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FLI1 Gene

protein-coding GIFtS: 69

GC11P128069

Friend leukemia virus integration 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
EWSR2 ^¹, ²
SIC-1 ^¹, ²

Descriptions
ERGB transcription factor ^³
Fli-1 proto-oncogene ^³
Friend leukemia virus integration 1 ^²

External Ids
HGNC: 3749¹
Entrez Gene: 2313²
UniProtKB: Q01543³
Ensembl: ENSG00000151702⁷

Search outside databases for aliases for FLI1 gene

Previous GC identifers: GC11P130564 GC11P130076 GC11P128596 GC11P128101

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: FLI1_HUMAN, Q01543

Function: Sequence-specific transcriptional activator. Recognizes the DNA sequence

5'-C[CA]GGAAGT-3'

Gene Wiki entry for FLI1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the FLI1 gene

Entrez Gene cytogenetic band: 11q24.1-q24.3 Ensembl cytogenetic band: 11q24.3 HGNC cytogenetic band: 11q24.1-q24.3

FLI1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11P128069: (about GC identifiers)

Start:	128,069,199 bp from pter
End:	128,187,521 bp from pter
Size:	118,323 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000011.8 NT_033899.7

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: FLI1_HUMAN, Q01543 (See protein sequence)

Recommended Name: Friend leukemia integration 1 transcription factor

Size: 452 amino acids; 50982 Da

Subunit: Can form homodimers or heterodimers with ETV6/TEL1

Subcellular location: Nucleus

Miscellaneous: Located on a fragment of chromosome 11 flanked on the centromeric side by the acute

lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation breakpoint and on the telomeric

side by the Ewing- and neuroepithelioma-associated t(11;22) (q24;q12) breakpoint

PDB structures from and Proteopedia :

1FLI (3D)

1X66 (3D)

2YTU (3D)

Secondary accessions: Q14319 Q92480 Q9UE07

Alternative splicing: 2 isoforms: Q01543-1 Q01543-2

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_002008.2

ENSEMBL proteins:

ENSP00000339627 ENSP00000281428

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (FLI1)
	Human Recombinant Proteins from Abnova (FLI1)

OriGene Purified Recombinant Human Protein: FLI1

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--

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Antibodies for FLI1:

	Invitrogen Antibodies for FLI1
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for FLI1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (FLI1), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Novus Biologicals Antibodies for FLI1

Assays for FLI1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry Q01543

ProtoNet protein and cluster: Q01543

1 Blocks protein family: IPB003118 Sterile alpha motif (SAM)/Pointed domain

UniProtKB/Swiss-Prot: FLI1_HUMAN, Q01543

Similarity: Belongs to the ETS family

Similarity: Contains 1 ETS DNA-binding domain

Similarity: Contains 1 PNT (pointed) domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (FLI1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (FLI1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002017

Applied Biosystems Silencer® siRNAs for FLI1

Sigma-Aldrich siRNA for FLI1

Sigma-Aldrich shRNA Panels and shRNA for FLI1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for FLI1
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_002017
Myc/DDK tagged cDNA clone in CMV expression vector: NM_002017
untagged cDNA clone in CMV expression vector: NM_002017

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_002017

UniProtKB/Swiss-Prot: FLI1_HUMAN, Q01543

Function: Sequence-specific transcriptional activator. Recognizes the DNA sequence

5'-C[CA]GGAAGT-3'

Genatlas biochemistry entry for FLI1:

Friend and Cas-Br-E murine leukemia virus integration site

9 MGI mutant phenotypes (inferred from 5 alleles) (MGI details for Fli1):

	embryogenesis	growth/size	hematopoietic system	immune system
lethality-prenatal/perinatal	liver/biliary system	nervous system	tumorigenesis

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003700	transcription factor activity	TAS	10891501
GO:0043565	sequence-specific DNA binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Gene Network Central^TM Interacting Genes and Proteins Network for FLI1

5/17 Interacting proteins for FLI1 (Q01543^{1, 2} ENSP00000339627³) via UniProtKB, MINT, and/or STRING (see all 17 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
Grip1 Grip1 (xeno)	Q925T6¹	EBI-2271018, EBI-537752
SMAD9	O15198²	MINT-61936 MINT-62072
EWSR1	ENSP00000330516³	STRING (score=.984)
EP300	ENSP00000263253³	STRING (score=.926)
CCND1	ENSP00000227507³	STRING (score=.911)

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4 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006350	transcription	IEA	--
GO:0006355	regulation of transcription, DNA-dependent	IEA	--
GO:0007599	hemostasis	TAS	10891501
GO:0009887	organ morphogenesis	TAS	10891501

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for FLI1
1 Novoseek chemical compound relationship for FLI1 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
oligonucleotide	0.00	1	8238248 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (FLI1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (FLI1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002017

Sigma-Aldrich siRNA for FLI1

Sigma-Aldrich shRNA Panels and shRNA for FLI1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_002017

REFSEQ mRNAs for FLI1 gene:

NM_002017.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_002017

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_002017
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_002017
                                 untagged cDNA clone in CMV expression vector: NM_002017

Additional cDNA sequence:

AK294279.1 AK300153.1 AK313370.1 AY029368.1 BC001670.1 BC010115.1 CR600005.1 M93255.1

M98833.3 S45205.1 S64709.1 S72620.1 X67001.1

6 DOTS entries:

DT.315565 DT.91981587 DT.207655 DT.91669639 DT.100665472 DT.99933688

24/132 AceView cDNA sequences (see all 132 ):

AW340324 AA256529 BF899604 AA863340 BQ215477 BC001670 BC010115 AU118654

BQ642921 AI457281 AI354789 CR600005 BG257780 BQ953977 BF224181 AI468916

BX281437 AA862270 AI216469 BQ232274 BX328036 AA805688 AA664465 AW965804

highest scoring ESTs for FLI1:

AA210631 AA234465 AA312319 AA805688 AA862270 AA917046 AI128180 AI273710 AI372049 AI376527

Unigene Cluster for FLI1:

Friend leukemia virus integration 1

Hs.504281 [show with all ESTs]

Unigene Representative Sequence: NM_002017

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for FLI1

ExUns:	1	^	2	^	3a	·	3b	^	4	^	5a	·	5b	^	6	^	7	^	8a	·	8b	^	9	^	10	^	11a	·	11b	·	11c
SP1:													-						-
SP2:									-				-						-
SP3:			-						-				-
SP4:
SP5:									-

About this scheme

ECgene alternative splicing isoforms for FLI1

2 Ensembl transcripts including schematic representations:

ENST00000344954 ENST00000281428

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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FLI1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for FLI1

¹ / ² / ³

9 probe-sets matching FLI1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
41425_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	M98833	0.80	1.00	0.91	1
204236_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_002017	0.40	1.00	0.76	1
210786_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	M93255	0.80	1.00	0.91	1
237722_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AW444915	0.40	1.00	0.76	1
211825_s_at²^{, 3}	U133-A	2	1.00	0.50	--	--	AF327066	0.20	0.33	0.27	2
204236_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
210786_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
237722_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
211825_s_at²	U133Plus2	2	1.00	0.50	--	--	--	--	--	--	--

GeneDecks FLI1 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TTGTAAAATA

SOURCE GeneReport for Unigene cluster: Hs.504281
Expression variation in blood from EXPOLDB for FLI1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for FLI1 gene from 5/11 species (see all 11 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	FLI1¹	--	Friend leukemia virus integration 1	92.54(n) 97.56(a)	489286 XM_851932.1 XP_857025.1
chimpanzee (Pan troglodytes)	FLI1¹	--	Friend leukemia virus integration 1	99.78(n) 100(a)	451659 XM_508856.2 XP_508856.2
cow (Bos taurus)	FLI1¹	--	Friend leukemia virus integration 1	91.89(n) 95.8(a)	529124 NM_001046298.1 NP_001039763.1
rat (Rattus norvegicus)	Fli1¹	--	Friend leukemia virus integration 1	90.86(n) 96.24(a)	315532 NM_001017381.1 NP_001017381.1
mouse (Mus musculus)	Fli1^{1, 5}	9 (16.00 cM)⁵	Friend leukemia integration 1^{1, 5}	90.93(n)¹ 96.68(a)¹	14247¹ NM_008026.3¹ NP_032052.1¹ AF275880⁵ AK036655⁵ (see all 13)

About this table Species with no ortholog for FLI1

ENSEMBL Gene Tree for FLI1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for FLI1 gene

FEV² ERG² ETV2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/843 NCBI SNPs in FLI1 are shown (see all 843 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 375)

AB	SNP ID	Valid	Chr 11 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs1148066^1,2	A,C,F,O	128187816(-)	`CAGACC/AAGTCT`	1	--	ut3¹		3		NA	142
	rs695113^1,2	A,C,F,H	128067308(-)	`TCCACA/GTGCTT`	1	--	ng5¹ tfbs³		8		EA MN EU WA	2280
	rs682695^1,2	A,F,H	128187670(-)	`ACAATG/TAAAAA`	1	--	ut3¹		5		MN EU EA WA	580
	rs7130622^1,2	F,H	128186721(+)	`TCTAGA/CAATAG`	1	--	ut3¹		4		EU EA WA	418
	rs12420823^1,2	A,C	128068602(+)	`CCTAGC/TCAACT`	1	--	ng5¹		0	--	--	--	--
	rs1053261^1,2	H	128185905(+)	`CTTCCT/CACCAT`	1	H/Y	mis¹		5		MN EU EA WA	590
	rs12420835^1,2	C	128068623(+)	`ACCCCA/CCCTAC`	1	--	ng5¹		0	--	--	--	--
	rs7113191^1,2	A,C,F	128180502(+)	`GGAGCT/ATGGGG`	1	A/A	syn¹		1		NA	74
	rs35195224^1,2	C,F	128157103(+)	`GACCAA/GTCCTC`	1	Q/Q	syn¹		1		NA	50
	rs603021^1,2	A,C,F,H,O	128149617(-)	`GGCCTG/ACCTAG`	1	--	int¹		5		EA EU WA	1896

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HapMap Linkage Disequilibrium images for FLI1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 193067

UniProtKB/Swiss-Prot: FLI1_HUMAN, Q01543

A chromosomal aberration involving FLI1 is a cause of Ewing sarcoma [MIM:133450].

Translocation t(11;22)(q24;q12) with EWS

10/32 Novoseek disease relationships for FLI1 gene (see all 32 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
ewings sarcoma	93.47	74	12522555 (4), 16837212 (3), 8039423 (3), 16865286 (2) (see all 55)
friend leukemia	82.15	4	15557108 (1), 18785112 (1), 1406633 (1), 8039423 (1)
peripheral neuroepithelioma	75.77	1	8039423 (1)
erythroleukemia	70.70	22	2044959 (4), 8502483 (4), 8336942 (2), 14570912 (1) (see all 13)
vascular neoplasms	65.20	6	15001993 (3), 11474291 (2)
neuroectodermal tumors	59.33	1	16046110 (1)
sarcoma synovial	57.70	1	11117787 (1)
rhabdomyosarcoma	51.81	2	11117787 (1), 16917000 (1)
leukemia	49.49	19	9178886 (2), 2044959 (2), 10772879 (2), 8336942 (2) (see all 14)
sarcoma	48.95	2	11474291 (1), 8336942 (1)

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1 PharmGKB disease relationship for FLI1 gene

Disease	PharmGKB Relations	PubMed IDs for articles supporting these relationships
Leukemia, Lymphocytic, Acute, L1	FA GN	12086872 12730115

About this table

Genetic Association Database: FLI1
Human Genome Epidemiology Navigator: FLI1 (1 document)
Tumor Gene Database: FLI1

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/200 PubMed articles for FLI1 gene (see all 200 ):

The human homolog of the mouse common viral integration region, FLI1, maps to 11q23-q24. (PubMed id 1765382)^{2, 3, 4} Baud V.... Bergeron D. (1991)
Solution structure of the ets domain of Fli-1 when bound to DNA. (PubMed id 7773776)^{1, 3, 4} Liang H.... Fesik S.W. (1994)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Chromosome translocation based on illegitimate recombination in human tumors. (PubMed id 9751743)^{3, 4} Zucman-Rossi J.... Thomas G. (1998)
Molecular analysis of a t(11;22) translocation junction in a case of Ewing's sarcoma. (PubMed id 7542907)^{3, 4} Bhagirath T.... Yoshida M.C. (1995)
Human FLI-1 localizes to chromosome 11q24 and has an aberrant transcript in neuroepithelioma. (PubMed id 8439553)^{3, 4} Hromas R....Klemsz M.J. (1993)
Structure and expression of human Fli-1 gene. (PubMed id 1394211)^{3, 4} Prasad D.D.... Reddy E.S. (1992)
The ERGB/Fli-1 gene: isolation and characterization of a new member of the family of human ETS transcription factors. (PubMed id 1445800)^{3, 4} Watson D.K.... Seth A. (1992)
Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours. (PubMed id 1522903)^{3, 4} Delattre O.... Thomas G. (1992)
FLI1 monoallelic expression combined with its hemizygous loss underlies Paris-Trousseau/Jacobsen thrombopenia. (PubMed id 15232614)^{1, 3} Raslova H....Favier R. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 2313	HGNC: 3749	AceView: FLI1	Ensembl:ENSG00000151702	euGenes: HUgn2313
ECgene: FLI1	H-InvDB: FLI1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
ATLAS Chromosomes in Cancer entry for FLI1	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for FLI1
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for FLI1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for FLI1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for FLI1		Antibodies for FLI1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for FLI1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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	Tagged/untagged cDNA clones
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	Purified proteins from HEK293T cells
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	shRNA in GFP-retroviral vector

Search Tocris compounds for FLI1

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for FLI1

GeneCards Homepage - Last full update: 1 Jul 2009 Incremental update: 13 Oct 2009

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FLI1 Gene

protein-coding GIFtS: 69

Aliases &
Descriptions
for FLI1

Summaries
for FLI1

Genomic Location
for FLI1

Proteins
for FLI1

Protein Domains/
Families
for FLI1

Gene Function
for FLI1

Pathways & Interactions
for FLI1

Drugs & Compounds
for FLI1

Transcripts
for FLI1

Expression
for FLI1

Orthologs
for FLI1

Paralogs
for FLI1

SNPs/Variants
for FLI1

Disorders & Mutations
for FLI1

Medical News
for FLI1

Publications
for FLI1

Search for FLI1

Genome Databases showing FLI1

Other Databases showing FLI1

Specialized Databases showing FLI1

Licensable Technologies
for FLI1

Services
for FLI1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

FLI1 Gene

protein-coding GIFtS: 69

Aliases & Descriptionsfor FLI1

Summariesfor FLI1

Genomic Locationfor FLI1

Proteinsfor FLI1

Protein Domains/Familiesfor FLI1

Gene Functionfor FLI1

Pathways & Interactionsfor FLI1

Drugs & Compoundsfor FLI1

Transcriptsfor FLI1

Expression for FLI1

Orthologsfor FLI1

Paralogsfor FLI1

SNPs/Variantsfor FLI1

Disorders & Mutationsfor FLI1

Medical Newsfor FLI1

Publicationsfor FLI1

Search for FLI1

Genome Databases showing FLI1

Other Databases showing FLI1

Specialized Databases showing FLI1

Licensable Technologiesfor FLI1

Servicesfor FLI1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for FLI1

Summaries
for FLI1

Genomic Location
for FLI1

Proteins
for FLI1

Protein Domains/
Families
for FLI1

Gene Function
for FLI1

Pathways & Interactions
for FLI1

Drugs & Compounds
for FLI1

Transcripts
for FLI1

Expression
for FLI1

Orthologs
for FLI1

Paralogs
for FLI1

SNPs/Variants
for FLI1

Disorders & Mutations
for FLI1

Medical News
for FLI1

Publications
for FLI1

Licensable Technologies
for FLI1

Services
for FLI1