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FOLR1 Gene

protein-coding   GIFtS: 63

GC11P071578
folate receptor 1 (adult)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: FOLR)
Services    

Aliases &
Descriptions
for FOLR1

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
FBP 2, 3
FOLR 2, 3
FR-alpha 2, 3
MOv18 2
Descriptions
Adult folate-binding protein 3
Folate receptor 1 2, 3
Folate receptor, adult 3
KB cells FBP 3
Ovarian tumor-associated antigen MOv18 3
folate binding protein 2
folate receptor 1 (adult) 2
External Ids
HGNC: 37911
Entrez Gene: 23482
UniProtKB: P153283
Ensembl: ENSG000001101957
Search outside databases for aliases for FOLR1 gene

Previous GC identifers: GC11P074232 GC11P073440 GC11P072123 GC11P071626

Summaries
for FOLR1

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for FOLR1:
The protein encoded by this gene is a member of the folate receptor (FOLR) family. Members of this
gene family have a high affinity for folic acid and for several reduced folic acid derivatives,
and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This gene is composed
of 7 exons; exons 1 through 4 encode the 5' UTR and exons 4 through 7 encode the open reading
frame. Due to the presence of 2 promoters, multiple transcription start sites, and alternative
splicing of exons, several transcript variants are derived from this gene. These variants differ
in the lengths of 5' and 3' UTR, but they encode an identical amino acid sequence.
[provided by RefSeq]

UniProtKB/Swiss-Prot: FOLR1_HUMAN, P15328
Function: Binds to folate and reduced folic acid derivatives and mediates delivery of
5-methyltetrahydrofolate to the interior of cells

Gene Wiki entry for FOLR1 (Folate_receptor_1)

Genomic Location
for FOLR1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the FOLR1 gene  

Entrez Gene cytogenetic band: 11q13.3-q14.1   Ensembl cytogenetic band:  11q13.4   HGNC cytogenetic band: 11q13.3-q14.1

FOLR1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P071578:     (about GC identifiers)

Start:
 71,578,250 bp from pter
End:
 71,585,014 bp from pter
Size:
 6,765 bases
Orientation:
 plus strand
RefSeq DNA sequence:
NC_000011.8  NT_033927.7  

Proteins
for FOLR1

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: FOLR1_HUMAN, P15328 (See protein sequence)
Recommended Name: Folate receptor alpha precursor  
Size: 257 amino acids; 29819 Da
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor. Secreted (Probable)
Secondary accessions: Q53EW2 Q6FGT8 Q6LC90 Q9UCT2

Post-translational modifications:

  • Eight disulfide bonds are present (Probable)1
  • The secreted form is derived from the membrane-bound form either by cleavage of the GPI anchor,
    or/and by proteolysis catalyzed by a metalloprotease1


    • REFSEQ proteins (6 alternative transcripts): 
    NP_000793.1  NP_057936.1  NP_057937.1  NP_057941.1  NP_057942.1  NP_057943.1  


    ENSEMBL proteins: 
    ENSP00000377281 ENSP00000377284 ENSP00000377286 ENSP00000308137 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (Folate Binding Protein)
    Human Recombinant Proteins from Abnova (FOLR1)
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    5 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576 extracellular region IEA--
    GO:0005624 membrane fraction TAS2768245
    GO:0005886 plasma membrane IEA--
    GO:0005887 integral to plasma membrane TAS10633085
    GO:0031225 anchored to membrane IEA--
    About this table

    Antibodies for FOLR1: 
    Browse Antibodies Central at Invitrogen
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse Antibodies at Sigma-Aldrich
    R&D Systems Antibodies for FOLR1
    Antibodies from Abcam (Folate Binding Protein), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (FOLR1)
    Novus Biologicals Antibodies for FOLR1

    Assays for FOLR1: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    Protein Domains/
    Families
    for FOLR1

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro domains/families:
     IPR018143 Folate_rcpt_cons-reg
     IPR004269 Folate_rcpt


       GeneDecks  FOLR1 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry P15328

    ProtoNet protein and cluster: P15328

    1 Blocks protein family: IPB004269 Folate receptor

    UniProtKB/Swiss-Prot: FOLR1_HUMAN, P15328
    Similarity: Belongs to the folate receptor family

    Gene Function
    for FOLR1

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (FOLR1)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (FOLR1)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 6): NM_016724

                  Applied Biosystems Silencer® siRNAs for FOLR1

                  Sigma-Aldrich siRNA and siRNA Panels for FOLR1  
                         Sigma-Aldrich shRNA for FOLR1  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for FOLR1
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 6): NM_000802
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 6): NM_000802
                                     untagged cDNA clones in CMV expression vector (see all 6): NM_000802 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_016731

    UniProtKB/Swiss-Prot: FOLR1_HUMAN, P15328
    Function: Binds to folate and reduced folic acid derivatives and mediates delivery of
    5-methyltetrahydrofolate to the interior of cells

    Genatlas biochemistry entry for FOLR1:
    folate receptor 1,adult

    11 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Folr1):

    craniofacialdigestive/alimentaryembryogenesisendocrine/exocrine glandgrowth/size
    hearing/vestibular/earhomeostasis/metabolismlethality-prenatal/perinatalnervous systemtumorigenesis
    vision/eye

    2 Gene Ontology (GO) molecular function terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004872 receptor activity TAS10633085
    GO:0005542 folic acid binding TAS9545095
    About this table

    Pathways & Interactions
    for FOLR1

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


    1 Sigma-Aldrich "Your Favorite Gene" Pathway for  FOLR1  (Your Favorite Gene powered by Ingenuity) 
     Virus Entry via Endocytic Pathways

       GeneDecks  FOLR1 for the pathways selected above  
    About GeneDecksing


    5/7 Interacting proteins for FOLR1 (ENSP000003081373) via UniProtKB, MINT, and/or STRING (see all 7 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FGF3ENSP000003341223STRING (score=.753)
    ITLN1ENSP000003235873STRING (score=.75)
    RAD51ENSP000003720883STRING (score=.75)
    SIRPAENSP000003483073STRING (score=.746)
    RFC1ENSP000003713213STRING (score=.73)
    About this table

    3 Gene Ontology (GO) biological process terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006898 receptor-mediated endocytosis TAS9545095
    GO:0015884 folic acid transport TAS9545095
    GO:0046655 folic acid metabolic process IEA--
    About this table

    Drugs & Compounds
    for FOLR1

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for FOLR1
    10/11 Novoseek chemical compound relationships for FOLR1 gene (see all 11 )
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    5-methyltetrahydrofolate 87.54 19 15094208 (2), 9099956 (2), 9178098 (2), 14704289 (2) (see all 12)
    dihydrofolate 44.84 2 17534577 (1), 12416030 (1)
    n-hydroxysuccinimide 44.25 1 9426700 (1)
    homocysteine 42.03 5 11169018 (1), 15641086 (1), 16453285 (1)
    mspi 28.38 1 7511899 (1)
    whey 26.10 4 8318019 (1), 10759136 (1)
    methionine 26.07 5 10332959 (1), 1900444 (1), 9301457 (1)
    gadolinium 2.36 1 17193622 (1)
    oligonucleotide 0.00 1 17582475 (1)
    lipid 0.00 1 12202950 (1)
    About this table


    Transcripts
    for FOLR1

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (FOLR1)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (FOLR1)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 6): NM_016724

                  Sigma-Aldrich siRNA and siRNA Panels for FOLR1  
                         Sigma-Aldrich shRNA for FOLR1  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_000802  NM_016724  NM_016725  NM_016729  NM_016730  NM_016731  

    REFSEQ mRNAs for FOLR1 gene (6 alternative transcripts): 

    NM_000802.2   NM_016724.1   NM_016725.1   NM_016729.1   NM_016730.1   NM_016731.2   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_000802  NM_016724  NM_016725  NM_016729  NM_016730  NM_016731  

                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 6): NM_000802
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 6): NM_000802
                                     untagged cDNA clones in CMV expression vector (see all 6): NM_000802 

    Additional cDNA sequence: 

    AF000381.2 AK223527.1 BC002947.2 BT007158.1 CR542019.1 CR607460.1 CR613077.1 CR623060.1 
    J05013.1 M25317.1 M28099.1 S73474.1 U78793.1 U78794.1 X62753.1 

    5 DOTS entries:

    DT.100770176  DT.447922  DT.95103787  DT.100770180  DT.100770179 

    24/185 AceView cDNA sequences (see all 185 ):

    U78793 N29700 M28099 AA488506 NM_000802 BE744857 R24620 AA436422 
    BI913499 NM_016724 R26895 CB242517 BQ017257 NM_016730 AA425789 AL555980 
    BC002947 CR542019 AA291206 NM_016729 CR613077 BG328933 BE901231 S73474 

    highest scoring ESTs for FOLR1:

    AF000381 AA132971 AA179594 AA181711 AA182646 AA188982 AA191102 AA191618 AA235638 AA291206 

    Unigene Cluster for FOLR1:

    Folate receptor 1 (adult)
    Hs.73769  [show with all ESTs]
    Unigene Representative Sequence: NM_016730


    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for FOLR1

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b
    SP1:              -                                       
    SP2:              -     -                                 
    SP3:                                                      

    About this scheme

    ECgene alternative splicing isoforms for FOLR1

    4 Ensembl transcripts including schematic representations:
    ENST00000393676  ENST00000393679  ENST00000393681  ENST00000312293  

    Expression
    for FOLR1

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    FOLR1 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for FOLR1

    1 / 2 / 3

    5 probe-sets matching FOLR1 gene


    		Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    821_s_at2, 3 U95-A 1 1.00 1.00 0.95 0.78 U78793 0.80 0.88 0.84 1

    		534_s_at2, 3 U95-A 2 1.00 0.97 0.85 1.59 U20391 0.20 1.00 0.72 1
    39311_at2, 3 U95-A 2 1.00 0.88 0.95 0.72 AF000381 1.00 0.90 0.95 1

    		204437_s_at2, 3 U133-A 1 1.00 1.00 -- -- NM_016725 0.60 0.83 0.73 1

    		204437_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    GeneDecks  FOLR1 for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: GTCGGGCCTC

    SOURCE GeneReport for Unigene cluster: Hs.73769

    Expression variation in blood from EXPOLDB for FOLR1

    UniProtKB/Swiss-Prot: FOLR1_HUMAN, P15328
    Tissue specificity: Exclusively expressed in tissues of epithelial origin. Expression is increased
    in malignant tissues. Expressed in kidney, lung and cerebellum

    Orthologs
    for FOLR1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for FOLR1 gene from 5/7 species (see all 7 )
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 FOLR11   -- folate receptor 1 (adult) 85.45(n)
    80.95(a)    		 609612  XM_846900.1  XP_851993.1 
    cow
    (Bos taurus)    		 FOLR11   -- folate receptor 1 (adult) 81.3(n)
    76.83(a)    		 539750  XM_589186.3  XP_589186.3 
    rat
    (Rattus norvegicus)    		 Folr11   -- folate receptor 1 (adult) 80.52(n)
    77.25(a)    		 171049  NM_133527.1  NP_598211.1 
    mouse
    (Mus musculus)    		 Folr11, 5 75
    		 folate receptor 1 (adult)1, 5 81.05(n)1
    78.82(a)1    		 142751  NM_008034.21  NP_032060.21 
     AF0963195  AF0963205  (see all 16)
    chicken
    (Gallus gallus)    		 FOLR11   -- folate receptor 1 (adult) 69.29(n)
    66.2(a)    		 395638  NM_204834.1  NP_990165.1 
    About this table        Species with no ortholog for FOLR1

    ENSEMBL Gene Tree for FOLR1

    Paralogs
    for FOLR1

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for FOLR1 gene
    FOLR32  FOLR42  FOLR22  

    SNPs/Variants
    for FOLR1

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/49 NCBI SNPs in FOLR1 are shown (see all 49 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 23)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 11 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ------------
    rs15400871,2
    		A,C,F,H71579139(-) GCTTTC/TTCCTG 6 -- ut51 ng51 int117Minor allele frequency- T:0.07EA NA MN EU WA CSAM 1358
    rs71092501,2
    		A,C,F,H71579318(+) TTCTCC/TGGCGT 6 -- int1 ng51 ut5111Minor allele frequency- T:0.09EU EA WA NA 980
    rs20710101,2
    		C,F,H,O71578612(+) TCAAGG/ATTAAA 4 -- int1 ut51 ng5117Minor allele frequency- A:0.13EA NA EU WA 2860
    rs71251891,2
    		A,C,F,H71579493(+) CTTATA/CTGAGC 6 -- int1 ng514Minor allele frequency- C:0.09EU EA WA 420
    rs4990871,2
    		C,F,H71578892(-) CAGTGG/AAGCCC 6 -- ng51 int116Minor allele frequency- A:0.01EA NA MN EU WA CSAM 1324
    rs37637961,2
    		C,F,H71579893(-) GGACAT/CGGGTG 6 -- int1 ng514Minor allele frequency- C:0.09EU EA WA 420
    rs79286491,2
    		A,C,H71580947(+) TTGCAT/CGGGCC 6 R/W mis1 ese35Minor allele frequency- C:0.00EU EA WA 590
    --
    rs38337481,2
    		C,F71579110(-) AGGGGG/-AAATC 6 -- ng51 int1 ut51 trp35Minor allele frequency- -:0.04MN CSAM EA 400
    --
    rs79285311,2
    		A71580851(+) CTCTTC/TCTTCA 6 -- ng51 int1 ut51 trp30--------
    --
    rs79383031,2
    		A71580830(+) CCTTGC/GTGCCA 6 -- ng51 int1 ut510--------
    About this table

    HapMap Linkage Disequilibrium images for FOLR1 (up to first 250kb)

    Disorders & Mutations
    for FOLR1

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    		 OMIM: 136430

    10/25 Novoseek disease relationships for FOLR1 gene (see all 25 )

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    ovarian carcinoma 70.70 42 9426700 (4), 9218736 (4), 8242637 (3), 9500461 (2) (see all 19)
    folate deficiency 69.66 4 9301457 (2), 8126512 (1), 15641086 (1)
    leukemia l1210 56.21 1 7579732 (1)
    ovarian cancer 55.70 18 1717147 (2), 16908932 (2), 9583724 (1), 17062694 (1) (see all 13)
    anencephaly 44.62 1 17035141 (1)
    tumors 37.00 53 18222534 (5), 16453285 (4), 12874029 (3), 9178098 (2) (see all 24)
    choriocarcinoma 35.17 5 8061055 (2)
    spina bifida 34.56 1 10234517 (1)
    cancer 31.39 21 10632363 (3), 18318652 (2), 8920973 (1), 8595169 (1) (see all 12)
    ovarian neoplasms 31.36 1 10542886 (1)
    About this table

    Human Gene Mutation Database: FOLR1
    Genetic Association Database: FOLR1
    Human Genome Epidemiology Navigator: FOLR1 (11 documents)

    Medical News
    for FOLR1

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for FOLR1

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/190 PubMed articles for FOLR1 gene (see all 190 ):

    Search for FOLR1

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing FOLR1

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 2348 HGNC: 3791 AceView: FOLR1 Ensembl:ENSG00000110195 euGenes: HUgn2348
    ECgene: FOLR1 H-InvDB: FOLR1

    Other Databases showing FOLR1

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing FOLR1

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    ATLAS Chromosomes in Cancer entry for FOLR1 Genetics and Cytogenetics in Oncology and Haematology

    Licensable Technologies
    for FOLR1

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for FOLR1

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for FOLR1:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for FOLR1-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for FOLR1 Browse antibodies at Sigma-Aldrich
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