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Aliases for FNDC3A Gene

Aliases for FNDC3A Gene

  • Fibronectin Type III Domain Containing 3A 2 3
  • Human Gene Expressed In Odontoblasts 3 4
  • FNDC3 3 4
  • HUGO 3 4
  • Fibronectin Type-III Domain-Containing Protein 3A 3
  • Fibronectin Type III Domain Containing 3 2
  • BA203I16.1 3
  • BA203I16.5 3
  • KIAA0970 4

External Ids for FNDC3A Gene

Previous Symbols for FNDC3A Gene

  • FNDC3

Summaries for FNDC3A Gene

GeneCards Summary for FNDC3A Gene

FNDC3A (Fibronectin Type III Domain Containing 3A) is a Protein Coding gene. An important paralog of this gene is DSCAML1.

UniProtKB/Swiss-Prot for FNDC3A Gene

  • Mediates spermatid-Sertoli adhesion during spermatogenesis.

Gene Wiki entry for FNDC3A Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FNDC3A Gene

Genomics for FNDC3A Gene

Genomic Location for FNDC3A Gene

48,975,912 bp from pter
49,209,779 bp from pter
233,868 bases
Plus strand

Genomic View for FNDC3A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FNDC3A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FNDC3A Gene

Regulatory Elements for FNDC3A Gene

Proteins for FNDC3A Gene

  • Protein details for FNDC3A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Fibronectin type-III domain-containing protein 3A
    Protein Accession:
    Secondary Accessions:
    • B4DYG1
    • Q5HYC9
    • Q5JVF8
    • Q5JVF9
    • Q6EVH3
    • Q6EVH4
    • Q6N020
    • Q6P9D5
    • Q6ZME4
    • Q9H1W1

    Protein attributes for FNDC3A Gene

    1198 amino acids
    Molecular mass:
    131852 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA76814.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAD18784.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for FNDC3A Gene

    Alternative splice isoforms for FNDC3A Gene


neXtProt entry for FNDC3A Gene

Proteomics data for FNDC3A Gene at MOPED

Post-translational modifications for FNDC3A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FNDC3A Gene

No data available for DME Specific Peptides for FNDC3A Gene

Domains for FNDC3A Gene

Gene Families for FNDC3A Gene

  • FN3 :Fibronectin type III domain containing

Protein Domains for FNDC3A Gene


  • Contains 9 fibronectin type-III domains.:
    • Q9Y2H6
  • Belongs to the FNDC3 family.:
    • Q9Y2H6
genes like me logo Genes that share domains with FNDC3A: view

Function for FNDC3A Gene

Molecular function for FNDC3A Gene

UniProtKB/Swiss-Prot Function: Mediates spermatid-Sertoli adhesion during spermatogenesis.

Gene Ontology (GO) - Molecular Function for FNDC3A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with FNDC3A: view

Phenotypes for FNDC3A Gene

genes like me logo Genes that share phenotypes with FNDC3A: view

miRNA for FNDC3A Gene

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for FNDC3A Gene

Localization for FNDC3A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FNDC3A Gene

Golgi apparatus membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for FNDC3A Gene COMPARTMENTS Subcellular localization image for FNDC3A gene
Compartment Confidence
golgi apparatus 5
plasma membrane 3
cytosol 2
endoplasmic reticulum 2
extracellular 1
mitochondrion 1
nucleus 1

Gene Ontology (GO) - Cellular Components for FNDC3A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000139 Golgi membrane IEA --
GO:0001669 acrosomal vesicle IEA --
GO:0005794 Golgi apparatus IDA 18218838
GO:0005829 cytosol IEA --
GO:0012506 vesicle membrane IEA --
genes like me logo Genes that share ontologies with FNDC3A: view

Pathways for FNDC3A Gene

SuperPathways for FNDC3A Gene

No Data Available

Interacting Proteins for FNDC3A Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000417257 for FNDC3A Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for FNDC3A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007286 spermatid development IEA --
GO:0009566 fertilization IEA --
GO:0016337 single organismal cell-cell adhesion IEA --
GO:0060009 Sertoli cell development IEA --
genes like me logo Genes that share ontologies with FNDC3A: view

No data available for Pathways by source for FNDC3A Gene

Transcripts for FNDC3A Gene

Unigene Clusters for FNDC3A Gene

Fibronectin type III domain containing 3A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FNDC3A Gene

No ASD Table

Relevant External Links for FNDC3A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FNDC3A Gene

mRNA expression in normal human tissues for FNDC3A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FNDC3A Gene

SOURCE GeneReport for Unigene cluster for FNDC3A Gene Hs.508010

mRNA Expression by UniProt/SwissProt for FNDC3A Gene

Tissue specificity: Expressed in the odontoblast and nerves in the dental pulp. Also expressed in trachea and to a lesser extent in the brain, liver, lung and kidney.
genes like me logo Genes that share expressions with FNDC3A: view

Orthologs for FNDC3A Gene

This gene was present in the common ancestor of animals.

Orthologs for FNDC3A Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia FNDC3A 36
  • 99.81 (n)
  • 99.75 (a)
  • 100 (a)
(Bos Taurus)
Mammalia FNDC3A 36
  • 92.79 (n)
  • 94.24 (a)
  • 94 (a)
(Canis familiaris)
Mammalia FNDC3A 36
  • 93.91 (n)
  • 95.41 (a)
  • 94 (a)
(Mus musculus)
Mammalia Fndc3a 36
  • 88.45 (n)
  • 91.07 (a)
Fndc3a 16
Fndc3a 37
  • 91 (a)
(Monodelphis domestica)
Mammalia FNDC3A 37
  • 86 (a)
(Ornithorhynchus anatinus)
Mammalia FNDC3A 37
  • 86 (a)
(Rattus norvegicus)
Mammalia Fndc3a 36
  • 87.88 (n)
  • 90.89 (a)
(Gallus gallus)
Aves FNDC3A 36
  • 80.37 (n)
  • 80.03 (a)
  • 80 (a)
(Anolis carolinensis)
Reptilia FNDC3A 37
  • 56 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.21668 36
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100492173 36
  • 73.95 (n)
  • 73.64 (a)
Str.15243 36
(Danio rerio)
Actinopterygii FNDC3A 37
  • 52 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009522 36
  • 25.26 (n)
  • 9.96 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG42389 36
  • 44.57 (n)
  • 36.71 (a)
CG42389 37
  • 19 (a)
(Caenorhabditis elegans)
Secernentea let-805 37
  • 7 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 38 (a)
Species with no ortholog for FNDC3A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FNDC3A Gene

Gene Tree for FNDC3A (if available)
Gene Tree for FNDC3A (if available)

Paralogs for FNDC3A Gene

Paralogs for FNDC3A Gene

Selected SIMAP similar genes for FNDC3A Gene using alignment to 3 proteins: Pseudogenes for FNDC3A Gene

genes like me logo Genes that share paralogs with FNDC3A: view

Variants for FNDC3A Gene

Sequence variations from dbSNP and Humsavar for FNDC3A Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type MAF
rs8248 -- 48,975,435(+) GGGTT(C/G)GAAGT upstream-variant-2KB
rs716722 -- 49,178,942(+) GGCTG(A/G)TCTCA intron-variant
rs728075 -- 48,999,087(-) TGCTG(C/T)GGGGC intron-variant
rs736222 -- 49,202,204(+) ATAAT(G/T)TAGCA intron-variant
rs928039 -- 48,979,992(-) CAAGA(A/C)ATTTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FNDC3A Gene

Variant ID Type Subtype PubMed ID
nsv1034 CNV Loss 18451855
nsv455882 CNV Loss 19166990
dgv1585n71 CNV Loss 21882294
nsv1035 CNV Loss 18451855
nsv1036 CNV Insertion 18451855
nsv832607 CNV Loss 17160897

Relevant External Links for FNDC3A Gene

HapMap Linkage Disequilibrium report

Disorders for FNDC3A Gene

Relevant External Links for FNDC3A

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with FNDC3A: view

No data available for UniProtKB/Swiss-Prot for FNDC3A Gene

Publications for FNDC3A Gene

  1. HUGO (FNDC3A): a new gene overexpressed in human odontoblasts. (PMID: 18218838) Carrouel F. … Bleicher F. (J. Dent. Res. 2008) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A. … Ross M.T. (Nature 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4

Products for FNDC3A Gene

Sources for FNDC3A Gene

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