FONG Gene
protein-coding GIFtS: 23
GCID: GC02M200626
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FONG
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Aliases
for FONG gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 7
| Aliases |
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| Uncharacterized LOC3487512 |
| External Ids: | Entrez Gene: 3487512 | Ensembl: ENSG000002261247 | OMIM: 6143085 | UniProtKB: E5RQL43 | | ORGUL members: | |
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| NONCODE:n364514 | |
Export aliases for FONG gene to outside databases
|---|
Summaries
for FONG gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FONG gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_005403.17
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for FONG
Other transcription factors
Search SABiosciences Chromatin IP Primers for FONG
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FONG |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q33.1 Ensembl cytogenetic band: 2q33.1 FONG Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M200626: view genomic region
(about GC identifiers)
Start:
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200,625,259 bp from pter |
End:
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200,715,896 bp from pter |
Size:
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90,638 bases |
Orientation:
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minus strand |
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Proteins
for FONG gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: FONG_HUMAN, E5RQL4 (See
protein sequence)Recommended Name: Formiminotransferase N-terminal subdomain-containing protein precursor Size: 147 amino acids; 16268 DaExplore the universe of human proteins at neXtProt for FONG: NX_E5RQL4
FONG Protein expression data from MOPED and PaxDb: --
ENSEMBL proteins: ENSP00000454447 ENSP00000456442 ENSP00000457780
Human Recombinant Protein Products:
FONG Antibody Products:
Assay Products for FONG: |
Protein
Domains /
Families
for FONG gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FONG for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry E5RQL4ProtoNet protein and cluster: E5RQL4 UniProtKB/Swiss-Prot: FONG_HUMAN, E5RQL4Similarity: Belongs to the formiminotransferase family |
Function
for FONG gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005542 | folic acid binding |
IEA | -- | | GO:0016740 | transferase activity |
IEA | -- |
FONG for ontologies About GeneDecksing
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Pathways & Interactions
for FONG gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FONG
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Drugs & Compounds
for FONG gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FONG
Search CenterWatch for drugs/clinical trials and news about FONG 
|
Transcripts
for FONG gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
Unigene Cluster for FONG: Uncharacterized LOC348751 Hs.734578 [show with all ESTs]Unigene Representative Sequence: AB5684893 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000416668(uc002uvg.3) ENST00000420922 ENST00000420128(uc021vup.1)
Additional cDNA sequence: AB568489.1 BC039445.1 NR_034096.1 8 DOTS entries: DT.91729616 DT.91652094 DT.91729617 DT.120932132 DT.75116953 DT.75189285 DT.95205907 DT.75155697
GeneLoc Exon Structure
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Expression
for FONG gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FONG expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TATCTTTTAA
About this image
Genevestigator expression for FONG
SOURCE GeneReport for Unigene cluster: Hs.734578
UniProtKB/Swiss-Prot: FONG_HUMAN, E5RQL4Tissue specificity: Widely expressed with highest levels in liver and skeletal muscle, and moderate levels in kidney,bone and pancreas
SABiosciences Custom PCR Arrays for FONG
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat FONG | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FONG | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FONG |
Orthologs
for FONG gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of eukaryotes.
Orthologs for FONG gene from 3/7 species (see all 7) About this table
Species with no ortholog for FONG
ENSEMBL Gene Tree for FONG (if available)
TreeFam Gene Tree for FONG (if available) |
Paralogs
for FONG gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FONG gene
- FTCD2
FONG for paralogs About GeneDecksing
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Genomic Variants
for FONG gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for FONG (200625259 - 200715896 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FONG: -- | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for FONG gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
FONG for disorders About GeneDecksing
OMIM gene information: 614308
OMIM disorders: --
1  disease for FONG: About MalaCardsosteoporosis
Export disorders for FONG gene to outside databases
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Publications
for FONG gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FONG gene integrated from 9 sources:
(articles sorted by number of sources associating them with FONG) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Common variants in a novel gene, FONG on chromosome 2 q33.1 confer risk of osteoporosis in Japanese. (PubMed id 21573128)1, 2 Kou I....Ikegawa S. (2011)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for FONG gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing FONG gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing FONG gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FONG gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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About This Section
| Patent Information for FONG gene:
Search GeneIP for patents involving FONG
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FONG gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FONG | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FONG | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FONG | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FONG | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FONG | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FONG |
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| | | | Search Tocris compounds for FONG |
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 | | | | |  |  |  | | | | Search ThermoFisher Antibodies for FONG |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FONG |
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GeneCards Homepage -
Last full update: 19 Mar 2013 -
Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013
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