Aliases for FLOT2 Gene
External Ids for FLOT2 Gene
Previous HGNC Symbols for FLOT2 Gene
Previous GeneCards Identifiers for FLOT2 Gene
Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. This gene encodes a caveolae-associated, integral membrane protein, which is thought to function in neuronal signaling. [provided by RefSeq, Jul 2008]
GeneCards Summary for FLOT2 Gene
FLOT2 (Flotillin 2) is a Protein Coding gene. Diseases associated with FLOT2 include toxic megacolon. Among its related pathways are Transmission across Chemical Synapses and Translation Insulin regulation of translation. GO annotations related to this gene include protease binding and ionotropic glutamate receptor binding. An important paralog of this gene is FLOT1.
UniProtKB/Swiss-Prot for FLOT2 Gene
May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.