Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



FMO6P Gene

pseudogene   GIFtS: 43
GCID: GC01P171106

Flavin Containing Monooxygenase 6 Pseudogene

(Previous name: flavin containing monooxygenase 6)
(Previous symbol: FMO6)
  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Flavin Containing Monooxygenase 6 Pseudogene1 2     Dimethylaniline Oxidase 63
FMO61 2 3     Flavin-Containing Monooxygenase 63
EC 1.14.13.83 8     FMO 63
Flavin Containing Monooxygenase 61     

External Ids:    HGNC: 240241   Entrez Gene: 3887142   Ensembl: ENSG000001175077   UniProtKB: O607743   

Export aliases for FMO6P gene to outside databases

Previous GC identifers: GC01P169375 GC01P142330


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for FMO6P Gene:
FMO6P (flavin containing monooxygenase 6 pseudogene) is a pseudogene. An important paralog of this gene is FMO2.

UniProtKB/Swiss-Prot: FMO6_HUMAN, O60774
Function: It is probable that this protein is only produced in very small quantity or not at all as the gene
coding for it seems to be unable to produce full length transcripts




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_004487.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the FMO6P gene promoter:
         p53   NF-YA   CBF-C   CBF-A   CBF-B   HSF2   CP1A   CP1C   NF-Y   CBF(2)   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for FMO6P

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FMO6P


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q24.3   Ensembl cytogenetic band:  1q24.3   HGNC cytogenetic band: 1q24.3

FMO6P Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FMO6P gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P171106:  view genomic region     (about GC identifiers)

Start:
171,106,879 bp from pter      End:
171,130,707 bp from pter
Size:
23,829 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: FMO6_HUMAN, O60774 (See protein sequence)
Recommended Name: Putative dimethylaniline monooxygenase [N-oxide-forming] 6  
Size: 539 amino acids; 61291 Da
Cofactor: FAD (By similarity)
Caution: Could be the product of a pseudogene

Explore the universe of human proteins at neXtProt for FMO6P: NX_O60774

Explore proteomics data for FMO6P at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for FMO6P (O60774) (see all 17)
     EFTETSA  CFERSDD  SKEMMCF  EVYFGPC 


    See FMO6P Protein Expression from SPIRE MOPED, PaxDB, and MaxQB


    ENSEMBL proteins: 
     ENSP00000356728   ENSP00000236166  

    FMO6P Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for FMO6P
    GenScript Custom Purified and Recombinant Proteins Services for FMO6P
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for FMO6P 

     
    Search antibodies-online for proteins for FMO6P 

     
    Search antibodies-online for peptides for FMO6P

    FMO6P Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for FMO6P
    Search for Antibodies for FMO6P at Abcam
    Browse Antibodies at Cloud-Clone Corp.
    Search ThermoFisher Antibodies for FMO6P
    Search LSBio for Antibodies for FMO6P
    Search antibodies-online for antibodies for FMO6P 

    FMO6P Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for FMO6P
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for FMO6P
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for FMO6P 
    Search antibodies-online for kits for FMO6P 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    5 InterPro protein domains:
     IPR020946 Flavin_mOase-like
     IPR012143 DiMe-aniline_mOase
     IPR002255 Flavin_mOase_3
     IPR000960 Flavin_mOase
     IPR016040 NAD(P)-bd_dom

    Graphical View of Domain Structure for InterPro Entry O60774

    ProtoNet protein and cluster: O60774

    4 Blocks protein domains:
    IPB000759 Adrenodoxin reductase family signature
    IPB000960 Flavin-containing monooxygenase (FMO) signature
    IPB001327 Pyridine nucleotide-disulphide oxidoreductase
    IPB002255 Flavin-containing monooxygenase (FMO) 3 signature


    UniProtKB/Swiss-Prot: FMO6_HUMAN, O60774
    Similarity: Belongs to the FMO family


    Find genes that share domains with FMO6P           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FMO6_HUMAN, O60774
    Function: It is probable that this protein is only produced in very small quantity or not at all as the gene
    coding for it seems to be unable to produce full length transcripts
    Catalytic activity: N,N-dimethylaniline + NADPH + O(2) = N,N-dimethylaniline N-oxide + NADP(+) + H(2)O

         Enzyme Number (IUBMB): EC 1.14.13.81 2

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004499N,N-dimethylaniline monooxygenase activity ----
    GO:0016491oxidoreductase activity ----
    GO:0050660flavin adenine dinucleotide binding ----
    GO:0050661NADP binding ----
         
    Find genes that share ontologies with FMO6P           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FMO6P
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FMO6P

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FMO6P
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FMO6P

    miRNA
    Products:
        
    miRTarBase miRNAs that target FMO6P:
    hsa-mir-335-5p (MIRT017865)

    Block miRNA regulation of human, mouse, rat FMO6P using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate FMO6P
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for FMO6P
    Predesigned siRNA for gene silencing in human, mouse, rat FMO6P

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for FMO6P

    Clone
    Products:
         
    OriGene clones in human, mouse for FMO6P
    OriGene ORF clones in mouse, rat for FMO6P
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for FMO6P
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FMO6P
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FMO6P

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for FMO6P
    Browse ESI BIO Cell Lines and PureStem Progenitors for FMO6P 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FMO6P


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    FMO6_HUMAN, O60774: Microsome membrane (By similarity). Endoplasmic reticulum membrane (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum2
    peroxisome2
    plasma membrane2
    lysosome1
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005789endoplasmic reticulum membrane ----
    GO:0016021integral component of membrane ----

    Find genes that share ontologies with FMO6P           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FMO6P
    Interactions:

        Search GeneGlobe Interaction Network for FMO6P

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    Selected Interacting proteins for FMO6P (O607743 ENSP000002361664) via UniProtKB, MINT, STRING, and/or I2D (see all 23)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EDEM1Q926113, ENSP000002564974I2D: score=1 STRING: ENSP00000256497
    HSP90AA1P079003I2D: score=3 
    AADATQ8N5Z03I2D: score=1 
    CBSP355203I2D: score=1 
    CTHP329293I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0055114oxidation-reduction process ----

    Find genes that share ontologies with FMO6P           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FMO6P (FMO6)

    5 HMDB Compounds for FMO6P    About this table
    CompoundSynonyms CAS #PubMed Ids
    Dimethylaniline-N-oxideDimethylaniline N-oxide (see all 4)874-52-2--
    FAD1H-Purin-6-amine flavin dinucleotide (see all 21)146-14-5--
    N,N-DimethylanilineDimethylaminobenzene (see all 9)121-69-7--
    NADPAdenine-nicotinamide dinucleotide phosphate (see all 18)53-59-8--
    NADPH2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) Adenosine 5'-ester with 1,4-dihydro-1-b-D-ribofuranosylnicotinamide (see all 23)53-57-6--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    Unigene Cluster for FMO6P:

    Flavin containing monooxygenase 6 pseudogene
    Hs.448988  [show with all ESTs]
    Unigene Representative Sequence: AK130511
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000367754(uc001ghj.1) ENST00000236166
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat FMO6P using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate FMO6P
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for FMO6P
    Predesigned siRNA for gene silencing in human, mouse, rat FMO6P
    Clone
    Products:
         
    OriGene clones in human, mouse for FMO6P
    OriGene ORF clones in mouse, rat for FMO6P
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for FMO6P
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FMO6P
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FMO6P
    Primer
    Products:
        
    Browse OriGene qPCR
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat FMO6P
      QuantiTect SYBR Green Assays in human, mouse, rat FMO6P
      QuantiFast Probe-based Assays in human, mouse, rat FMO6P

    Additional mRNA sequence: 

    AK130511.1 NR_002601.1 

    2 DOTS entries:

    DT.75112621  DT.121330956 

    9 AceView cDNA sequences:

    AK130511 BX282694 CB853631 CA944858 AI978664 AI904089 AI904082 BU684072 
    AW369695 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    FMO6P expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    FMO6P Expression
    About this image

    FMO6P Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FMO6P Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.448988
        Custom PCR Arrays for FMO6P
    Primer
    Products:
    Browse OriGene qPCR
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat FMO6P
    QuantiTect SYBR Green Assays in human, mouse, rat FMO6P
    QuantiFast Probe-based Assays in human, mouse, rat FMO6P
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FMO6P

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for FMO6P gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fmo65 flavin containing monooxygenase 6   --   1 (70.34 cM) 162916551 
    chicken
    (Gallus gallus)
    Aves FMO36
    Gallus gallus flavin containing monooxygenase 6 ps...
    50(a)
    1 → many
    8(4792393-4800086)
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Dimethylaniline monooxygenase [N-oxide-forming]
    72(a)
    56(a)
    many ↔ many
    many ↔ many
    AAWZ02037914(2376-13155)
    GL343300.1(1575512-1596183)


    ENSEMBL Gene Tree for FMO6P (if available)
    TreeFam Gene Tree for FMO6P (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for FMO6P gene
    FMO22  FMO42  FMO32  FMO52  FMO12  
    6 SIMAP similar genes for FMO6P using alignment to 2 protein entries:     FMO6_HUMAN (see all proteins):
    FMO3    FMO5    DKFZp667E137    FMO2    FMO1    FMO4

    Find genes that share paralogs with FMO6P           About GenesLikeMe


    3 Pseudogenes.org Pseudogenes for FMO6P
    PGOHUM00000245064 PGOHUM00000258103 PGOHUM00000258104


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Polymorphic Variants from UniProtKB/Swiss-Prot
    FMO6_HUMAN, O60774: There are two alleles; one major, FMO6X105 (truncated form) and one minor, FMO6Q105, (shown here)
    (full-length form similar to the protein found in other mammals). A nonsense mutation transforms the Gln-105 into
    a premature stop codon. The truncated protein is catalytically inactive


    Selected SNPs for FMO6P (see all 528)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1411883901,2
    --171104930(+) GAATTA/GTCCCA 1 -- us2k10--------
    rs19201511,2
    C,F,O--171104943(-) TGGCTG/ATATAT 1 -- us2k111Minor allele frequency- A:0.30NA WA CSA EA 510
    rs730286491,2
    C,F--171105016(+) TTATAA/GGAAGA 1 -- us2k13Minor allele frequency- G:0.23WA CSA 122
    rs1806850981,2
    --171105050(+) CATACA/GTATTA 1 -- us2k10--------
    rs175653361,2
    C,F,H--171105089(+) TTCTAA/GGACTC 1 -- us2k121Minor allele frequency- G:0.12NA NS EA 2368
    rs1858855111,2
    --171105140(+) AGACAA/GACATC 1 -- us2k10--------
    rs1507485361,2
    C--171105266(+) CCCCAA/GTTTGT 1 -- us2k10--------
    rs168640941,2
    C,F,H--171105390(+) TTTGAC/ACTTTT 1 -- us2k1 tfbs319Minor allele frequency- A:0.10NA NS EA WA 2480
    rs1143178471,2
    C--171105405(+) GCACCG/TAATTC 1 -- us2k10--------
    rs1902150991,2
    --171105440(+) GATATA/GTAGTG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for FMO6P (171106879 - 171130707 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for FMO6P:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv28731CNV Gain+Loss19812545

    Human Gene Mutation Database (HGMD): FMO6P
    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing FMO6P
    DNA2.0 Custom Variant and Variant Library Synthesis for FMO6P

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus

    Find genes that share disorders with FMO6P           About GenesLikeMe

    Genetic Association Database (GAD): FMO6P
    Human Genome Epidemiology (HuGE) Navigator: FMO6P (2 documents)

    Export disorders for FMO6P gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for FMO6P gene integrated from 10 sources:
    (articles sorted by number of sources associating them with FMO6P)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Organization and evolution of the flavin-containing monooxygenase genes of human and mouse: identification of novel gene and pseudogene clusters. (PubMed id 15077013)1, 3, 9 Hernandez D....Shephard E.A. (Pharmacogenetics 2004)
    2. Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy. (PubMed id 19898482)1, 4 Ross C.J....Hayden M.R. (Nat. Genet. 2009)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    4. Identification of novel variants of the flavin-containing monooxygenase gene family in African Americans. (PubMed id 12527699)1, 2 Furnes B.... Schlenk D. (Drug Metab. Dispos. 2003)
    5. Alternative processing of the human FMO6 gene renders transcripts incapable of encoding a functional flavin-containing monooxygenase. (PubMed id 12130684)1, 2 Hines R.N.... Begun F.P. (Mol. Pharmacol. 2002)
    6. Genome-wide association identifies genetic variants associated with lentiform nucleus volume in Na88=a881345 young and elderly subjects. (PubMed id 22903471)1 Hibar D.P....Thompson P.M. (Brain Imaging Behav 2013)
    7. Single-nucleotide polymorphisms, acute rejection, and severity of tubulitis in kidney transplantation, accounting for center-to-center variation. (PubMed id 21085059)4 Israni A....Oetting W.S. (Transplantation 2010)
    8. Osmotic regulation of a novel flavin-containing monooxygenase in primary cultured cells from rainbow trout (Oncorhynchus mykiss). (PubMed id 18372402)9 RodrA-guez-Fuentes G....Schlenk D. (Drug Metab. Dispos. 2008)
    9. A novel flavin-containing monooxygenase from Methylophaga sp strain SK1 and its indigo synthesis in Escherichia coli. (PubMed id 12821131)9 Choi H.S....Kim S.W. (Biochem. Biophys. Res. Commun. 2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 388714 HGNC: 24024 AceView: LOC388714 Ensembl:ENSG00000117507 euGenes: HUgn388714
    ECgene: FMO6P H-InvDB: FMO6P

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for FMO6P Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for FMO6P gene:
    Search GeneIP for patents involving FMO6P

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for FMO6P  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for FMO6P  
     Browse OriGene qSTAR qPCR primer pairs   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for FMO6P   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for FMO6P   OriGene Custom Protein Services for FMO6P  

     
     
     Block miRNA regulation of human, mouse, rat FMO6P using miScript Target Protectors SeqTarget long-range PCR primers for resequencing FMO6P
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FMO6P Predesigned siRNA for gene silencing in human, mouse, rat FMO6P
     QuantiFast Probe-based Assays in human, mouse, rat FMO6P QuantiTect SYBR Green Assays in human, mouse, rat FMO6P
     Custom PCR Arrays for FMO6P Search Chromatin IP Primers for FMO6P
     Pre-validated RT2 qPCR Primer Assay in human, mouse / rat FMO6P  Search GeneGlobe Interaction Network for FMO6P
     Regulatory tfbs in FMO6P promoter
     GenScript Custom Purified and Recombinant Proteins Services for FMO6P GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for FMO6P
     GenScript Custom Assay Services for FMO6P GenScript Custom overexpressing Cell Line Services for FMO6P
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for FMO6P (FMO6)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Biologicals
     Novus Tissue Slides
     Search for Antibodies for FMO6P at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for FMO6P
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for FMO6P
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FMO6P
     Browse SwitchGear 3'UTR luciferase reporter plasmids for FMO6P
     Browse SwitchGear Promoter luciferase reporter plasmids for FMO6P
     Search ThermoFisher Antibodies for FMO6P
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FMO6P
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FMO6P
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FMO6P
     Search LSBio for Antibodies for FMO6P
     Browse compounds at ApexBio
     Search Addgene for plasmids for FMO6P
      Search eBioscience for proteins for FMO6P
      Search eBioscience for elisas for FMO6P
      eBioscience FlowRNA Probe Sets
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
      Search antibodies-online for antibodies for FMO6P
      Search antibodies-online for kits for FMO6P
      Search antibodies-online for peptides for FMO6P
      Search antibodies-online for proteins for FMO6P
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      FMO6P gene at Home site.
    Version: 3.12.234 23 Oct 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4