FNTB Gene
protein-coding GIFtS: 62
GCID: GC14P065454
|
|
farnesyltransferase, CAAX box, beta
| |
Aliases
for FNTB gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Farnesyltransferase, CAAX Box, Beta1 2 | | CAAX Farnesyltransferase Subunit Beta2 3 | | FPTB1 2 | | EC 2.5.1.583 8 | | Ras Proteins Prenyltransferase Subunit Beta2 3 | | Protein Farnesyltransferase Subunit Beta2 | | FTase-Beta1 | | |
Export aliases for FNTB gene to outside databasesPrevious GC identifers: GC14P062781 GC14P059247 GC14P063443 GC14P064523 GC14P065381 |
Summaries
for FNTB gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: FNTB_HUMAN, P49356Function: Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth positionfrom the C-terminus of several proteins. The beta subunit is responsible for peptide-binding
Gene Wiki entry for FNTB
|
Genomic Views
for FNTB gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000014.8 NC_018925.1 NT_026437.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FNTB gene promoter:
RFX1 C/EBPbeta USF1 FOXF2 Egr-1 Nkx2-2 Arnt USF-1 c-Myb Pax-4a
Other transcription factors
Search SABiosciences Chromatin IP Primers for FNTB
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FNTB |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 14q23.3 Ensembl cytogenetic band: 14q23.3 HGNC cytogenetic band: 14q23.3FNTB Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14P065454: view genomic region
(about GC identifiers)
Start:
|
65,453,438 bp from pter |
End:
|
65,529,370 bp from pter |
Size:
|
75,933 bases |
Orientation:
|
plus strand |
|
Proteins
for FNTB gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: FNTB_HUMAN, P49356 (See
protein sequence)Recommended Name: Protein farnesyltransferase subunit beta Size: 437 amino acids; 48774 Da
Cofactor: Binds 1 zinc ion per subunit
Subunit: Heterodimer of an alpha and a beta subunit
6/14 PDB 3D structures from  and Proteopedia  for FNTB (see all 14):1JCQ (3D)
1LD7 (3D)
1LD8 (3D)
1MZC (3D)
1S63 (3D)
1SA4 (3D)
Secondary accessions: B2RDX6Explore the universe of human proteins at neXtProt for FNTB: NX_P49356
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P49356
4/7 DME Specific Peptides for FNTB (P49356) (see all 7)
FNTB Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_002019.1
ENSEMBL proteins: ENSP00000246166 ENSP00000451722
Human Recombinant Protein Products for FNTB:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
FNTB for ontologies About GeneDecksing
FNTB Antibody Products:
Assay Products for FNTB: |
Protein
Domains /
Families
for FNTB gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FNTB for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P49356ProtoNet protein and cluster: P49356 1 Blocks protein family: IPB001330 Prenyltransferase/squalene oxidase
UniProtKB/Swiss-Prot: FNTB_HUMAN, P49356Similarity: Belongs to the protein prenyltransferase subunit beta familySimilarity: Contains 5 PFTB repeats |
Function
for FNTB gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: FNTB_HUMAN, P49356Function: Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth positionfrom the C-terminus of several proteins. The beta subunit is responsible for peptide-bindingCatalytic activity: Farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate Genatlas biochemistry entry for FNTB:CAAX farnesyltransferase,beta subunit,promoting the prenylation of Ras,first step of a series of post translationalmodification of RAS,required for its association with the inner surface of the plasma membrane,also involved inmaturation of other proteins including Ras family members,the gamma subunit of G proteins and nuclear lamins
Enzyme Number (IUBMB): EC 2.5.1.581 2
Gene Ontology (GO): 5/8 molecular function terms (GO ID links to tree view) (see all 8): About this table
FNTB for ontologies About GeneDecksing
Phenotypes:
10 MGI mutant phenotypes (inferred from 4 alleles ) (MGI details for Fntb):
FNTB for phenotypes About GeneDecksing
Animal Models:
Mouse knock-outs for FNTB: Fntbtm1.2Mbrg Fntbtm1.1Bbd
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FNTB (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FNTB (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FNTB (NM_002028) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FNTB | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FNTB |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FNTB |
|
Pathways & Interactions
for FNTB gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | G-protein signaling K-RAS regulation pathway | | | 2 | G-protein signaling_RhoA regulation pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 EMD Millipore Pathways for FNTB
3  GeneGo (Thomson Reuters) Pathways for FNTB
FNTB for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FNTB
STRING Interaction
Network Preview (showing 5 interactants - click image to see 19)
5/46 Interacting proteins for FNTB (P493561, 2, 3 ENSP000002461664) via UniProtKB, MINT, STRING, and/or I2D (see all 46)About this table
Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008284 | positive regulation of cell proliferation |
-- | -- | | GO:0008285 | negative regulation of cell proliferation |
-- | -- | | GO:0010035 | response to inorganic substance |
-- | -- | | GO:0014070 | response to organic cyclic compound |
-- | -- | | GO:0018343 | protein farnesylation |
IDA | 19228685 |
FNTB for ontologies About GeneDecksing
|
Drugs & Compounds
for FNTB gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FNTB
1 HMDB Compound for FNTB About this table
10 DrugBank Compounds for FNTB About this table
| Compound | Synonyms |
CAS
# | Type | Actions | PubMed Ids |
|---|
| (11S)-8-CHLORO-11-[1-(METHYLSULFONYL)PIPERIDIN-4-YL]-6-PIPERAZIN-1-YL-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDINE | -- | -- | target | -- | 10592235 | | (20S)-19,20,21,22-TETRAHYDRO-19-OXO-5H-18,20-ETHANO-12,14-ETHENO-6,10-METHENO-18H-BENZ[D]IMIDAZO[4,3-K][1,6,9,12]OXATRIAZA-CYCLOOCTADECOSINE-9-CARBONITRILE | -- | -- | target | -- | 10592235 | | (20S)-19,20,22,23-TETRAHYDRO-19-OXO-5H,21H-18,20-ETHANO-12,14-ETHENO-6,10-METHENOBENZ[D]IMIDAZO[4,3-L][1,6,9,13]OXATRIAZACYCLONOADECOSINE-9-CARBONITRILE | -- | -- | target | -- | 10592235 | | 2-CHLORO-5-(3-CHLORO-PHENYL)-6-[(4-CYANO-PHENYL)-(3-METHYL-3H-IMIDAZOL-4-YL)- METHOXYMETHYL]-NICOTINONITRILE | -- | -- | target | -- | 10592235 | | 4-[(5-{[4-(3-CHLOROPHENYL)-3-OXOPIPERAZIN-1-YL]METHYL}-1H-IMIDAZOL-1-YL)METHYL]BENZONITRILE | -- | -- | target | -- | 10592235 | | ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID | -- | -- | target | -- | 10592235 | | FARNESYL | -- | -- | target | -- | 10592235 | | FARNESYL DIPHOSPHATE | -- | -- | target | -- | 10592235 | | GERANYLGERANYL DIPHOSPHATE | -- | -- | target | -- | 10592235 | | [(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID | -- | -- | target | -- | 10592235 |
Search CenterWatch for drugs/clinical trials and news about FNTB
|
Transcripts
for FNTB gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FNTB gene: NM_002028.3 Unigene Cluster for FNTB: Farnesyltransferase, CAAX box, beta Hs.325531 [show with all ESTs]Unigene Representative Sequence: NM_0012025598 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000246166(uc010tsl.2 uc010tsm.2 uc001xia.3) ENST00000555372
ENST00000555742 ENST00000554210 ENST00000554334 ENST00000556709 ENST00000555618
ENST00000557300
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FNTB (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FNTB (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FNTB (NM_002028) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FNTB | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FNTB |
Additional cDNA sequence: AK093298.1 AK225917.1 AK295972.1 AK315714.1 BC013574.1 BC020232.1 BC035148.1 BC052775.1 BX248269.1 L00635.1 L10414.1 16 DOTS entries: DT.444290 DT.91732520 DT.100835090 DT.75149664 DT.100840472 DT.120751748 DT.100789404 DT.100738434 DT.100789405 DT.92427119 DT.100692416 DT.100705079 DT.120751814 DT.91680670 DT.97805221 DT.92024014 24/225 AceView cDNA sequences (see all 225): CR618315 BU153989 AA873486 BM674471 BX394424 BU740458 BM809674 BE407340 BG676869 CA420933 BC020232 BM852620 AI347875 BX952567 AW262685 BM672130 BQ218949 BC013574 BE221171 BQ226383 W49805 BX383952 W74655 AI244817
GeneLoc Exon Structure
|
Expression
for FNTB gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FNTB expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGGCGCTTAG
About this image
See FNTB Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FNTB
SOURCE GeneReport for Unigene cluster: Hs.325531
SABiosciences Custom PCR Arrays for FNTB
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FNTB
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FNTB | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FNTB | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FNTB | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FNTB |
Orthologs
for FNTB gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for FNTB gene from 8/35 species (see all 35) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
LOC1008576831 |
protein farnesyltransferase subunit beta-like |
76.42(n)
83.73(a) |
|
100857683 XM_003643780.1 XP_003643828.1 |
lizard
(Anolis carolinensis) |
Reptilia |
FNTB6 |
-- |
82(a) |
1 → many |
1(93647375-93662482) |
zebrafish
(Danio rerio) |
Actinopterygii |
570450492 |
-- |
76.32(n) |
|
57045049 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG175651 , 3 |
RAB-protein geranylgeranyltransferase3
CG175651 |
52(a)3
57.31(n)1
53.74(a)1 |
|
419891 NM_142283.31 NP_650540.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
F23B12.63
fntb-11 |
protein farnesyltransferase beta subunit3
Protein FNTB-11 |
46(a)3
51.01(n)1
48.07(a)1 |
|
V(14450340-14452041)3
1799461 NM_074179.41 NP_506580.11 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
RAM1(YDL090C)4
RAM11 |
Beta subunit of the CAAX farnesyltransferase (FTase) more4
Ram1p1 |
46.5(n)1
42.54(a)1 |
|
4(296329-295034)4
8514681, 4 NP_010193.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
ERA11 |
protein farnesyltransferase subunit beta |
54.25(n)
49.22(a) |
|
834026 NM_123392.1 NP_198844.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.209912 |
Oryza sativa (japonica cultivar-group) putative farnesyltranstransferase more |
74.79(n) |
|
NM_191123.1 |
ENSEMBL Gene Tree for FNTB (if available)
TreeFam Gene Tree for FNTB (if available) |
Paralogs
for FNTB gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FNTB gene
- CHURC1-FNTB2
1 SIMAP similar gene for FNTB using alignment to 2 protein entries: FNTB_HUMAN (see all proteins):CHURC1-FNTB
FNTB for paralogs About GeneDecksing
|
Genomic Variants
for FNTB gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 14 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FNTB (65453438 - 65529370 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for FNTB
1 CNV: 101971 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FNTB |
|
Disorders
/ Diseases
for FNTB gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
FNTB for disorders About GeneDecksing
OMIM gene information: 134636
OMIM disorders: --
1  disease for FNTB: About MalaCardscolorectal cancer
Human Genome Epidemiology (HuGE) Navigator: FNTB (1 document)
Export disorders for FNTB gene to outside databases
|
Publications
for FNTB gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FNTB gene, integrated from 9 sources (see all 38):
(articles sorted by number of sources associating them with FNTB) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- cDNA cloning of the two subunits of human CAAX farnesyltransferase and chromosomal mapping of FNTA and FNTB loci and related sequences. (PubMed id 8276393)1, 2, 3 Andres D.A.... Francke U. (1993)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Dual protein farnesyltransferase-geranylgeranyltransferase-I inhibitors as potential cancer chemotherapeutic agents. (PubMed id 12825937)1, 2 deSolms S.J.... Taylor J.S. (2003)
- 3-aminopyrrolidinone farnesyltransferase inhibitors: design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency. (PubMed id 12036349)1, 2 Bell I.M.... Zartman C.B. (2002)
- The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics. (PubMed id 11687658)1, 2 Long S.B.... Beese L.S. (2001)
- Characterization of recombinant human farnesyl-protein transferase: cloning, expression, farnesyl diphosphate binding, and functional homology with yeast prenyl-protein transferases. (PubMed id 8494894)1, 2 Omer C.A.... Kohl N.E. (1993)
- Expression of farnesyltransferase in primary liver can cer. (PubMed id 22882915)1 Sui G.D....Hu S.Y. (2012)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
- Expansion of protein farnesyltransferase specificity u sing 'tunable' active site interactions: development of bioengineered prenylation pathways. (PubMed id 22992747)1 Hougland J.L....Fierke C.A. (2012)
|
External Searches for FNTB gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FNTB gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FNTB gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FNTB gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FNTB | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FNTB gene:
Search GeneIP for patents involving FNTB
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for FNTB gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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| | |  | OriGene Antibodies for FNTB | | OriGene shRNA RFP for FNTB | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FNTB | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FNTB | | | OriGene Protein Over-expression Lysate for FNTB | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FNTB | | OriGene 3'-UTR Clone for FNTB | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FNTB | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FNTB | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for FNTB | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FNTB | | OriGene Custom Protein Services for FNTB | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FNTB | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FNTB | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FNTB | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FNTB | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FNTB | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FNTB |
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| | | | Search Tocris compounds for FNTB |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FNTB |
|  |  |  |  | | | | ThermoFisher Antibodies for FNTB |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FNTB |
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