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Aliases for FKBP9 Gene

Aliases for FKBP9 Gene

  • FK506 Binding Protein 9, 63 KDa 2 3
  • 63 KDa FK506-Binding Protein 3 4
  • FK506-Binding Protein 9 3 4
  • PPIase FKBP9 3 4
  • 63 KDa FKBP 3 4
  • EC 5.2.1.8 4 64
  • Rotamase 3 4
  • FKBP-63 3 4
  • FKBP-9 3 4
  • FKBP60 3 4
  • FKBP63 3 4
  • Peptidyl-Prolyl Cis-Trans Isomerase FKBP9 3
  • FK506-Binding Protein 9 (63 KD) 2
  • PPIASE 3

External Ids for FKBP9 Gene

Summaries for FKBP9 Gene

GeneCards Summary for FKBP9 Gene

FKBP9 (FK506 Binding Protein 9, 63 KDa) is a Protein Coding gene. Among its related pathways are Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein and Protein folding. GO annotations related to this gene include calcium ion binding and FK506 binding. An important paralog of this gene is FKBP7.

UniProtKB/Swiss-Prot for FKBP9 Gene

  • PPIases accelerate the folding of proteins during protein synthesis

Gene Wiki entry for FKBP9 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FKBP9 Gene

Genomics for FKBP9 Gene

Genomic Location for FKBP9 Gene

Start:
32,957,404 bp from pter
End:
33,006,931 bp from pter
Size:
49,528 bases
Orientation:
Plus strand

Genomic View for FKBP9 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FKBP9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FKBP9 Gene

Regulatory Elements for FKBP9 Gene

Proteins for FKBP9 Gene

  • Protein details for FKBP9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O95302-FKBP9_HUMAN
    Recommended name:
    Peptidyl-prolyl cis-trans isomerase FKBP9
    Protein Accession:
    O95302
    Secondary Accessions:
    • B3KY35
    • B7Z1G9
    • B7Z6H3
    • Q2M2A1
    • Q3MIR7
    • Q6IN76
    • Q6P2N1
    • Q96EX5
    • Q96IJ9

    Protein attributes for FKBP9 Gene

    Size:
    570 amino acids
    Molecular mass:
    63084 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FKBP9 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FKBP9 Gene

Proteomics data for FKBP9 Gene at MOPED

Selected DME Specific Peptides for FKBP9 Gene

Post-translational modifications for FKBP9 Gene

Other Protein References for FKBP9 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

Domains for FKBP9 Gene

Gene Families for FKBP9 Gene

HGNC:
  • EFHAND :EF-hand domain containing

Protein Domains for FKBP9 Gene

UniProtKB/Swiss-Prot:

FKBP9_HUMAN
Domain:
  • Contains 2 EF-hand domains.:
    • O95302
  • Contains 4 PPIase FKBP-type domains.:
    • O95302
genes like me logo Genes that share domains with FKBP9: view

Function for FKBP9 Gene

Molecular function for FKBP9 Gene

UniProtKB/Swiss-Prot CatalyticActivity: Peptidylproline (omega=180) = peptidylproline (omega=0)
UniProtKB/Swiss-Prot EnzymeRegulation: Inhibited by FK506.
UniProtKB/Swiss-Prot Function: PPIases accelerate the folding of proteins during protein synthesis

Enzyme Numbers (IUBMB) for FKBP9 Gene

Gene Ontology (GO) - Molecular Function for FKBP9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003755 peptidyl-prolyl cis-trans isomerase activity IBA --
GO:0005509 calcium ion binding ISS --
GO:0005528 FK506 binding IBA --
genes like me logo Genes that share ontologies with FKBP9: view

Phenotypes for FKBP9 Gene

MGI mutant phenotypes for FKBP9:
inferred from 1 alleles
GenomeRNAi human phenotypes for FKBP9:
genes like me logo Genes that share phenotypes with FKBP9: view

miRNA for FKBP9 Gene

miRTarBase miRNAs that target FKBP9

No data available for Animal Models , Transcription Factor Targeting and HOMER Transcription for FKBP9 Gene

Localization for FKBP9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for FKBP9 Gene

Endoplasmic reticulum.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FKBP9 Gene COMPARTMENTS Subcellular localization image for FKBP9 gene
Compartment Confidence
endoplasmic reticulum 4
cytoskeleton 1
cytosol 1
extracellular 1
golgi apparatus 1
mitochondrion 1
nucleus 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for FKBP9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum ISS --
GO:0005789 endoplasmic reticulum membrane IBA --
genes like me logo Genes that share ontologies with FKBP9: view

Pathways for FKBP9 Gene

genes like me logo Genes that share pathways with FKBP9: view

Interacting Proteins for FKBP9 Gene

Gene Ontology (GO) - Biological Process for FKBP9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000413 protein peptidyl-prolyl isomerization IBA --
GO:0006457 protein folding ISS --
GO:0061077 chaperone-mediated protein folding IBA --
genes like me logo Genes that share ontologies with FKBP9: view

Transcripts for FKBP9 Gene

Unigene Clusters for FKBP9 Gene

FK506 binding protein 9, 63 kDa:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FKBP9 Gene

No ASD Table

Relevant External Links for FKBP9 Gene

GeneLoc Exon Structure for
FKBP9
ECgene alternative splicing isoforms for
FKBP9

Expression for FKBP9 Gene

mRNA expression in normal human tissues for FKBP9 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FKBP9 Gene

SOURCE GeneReport for Unigene cluster for FKBP9 Gene Hs.103934

genes like me logo Genes that share expressions with FKBP9: view

Orthologs for FKBP9 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for FKBP9 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FKBP9 36
  • 99.77 (n)
  • 99.82 (a)
FKBP9 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FKBP9 36
  • 91.59 (n)
  • 97 (a)
FKBP9 37
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FKBP9 36
  • 91.55 (n)
  • 97.01 (a)
FKBP9 37
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fkbp9 36
  • 87.91 (n)
  • 93.13 (a)
Fkbp9 16
Fkbp9 37
  • 94 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FKBP9 37
  • 87 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FKBP9 37
  • 92 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fkbp9 36
  • 88.44 (n)
  • 94.19 (a)
chicken
(Gallus gallus)
Aves FKBP9 36
  • 76.81 (n)
  • 81.42 (a)
FKBP9 37
  • 78 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FKBP9 37
  • 81 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia fkbp9 36
  • 72.74 (n)
  • 78.64 (a)
Str.10967 36
zebrafish
(Danio rerio)
Actinopterygii fkbp9 36
  • 67.66 (n)
  • 68.6 (a)
fkbp9 37
  • 67 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG14715 37
  • 41 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea fkb-3 37
  • 33 (a)
ManyToMany
fkb-4 37
  • 31 (a)
ManyToMany
fkb-5 36
  • 47.42 (n)
  • 35.91 (a)
fkb-5 37
  • 31 (a)
ManyToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes FPR2 37
  • 39 (a)
OneToMany
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.12333 36
sea squirt
(Ciona savignyi)
Ascidiacea CSA.5986 37
  • 42 (a)
OneToMany
Species with no ortholog for FKBP9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FKBP9 Gene

ENSEMBL:
Gene Tree for FKBP9 (if available)
TreeFam:
Gene Tree for FKBP9 (if available)

Paralogs for FKBP9 Gene

Paralogs for FKBP9 Gene

Pseudogenes.org Pseudogenes for FKBP9 Gene

genes like me logo Genes that share paralogs with FKBP9: view

Variants for FKBP9 Gene

Sequence variations from dbSNP and Humsavar for FKBP9 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs10142 -- 33,006,585(+) CTGAG(C/T)ATCAA utr-variant-3-prime
rs10525 -- 33,005,784(+) ATTCT(A/T)GAGAT utr-variant-3-prime
rs1127604 -- 33,006,409(+) atgcc(C/T)agcca utr-variant-3-prime
rs1127607 -- 33,006,432(+) TTATT(C/T)CCACC utr-variant-3-prime
rs1127719 -- 33,006,906(+) CTTTT(C/T)TGATA utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for FKBP9 Gene

Variant ID Type Subtype PubMed ID
dgv1127e201 CNV Deletion 23290073
nsv436907 CNV Insertion 17901297
esv2734229 CNV Deletion 23290073
esv27091 CNV Gain+Loss 19812545

Relevant External Links for FKBP9 Gene

HapMap Linkage Disequilibrium report
FKBP9

Disorders for FKBP9 Gene

No disorders were found for FKBP9 Gene.

No data available for UniProtKB/Swiss-Prot for FKBP9 Gene

Publications for FKBP9 Gene

  1. Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. (PMID: 12754519) Zhang H. … Aebersold R. (Nat. Biotechnol. 2003) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Biochemical analysis of mouse FKBP60, a novel member of the FKBP family. (PMID: 10524204) Shadidy M. … Krauss S. (Biochim. Biophys. Acta 1999) 3 4
  4. Genomic organization of mouse and human 65 kDa FK506-binding protein genes and evolution of the FKBP multigene family. (PMID: 12036304) Patterson C.E. … Davis E.C. (Genomics 2002) 2 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for FKBP9 Gene

Sources for FKBP9 Gene

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