FMNL1 Gene
protein-coding GIFtS : 53
GCID: GC17 P043299
formin-like 1 (Previous name: formin-like ) (Previous symbols: C17orf1B, FMNL )
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Aliasesfor FMNL1 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Formin-Like 1 1 2 CLL-Associated Antigen KW-132 3 C17orf1B1 2 3 5 Formin-Like1 FMNL1 2 3 5 FHOD42 C17orf11 2 3 KW-132 Leukocyte Formin2 3 Formin-Like Protein 12
Export aliases for FMNL1 gene to outside databases Previous GC identifers: GC17P043774 GC17P040656 GC17P039060
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Summariesfor FMNL1 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for FMNL1 : This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. An alternative splice variant has been described but its full length sequence has not been determined. (provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: FMNL_HUMAN, O95466 Function : May play a role in the control of cell motility and survival of macrophages (By similarity). Plays a role inthe regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape Gene Wiki entry for FMNL1
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Genomic Viewsfor FMNL1 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000017.10 NC_018928.1 NT_010783.15 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the FMNL1 gene promoter: c-Fos ISGF-3 AP-1 MAZR JunB Fra-1 FosB JunD HSF2 c-Jun Other transcription factors Search SABiosciences Chromatin IP Primers for FMNL1 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat FMNL1
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 17q21 Ensembl cytogenetic band: 17q21.31 HGNC cytogenetic band: 17q21.31 FMNL1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 17 GeneLoc Exon Structure
GeneLoc location for GC17P043299: view genomic region
(about GC identifiers )
Start:
43,298,811 bp from pter
End:
43,324,687 bp from pter
Size:
25,877 bases
Orientation:
plus strand
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Proteinsfor FMNL1 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: FMNL_HUMAN, O95466 (See
protein sequence )Recommended Name: Formin-like protein 1 Size : 1100 amino acids; 121854 Da
Subunit : Interacts with RAC1, PFN1 and PFN2 (By similarity). Interacts (activated by RAC1) with SRGAP2 (via SH3domain); regulates the actin filament severing activity of FMNL1
Subcellular location : Cytoplasm (By similarity). Cell membrane; Lipid-anchor. Cytoplasmic vesicle, phagosome (Bysimilarity). Note=Recruited to actin-rich phagosomes during phagocytosis. Translocates to the plasma membrane upon activation by RAC1 (By similarity)
Subcellular location : Isoform 3: Cytoplasm, cell cortex. Cell projection, bleb. Note=Colocalized with F-actin in blebprotrusions
Sequence caution : Sequence=AAH21906.1; Type=Erroneous initiation; Sequence=CAA07870.1; Type=Erroneous initiation;
Secondary accessions : D2DGW2 Q6DKG5 Q6IBP3 Q86UH1 Q8N671 Q8TDH1 Q96H10Alternative splicing : 3 isoforms : O95466-1 O95466-2 O95466-3 (Due to intron retention. Constitutively activated form, probably due to alterations in the DAD domain)Explore the universe of human proteins at neXtProt for FMNL1: NX_O95466 Post-translational modifications:
Myristoylation mediates membrane localization and blebbing1
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_O95466 FMNL1 Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins: NP_005883.2 ENSEMBL proteins: ENSP00000329219 ENSP00000465474 ENSP00000465137 ENSP00000466711 ENSP00000468301 ENSP00000327442 Human Recombinant Protein Products: Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view) : About this table
FMNL1 for ontologies About GeneDecksing FMNL1 Antibody Products: Assay Products for FMNL1:
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Protein
Domains / Familiesfor FMNL1 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
FMNL1 for domains About GeneDecksing 5/7 InterPro domains/families (see all 7 ):
Graphical View of Domain Structure for InterPro Entry O95466 ProtoNet protein and cluster: O95466
2 Blocks protein families : IPB003104 Actin-binding FH2 IPB010472 Diaphanous FH3 UniProtKB/Swiss-Prot: FMNL_HUMAN, O95466 Domain : The DAD domain regulates activation via by an autoinhibitory interaction with the N-terminus. Thisautoinhibition is released upon competitive binding of an activated GTPase. The release of DAD allows the FH2 domain to then nucleate and elongate nonbranched actin filaments (By similarity) Similarity : Belongs to the formin homology familySimilarity : Contains 1 DAD (diaphanous autoregulatory) domainSimilarity : Contains 1 FH2 (formin homology 2) domainSimilarity : Contains 1 GBD/FH3 (Rho GTPase-binding/formin homology 3) domain
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Functionfor FMNL1 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Function Summary: UniProtKB/Swiss-Prot: FMNL_HUMAN, O95466 Function : May play a role in the control of cell motility and survival of macrophages (By similarity). Plays a role inthe regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape
Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for FMNL1 (see all 4 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for FMNL1OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: FMNL1 (NM_005892 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FMNL1 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat FMNL1
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FMNL1
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6 ): About this table
FMNL1 for ontologies About GeneDecksing
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Pathways & Interactionsfor FMNL1 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FMNL1 STRING Interaction
Network Preview (showing 5 interactants - click image to see 9)5/11 Interacting proteins for FMNL1 (O95466 1 , 2 , 3 ENSP00000329219 4 ) via UniProtKB, MINT, STRING , and/or I2D (see all 11 )About this table Gene Ontology (GO): 5 biological process terms (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0006929 substrate-dependent cell migration
IEA -- GO:0008360 regulation of cell shape
IMP -- GO:0009987 cellular process
-- -- GO:0030866 cortical actin cytoskeleton organization
IMP -- GO:0051014 actin filament severing
ISS --
FMNL1 for ontologies About GeneDecksing
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Drugs & Compoundsfor FMNL1 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for FMNL1 Search CenterWatch for drugs/clinical trials and news about FMNL1 / FMNL
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Transcriptsfor FMNL1 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for FMNL1 gene: NM_005892.3 Unigene Cluster for FMNL1:
Formin-like 1 Hs.100217 [show with all ESTs ] Unigene Representative Sequence: AK131091 12 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000592415 ENST00000331495 (uc002iin.3 uc021tyj.1 ) ENST00000585852 ENST00000592006 ENST00000592527 ENST00000587856 ENST00000591434 ENST00000587489 ENST00000586643 ENST00000589911 ENST00000586092 ENST00000328118 (uc002iio.3 uc002iip.1 uc002iiq.3 uc010dag.3 )Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for FMNL1 (see all 4 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for FMNL1OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: FMNL1 (NM_005892 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FMNL1 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat FMNL1
Additional cDNA sequence: AF432213.1 AJ008112.1 AJ008113.1 AJ008114.1 AJ008115.1 AJ008116.1 AJ008117.1 AJ008118.1 AJ008119.1 AJ008120.1 AJ008121.1 AJ008122.1 AJ008123.1 AJ008124.1 AJ008126.1 AJ008127.1 AJ008128.1 AJ008129.1 AJ008130.1 AJ008131.1 AJ008132.1 AJ008133.1 AK131091.1 AY278319.1 BC001710.1 BC009000.2 BC021906.1 BC042925.1 BC064572.1 BC073988.1 CR456759.1 FJ534522.1
23 DOTS entries : DT.305475 DT.95294122
DT.97844663 DT.96086455 DT.99951976 DT.100718200 DT.100839865 DT.120945533 DT.75139817 DT.120945560 DT.99953217 DT.75188035 DT.95294135 DT.120945631 DT.91749549 DT.97815418 DT.100820826 DT.97801671 DT.91785298 DT.95070943 DT.99965614 DT.120945688 DT.97813760 24/213 AceView cDNA sequences (see all 213 ):
AJ008129 BQ878623 BU616265 BQ109528 AJ008120 CA308198 BI028593 BU195430 AJ008115 AJ008118 BM049444 AF432213 CD369618 BM917028 AA381887 BE241986 BU543403 BG235961 CR616114 BC001710 NM_005892 CA419185 AI470260 BI909099 GeneLoc Exon Structure 5/12 Alternative Splicing Database (ASD) splice patterns (SP) for FMNL1 (see all 12 ) About this scheme ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b · 13c ^ 14a · 14b ^ 15 ^ 16 ^ 17 ^ SP1 :                                                     SP2 :                   -     -               -                 SP3 :                                                     SP4 :                                                     SP5 :                                     -                
ExUns: 18 ^ 19 ^ 20 ^ 21a · 21b ^ 22a · 22b ^ 23a · 23b · 23c ^ 24 ^ 25 ^ 26a · 26b ^ 27 SP1 :                           -     SP2 :                               SP3 :                               SP4 :                               SP5 :                              
ECgene alternative splicing isoforms for FMNL1
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Expression for FMNL1 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section FMNL1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: GACCTTATTT
About this image See FMNL1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for FMNL1 SOURCE GeneReport for Unigene cluster: Hs.100217 UniProtKB/Swiss-Prot: FMNL_HUMAN, O95466 Tissue specificity : Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas SABiosciences Custom PCR Arrays for FMNL1 Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for FMNL1Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat FMNL1 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat FMNL1 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat FMNL1 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FMNL1
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Orthologsfor FMNL1 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of eukaryotes.
Orthologs for FMNL1 gene from 7/24 species (see all 24 ) About this table
ENSEMBL Gene Tree for FMNL1 (if available)TreeFam Gene Tree for FMNL1 (if available)
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Paralogsfor FMNL1 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for FMNL1 gene DIAPH1 2 DAAM1 2 FMNL3 2 FHDC1 2 DAAM2 2 FMNL2 2 INF2 2 GRID2IP 2 FMN1 2 DIAPH2 2 DIAPH3 2 FMN2 2 4 SIMAP similar genes for FMNL1 using alignment to 6 protein entries: FMNL_HUMAN (see all proteins ):FLJ00304 DKFZp762B245 FMNL2 FMNL3
FMNL1 for paralogs About GeneDecksing
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Genomic Variantsfor FMNL1 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 17 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for FMNL1 (43298811 - 43324687 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for FMNL1 1 CNV : 34646
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing FMNL1
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Disorders
/ Diseasesfor FMNL1 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Novoseek ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
FMNL1 for disorders About GeneDecksing
OMIM gene information: 604656
OMIM disorders : --4 diseases for FMNL1 : About MalaCards non-hodgkin lymphoma frontotemporal dementia hodgkin's lymphoma dementia 1 disease from the University of Copenhagen DISEASES database for FMNL1 :Chondrosarcoma 3 Novoseek disease relationships for FMNL1 gene About this table
Disease
-log (P-Val)
Hits
PubMed IDs for Articles with Shared Sentences (# sentences)
chondrosarcoma
61.2
1
12684686 (1)
glioblastoma
49.4
1
12684686 (1)
melanoma
26.5
1
12684686 (1)
Export disorders for FMNL1 gene to outside databases
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Publicationsfor FMNL1 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for FMNL1 gene, integrated from 9 sources (see all 31 ): (articles sorted by number of sources associating them with FMNL1) Utopia : connect your pdf to the dynamic world of online information
The NIK protein kinase and C17orf1 genes: chromosomal mapping, gene structures and mutational screening in frontotemporal dementia and parkinsonism linked to chromosome 17. (PubMed id 9799091) 1 , 2 , 3 Aronsson F.C.... Brookes A.J. (1998) Formin-like 1 (FMNL1) is regulated by N-terminal myristoylation and induces polarized membrane blebbing. (PubMed id 19815554) 1 , 2 , 9 Han Y.... Krackhardt A.M. (2009) Bi-modal regulation of a formin by srGAP2. (PubMed id 21148482) 1 , 2 Mason F.M....Soderling S.H. (2011) Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983) 1 , 2 Olsen J.V....Mann M. (2006) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 Gerhard D.S....Malek J. (2004) Identification and characterization of human FMNL1, FMNL2 and FMNL3 genes in silico. (PubMed id 12684686) 1 , 9 Katoh M. and Katoh M. (2003) Human leukocyte formin: a novel protein expressed in lymphoid malignancies and associated with Akt. (PubMed id 14592423) 1 , 9 Favaro P.M....Saad S.T. (2003) Identification and characterization of human DAAM2 gene in silico. (PubMed id 12632087) 1 , 9 Katoh M. and Katoh M. (2003) Initial characterization of the human central proteome. (PubMed id 21269460) 2 Burkard T.R.... Colinge J. (2011) A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473) 1 Wagner S.A....Choudhary C. (2011)
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External Searches for FMNL1 gene
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Genome Databases showing FMNL1 gene
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miRBase ,
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and/or
H-InvDB )
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Other Databases showing FMNL1 gene
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Specialized Databases showing FMNL1 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for FMNL1 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for FMNL1 gene: Search GeneIP for patents involving FMNL1 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor FMNL1 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
OriGene Antibodies for FMNL1 OriGene shRNA RFP for FMNL1 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for FMNL1 OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for FMNL1 OriGene Protein Over-expression Lysate for FMNL1 Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for FMNL1 OriGene 3'-UTR Clone for FMNL1 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for FMNL1 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for FMNL1 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for FMNL1 OriGene Custom Protein Services for FMNL1 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FMNL1 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing FMNL1 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat FMNL1 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat FMNL1 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat FMNL1 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat FMNL1
Search Tocris compounds for FMNL1
FMNL1 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FMNL1
ThermoFisher Antibodies for FMNL1
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat FMNL1
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