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FLVCR1-AS1 Gene

RNA gene   GIFtS: 26
GCID: GC01M213030

FLVCR1 Antisense RNA 1 (Head To Head)

(Previous names: non-protein coding RNA 292, FLVCR1 antisense RNA 1 (non-protein...)
(Previous symbol: NCRNA00292)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Subcategory (RNA class): lncRNA

Quality score for this RNA gene is 3

Aliases
FLVCR1 Antisense RNA 1 (Head To Head)1 2
LQK12 3 5
NCRNA002921 2
FLVCR1 Antisense RNA 11 3
FLVCR1 Antisense RNA 1 (Non-Protein Coding)1
Non-Protein Coding RNA 2921

External Ids:    HGNC: 390771   Entrez Gene: 6429462   Ensembl: ENSG000001984687   OMIM: 6108645   UniProtKB: Q8TAF53   
ORGUL members:         

Export aliases for FLVCR1-AS1 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for FLVCR1-AS1 Gene:
FLVCR1-AS1 (FLVCR1 antisense RNA 1 (head to head)) is an RNA gene, and is affiliated with the lncRNA class. Diseases associated with FLVCR1-AS1 include leukemia.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NC_018912.2  NT_004487.20  
Regulatory elements:
   Search for regulatory transcription factor binding sites for FLVCR1-AS1
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
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Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FLVCR1-AS1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q32.3   Ensembl cytogenetic band:  1q32.3   HGNC cytogenetic band: 1q32.3

FLVCR1-AS1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FLVCR1-AS1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M213030:  view genomic region     (about GC identifiers)

Start:
213,025,450 bp from pter      End:
213,031,480 bp from pter
Size:
6,031 bases      Orientation:
minus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for FLVCR1-AS1

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: LQK1_HUMAN, Q8TAF5 (See protein sequence)
Recommended Name: Putative uncharacterized protein LQK1  
Size: 88 amino acids; 10021 Da
Caution: Product of a dubious gene prediction

Explore the universe of human proteins at neXtProt for FLVCR1-AS1: NX_Q8TAF5

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    LNCRNA: Long non-coding RNAs

    ProtoNet protein and cluster: Q8TAF5


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Animal Models:
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FLVCR1-AS1
    Interactions:

        Search GeneGlobe Interaction Network for FLVCR1-AS1

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FLVCR1-AS1 (LQK1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    Unigene Cluster for FLVCR1-AS1:

    FLVCR1 antisense RNA 1 (head to head)
    Hs.552649  [show with all ESTs]
    Unigene Representative Sequence: AK092887
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000356684(lincRNA) ENST00000426161(lincRNA)(uc001hjr.4) ENST00000424044(lincRNA)(uc001hjs.4)

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    Additional mRNA sequence: 

    AK092887.1 AY030238.1 AY030239.1 NR_027285.1 NR_027286.1 

    4 DOTS entries:

    DT.211556  DT.121450121  DT.87046397  DT.99936608 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for FLVCR1-AS1    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3
    SP1:                                    
    SP2:                    -     -         
    SP3:                    -               


    ECgene alternative splicing isoforms for FLVCR1-AS1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    Expression evidence for FLVCR1-AS1:none

    FLVCR1-AS1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CATATTCAGT
    FLVCR1-AS1 Expression
    About this image

    FLVCR1-AS1 Protein expression data from MOPED1, PaxDb2 and MaxQB3 --

    SOURCE GeneReport for Unigene cluster: Hs.552649

    UniProtKB/Swiss-Prot: LQK1_HUMAN, Q8TAF5
    Tissue specificity: Expressed in a wide variety of tissues

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    ENSEMBL Gene Tree for FLVCR1-AS1 (if available)
    TreeFam Gene Tree for FLVCR1-AS1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    7 SNPs for FLVCR1-AS1    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs120225401,2
    C--213029583(+) GGGGCG/AGGCGG 2 -- ds50014Minor allele frequency- A:0.19NA WA EA 360
    rs774272031,2
    C,F--213029591(+) CGGAGG/CGGGGG 2 -- ds50012Minor allele frequency- C:0.08NA 122
    rs765424791,2
    ----213029557(+) AAAAAG/AGCAGG 2 -- ds50011Minor allele frequency- A:0.00NA 2
    rs2011467211,2
    ----213029459(+) AAAAA-/AGAAAG 2 -- ds50010--------
    rs722709341,2
    ----213029471(+) AAAAG-/AAAAGA 2 -- ds50010--------
    rs717820641,2
    ----213029460(+) CTGTC-/AAAAAA 2 -- ds50010--------
    rs803367851,2
    ----213029558(+) AAAAAG/ACAGGG 2 -- ds50011Minor allele frequency- A:0.50NA 2

    HapMap Linkage Disequilibrium report for FLVCR1-AS1 (213025450 - 213031480 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for FLVCR1-AS1: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FLVCR1-AS1
    DNA2.0 Custom Variant and Variant Library Synthesis for FLVCR1-AS1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610864    OMIM disorders: --

    1 disease for FLVCR1-AS1:    
    About MalaCards
    leukemia


    FLVCR1-AS1 for disorders           About GeneDecksing


    Export disorders for FLVCR1-AS1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FLVCR1-AS1 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with FLVCR1-AS1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genomic structure and evolutionary context of the human feline leukemia virus subgroup C receptor (hFLVCR) gene: evidence for block duplications and de novo gene formation within duplicons of the hFLVCR locus. (PubMed id 11943475)1, 2, 3 Lipovich L.... Quigley J.G. (Gene 2002)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (Nature 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 642946 HGNC: 39077 Ensembl:ENSG00000198468 euGenes: HUgn642946 ECgene: FLVCR1-AS1
    H-InvDB: FLVCR1-AS1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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      --

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FLVCR1-AS1 gene:
    Search GeneIP for patents involving FLVCR1-AS1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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