Free for academic non-profit institutions. Other users need a Commercial license

Aliases for FMR1NB Gene

Aliases for FMR1NB Gene

  • Fragile X Mental Retardation 1 Neighbor 2 3
  • Cancer/Testis Antigen 37 2 3 4
  • Sarcoma Antigen NY-SAR-35 3 4
  • CT37 3 4
  • Fragile X Mental Retardation 1 Neighbor Protein 3
  • NY-SAR-35 3
  • NYSAR35 3

External Ids for FMR1NB Gene

Previous GeneCards Identifiers for FMR1NB Gene

  • GC00U914342
  • GC0XP145731
  • GC0XP146768
  • GC0XP146870
  • GC0XP147062
  • GC0XP136023

Summaries for FMR1NB Gene

GeneCards Summary for FMR1NB Gene

FMR1NB (Fragile X Mental Retardation 1 Neighbor) is a Protein Coding gene. Diseases associated with FMR1NB include sarcoma.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FMR1NB Gene

Genomics for FMR1NB Gene

Genomic Location for FMR1NB Gene

147,981,329 bp from pter
148,026,667 bp from pter
45,339 bases
Plus strand

Genomic View for FMR1NB Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FMR1NB Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FMR1NB Gene

No data available for Regulatory Elements for FMR1NB Gene

Proteins for FMR1NB Gene

  • Protein details for FMR1NB Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Fragile X mental retardation 1 neighbor protein
    Protein Accession:
    Secondary Accessions:
    • D3DWT3

    Protein attributes for FMR1NB Gene

    255 amino acids
    Molecular mass:
    29241 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FMR1NB Gene

Proteomics data for FMR1NB Gene at MOPED

Post-translational modifications for FMR1NB Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FMR1NB Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

  • Santa Cruz Biotechnology (SCBT) Antibodies for FMR1NB

No data available for DME Specific Peptides for FMR1NB Gene

Domains for FMR1NB Gene

Protein Domains for FMR1NB Gene


Suggested Antigen Peptide Sequences for FMR1NB Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 P-type (trefoil) domain.
  • Contains 1 P-type (trefoil) domain.
genes like me logo Genes that share domains with FMR1NB: view

No data available for Gene Families for FMR1NB Gene

Function for FMR1NB Gene

Phenotypes for FMR1NB Gene

GenomeRNAi human phenotypes for FMR1NB:
genes like me logo Genes that share phenotypes with FMR1NB: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FMR1NB

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FMR1NB Gene

Localization for FMR1NB Gene

Subcellular locations from UniProtKB/Swiss-Prot for FMR1NB Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for FMR1NB Gene COMPARTMENTS Subcellular localization image for FMR1NB gene
Compartment Confidence
nucleus 4
plasma membrane 3
mitochondrion 1

Gene Ontology (GO) - Cellular Components for FMR1NB Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IDA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with FMR1NB: view

Pathways for FMR1NB Gene

SuperPathways for FMR1NB Gene

No Data Available

Interacting Proteins for FMR1NB Gene

Gene Ontology (GO) - Biological Process for FMR1NB Gene


No data available for Pathways by source for FMR1NB Gene

Transcripts for FMR1NB Gene

mRNA/cDNA for FMR1NB Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(11) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FMR1NB Gene

Fragile X mental retardation 1 neighbor:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FMR1NB

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FMR1NB Gene

No ASD Table

Relevant External Links for FMR1NB Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FMR1NB Gene

mRNA expression in normal human tissues for FMR1NB Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FMR1NB Gene

This gene is overexpressed in Testis (51.5).

Protein differential expression in normal tissues for FMR1NB Gene

This gene is overexpressed in Testis (51.9) and Ovary (17.1).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for FMR1NB Gene

SOURCE GeneReport for Unigene cluster for FMR1NB Gene Hs.128580

mRNA Expression by UniProt/SwissProt for FMR1NB Gene

Tissue specificity: Testis-specific. Expressed in melanoma, sarcoma, lung, breast, bladder, esophageal and ovarian cancers.
genes like me logo Genes that share expressions with FMR1NB: view

Expression partners for FMR1NB Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

Orthologs for FMR1NB Gene

This gene was present in the common ancestor of chordates.

Orthologs for FMR1NB Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FMR1NB 35
  • 69.68 (n)
  • 52.41 (a)
  • 40 (a)
(Canis familiaris)
Mammalia FMR1NB 35
  • 68.67 (n)
  • 48.8 (a)
  • 43 (a)
(Pan troglodytes)
Mammalia FMR1NB 35
  • 96.19 (n)
  • 92.13 (a)
  • 92 (a)
(Mus musculus)
Mammalia Fmr1nb 16
Fmr1nb 36
  • 35 (a)
(Monodelphis domestica)
Mammalia FMR1NB 36
  • 20 (a)
(Ornithorhynchus anatinus)
Mammalia FMR1NB 36
  • 25 (a)
(Gallus gallus)
Aves FMR1NB 35
  • 50.71 (n)
  • 36.43 (a)
  • 31 (a)
Species with no ortholog for FMR1NB:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FMR1NB Gene

Gene Tree for FMR1NB (if available)
Gene Tree for FMR1NB (if available)

Paralogs for FMR1NB Gene

No data available for Paralogs for FMR1NB Gene

Variants for FMR1NB Gene

Sequence variations from dbSNP and Humsavar for FMR1NB Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs215110 -- 148,025,157(-) AATAT(G/T)TGTTC intron-variant
rs215111 -- 148,025,994(-) CACTT(A/C/G/T)TCCTA intron-variant
rs215112 -- 148,026,792(+) TCAAC(A/G)TATAC downstream-variant-500B
rs426718 -- 148,026,057(-) GTATC(A/C)CATAT intron-variant
rs426719 -- 148,026,056(-) TATCC(A/C)ATATA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FMR1NB Gene

Variant ID Type Subtype PubMed ID
dgv2489e1 CNV Complex 17122850
nsv513626 CNV Insertion 21212237
esv2740586 CNV Deletion 23290073
esv2122565 CNV Deletion 18987734
esv2741031 CNV Deletion 23290073

Relevant External Links for FMR1NB Gene

HapMap Linkage Disequilibrium report
Locus Specific Mutation Databases (LSDB)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FMR1NB Gene

Disorders for FMR1NB Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for FMR1NB Gene in MalaCards »

(1) Disease for FMR1NB Gene

(1) University of Copenhagen DISEASES for FMR1NB Gene

genes like me logo Genes that share disorders with FMR1NB: view

No data available for OMIM , UniProtKB/Swiss-Prot , Novoseek inferred disease relationships , Genatlas and External Links for FMR1NB Gene

Publications for FMR1NB Gene

  1. Immunomic analysis of human sarcoma. (PMID: 12601173) Lee S.-Y. … Scanlan M.J. (Proc. Natl. Acad. Sci. U.S.A. 2003) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for FMR1NB Gene

Sources for FMR1NB Gene

Back to Top