FNDC7 Gene
protein-coding GIFtS: 38
GCID: GC01P109255
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fibronectin type III domain containing 7
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Aliases
for FNDC7 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Fibronectin Type III Domain Containing 71 2 | | FLJ358381 | | RP11-293A10.22 | | Fibronectin Type III Domain-Containing Protein 72 |
Export aliases for FNDC7 gene to outside databasesPrevious GC identifers: GC01P108978 GC01P109066 GC01P107149 |
Summaries
for FNDC7 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FNDC7 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FNDC7 gene promoter:
Nkx3-1 v4 FOXF2 Bach2 CUTL1 Nkx2-5 LCR-F1 HNF-1A AREB6 GATA-6 HNF-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for FNDC7
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FNDC7 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p13.3 Ensembl cytogenetic band: 1p13.3 HGNC cytogenetic band: 1p13.3FNDC7 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P109255: view genomic region
(about GC identifiers)
Start:
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109,255,279 bp from pter |
End:
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109,285,371 bp from pter |
Size:
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30,093 bases |
Orientation:
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plus strand |
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Proteins
for FNDC7 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: FNDC7_HUMAN, Q5VTL7 (See
protein sequence)Recommended Name: Fibronectin type III domain-containing protein 7 precursor Size: 733 amino acids; 78236 Da
Subcellular location: Secreted (Potential)
Sequence caution: Sequence=AAH57762.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=AAI30422.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAC04077.1;Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=CAH72065.1; Type=Erroneous gene modelprediction;
Secondary accessions: A1L468 E9PAZ5 Q6PF16 Q8NA51Explore the universe of human proteins at neXtProt for FNDC7: NX_Q5VTL7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q5VTL7
FNDC7 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001138409.1
ENSEMBL proteins: ENSP00000359034 ENSP00000405986 ENSP00000271311
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005576 | extracellular region |
IEA | -- |
FNDC7 for ontologies About GeneDecksing
FNDC7 Antibody Products:
Assay Products for FNDC7: |
Protein
Domains /
Families
for FNDC7 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FNDC7 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q5VTL7ProtoNet protein and cluster: Q5VTL7 UniProtKB/Swiss-Prot: FNDC7_HUMAN, Q5VTL7Similarity: Contains 8 fibronectin type-III domains |
Function
for FNDC7 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FNDC7 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FNDC7
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FNDC7 (NM_001144937) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FNDC7 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FNDC7 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FNDC7 |
|
Pathways & Interactions
for FNDC7 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FNDC7
STRING Interaction
Network Preview (showing 5 interactants - click image to see more details)
5 Interacting proteins for FNDC7 (ENSP000003590344) via UniProtKB, MINT, STRING, and/or I2DAbout this table
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Drugs & Compounds
for FNDC7 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FNDC7
Search CenterWatch for drugs/clinical trials and news about FNDC7
|
Transcripts
for FNDC7 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FNDC7 gene (2 alternative transcripts): NM_001144937.1 NM_173532.1 Unigene Cluster for FNDC7: Fibronectin type III domain containing 7 Hs.258253 [show with all ESTs]Unigene Representative Sequence: NM_0011449373 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000370017(uc001dvx.3) ENST00000445274 ENST00000271311(uc010ova.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FNDC7 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FNDC7
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FNDC7 (NM_001144937) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FNDC7 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FNDC7 |
Additional cDNA sequence: AK093157.1 BC057762.1 BC130421.1 BC144218.1 1 DOTS entry: DT.40283888 10 AceView cDNA sequences: BF059694 NM_173532 AK093157 BC057762 AW515726 AX747961 AW590959 BI462645 BI464650 AI908529
GeneLoc Exon Structure
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Expression
for FNDC7 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FNDC7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGAGAAGATG
About this image
See FNDC7 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FNDC7
SOURCE GeneReport for Unigene cluster: Hs.258253
SABiosciences Custom PCR Arrays for FNDC7
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FNDC7
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FNDC7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FNDC7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FNDC7 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FNDC7 |
Orthologs
for FNDC7 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for FNDC7 gene from 4/11 species (see all 11) About this table
ENSEMBL Gene Tree for FNDC7 (if available)
TreeFam Gene Tree for FNDC7 (if available) |
Paralogs
for FNDC7 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for FNDC7 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FNDC7 (109255279 - 109285371 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FNDC7: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FNDC7 |
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Disorders
/ Diseases
for FNDC7 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for FNDC7 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FNDC7 gene integrated from 9 sources:
(articles sorted by number of sources associating them with FNDC7) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
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External Searches for FNDC7 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing FNDC7 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FNDC7 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FNDC7 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FNDC7 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for FNDC7 gene:
Search GeneIP for patents involving FNDC7
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FNDC7 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FNDC7 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FNDC7 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FNDC7 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FNDC7 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FNDC7 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FNDC7 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FNDC7 | | OriGene Custom Protein Services for FNDC7 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FNDC7 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FNDC7 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FNDC7 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FNDC7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FNDC7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FNDC7 |
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| | | | Search Tocris compounds for FNDC7 |
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 | | | FNDC7 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FNDC7 |
|  |  |  | | | | Search ThermoFisher Antibodies for FNDC7 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FNDC7 |
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