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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

FMN2 Gene

protein-coding GIFtS: 52
GCID: GC01P240177

formin 2

Explore 7 diseases affiliated with
FMN2 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Formin 2¹ ²
Formin-2¹

External Ids:	HGNC: 14074¹	Entrez Gene: 56776²	Ensembl: ENSG00000155816⁷	OMIM: 606373⁵	UniProtKB: Q9NZ56³

Export aliases for FMN2 gene to outside databases

Previous GC identifers: GC01P238337 GC01P235709 GC01P236553 GC01P237296 GC01P236502 GC01P210713

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FMN2:

Formin homology (FH) domain proteins (see FMN1; MIM 136535) play a role in cytoskeletal organization and/or

establishment of cell polarity.(supplied by OMIM, Apr 2010)

UniProtKB/Swiss-Prot: FMN2_HUMAN, Q9NZ56

Function: Required for asymmetric spindle positioning, asymmetric oocyte division and polar body extrusion during

female germ cell meiosis (By similarity). Actin-binding protein that is involved in actin cytoskeleton assembly and

reorganization. Acts as an actin nucleation factor and promotes assembly of actin filaments together with SPIRE1 and

SPIRE2. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin

cytoskeleton dynamics and intracellular transport. Plays a role in responses to DNA damage, cellular stress and

hypoxia by protecting CDKN1A against degradation, and thereby plays a role in stress-induced cell cycle arrest.

Protects cells against apoptosis by protecting CDKN1A against degradation

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_167186.1

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the FMN2 gene promoter:
TBP AhR GCNF HTF AP-2gamma Gfi-1 GATA-1 Arnt GCNF-1 GCNF-2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: FMN2 promoter sequence

Search SABiosciences Chromatin IP Primers for FMN2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FMN2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q43 Ensembl cytogenetic band: 1q43 HGNC cytogenetic band: 1q43

FMN2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FMN2 gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P240177: view genomic region (about GC identifiers)

Start:	240,177,648 bp from pter	End:	240,638,489 bp from pter
Size:	460,842 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: FMN2_HUMAN, Q9NZ56 (See protein sequence)

Recommended Name: Formin-2

Size: 1722 amino acids; 180106 Da

Subunit: Interacts with SPIRE1. Binds actin. Interacts with CDKN1A

Subcellular location: Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Cytoplasm, cytosol. Cell membrane;

Peripheral membrane protein; Cytoplasmic side (By similarity). Cytoplasmic vesicle membrane; Peripheral membrane

protein; Cytoplasmic side (By similarity). Cytoplasm, cell cortex (By similarity). Nucleus, nucleolus. Note=Recruited

to the membranes via its interaction with SPIRE1. Colocalizes with the actin cytoskeleton. Detected at the cleavage

furrow during asymmetric oocyte division and polar body extrusion (By similarity)

Sequence caution: Sequence=AAF72884.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of unknown

origin in the C-terminal part;

2 PDB 3D structures from and Proteopedia for FMN2:

2YLE (3D)

3R7G (3D)

Secondary accessions: B0QZA7 Q59GF6 Q5VU37 Q9NZ55

Explore the universe of human proteins at neXtProt for FMN2: NX_Q9NZ56

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9NZ56

FMN2 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_064450.3

ENSEMBL proteins:

ENSP00000409308 ENSP00000318884 ENSP00000388922 ENSP00000437918 ENSP00000439136

Human Recombinant Protein Products:

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	Novus Biologicals FMN2 Protein
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	Browse ProSpec Recombinant Proteins
	Uscn Proteins for FMN2

Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005575	cellular_component	ND	--
GO:0005622	intracellular	--	--
GO:0005730	nucleolus	IDA	--
GO:0005829	cytosol	IDA	--
GO:0005938	cell cortex	ISS	--

FMN2 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for FMN2

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

FMN2 for domains About GeneDecksing

4 InterPro domains/families:

IPR015425 FH2_actin-bd

IPR003104 Actin-bd_FH2/DRF_autoreg

IPR000591 DEP_dom

IPR009408 Formin_homology_1

Graphical View of Domain Structure for InterPro Entry Q9NZ56

ProtoNet protein and cluster: Q9NZ56

2 Blocks protein families:

IPB003104 Actin-binding FH2

IPB009408 Formin Homology 1

UniProtKB/Swiss-Prot: FMN2_HUMAN, Q9NZ56

Similarity: Belongs to the formin homology family. Cappuccino subfamily

Similarity: Contains 1 FH1 (formin homology 1) domain

Similarity: Contains 1 FH2 (formin homology 2) domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: FMN2_HUMAN, Q9NZ56

Function: Required for asymmetric spindle positioning, asymmetric oocyte division and polar body extrusion during

female germ cell meiosis (By similarity). Actin-binding protein that is involved in actin cytoskeleton assembly and

reorganization. Acts as an actin nucleation factor and promotes assembly of actin filaments together with SPIRE1 and

SPIRE2. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin

cytoskeleton dynamics and intracellular transport. Plays a role in responses to DNA damage, cellular stress and

hypoxia by protecting CDKN1A against degradation, and thereby plays a role in stress-induced cell cycle arrest.

Protects cells against apoptosis by protecting CDKN1A against degradation

Induction: Up-regulated in response to cellular stress, hypoxia and DNA damage via NF-kappa-B

miRNA Products:		OriGene 3'-UTR Clone: FMN2 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FMN2
		8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate FMN2 (see all 10):
		hsa-miR-92a hsa-miR-25 hsa-miR-367 hsa-miR-32 hsa-miR-587 hsa-miR-144 hsa-miR-4325 hsa-miR-363

		SwitchGear 3'UTR luciferase reporter plasmid: FMN2 3' UTR sequence

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Gene Editing
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In Situ Assay
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Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003674	molecular_function	ND	--
GO:0003779	actin binding	IDA	--

FMN2 for ontologies           About GeneDecksing

Animal Models:
     Mouse knock-out Fmn2^tm1Led for FMN2
     2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Fmn2):

behavior/neurological

reproductive system

FMN2 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Dorso-ventral axis formation

Dorso-ventral axis formation

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

1 Kegg Pathway (Kegg details for FMN2):

Dorso-ventral axis formation

FMN2 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for FMN2

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for FMN2 (ENSP00000318884⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SPIRE1	ENSP00000387266⁴	STRING: ENSP00000387266

About this table

Gene Ontology (GO): 5/15 biological process terms (GO ID links to tree view) (see all 15): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006915	apoptotic process	IMP	--
GO:0006974	response to DNA damage stimulus	IMP	--
GO:0007132	meiotic metaphase I	ISS	--
GO:0007275	multicellular organismal development	IEA	--
GO:0016192	vesicle-mediated transport	ISS	--

FMN2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for FMN2
Search CenterWatch for drugs/clinical trials and news about FMN2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for FMN2 gene:

NM_020066.4

Unigene Cluster for FMN2:

Formin 2

Hs.24889 [show with all ESTs]

Unigene Representative Sequence: NM_020066

7 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000447095 ENST00000319653(uc010pyd.2 uc010pye.2 uc010pyg.2)

ENST00000463398 ENST00000441342 ENST00000496950 ENST00000545751(uc010pyf.1)

ENST00000543681(uc001hyr.3)

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FMN2
		8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate FMN2 (see all 10):
		hsa-miR-92a hsa-miR-25 hsa-miR-367 hsa-miR-32 hsa-miR-587 hsa-miR-144 hsa-miR-4325 hsa-miR-363

		SwitchGear 3'UTR luciferase reporter plasmid: FMN2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FMN2

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FMN2 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FMN2 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FMN2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FMN2

Additional cDNA sequence:

AB209153.1 AF218941.1 AF218942.1 AF225426.1 AK297716.1 AK297755.1 AK298141.1 BC112335.1

BC112361.1

3 DOTS entries:

DT.454703 DT.121414266 DT.92417146

24/41 AceView cDNA sequences (see all 41):

BG222948 BC014364 BU172928 BG059879 AI168018 AV726586 BQ285980 BX508513

BX106210 AI342859 BQ014865 AV725246 CA942375 CA867078 AF225426 BQ269338

AI419119 AW022668 AF218942 AI140954 AI167177 AI027439 BE788369 AI034147

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

FMN2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCTAAGTATA

About this image

FMN2 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Ovary

Primary Follicle

Primary Oocyte

Female Gametocytes, Germ Cells

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

PureStem™ progenitor EN27 (Embryonic Progenitor Cell)

Definitive endoderm-like cells (A scalable, suspensi...)

See FMN2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FMN2

SOURCE GeneReport for Unigene cluster: Hs.24889

UniProtKB/Swiss-Prot: FMN2_HUMAN, Q9NZ56

Tissue specificity: Expressed almost exclusively in the developing and mature central nervous system

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FMN2

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FMN2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for FMN2 gene from 5/16 species (see all 16) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	FMN2¹	formin 2	66.75(n) 68.39(a)		775973 XM_001235547.2 XP_001235548.2
lizard (Anolis carolinensis)	Reptilia	FMN2⁶	--	58(a)	1 ↔ 1	1(216961336-217140654)
African clawed frog (Xenopus laevis)	Amphibia	CA788981.1²	--	75.86(n)		CA788981.1
zebrafish (Danio rerio)	Actinopterygii	CT027692.1⁶ fmn2b⁶ (see all 3)	formin 2b (see all 3)	74(a) 48(a) (see all 3)	1 ↔ many 1 ↔ many (see all 3)	17(19603302-19631169) 12(48614757-48706677)
fruit fly (Drosophila melanogaster)	Insecta	capu³	eggshell formation actin binding	38(a)		--

ENSEMBL Gene Tree for FMN2 (if available)
TreeFam Gene Tree for FMN2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for FMN2 gene

DIAPH1² DAAM1² FMNL3² FHDC1² FMNL1² DAAM2² FMNL2² INF2²

GRID2IP² FMN1² DIAPH2² DIAPH3²

1 SIMAP similar gene for FMN2 using alignment to 6 protein entries: FMN2_HUMAN (see all proteins):

FMN1

FMN2 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for FMN2
PGOHUM00000241677

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs191157997^1,2	C,	--	240253228(+)	`AAAAAC/TTGTGG`	1	--	us2k¹		0	--	--	--	--
rs78976984^1,2	C,	--	240253276(+)	`TGTGAT/CCTTGG`	1	--	us2k¹		2		CSA WA	120
rs1418049^1,2	C,F,A,H,	--	240253320(-)	`TAATTA/GAAGCA`	1	--	us2k¹ tfbs³		104		NS EA PA EU CA WA NA CSA	6294
rs180806443^1,2		--	240253433(+)	`AACTGC/TCACTG`	1	--	us2k¹		0	--	--	--	--
rs149401503^1,2		--	240253556(+)	`AAAGAC/TGTTCT`	1	--	us2k¹		0	--	--	--	--
rs186442674^1,2		--	240253591(+)	`ATTCAA/GAGTAC`	1	--	us2k¹		0	--	--	--	--
rs144811131^1,2		--	240253596(+)	`AAGTAC/TCTCAG`	1	--	us2k¹		0	--	--	--	--
rs77597751^1,2	C,	--	240253626(+)	`TTCTAA/GTAGCT`	1	--	us2k¹		3		CSA WA EA	240
rs148154725^1,2		--	240253661(+)	`AGCCTA/GGATTC`	1	--	us2k¹		0	--	--	--	--
rs142016408^1,2		--	240253789(+)	`AAAGCA/GTTTAC`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for FMN2 (240177648 - 240427648 bp, first 250kb of FMN2)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 32 variations for FMN2
15/27 CNVs (see all 27): 74954 74950 74955 74953 97689 74956 3337 0262 31696 84927 84930 48287 66286 43766 74958
5 Indels: 39702 60962 39701 44536 44535
Human Gene Mutation Database (HGMD): FMN2

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FMN2

DNA2.0 Custom Variant and Variant Library Synthesis for FMN2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

FMN2 for disorders           About GeneDecksing

OMIM gene information: 606373    OMIM disorders: --

7 diseases for FMN2:    About MalaCards

dissecting aortic aneurysm aortic aneurysm coronary heart disease multiple sclerosis

nephropathy infertility atherosclerosis

Human Genome Epidemiology (HuGE) Navigator: FMN2 (8 documents)

Export disorders for FMN2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for FMN2 gene, integrated from 9 sources (see all 26):
(articles sorted by number of sources associating them with FMN2)

Utopia: connect your pdf to the dynamic
world of online information

Formin-2, a novel formin homology protein of the cappuccino subfamily, is highly expressed in the developing and adult central nervous system. (PubMed id 10781961)^{1, 2, 3, 9} Leader B. and Leder P. (2000)
Molecular basis of actin nucleation factor cooperativ ity: crystal structure of the Spir-1 kinase non-catalytic C-lobe domain (KIND) a8cformin-2 formin SPIR interaction motif (FSI) complex. (PubMed id 21705804)^{1, 2} Zeth K....Kerkhoff E. (2011)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{1, 2} Gregory S.G.... Bentley D.R. (2006)
Characterization and mutation analysis of the human formin-2 (FMN2) gene in women with unexplained infertility. (PubMed id 15866570)^{1, 9} Ryley D.A....Gray M.R. (2005)
Characterization of FMN2 gene at human chromosome 1q43. (PubMed id 15289902)^{1, 9} Katoh M. and Katoh M. (2004)
Effects of genistein on beta-catenin signaling and su bcellular distribution of actin-binding proteins in human umbilical CD105-posit ive stromal cells. (PubMed id 20082305)^{2, 9} Shieh D.B....Liou Y.M. (2010)
Identification of a short Spir interaction sequence a t the C-terminal end of formin subgroup proteins. (PubMed id 19605360)^{1, 9} Pechlivanis M....Kerkhoff E. (2009)
Identification and functional characterization of FMN2, a regulator of the cyclin-dependent kinase inhibitor p21. (PubMed id 23375502)² Yamada K.... Lamond A.I. (2013)
Differential role of actin-binding proteins in controlling the adipogenic differentiation of human CD105-positive Wharton's Jelly cells. (PubMed id 22330775)² Peng K.W. and Liou Y.M. (2012)
Structure and function of the interacting domains of Spire and Fmn- family formins. (PubMed id 21730168)² Vizcarra C.L.... Eck M.J. (2011)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 56776	HGNC: 14074	AceView: FMN2.3	Ensembl:ENSG00000155816	euGenes: HUgn56776
ECgene: FMN2	Kegg: 56776	H-InvDB: FMN2

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for FMN2	Pharmacogenomics, SNPs, Pathways

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