Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



FNDC4 Gene

protein-coding   GIFtS: 45
GCID: GC02M027714

Fibronectin Type III Domain Containing 4

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Fibronectin Type III Domain Containing 41 2
FRCP12 3 5
Fibronectin Type III Repeat-Containing Protein 12 3
Fibronectin Type III Domain-Containing Protein 42

External Ids:    HGNC: 202391   Entrez Gene: 648382   Ensembl: ENSG000001152267   OMIM: 6119055   UniProtKB: Q9H6D83   

Export aliases for FNDC4 gene to outside databases

Previous GC identifers: GC02M027689 GC02M027626 GC02M027568 GC02M027456


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for FNDC4 Gene:
FNDC4 (fibronectin type III domain containing 4) is a protein-coding gene. Diseases associated with FNDC4 include kidney disease. An important paralog of this gene is FNDC5.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
Regulatory elements:
   Regulatory transcription factor binding sites in the FNDC4 gene promoter:
         CREB   deltaCREB   LCR-F1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFNDC4 promoter sequence
   Search Chromatin IP Primers for FNDC4

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FNDC4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p23.3   Ensembl cytogenetic band:  2p23.3   HGNC cytogenetic band: 2p23.3

FNDC4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FNDC4 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M027714:  view genomic region     (about GC identifiers)

Start:
27,714,750 bp from pter      End:
27,718,126 bp from pter
Size:
3,377 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: FNDC4_HUMAN, Q9H6D8 (See protein sequence)
Recommended Name: Fibronectin type III domain-containing protein 4 precursor  
Size: 234 amino acids; 25159 Da
Secondary accessions: D6W560

Explore the universe of human proteins at neXtProt for FNDC4: NX_Q9H6D8

Explore proteomics data for FNDC4 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn52, Asn97, Asn147
  • Modification sites at PhosphoSitePlus

  • See FNDC4 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_073734.1  
    ENSEMBL proteins: 
     ENSP00000264703  

    FNDC4 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for FNDC4
    OriGene Protein Over-expression Lysate for FNDC4
    OriGene MassSpec for FNDC4
    OriGene Custom Protein Services for FNDC4
    GenScript Custom Purified and Recombinant Proteins Services for FNDC4
    Novus Biologicals FNDC4 Proteins
    Novus Biologicals FNDC4 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for FNDC4

    FNDC4 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for FNDC4
    OriGene Custom Antibody Services for FNDC4
    Novus Biologicals FNDC4 Antibodies
    Abcam antibodies for FNDC4
    Cloud-Clone Corp. Antibodies for FNDC4
    Search ThermoFisher Antibodies for FNDC4
    LSBio Antibodies in human, mouse, rat for FNDC4

    FNDC4 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for FNDC4
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for FNDC4
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for FNDC4
    Cloud-Clone Corp. CLIAs for FNDC4


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    FN3: Fibronectin type III domain containing

    2 InterPro protein domains:
     IPR003961 Fibronectin_type3
     IPR013783 Ig-like_fold

    Graphical View of Domain Structure for InterPro Entry Q9H6D8

    ProtoNet protein and cluster: Q9H6D8

    UniProtKB/Swiss-Prot: FNDC4_HUMAN, Q9H6D8
    Similarity: Contains 1 fibronectin type-III domain


    FNDC4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    FNDC4 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FNDC4
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FNDC4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FNDC4
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FNDC4

    miRNA
    Products:
        
    miRTarBase miRNAs that target FNDC4:
    hsa-mir-7-5p (MIRT025717), hsa-mir-124-3p (MIRT022409)

    Block miRNA regulation of human, mouse, rat FNDC4 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FNDC4 (see all 29):
    hsa-miR-125a-3p hsa-miR-331-3p hsa-miR-128 hsa-miR-301a hsa-miR-3921 hsa-miR-583 hsa-miR-3605-5p hsa-miR-4314
    SwitchGear 3'UTR luciferase reporter plasmidFNDC4 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for FNDC4
    Predesigned siRNA for gene silencing in human, mouse, rat FNDC4

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for FNDC4

    Clone
    Products:
         
    OriGene clones in human, mouse for FNDC4 (see all 6)
    OriGene ORF clones in mouse, rat for FNDC4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FNDC4 (NM_022823)
    Sino Biological Human cDNA Clone for FNDC4
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FNDC4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FNDC4

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for FNDC4
    Browse ESI BIO Cell Lines and PureStem Progenitors for FNDC4 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FNDC4


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    FNDC4_HUMAN, Q9H6D8: Membrane; Single-pass type I membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum4
    plasma membrane4
    cytosol1
    extracellular1
    golgi apparatus1
    mitochondrion1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005783endoplasmic reticulum ISS--
    GO:0005886plasma membrane ISS--
    GO:0016021integral component of membrane IEA--

    FNDC4 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus




        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FNDC4
    Interactions:

        Search GeneGlobe Interaction Network for FNDC4

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for FNDC4 (ENSP000002647034) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    POLR2GENSP000003017884STRING: ENSP00000301788
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FNDC4



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for FNDC4 gene: 
    NM_022823.2  

    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000264703(uc002rkx.3) ENST00000491414 ENST00000476197
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat FNDC4 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FNDC4 (see all 29):
    hsa-miR-125a-3p hsa-miR-331-3p hsa-miR-128 hsa-miR-301a hsa-miR-3921 hsa-miR-583 hsa-miR-3605-5p hsa-miR-4314
    SwitchGear 3'UTR luciferase reporter plasmidFNDC4 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for FNDC4
    Predesigned siRNA for gene silencing in human, mouse, rat FNDC4
    Clone
    Products:
         
    OriGene clones in human, mouse for FNDC4 (see all 6)
    OriGene ORF clones in mouse, rat for FNDC4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FNDC4 (NM_022823)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FNDC4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FNDC4
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for FNDC4
    OriGene qSTAR qPCR primer pairs in human, mouse for FNDC4
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FNDC4
      QuantiTect SYBR Green Assays in human, mouse, rat FNDC4
      QuantiFast Probe-based Assays in human, mouse, rat FNDC4

    Selected AceView cDNA sequences (see all 136):

    AK026015 CF128581 BI753191 CR625278 BX282467 CR606989 NM_022823 AA983819 
    BQ014319 BQ948274 Z44980 BF109870 Z40716 BM547385 BM923672 CR599669 
    CR597122 AI954667 CR605204 CR620289 AI380721 BX449110 AI467781 AY358136 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for FNDC4    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b
    SP1:                    -                       -               
    SP2:                    -                                       
    SP3:                                                            
    SP4:                                      -     -               


    ECgene alternative splicing isoforms for FNDC4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    FNDC4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGCCTCAGG
    FNDC4 Expression
    About this image

    FNDC4 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FNDC4 Protein Expression
        Custom PCR Arrays for FNDC4
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for FNDC4
    OriGene qSTAR qPCR primer pairs in human, mouse for FNDC4
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FNDC4
    QuantiTect SYBR Green Assays in human, mouse, rat FNDC4
    QuantiFast Probe-based Assays in human, mouse, rat FNDC4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FNDC4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for FNDC4 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fndc41 , 5 fibronectin type III domain containing 41, 5 89.28(n)1
    96.48(a)1
      5 (17.27 cM)5
    643391  NM_022424.51  NP_071869.21 
     312922555 
    chicken
    (Gallus gallus)
    Aves FNDC41 fibronectin type III domain containing 4 69.77(n)
    70.7(a)
      421981  XM_004935800.1  XP_004935857.1 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia fndc41 fibronectin type III domain containing 4 67.49(n)
    67.98(a)
      100127578  NM_001112944.1  NP_001106415.1 
    zebrafish
    (Danio rerio)
    Actinopterygii fndc4a1 fibronectin type III domain containing 4a 66.67(n)
    66.15(a)
      567985  XM_691297.5  XP_696389.3 


    ENSEMBL Gene Tree for FNDC4 (if available)
    TreeFam Gene Tree for FNDC4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for FNDC4 gene
    FNDC52  
    1 SIMAP similar gene for FNDC4 using alignment to 1 protein entry:     FNDC4_HUMAN:
    FNDC5

    FNDC4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for FNDC4 (see all 82)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs728195431,2
    C--27714592(+) CTGGGA/GTTAGT 1 -- int10--------
    rs1900650181,2
    --27714618(+) TTCCTG/TGCCCT 1 -- int10--------
    rs1823892611,2
    --27714680(+) ATGGTA/GTAAGG 1 -- int10--------
    rs31804201,2
    C--27714751(-) AACTGG/AAGCTG 1 -- ut31 ese31Minor allele frequency- A:0.00NA 2
    rs99741,2
    C,H--27714971(+) AAGATG/TTGGGG 1 -- ut31 ese33Minor allele frequency- T:0.00MN NS NA 412
    rs1394372071,2
    C--27715106(+) ATCCAC/TTCCCC 1 -- ut310--------
    rs1422537061,2
    C--27715113(+) CCCCAC/GGTCCA 1 -- ut310--------
    rs91881,2
    C,F,H--27715125(-) AGTCTG/ATGCCC 1 -- ut31 ese36Minor allele frequency- A:0.04MN NS WA 1092
    rs1464044551,2
    --27715145(+) CCTACC/TTTCTG 1 -- ut310--------
    rs83951,2
    C,F,A,H--27715207(-) GGGTAA/TTGCCA 1 -- ut3117Minor allele frequency- T:0.35MN NA NS EA WA CSA 1232

    HapMap Linkage Disequilibrium report for FNDC4 (27714750 - 27718126 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for FNDC4:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv817684CNV Gain17921354

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing FNDC4
    DNA2.0 Custom Variant and Variant Library Synthesis for FNDC4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 611905    OMIM disorders: --

    1 disease for FNDC4:    About MalaCards
    kidney disease


    FNDC4 for disorders           About GeneDecksing

    Genetic Association Database (GAD): FNDC4
    Human Genome Epidemiology (HuGE) Navigator: FNDC4 (3 documents)

    Export disorders for FNDC4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for FNDC4 gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with FNDC4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. (PubMed id 22267201)1, 4 Stolk L....Lunetta K.L. (Nat. Genet. 2012)
    2. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W.... Wilson R.K. (Nature 2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    7. Frcp1 and Frcp2, two novel fibronectin type III repeat containing genes. (PubMed id 12384288)1, 3 Teufel A....Westphal H. (Gene 2002)
    8. Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci. (PubMed id 23505323)1 Weissglas-Volkov D....Pajukanta P. (J. Med. Genet. 2013)
    9. Discovery and fine mapping of serum protein loci through transethnic meta-analysis. (PubMed id 23022100)1 Franceschini N....Morris A.P. (Am. J. Hum. Genet. 2012)
    10. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 64838 HGNC: 20239 AceView: FNDC4 Ensembl:ENSG00000115226 euGenes: HUgn64838
    ECgene: FNDC4 H-InvDB: FNDC4

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for FNDC4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for FNDC4 gene:
    Search GeneIP for patents involving FNDC4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for FNDC4   OriGene RNAi products in human, mouse, rat for FNDC4  
     OriGene qPCR primer pairs and template standards for FNDC4   OriGene Protein Over-expression Lysate for FNDC4  
     OriGene MassSpec something-or-other for FNDC4   OriGene clones in human, mouse for FNDC4  
     OriGene qSTAR qPCR primer pairs in human, mouse for FNDC4   OriGene Purified Protein for FNDC4  
     OriGene ORF clones in mouse, rat for FNDC4   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for FNDC4   OriGene Custom Protein Services for FNDC4  

     
     
     Block miRNA regulation of human, mouse, rat FNDC4 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing FNDC4
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FNDC4 Predesigned siRNA for gene silencing in human, mouse, rat FNDC4
     QuantiFast Probe-based Assays in human, mouse, rat FNDC4 QuantiTect SYBR Green Assays in human, mouse, rat FNDC4
     Custom PCR Arrays for FNDC4 Search Chromatin IP Primers for FNDC4
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FNDC4  Search GeneGlobe Interaction Network for FNDC4
     Regulatory tfbs in FNDC4 promoter
     GenScript Custom Purified and Recombinant Proteins Services for FNDC4 GenScript cDNA clones with any tag delivered in your preferred vector for FNDC4
     GenScript Custom Assay Services for FNDC4 GenScript Custom overexpressing Cell Line Services for FNDC4
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for FNDC4
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for FNDC4
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     FNDC4 antibodies
     FNDC4 proteins
     FNDC4 lysates
     Antibodies for FNDC4
     See all of Abcam's Antibodies, Kits and Proteins for FNDC4
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for FNDC4
     Antibodies for FNDC4
     ELISAs for FNDC4
     CLIAs for FNDC4



     Browse ESI BIO Cell Lines and PureStem Progenitors for FNDC4
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FNDC4
     SwitchGear 3'UTR luciferase reporter plasmids for FNDC4
     SwitchGear Promoter luciferase reporter plasmids for FNDC4
     Search ThermoFisher Antibodies for FNDC4
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FNDC4
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FNDC4
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FNDC4
     LSBio Antibodies in human, mouse, rat for FNDC4
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      FNDC4 gene at Home site.
    Version: 3.12.136 22 July 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4