB

Sigma-Aldrich shRNA for FOSB

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001114171 NM_006732

REFSEQ mRNAs for FOSB gene (2 alternative transcripts):

NM_001114171.1 NM_006732.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001114171 NM_006732

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001114171
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001114171
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_001114171

Additional cDNA sequence:

AF432216.1 AK097324.1 AK225070.1 AK292720.1 BC036724.1 BC040197.1 BC051767.1 BC063042.1

BC127825.1 BX538117.1 CR542101.1 D16366.1 EU178109.1 EU178110.1 EU178111.1 EU178112.1

EU178113.1 EU178114.1 EU178115.1 EU178116.1 L49169.1

23 DOTS entries:

DT.91704152 DT.99937901 DT.40245732 DT.448257 DT.97769742 DT.100738687 DT.121483522 DT.92461989

DT.91698465 DT.100783281 DT.121483409 DT.92461968 DT.121483503 DT.97766554 DT.121483419 DT.121483506

DT.91659175 DT.92026343 DT.92461994 DT.95254289 DT.95168169 DT.95168170 DT.97814403

24/327 AceView cDNA sequences (see all 327 ):

CA848309 CA312265 CA775066 F02073 BG150133 BQ876665 BX538117 AU141406

BF854518 BF109779 BF055464 BQ182879 AV719542 CN483447 BQ181364 AU141819

AI744962 F05827 BU146670 AV645429 AA019321 AA664063 AA296039 AJ346436

highest scoring ESTs for FOSB:

L49169 AA019321 AA034135 AA235570 AA235696 AA292468 AA296039 AA296040 AA397702 AA399045

Unigene Cluster for FOSB:

FBJ murine osteosarcoma viral oncogene homolog B

Hs.590958 [show with all ESTs]

Unigene Representative Sequence: BC036724

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for FOSB

ExUns:	1a	·	1b	^	2	^	3a	·	3b	^	4a	·	4b	^	5	^	6
SP1:					-		-				-
SP2:											-
SP3:					-		-				-		-
SP4:							-				-
SP5:

About this scheme

ECgene alternative splicing isoforms for FOSB

1 Ensembl transcript including schematic representation:

ENST00000353609

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

FOSB expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for FOSB

¹ / ² / ³

3 probe-sets matching FOSB gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
36669_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	L49169	1.00	1.00	1.00	1
202768_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_006732	0.60	1.00	0.82	1
202768_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: CTGTACTTGT

SOURCE GeneReport for Unigene cluster: Hs.590958
Expression variation in blood from EXPOLDB for FOSB

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for FOSB gene from 5 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	FOSB¹	--	FBJ murine osteosarcoma viral oncogene homolog B	94.56(n) 97.63(a)	484445 XM_850519.1 XP_855612.1
chimpanzee (Pan troglodytes)	FOSB¹	--	FBJ murine osteosarcoma viral oncogene homolog B	99.9(n) 100(a)	456127 XM_512748.2 XP_512748.2
rat (Rattus norvegicus)	Fosb¹	--	FBJ osteosarcoma oncogene B	90.21(n) 95.25(a)	308411 XM_001057199.1 XP_001057199.1
mouse (Mus musculus)	Fosb^{1, 5}	7 (5.00 cM)⁵	FBJ osteosarcoma oncogene B^{1, 5}	90.6(n)¹ 95.85(a)¹	14282¹ NM_008036.2¹ NP_032062.1¹ AF093624⁵ AI846927⁵ (see all 13)
zebrafish (Danio rerio)	zgc:92354¹	--	zgc:92354	67.25(n) 74.42(a)	492346 NM_001007312.1 NP_001007313.1

About this table Species with no ortholog for FOSB

ENSEMBL Gene Tree for FOSB

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for FOSB gene

FOSL1² FOSL2² FOS²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/86 NCBI SNPs in FOSB are shown (see all 86 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 58)

AB	SNP ID	Valid	Chr 19 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs1049739^1,2	A,C,F,H	50670215(+)	`TTGGCA/GATGGG`	2	--	ut3¹ ese³		14		EA MN NA EU NS	2265
	rs708905^1,2	A,C,F,H	50669312(+)	`GAAGGG/CAGTGA`	2	--	ut3¹ trp³		13		NA EA MN EU WA NS	1034
	rs12373539^1,2	A,C,F,H	50662935(+)	`TGCAAG/ATGACC`	1	--	ng5¹		9		NS EU EA WA	596
--	rs10424098^1,2	C,F	50668476(+)	`AGGATG/TAAGGG`	2	--	ut3¹		5		NS	190
--	rs8106229^1,2	A,C	50670530(+)	`GTAAGG/TGGCTA`	1	--	ng3¹		0	--	--	--	--
--	rs11351764^1,2	C,F	50668694(+)	`CCCCC-/CTTAAA`	2	--	ut3¹ trp³		5		NS	188
	rs1049698^1,2	C,F	50668598(+)	`GTGCCT/CAGGTT`	2	--	ut3¹ ese³		6		MN NS	372
--	rs10422572^1,2	C,F	50668599(+)	`TGCCTA/TGGTTG`	2	--	ut3¹ ese³		5		NS	188
--	rs3170167^1,2	C,F	50668558(+)	`CTCCCT/CACCCA`	2	--	ut3¹		6		MN NS	372
	rs10409841^1,2	C,H	50661494(+)	`AGGAGT/ATTGTA`	1	--	ng5¹ trp³		9		EU EA WA NS	578

About this table

HapMap Linkage Disequilibrium images for FOSB (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 164772

5 Novoseek disease relationships for FOSB gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
nsclc	1.49	1	9662339 (1)
tumors	1.19	11	10502734 (4), 15514944 (1), 9528756 (1), 10918184 (1) (see all 5)
necrosis	0.00	1	9528756 (1)
carcinoma	0.00	1	15319566 (1)
breast cancer	0.00	2	10918184 (1), 10502734 (1)

About this table

Human Genome Epidemiology Navigator: FOSB (3 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/108 PubMed articles for FOSB gene (see all 108 ):

Automated DNA sequencing and analysis of 106 kilobases from human chromosome 19q13.3. (PubMed id 1301997)^{2, 3, 4} Martin-Gallardo A.... Venter J.C. (1992)
Sequence analysis and expression in cultured lymphocytes of the human FOSB gene (G0S3). (PubMed id 8985116)^{1, 3, 4} Heximer S.P.... Forsdyke D.R. (1996)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
A naturally occurring truncated form of FosB that inhibits Fos/Jun transcriptional activity. (PubMed id 1900040)^{1, 3} Nakabeppu Y. and Nathans D. (1991)
An unexpected role for FosB in activation-induced cell death of T cells. (PubMed id 12618758)^{1, 3} Baumann S....Kirchhoff S. (2003)
Placental growth factor induces FosB and c-Fos gene expression via Flt-1 receptors. (PubMed id 14741347)^{1, 3} Holmes D.I. and Zachary I. (2004)
MicroRNA-101 regulates expression of the v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS) oncogene in human hepatocellular carcinoma. (PubMed id 19133651)³ Li S....Zheng X. (2009)
Ectopic expression of delta FBJ murine osteosarcoma viral oncogene homolog B mediates transdifferentiation of adipose-like spheroids into osteo-like microtissues. (PubMed id 18491952)³ Diaz Sanchez-Bustamante C....Fussenegger M. (2008)
Lipopolysaccharide-induced expression of matrix metalloproteinases in human monocytes is suppressed by IFN-gamma via superinduction of ATF-3 and suppression of AP-1. (PubMed id 18802113)³ Ho H.H....Ivashkiv L.B. (2008)
Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey. (PubMed id 18977241)³ Starr J.M....Deary I.J. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 2354	HGNC: 3797	AceView: FOSB	Ensembl:ENSG00000125740	euGenes: HUgn2354
ECgene: FOSB	H-InvDB: FOSB

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for FOSB	Genetics and Cytogenetics in Oncology and Haematology
NIEHS-SNPs	http://egp.gs.washington.edu/data/fosb/

Licensable Technologies for FOSB
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for FOSB:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for FOSB-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for FOSB		Antibodies for FOSB
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for FOSB		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (FOSB)
	Antibodies (FOSB)
	Chimera RNAi (FOSB)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Antibodies & Assays for FOSB

	Recombinant Proteins (Fos B)
	Antibodies (Fos B)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for FOSB

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for FOSB

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

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FOSB Gene at Home site.
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FOSB Gene

protein-coding GIFtS: 63

Aliases &
Descriptions
for FOSB

Summaries
for FOSB

Genomic Location
for FOSB

Proteins
for FOSB

Protein Domains/
Families
for FOSB

Gene Function
for FOSB

Pathways & Interactions
for FOSB

Drugs & Compounds
for FOSB

Transcripts
for FOSB

Expression
for FOSB

Orthologs
for FOSB

Paralogs
for FOSB

SNPs/Variants
for FOSB

Disorders & Mutations
for FOSB

Medical News
for FOSB

Publications
for FOSB

Search for FOSB

Genome Databases showing FOSB

Other Databases showing FOSB

Specialized Databases showing FOSB

Licensable Technologies
for FOSB

Services
for FOSB

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

FOSB Gene

protein-coding GIFtS: 63

Aliases & Descriptionsfor FOSB

Summariesfor FOSB

Genomic Locationfor FOSB

Proteinsfor FOSB

Protein Domains/Familiesfor FOSB

Gene Functionfor FOSB

Pathways & Interactionsfor FOSB

Drugs & Compoundsfor FOSB

Transcriptsfor FOSB

Expression for FOSB

Orthologsfor FOSB

Paralogsfor FOSB

SNPs/Variantsfor FOSB

Disorders & Mutationsfor FOSB

Medical Newsfor FOSB

Publicationsfor FOSB

Search for FOSB

Genome Databases showing FOSB

Other Databases showing FOSB

Specialized Databases showing FOSB

Licensable Technologiesfor FOSB

Servicesfor FOSB

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for FOSB

Summaries
for FOSB

Genomic Location
for FOSB

Proteins
for FOSB

Protein Domains/
Families
for FOSB

Gene Function
for FOSB

Pathways & Interactions
for FOSB

Drugs & Compounds
for FOSB

Transcripts
for FOSB

Expression
for FOSB

Orthologs
for FOSB

Paralogs
for FOSB

SNPs/Variants
for FOSB

Disorders & Mutations
for FOSB

Medical News
for FOSB

Publications
for FOSB

Licensable Technologies
for FOSB

Services
for FOSB