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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FNBP1L Gene

protein-coding   GIFtS: 53
GCID: GC01P093913

Formin Binding Protein 1-Like

(Previous name: chromosome 1 open reading frame 39)
(Previous symbol: C1orf39)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Formin Binding Protein 1-Like1 2     Formin-Binding Protein 1-Like2
C1orf391 2 3     toca-12
Transducer Of Cdc42-Dependent Actin Assembly Protein 12 3     Transducer Of Cdc42-Dependent Actin Assembly 12
TOCA12 3     Toca-13
Chromosome 1 Open Reading Frame 391     

External Ids:    HGNC: 208511   Entrez Gene: 548742   Ensembl: ENSG000001379427   OMIM: 6088485   UniProtKB: Q5T0N53   

Export aliases for FNBP1L gene to outside databases

Previous GC identifers: GC01P093626 GC01P093737 GC01P092035


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FNBP1L Gene:
The protein encoded by this gene binds to both CDC42 and N-WASP. This protein promotes CDC42-induced actin
polymerization by activating the N-WASP-WIP complex and, therefore, is involved in a pathway that links cell
surface signals to the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding
different isoforms. (provided by RefSeq, Jul 2008)

GeneCards Summary for FNBP1L Gene: 
FNBP1L (formin binding protein 1-like) is a protein-coding gene. Diseases associated with FNBP1L include neuronitis. GO annotations related to this gene include lipid binding and protein binding. An important paralog of this gene is TRIP10.

UniProtKB/Swiss-Prot: FBP1L_HUMAN, Q5T0N5
Function: Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during
endocytosis. May bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote
membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by
activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. Actin polymerization
may promote the fission of membrane tubules to form endocytic vesicles. Essential for autophagy of intracellular
bacterial pathogens

Gene Wiki entry for FNBP1L Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_032977.9  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FNBP1L gene promoter:
         STAT5B   ISGF-3   p53   Nkx2-2   Ik-3   SRY   POU2F1   POU2F1a   FOXJ2 (long isoform)   FOXJ2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFNBP1L promoter sequence
   Search SABiosciences Chromatin IP Primers for FNBP1L

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FNBP1L


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p22.1   Ensembl cytogenetic band:  1p22.1   HGNC cytogenetic band: 1p22.1

FNBP1L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FNBP1L gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P093913:  view genomic region     (about GC identifiers)

Start:
93,913,688 bp from pter      End:
94,020,218 bp from pter
Size:
106,531 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: FBP1L_HUMAN, Q5T0N5 (See protein sequence)
Recommended Name: Formin-binding protein 1-like  
Size: 605 amino acids; 69977 Da
Subunit: Homodimerizes, the dimers can polymerize end-to-end to form filamentous structures (By similarity).
Interacts with GTP-bound CDC42. Interacts with DAAM1, DIAPH1, DIAPH2, DNM1, DNM2 and WASL/N-WASP. Interacts with
ATG3
Subcellular location: Cytoplasm. Cytoplasm, cytoskeleton (By similarity). Cytoplasm, cell cortex (By similarity).
Cytoplasmic vesicle (By similarity). Cell membrane; Peripheral membrane protein; Cytoplasmic side (By similarity)
Sequence caution: Sequence=BAA91051.1; Type=Erroneous initiation; Sequence=CAI18954.1; Type=Erroneous gene model
prediction; Sequence=CAI18981.1; Type=Erroneous gene model prediction;
Secondary accessions: Q5T0N6 Q6B097 Q6P653 Q6R4Q4 Q9NXG1
Alternative splicing: 5 isoforms:  Q5T0N5-1   Q5T0N5-2   Q5T0N5-3   Q5T0N5-4   Q5T0N5-5   (Gene prediction based on EST data. No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FNBP1L: NX_Q5T0N5

Explore proteomics data for FNBP1L at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q5T0N5

  • FNBP1L Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    FNBP1L Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001020119.1  NP_001157945.1  NP_060207.2  

    ENSEMBL proteins: 
     ENSP00000473921   ENSP00000359275   ENSP00000397451   ENSP00000271234   ENSP00000359278  
     ENSP00000260506  

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    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005856cytoskeleton IEA--
    GO:0005886plasma membrane IEA--
    GO:0005938cell cortex IEA--
    GO:0016023cytoplasmic membrane-bounded vesicle IDA--

    FNBP1L for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR001060 FCH_dom
     IPR001452 SH3_domain

    Graphical View of Domain Structure for InterPro Entry Q5T0N5

    ProtoNet protein and cluster: Q5T0N5

    2 Blocks protein domains:
    IPB001060 Cdc15/Fes/CIP4
    IPB003016 2-oxo acid dehydrogenase


    UniProtKB/Swiss-Prot: FBP1L_HUMAN, Q5T0N5
    Domain: The F-BAR domain binds the phospholipid membrane with its concave surface. The end-to-end polymerization
    of dimers of these domains provides a curved surface that fits best membranes with around 600 A diameter, and may
    drive tubulation (By similarity)
    Similarity: Belongs to the FNBP1 family
    Similarity: Contains 1 FCH domain
    Similarity: Contains 1 REM (Hr1) repeat
    Similarity: Contains 1 SH3 domain


    FNBP1L for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FBP1L_HUMAN, Q5T0N5
    Function: Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during
    endocytosis. May bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote
    membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by
    activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. Actin polymerization
    may promote the fission of membrane tubules to form endocytic vesicles. Essential for autophagy of intracellular
    bacterial pathogens

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16630611
    GO:0008289lipid binding IEA--
         
    FNBP1L for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for FNBP1L:
     Decreased number of cells in m 

    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for FNBP1L

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/92 Interacting proteins for FNBP1L (Q5T0N51, 2, 3 ENSP000002712344) via UniProtKB, MINT, STRING, and/or I2D (see all 92)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DAAM1Q9Y4D11, 2, 3, ENSP000002471704EBI-714058,EBI-2817289 MINT-7146145 MINT-7146222 I2D: score=1 STRING: ENSP00000247170
    USP13Q929952, 3MINT-65085 I2D: score=5 
    SGSM2O431472, 3, ENSP000002689894MINT-64873 I2D: score=5 STRING: ENSP00000268989
    CDC42P609533, ENSP000003144584I2D: score=1 STRING: ENSP00000314458
    WASLO004013, ENSP000002230234I2D: score=1 STRING: ENSP00000223023
    About this table

    Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006900membrane budding IDA--
    GO:0006914autophagy IEA--
    GO:0007165signal transduction ----
    GO:0010324membrane invagination IDA--
    GO:0016050vesicle organization IDA--

    FNBP1L for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for FNBP1L (FBP1L)

    10/125 HMDB Compounds for FNBP1L (see all 125)    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--
    PS(14:0/14:0)Phosphatidylserine(14:0/14:0) (see all 7)----
    PS(14:0/14:1(9Z))Phosphatidylserine(14:0/14:1n5) (see all 13)----
    PS(14:0/16:0)1-myristoyl-2-palmitoyl-sn-glycero-3-phosphoserine (see all 7)----
    PS(14:0/16:1(9Z))PS(14:0/16:1n7) (see all 13)----
    PS(14:0/18:0)Phosphatidylserine(32:0) (see all 7)----
    PS(14:0/18:1(9Z))PSer(14:0/18:1n9) (see all 13)----
    PS(14:0/18:2(9Z,12Z))PS(14:0/18:2) (see all 13)----
    PS(14:0/18:3(9Z,12Z,15Z))Phosphatidylserine(14:0/18:3) (see all 14)----
    PS(14:0/20:3(8Z,11Z,14Z))PSer(14:0/20:3) (see all 14)----

    Search CenterWatch for drugs/clinical trials and news about FNBP1L / FBP1L

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for FNBP1L gene (3 alternative transcripts): 
    NM_001024948.2  NM_001164473.2  NM_017737.4  

    Unigene Cluster for FNBP1L:

    Formin binding protein 1-like
    Hs.134060  [show with all ESTs]
    Unigene Representative Sequence: NM_001024948
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000604705 ENST00000370253 ENST00000424449 ENST00000603526 ENST00000271234(uc010otk.2)
    ENST00000370256(uc001dpv.3 uc010otl.2) ENST00000260506(uc001dpw.3)

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    Additional mRNA sequence: 

    AK000282.1 AK025526.1 AK026988.1 AK296767.1 AK299760.1 AK299943.1 AK315981.1 AY514449.1 
    BC062477.1 BC074891.2 BC074892.2 

    9 DOTS entries:

    DT.451610  DT.100752116  DT.99982744  DT.121365406  DT.40132926  DT.97785346  DT.95214915  DT.121365381 
    DT.99990332 

    24/202 AceView cDNA sequences (see all 202):

    AA411745 AI812007 BC062477 BG261286 AI142290 CK430000 D58132 BX418915 
    AK000282 NM_017737 CD106648 AA135779 AI024012 AW190720 Z46021 BQ573837 
    AI333211 AI949924 BF434949 F03922 AI683218 AU279598 BI916518 BG610667 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FNBP1L expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    FNBP1L Expression
    About this image


    See FNBP1L Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FNBP1L

    SOURCE GeneReport for Unigene cluster: Hs.134060
        SABiosciences Expression via Pathway-Focused PCR Array including FNBP1L: 
              Cytoskeleton Regulators in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for FNBP1L gene from 8/20 species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fnbp1l1 , 5 formin binding protein 1-like1, 5 92.38(n)1
    98(a)1
      3 (53.63 cM)5
    2144591  NM_153118.21  NP_694758.21 
     1225387195 
    chicken
    (Gallus gallus)
    Aves FNBP1L6
    formin binding protein 1-like
    93(a)
    1 ↔ 1
    8(12812439-12843013)
    lizard
    (Anolis carolinensis)
    Reptilia FNBP1L6
    formin binding protein 1-like
    89(a)
    1 ↔ 1
    4(88347813-88398544)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.338872 Xenopus laevis transcribed sequence with moderate similarity more 78.03(n)    BJ617609.1 
    zebrafish
    (Danio rerio)
    Actinopterygii CK030078.12   -- 75.75(n)    CK030078.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Cip41 CG15015-PA 48.5(n)
    41.17(a)
      38534  NM_139636.3  NP_647893.2 
    worm
    (Caenorhabditis elegans)
    Secernentea toca-16
    toca-26
    Protein TOCA-2, isoform b
    26(a)
    20(a)
    many ↔ many
    many ↔ many
    X(1511068-1521487)
    III(13755942-13759451)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes BZZ11 Bzz1p 39.2(n)
    21.8(a)
      856514   NP_011982.1 


    ENSEMBL Gene Tree for FNBP1L (if available)
    TreeFam Gene Tree for FNBP1L (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FNBP1L gene
    TRIP102  FNBP12  
    4 SIMAP similar genes for FNBP1L using alignment to 2 protein entries:     FBP1L_HUMAN (see all proteins):
    FNBP1    TRIP10    STP    NCKIPSD

    FNBP1L for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1814 SNPs in FNBP1L are shown (see all 1814)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1883428881,2
    --93911863(+) CTTGAG/TATCAG 3 -- us2k10--------
    rs1496916061,2
    --93911892(+) GCCAAC/TATGGT 3 -- us2k10--------
    rs1170542281,2
    F--93911911(+) ATCTCC/TACTAA 3 -- us2k11Minor allele frequency- T:0.02EA 120
    rs1912361281,2
    --93911922(+) AAACAC/TAAAAT 3 -- us2k10--------
    rs75419841,2
    C,F,A--93911952(+) ggcgcA/Ctgtaa 3 -- us2k16Minor allele frequency- C:0.40NA WA CSA 10
    rs1488791841,2
    C--93911984(+) AGGCAA/GGAGAA 3 -- us2k10--------
    rs171099541,2
    C,F,H--93912195(+) AGGTGA/TCATAA 3 -- us2k112Minor allele frequency- T:0.10NA NS EA WA 684
    rs1838267981,2
    --93912255(+) AAAGTA/GTTGTT 3 -- us2k10--------
    rs171099581,2
    C,F,H--93912290(+) CATGGT/CACAAA 3 -- us2k113Minor allele frequency- C:0.17NA EA NS WA 998
    rs1454153141,2
    C--93912303(+) TAAGCA/GTTTAA 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for FNBP1L (93913688 - 94020218 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for FNBP1L:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv871640CNV Loss21882294

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 608848    OMIM disorders: --

    2 diseases for FNBP1L:    About MalaCards
    neuronitis    


    FNBP1L for disorders           About GeneDecksing

    Genetic Association Database (GAD): FNBP1L
    Human Genome Epidemiology (HuGE) Navigator: FNBP1L (1 document)

    Export disorders for FNBP1L gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FNBP1L gene, integrated from 9 sources (see all 34):
    (articles sorted by number of sources associating them with FNBP1L)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of human FNBP1L gene in silico. (PubMed id 14654988)1, 3, 9 Katoh M. and Katoh M. (2004)
    2. A novel hybrid yeast-human network analysis reveals an essential role for FNBP1L in antibacterial autophagy. (PubMed id 19342671)1, 2, 9 Huett A....Xavier R.J. (2009)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    4. The diaphanous-related formin DAAM1 collaborates with the Rho GTPases RhoA and Cdc42, CIP4 and Src in regulating cell morphogenesis and actin dynamics. (PubMed id 16630611)1, 2 Aspenstroem P.... Johansson A.-S. (2006)
    5. Tuba stimulates intracellular N-WASP-dependent actin assembly. (PubMed id 16757518)1, 2 Kovacs E.M.... Gertler F.B. (2006)
    6. Coordination between the actin cytoskeleton and membrane deformation by a novel membrane tubulation domain of PCH proteins is involved in endocytosis. (PubMed id 16418535)1, 2 Tsujita K....Takenawa T. (2006)
    7. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    8. Dynamin and the actin cytoskeleton cooperatively regulate plasma membrane invagination by BAR and F-BAR proteins. (PubMed id 16326391)1, 2 Itoh T....De Camilli P. (2005)
    9. Toca-1 mediates Cdc42-dependent actin nucleation by activating the N- WASP-WIP complex. (PubMed id 15260990)1, 2 Ho H.-Y.H....Kirschner M.W. (2004)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 54874 HGNC: 20851 AceView: C1orf39 Ensembl:ENSG00000137942 euGenes: HUgn54874
    ECgene: FNBP1L H-InvDB: FNBP1L

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FNBP1L Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for FNBP1L gene:
    Search GeneIP for patents involving FNBP1L

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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