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Aliases for FMR1NB Gene

Aliases for FMR1NB Gene

  • FMR1 Neighbor 2 3
  • Cancer/Testis Antigen 37 2 3 4
  • Fragile X Mental Retardation 1 Neighbor 2 5
  • Sarcoma Antigen NY-SAR-35 3 4
  • CT37 3 4
  • Fragile X Mental Retardation 1 Neighbor Protein 3
  • NY-SAR-35 3
  • NYSAR35 3

External Ids for FMR1NB Gene

Previous GeneCards Identifiers for FMR1NB Gene

  • GC00U914342
  • GC0XP145731
  • GC0XP146768
  • GC0XP146870
  • GC0XP147062
  • GC0XP136023

Summaries for FMR1NB Gene

GeneCards Summary for FMR1NB Gene

FMR1NB (FMR1 Neighbor) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FMR1NB Gene

Genomics for FMR1NB Gene

Genomic Location for FMR1NB Gene

147,981,329 bp from pter
148,026,667 bp from pter
45,339 bases
Plus strand

Genomic View for FMR1NB Gene

Genes around FMR1NB on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FMR1NB Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FMR1NB Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FMR1NB Gene

No data available for Regulatory Elements for FMR1NB Gene

Proteins for FMR1NB Gene

  • Protein details for FMR1NB Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Fragile X mental retardation 1 neighbor protein
    Protein Accession:
    Secondary Accessions:
    • D3DWT3

    Protein attributes for FMR1NB Gene

    255 amino acids
    Molecular mass:
    29241 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FMR1NB Gene

Post-translational modifications for FMR1NB Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FMR1NB Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FMR1NB Gene

Domains & Families for FMR1NB Gene

Protein Domains for FMR1NB Gene


Suggested Antigen Peptide Sequences for FMR1NB Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with FMR1NB: view

No data available for Gene Families and UniProtKB/Swiss-Prot for FMR1NB Gene

Function for FMR1NB Gene

genes like me logo Genes that share phenotypes with FMR1NB: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FMR1NB Gene

Localization for FMR1NB Gene

Subcellular locations from UniProtKB/Swiss-Prot for FMR1NB Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FMR1NB gene
Compartment Confidence
plasma membrane 3
nucleus 3
mitochondrion 1

Gene Ontology (GO) - Cellular Components for FMR1NB Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with FMR1NB: view

Pathways & Interactions for FMR1NB Gene

SuperPathways for FMR1NB Gene

No Data Available

Gene Ontology (GO) - Biological Process for FMR1NB Gene


No data available for Pathways by source and SIGNOR curated interactions for FMR1NB Gene

Drugs & Compounds for FMR1NB Gene

No Compound Related Data Available

Transcripts for FMR1NB Gene

mRNA/cDNA for FMR1NB Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(11) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FMR1NB Gene

Fragile X mental retardation 1 neighbor:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for FMR1NB Gene

No ASD Table

Relevant External Links for FMR1NB Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FMR1NB Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FMR1NB Gene

mRNA differential expression in normal tissues according to GTEx for FMR1NB Gene

This gene is overexpressed in Testis (x51.5).

Protein differential expression in normal tissues from HIPED for FMR1NB Gene

This gene is overexpressed in Testis (51.9) and Ovary (17.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for FMR1NB Gene

Protein tissue co-expression partners for FMR1NB Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of FMR1NB Gene:


SOURCE GeneReport for Unigene cluster for FMR1NB Gene:


mRNA Expression by UniProt/SwissProt for FMR1NB Gene:

Tissue specificity: Testis-specific. Expressed in melanoma, sarcoma, lung, breast, bladder, esophageal and ovarian cancers.
genes like me logo Genes that share expression patterns with FMR1NB: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FMR1NB Gene

Orthologs for FMR1NB Gene

This gene was present in the common ancestor of chordates.

Orthologs for FMR1NB Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia FMR1NB 35 34
  • 96.19 (n)
(Bos Taurus)
Mammalia FMR1NB 35 34
  • 69.68 (n)
(Canis familiaris)
Mammalia FMR1NB 35 34
  • 68.67 (n)
(Mus musculus)
Mammalia Fmr1nb 35
  • 35 (a)
(Ornithorhynchus anatinus)
Mammalia FMR1NB 35
  • 25 (a)
(Monodelphis domestica)
Mammalia FMR1NB 35
  • 20 (a)
(Gallus gallus)
Aves FMR1NB 35 34
  • 50.71 (n)
Species where no ortholog for FMR1NB was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FMR1NB Gene

Gene Tree for FMR1NB (if available)
Gene Tree for FMR1NB (if available)

Paralogs for FMR1NB Gene

No data available for Paralogs for FMR1NB Gene

Variants for FMR1NB Gene

Sequence variations from dbSNP and Humsavar for FMR1NB Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs1000097576 -- 148,005,110(+) GTCTC(A/G)ATCTC intron-variant
rs1000166641 -- 148,003,420(+) AGTGG(A/G)ACAGA intron-variant
rs1000213452 -- 147,988,336(+) TTGGC(C/T)CCACT intron-variant
rs1000270253 -- 147,996,691(+) CAAGC(A/T)TGGAG intron-variant
rs1000303134 -- 147,980,725(+) TGTCC(A/G)GGATG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for FMR1NB Gene

Variant ID Type Subtype PubMed ID
dgv2508e212 CNV loss 25503493
esv2122565 CNV deletion 18987734
esv2740586 CNV deletion 23290073
esv2741031 CNV deletion 23290073
esv2758899 CNV gain 17122850
esv3574919 CNV loss 25503493
nsv513626 CNV insertion 21212237

Variation tolerance for FMR1NB Gene

Residual Variation Intolerance Score: 28.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.83; 58.60% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FMR1NB Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FMR1NB Gene

Disorders for FMR1NB Gene

Relevant External Links for FMR1NB

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FMR1NB Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FMR1NB Gene

Publications for FMR1NB Gene

  1. Immunomic analysis of human sarcoma. (PMID: 12601173) Lee S.-Y. … Scanlan M.J. (Proc. Natl. Acad. Sci. U.S.A. 2003) 2 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. Cancer/testis antigen NY-SAR-35 enhances cell proliferation, migration, and invasion. (PMID: 26648093) Song M.H. … Lee S.Y. (Int. J. Oncol. 2016) 3 64
  5. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64

Products for FMR1NB Gene

Sources for FMR1NB Gene

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