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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FLRT1 Gene

protein-coding   GIFtS: 51
GCID: GC11P063871

Fibronectin Leucine Rich Transmembrane Protein 1
  Search for FLRT1
at
MalaCards
 

Aliases
for FLRT1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section
Aliases
Fibronectin Leucine Rich Transmembrane Protein 11 2
Fibronectin-Like Domain-Containing Leucine-Rich Transmembrane Protein 12 3
Leucine-Rich Repeat Transmembrane Protein FLRT12

External Ids:    HGNC: 37601   Entrez Gene: 237692   Ensembl: ENSG000001265007   OMIM: 6048065   UniProtKB: Q9NZU13   

Export aliases for FLRT1 gene to outside databases

Previous GC identifers: GC11M066466 GC11M065550 GC11P064122 GC11P063646 GC11P063627 GC11P060200


Summaries
for FLRT1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for FLRT1 Gene:
This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. The family members
may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich
proteoglycans found in the extracellular matrix. The encoded protein shares sequence similarity with two other
family members, FLRT2 and FLRT3. This gene is expressed in kidney and brain. (provided by RefSeq, Jul 2008)

GeneCards Summary for FLRT1 Gene: 
FLRT1 (fibronectin leucine rich transmembrane protein 1) is a protein-coding gene. GO annotations related to this gene include receptor signaling protein activity and protein binding, bridging. An important paralog of this gene is PODN.

UniProtKB/Swiss-Prot: FLRT1_HUMAN, Q9NZU1
Function: May have a function in cell adhesion and/or receptor signaling




Genomic Views
for FLRT1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NT_167190.1  NC_018922.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FLRT1 gene promoter:
         COUP-TF1   Bach1   Egr-1   COUP   HNF-4alpha2   HNF-4alpha1   FOXL1   S8   COUP-TF   FOXO4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: FLRT1 promoter sequence
   Search SABiosciences Chromatin IP Primers for FLRT1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FLRT1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13.1   Ensembl cytogenetic band:  11q13.1   HGNC cytogenetic band: 11q13.1

FLRT1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FLRT1 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P063871:  view genomic region     (about GC identifiers)

Start:
 63,870,660 bp from pter      End:
 63,886,645 bp from pter
Size:
 15,986 bases      Orientation:
 plus strand

Proteins
for FLRT1 gene

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section
UniProtKB/Swiss-Prot: FLRT1_HUMAN, Q9NZU1 (See protein sequence)
Recommended Name: Leucine-rich repeat transmembrane protein FLRT1 precursor  
Size: 646 amino acids; 71358 Da
Subcellular location: Membrane; Single-pass type I membrane protein (Probable)
Sequence caution: Sequence=AAF28459.1; Type=Erroneous initiation; Sequence=AAH18370.1; Type=Erroneous initiation;
Sequence=AAQ88675.1; Type=Erroneous initiation; Sequence=BAF82620.1; Type=Erroneous initiation;
Sequence=EAW74194.1; Type=Erroneous initiation;
Secondary accessions: Q8WVA2

Explore the universe of human proteins at neXtProt for FLRT1: NX_Q9NZU1

Explore proteomics data for FLRT1 at MOPED 

Post-translational modifications:

  • UniProtKB: N-glycosylated
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NZU1

    • FLRT1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    FLRT1 Protein Expression
    REFSEQ proteins: NP_037412.2  
    ENSEMBL proteins: 
     ENSP00000246841  

    Human Recombinant Protein Products for FLRT1: 
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    R&D Systems Recombinant & Natural Proteins for FLRT1
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for FLRT1
    OriGene Protein Over-expression Lysate for FLRT1
    OriGene MassSpec for FLRT1 
    OriGene Custom Protein Services for FLRT1
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    Novus Biologicals FLRT1 Protein
    Novus Biologicals FLRT1 Lysate
    Sino Biological Recombinant Protein for FLRT1
    Sino Biological Cell Lysate for FLRT1 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for FLRT1 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005578proteinaceous extracellular matrix NAS10644439
    GO:0005887integral to plasma membrane NAS10644439

    FLRT1 for ontologies           About GeneDecksing



    FLRT1 Antibody Products: 
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    ThermoFisher Antibody for FLRT1
    LSBio Antibodies in human, mouse, rat for FLRT1 

    Assay Products for FLRT1: 
    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for FLRT1 
    Cloud-Clone Corp. CLIAs for FLRT1

    Protein Domains /
    Families
    for FLRT1 gene

    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    		 HGNC Gene Families: 
    FN3: Fibronectin type III domain containing

    5/6 InterPro protein domains (see all 6):
     IPR000483 Cys-rich_flank_reg_C
     IPR001611 Leu-rich_rpt
     IPR003961 Fibronectin_type3
     IPR013783 Ig-like_fold
     IPR003591 Leu-rich_rpt_typical-subtyp

    Graphical View of Domain Structure for InterPro Entry Q9NZU1

    ProtoNet protein and cluster: Q9NZU1

    2 Blocks protein domains:
    IPB000372 Cysteine-rich flanking region
    IPB000483 Cysteine-rich flanking region


    UniProtKB/Swiss-Prot: FLRT1_HUMAN, Q9NZU1
    Similarity: Contains 1 fibronectin type-III domain
    Similarity: Contains 10 LRR (leucine-rich) repeats
    Similarity: Contains 1 LRRCT domain
    Similarity: Contains 1 LRRNT domain


    FLRT1 for domains           About GeneDecksing


    Function
    for FLRT1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section
    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FLRT1_HUMAN, Q9NZU1
    Function: May have a function in cell adhesion and/or receptor signaling

         Genatlas biochemistry entry for FLRT1:
    fibronectin,leucine rich transmembrane protein1,extracellular matrix protein,expressed in kidney and brain

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005057receptor signaling protein activity NAS10644439
    GO:0005515protein binding ----
    GO:0030674protein binding, bridging NAS10644439
         
    FLRT1 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Flrt1):
     no phenotypic analysis 

    FLRT1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Flrt1tm1.1Kln for FLRT1

       inGenious Targeting Laboratory - Custom generated mouse model solutions for FLRT1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for FLRT1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FLRT1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FLRT1 

    miRNA
    Products:            		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FLRT1
    8 QIAGEN miScript miRNA Assays for microRNAs that regulate FLRT1:
    hsa-miR-502-5p hsa-miR-196a hsa-miR-544 hsa-miR-196b hsa-miR-654-3p hsa-miR-145 hsa-miR-205* hsa-miR-552
    SwitchGear 3'UTR luciferase reporter plasmid: FLRT1 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for FLRT1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FLRT1

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for FLRT1
    Sirion Biotech Customized adenovirus for overexpression of FLRT1

    Clone
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    OriGene clones in human, mouse for FLRT1 (see all 8)
    OriGene ORF clones in mouse, rat for FLRT1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FLRT1 (NM_013280)
    Sino Biological Human cDNA Clone for FLRT1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FLRT1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FLRT1
    Sirion Biotech Customized lentivirus for stable overexpression of FLRT1 
                         Customized lentivirus expression plasmids for stable overexpression of FLRT1 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for FLRT1
    Search LifeMap BioReagents cell lines for FLRT1
    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FLRT1


    Pathways & Interactions
    for FLRT1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FLRT1

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for FLRT1 (Q9NZU12, 3 ENSP000002468414) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FLRT2O431552, 3, ENSP000003328794MINT-1778563 I2D: score=1 STRING: ENSP00000332879
    --Q70AK32MINT-1778419
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007155cell adhesion IEA--
    GO:0008150biological_process ND--

    FLRT1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for FLRT1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FLRT1

    Search CenterWatch for drugs/clinical trials and news about FLRT1

    Transcripts
    for FLRT1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for FLRT1 gene: 
    NM_013280.4  

    Unigene Cluster for FLRT1:

    Fibronectin leucine rich transmembrane protein 1
    Hs.584876  [show with all ESTs]
    Unigene Representative Sequence: AY358308
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000246841(uc001nyi.1)
    miRNA
    Products:             		 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FLRT1
    8 QIAGEN miScript miRNA Assays for microRNAs that regulate FLRT1:
    hsa-miR-502-5p hsa-miR-196a hsa-miR-544 hsa-miR-196b hsa-miR-654-3p hsa-miR-145 hsa-miR-205* hsa-miR-552
    SwitchGear 3'UTR luciferase reporter plasmid: FLRT1 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for FLRT1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FLRT1
    Clone
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    OriGene ORF clones in mouse, rat for FLRT1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FLRT1 (NM_013280)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FLRT1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FLRT1
    Sirion Biotech Customized lentivirus for stable overexpression of FLRT1 
                         Customized lentivirus expression plasmids for stable overexpression of FLRT1 
    Primer
    Products:            		OriGene qPCR primer pairs and template standards for FLRT1
    OriGene qSTAR qPCR primer pairs in human, mouse for FLRT1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FLRT1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FLRT1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FLRT1

    Additional mRNA sequence: 

    AF007139.1 AF169675.1 AK289931.1 AY358308.1 BC018370.1 

    3 DOTS entries:

    DT.97770464  DT.210792  DT.120741897 

    24/37 AceView cDNA sequences (see all 37):

    BX951900 AI494233 F04546 Z40799 BM710660 AI362924 BX090702 BU742770 
    BF437742 BM667377 Z45074 BM674096 CD624700 BF530310 BC018370 BM728867 
    F08324 AF169675 AF007139 BM715659 NM_013280 AY358308 CD624699 BG913718 

    GeneLoc Exon Structure


    Expression
    for FLRT1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FLRT1 expression in normal human tissues (normalized intensities)      FLRT1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAGTCGATTA
    FLRT1 Expression
    About this image


    FLRT1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Brain (Nervous System)    fully expand to see all 18 entries
             Thalamus
             Septum   
     
     Spinal Cord (Nervous System)    fully expand to see all 2 entries
             Dorsal Horn   

    See FLRT1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FLRT1

    SOURCE GeneReport for Unigene cluster: Hs.584876

    UniProtKB/Swiss-Prot: FLRT1_HUMAN, Q9NZU1
    Tissue specificity: Expressed in kidney and brain

        SABiosciences Custom PCR Arrays for FLRT1
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FLRT1

    Orthologs
    for FLRT1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for FLRT1 gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Flrt11 , 5 fibronectin leucine rich transmembrane protein 11, 5 89.27(n)1
    96.14(a)1    		   19 (5.20 cM)5
    3961841  NM_201411.21  NP_958813.11 
     70920145 
    lizard
    (Anolis carolinensis)    		 Reptilia FLRT16
    		 fibronectin leucine rich transmembrane protein 1
    		 87(a)
    		 1 ↔ 1
    		 GL343555.1(263570-311098)
    zebrafish
    (Danio rerio)    		 Actinopterygii flrt1a1 fibronectin leucine rich transmembrane 1a 60.86(n)
    63.61(a)    		   100144402  XM_003198722.1  XP_003198770.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Tollo6
    Toll-66
    (see all 5)    		 Toll-6
    (see all 5)    		 6(a)
    5(a)
    (see all 5)    		 possible ortholog
    possible ortholog
    (see all 5)    		 3L(15228719-15235932)
    3L(15329792-15337417)
    worm
    (Caenorhabditis elegans)    		 Secernentea tol-16
    lron-156
    (see all 7)    		 Protein LRON-15
    (see all 7)    		 8(a)
    7(a)
    (see all 7)    		 possible ortholog
    possible ortholog
    (see all 7)    		 I(443999-461607)
    II(6540217-6544892)


    ENSEMBL Gene Tree for FLRT1 (if available)
    TreeFam Gene Tree for FLRT1 (if available)

    Paralogs
    for FLRT1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FLRT1 gene
    PODN2  PODNL12  FMOD2  KERA2  PRELP2  FLRT32  OMD2  ASPN2  
    BGN2  DCN2  FLRT22  ECM22  LUM2  
    2 SIMAP similar genes for FLRT1 using alignment to 1 protein entry:     FLRT1_HUMAN:
    FLRT3    FLRT2

    FLRT1 for paralogs           About GeneDecksing



    Genomic Variants
    for FLRT1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section
    		Structural Variations
         Database of Genomic Variants (DGV) 9 variations for FLRT1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2744613CNV Deletion23290073
    dgv1155n71CNV Loss21882294
    nsv356CNV Loss18451855
    dgv15n68CNV Loss17160897
    dgv1156n71CNV Loss21882294
    dgv1163n71CNV Loss21882294
    dgv1160n71CNV Loss21882294
    nsv469961CNV Loss18288195
    dgv1162n71CNV Gain21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing FLRT1
    DNA2.0 Custom Variant and Variant Library Synthesis for FLRT1

    Disorders / Diseases
    for FLRT1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    FLRT1 for disorders           About MalaCards
    OMIM gene information: 604806    OMIM disorders: --


    FLRT1 for disorders           About GeneDecksing


    Export disorders for FLRT1 gene to outside databases

    Publications
    for FLRT1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FLRT1 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with FLRT1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of FLRT1, FLRT2, and FLRT3: a novel family of transmembrane leucine-rich repeat proteins. (PubMed id 10644439)1, 2, 3 Lacy S.E.... Kunkel L.M. (1999)
    2. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    3. Critical role of FLRT1 phosphorylation in the interde pendent regulation of FLRT1 function and FGF receptor signalling. (PubMed id 20421966)1, 9 Wheldon L.M....Heath J.K. (2010)
    4. Host-microbe interactions have shaped the genetic arch itecture of inflammatory bowel disease. (PubMed id 23128233)1 Jostins L....Cho J.H. (2012)
    5. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    9. Large-scale concatenation cDNA sequencing. (PubMed id 9110174)1 Yu W.... Gibbs R.A. (1997)
    10. A "double adaptor" method for improved shotgun library construction. (PubMed id 8619474)1 Andersson B.... Gibbs R.A. (1996)

    External Searches for FLRT1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    Genome Databases showing FLRT1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23769 HGNC: 3760 AceView: FLRT1 Ensembl:ENSG00000126500 euGenes: HUgn23769
    ECgene: FLRT1 H-InvDB: FLRT1

    Other Databases showing FLRT1 gene

    (According to HUGE)
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    Specialized Databases showing FLRT1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FLRT1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for FLRT1 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for FLRT1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for FLRT1 gene:
    Search GeneIP for patents involving FLRT1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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