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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FKBP6 Gene

protein-coding   GIFtS: 60
GCID: GC07P072742

FK506 binding protein 6, 36kDa

(Previous name: FK506-binding protein 6 (36kD) )
 Explore 6 diseases affiliated with
FKBP6 via our new
 Human Malady Compendium 
Biological research products
for FKBP6
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
FK506 Binding Protein 6, 36kDa1 2     PPIase FKBP62 3
FKBP361 2 3     FK506-Binding Protein 6 (36kD)1
PPIase1 2     Peptidyl-Prolyl Cis-Trans Isomerase FKBP62
Immunophilin FKBP362 3     Rotamase3
36 KDa FK506-Binding Protein2 3     EC 5.2.1.83
36 KDa FKBP2 3     FKBP-63
FKBP-362 3     Rotamase3
FK506-Binding Protein 62 3     

External Ids:    HGNC: 37221   Entrez Gene: 84682   Ensembl: ENSG000000778007   OMIM: 6048395   UniProtKB: O753443   

Export aliases for FKBP6 gene to outside databases

Previous GC identifers: GC07P071382 GC07P072140 GC07P072154 GC07P071886 GC07P072078 GC07P072380 GC07P068623


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FKBP6:
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation
and basic cellular processes involving protein folding and trafficking. The protein may have cis-trans prolyl
isomerase activity, and binds to clathrin heavy chain and heat shock protein 72. This gene is found to be deleted in
Williams syndrome, and the orthologous gene in mouse is essential for fertility and homologous pairing in male
meiosis. (provided by RefSeq, Sep 2008)

UniProtKB/Swiss-Prot: FKBP6_HUMAN, O75344
Function: PPIases accelerate the folding of proteins




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.1  NT_007933.15  NT_079593.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FKBP6 gene promoter:
         STAT1   STAT2   STAT1beta   ITF-2   Tal-1beta   STAT1alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): FKBP6 promoter sequence
   Search SABiosciences Chromatin IP Primers for FKBP6

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FKBP6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q11.23   Ensembl cytogenetic band:  7q11.23   HGNC cytogenetic band: 7q11.23

FKBP6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FKBP6 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P072742:  view genomic region     (about GC identifiers)

Start:
72,742,155 bp from pter      End:
72,772,641 bp from pter
Size:
30,487 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 72,075,227-72,105,713     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: FKBP6_HUMAN, O75344 (See protein sequence)
Recommended Name: Peptidyl-prolyl cis-trans isomerase FKBP6  
Size: 327 amino acids; 37214 Da
1 PDB 3D structure from and Proteopedia for FKBP6:
3B7X (3D)    
Secondary accessions: B4DXT7 Q9UDS0
Alternative splicing: 2 isoforms:  O75344-1   O75344-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FKBP6: NX_O75344

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O75344

  • FKBP6 Protein expression data from MOPED and PaxDb:    About this image 
    FKBP6 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001128683.1  NP_003593.3  

    ENSEMBL proteins: 
     ENSP00000416277   ENSP00000402360   ENSP00000394952   ENSP00000415891   ENSP00000403908  
     ENSP00000252037  
    Reactome Protein details: O75344
    Human Recombinant Protein Products for FKBP6: 
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    Novus Biologicals FKBP6 Proteins
    Novus Biologicals FKBP6 Lysate
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    ProSpec Recombinant Protein for FKBP6
    Uscn Proteins for FKBP6

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016020membrane IBA--

    FKBP6 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    FKBP6 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR011990 TPR-like_helical
     IPR023566 PPIase_FKBP
     IPR001179 PPIase_FKBP_dom
     IPR013026 TPR-contain_dom

    Graphical View of Domain Structure for InterPro Entry O75344

    ProtoNet protein and cluster: O75344

    UniProtKB/Swiss-Prot: FKBP6_HUMAN, O75344
    Similarity: Contains 1 PPIase FKBP-type domain
    Similarity: Contains 3 TPR repeats


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FKBP6_HUMAN, O75344
    Function: PPIases accelerate the folding of proteins
    Catalytic activity: Peptidylproline (omega=180) = peptidylproline (omega=0)

         Genatlas biochemistry entry for FKBP6:
    FK506-binding protein6,T cell binding protein FKBP for the immunosuppressive agents FK506-rapamycin expressed in
    testis,heart,skeletal muscle,liver and kidney,deleted in Williams syndrome

         Enzyme Number (IUBMB): EC 5.2.1.81

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003755peptidyl-prolyl cis-trans isomerase activity IBA--
    GO:0005528FK506 binding IBA--
         
    FKBP6 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for FKBP6:
     Increased cell number in G1, s 

         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Fkbp6):
     endocrine/exocrine gland  reproductive system 

    FKBP6 for phenotypes           About GeneDecksing

    Animal Models:
         Mouse knock-out Fkbp6tm1Pngr for FKBP6
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for FKBP6 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FKBP6
    8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate FKBP6 (see all 10):
    hsa-miR-222* hsa-miR-199b-3p hsa-miR-199a-3p hsa-miR-3065-5p hsa-miR-3129-5p hsa-miR-548o hsa-miR-570 hsa-miR-1323
    SwitchGear 3'UTR luciferase reporter plasmidFKBP6 3' UTR sequence
    Inhib. RNA
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FKBP6


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Meiotic Synapsis
    Meiotic Synapsis1.00
    Chromosome Maintenance0.56
    Meiosis0.70
    2Synapsis
    Synapsis1.00
    3Cell Cycle
    Cell Cycle1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5        Reactome Pathways for FKBP6
        Synapsis
    Meiotic Synapsis
    Cell Cycle
    Meiosis
    Chromosome Maintenance



    FKBP6 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FKBP6

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    5/11 Interacting proteins for FKBP6 (O753442, 3 ENSP000002520374) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCNKO759092, 3, ENSP000003745294MINT-66761 I2D: score=5 STRING: ENSP00000374529
    NME7Q9Y5B82, 3, ENSP000003567854MINT-66560 I2D: score=5 STRING: ENSP00000356785
    GAPDHP044063, ENSP000002292394I2D: score=1 STRING: ENSP00000229239
    HSP90AA1P079003, ENSP000003351534I2D: score=1 STRING: ENSP00000335153
    TBC1D17Q9HA653I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000239pachytene IEA--
    GO:0000413protein peptidyl-prolyl isomerization ----
    GO:0006457protein folding IEA--
    GO:0007283spermatogenesis IEA--
    GO:0018208peptidyl-proline modification IBA--

    FKBP6 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Compounds for FKBP6 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    AscomycinCalcineurin phosphatase inhibitor; analog of FK 506 (Cat. No. 3631)[104987-12-4]
    Search CenterWatch for drugs/clinical trials and news about FKBP6 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for FKBP6 gene (2 alternative transcripts): 
    NM_001135211.1  NM_003602.3  

    Unigene Cluster for FKBP6:

    FK506 binding protein 6, 36kDa
    Hs.661266  [show with all ESTs]
    Unigene Representative Sequence: NM_003602
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000431982(uc011kew.1) ENST00000442793 ENST00000413573(uc003twz.2)
    ENST00000445032(uc003tya.2) ENST00000429879(uc010lbe.1) ENST00000437013
    ENST00000252037

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    hsa-miR-222* hsa-miR-199b-3p hsa-miR-199a-3p hsa-miR-3065-5p hsa-miR-3129-5p hsa-miR-548o hsa-miR-570 hsa-miR-1323
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    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FKBP6
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    Additional cDNA sequence: 

    AF038847.1 AK302121.1 AK310255.1 BC036817.1 

    6 DOTS entries:

    DT.309473  DT.101981340  DT.91685900  DT.95255279  DT.97774787  DT.97783554 

    22 AceView cDNA sequences:

    BG720247 AA077532 BV176079 AA446529 BI825663 BC022013 AI190559 BM981791 
    BV176436 AA078495 BG722503 AA843562 AI184590 BV176501 AA078227 BC067783 
    AA446348 AI873214 AW118983 BF870204 BU853536 AA078005 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FKBP6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GACGCGGCTG
    FKBP6 Expression
    About this image
    See FKBP6 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FKBP6

    SOURCE GeneReport for Unigene cluster: Hs.661266

    UniProtKB/Swiss-Prot: FKBP6_HUMAN, O75344
    Tissue specificity: Detected in all tissues examined, with higher expression in testis, heart, skeletal muscle, liver,
    and kidney

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for FKBP6 gene from 7/21 species (see all 21)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves FKBP61 FK506 binding protein 6, 36kDa 65.54(n)
    63.64(a)
      417460  XM_415708.3  XP_415708.3 
    lizard
    (Anolis carolinensis)
    Reptilia FKBP66
    --
    63(a)
    1 ↔ 1
    5(63500210-63515013)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.195292 Xenopus laevis transcribed sequence with weak similarity more 72.94(n)    BJ028858.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.265962 Danio rerio cDNA clone IMAGE5411885, partial cds 72.92(n)    BC054673.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta shu1 shutdown 44.56(n)
    29.97(a)
      45360  NM_137993.3  NP_611837.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons ATFKBP426
    PAS16
    peptidyl-prolyl isomerase PASTICCINO1
    20(a)
    11(a)
    1 ↔ many
    1 ↔ many
    3(7618930-7621477)
    3(20000861-20005183)
    rice
    (Oryza sativa)
    Liliopsida --
    --
    (see all 3)
    peptidyl-prolyl isomerase, putative, expressed
    (see all 3)
    18(a)
    18(a)
    (see all 3)
    1 ↔ many
    1 ↔ many
    (see all 3)
    11(2225663-2229801)
    12(2235009-2238463)


    ENSEMBL Gene Tree for FKBP6 (if available)
    TreeFam Gene Tree for FKBP6 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FKBP6 gene
    FKBP52  FKBP1A2  FKBP42  FKBP1C2  FKBP82  FKBP1B2  FKBP32  
    5 SIMAP similar genes for FKBP6 using alignment to 5 protein entries:     FKBP6_HUMAN (see all proteins):
    FKBP1C    FKBP1A    FKBP12-Exip2    FKBP1B    FKBP10

    FKBP6 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for FKBP6
    PGOHUM00000250883 PGOHUM00000250942


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/536 NCBI SNPs in FKBP6 are shown (see all 536    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs607990751,2
    C--72074155(+) GCCACC/TGCGCC 2 -- us2k11Minor allele frequency- T:0.50WA 2
    rs24632871,2
    --72074626(+) AAGAGA/GGAAAG 2 -- us2k1 trp30--------
    rs26953681,2
    --72074966(+) CTCTCA/GTTACG 2 -- us2k10--------
    rs26953691,2
    --72075080(+) CCCCAC/TGTCCG 2 -- us2k10--------
    rs21780221,2
    --72075276(+) TCGCAA/CCTCAC 2 -- ut51 us2k10--------
    rs26953701,2
    --72075447(+) CCAGGA/GAGGGC 2 -- int1 ut51 ese30--------
    rs77972421,2
    C--72076373(+) AGACTC/TGATAT 2 -- int10--------
    rs40309801,2
    C--72077173(+) TAGCAC/TTGAGC 2 -- int12Minor allele frequency- T:0.00NA 4
    rs39503761,2
    --72077267(+) CATGCA/GGAGAG 4 Q R mis1 ese3 trp30--------
    rs10641971,2
    --72077327(+) GGGCTG/CCCCTC 4 /S /C mis1 ese32Minor allele frequency- C:0.00NA 4

    HapMap Linkage Disequilibrium report for FKBP6 (72742155 - 72772641 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for FKBP6
         3 CNVs: 2699 3685 8567
    Human Gene Mutation Database (HGMD): FKBP6

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    FKBP6 for disorders           About GeneDecksing

    OMIM gene information: 604839    OMIM disorders: --

    UniProtKB/Swiss-Prot: FKBP6_HUMAN, O75344
  • Note=FKBP6 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous
  • deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between
    highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of FKBP6 may be the cause
    of certain cardiovascular and musculo-skeletal abnormalities observed in the disease

    6 diseases for FKBP6:    About MalaCards
    williams syndrome    williams-beuren syndrome    aortic valve stenosis    azoospermia
    infertility    esophagitis

    1 disease from the University of Copenhagen DISEASES database for FKBP6:
    Azoospermia

    2 Novoseek disease relationships for FKBP6 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    williams syndrome 80 1 15770126 (1)
    azoospermia 72 2 15516791 (1), 16983454 (1)

    Genetic Association Database (GAD): FKBP6
    Human Genome Epidemiology (HuGE) Navigator: FKBP6 (5 documents)

    Export disorders for FKBP6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FKBP6 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with FKBP6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel human gene FKBP6 is deleted in Williams syndrome. (PubMed id 9782077)1, 2, 3, 9 Meng X.... Keating M.T. (1998)
    2. Mutations in the chromosome pairing gene FKBP6 are not a common cause of non-obstructive azoospermia. (PubMed id 16227348)1, 4, 9 Westerveld G.H....van der Veen F. (2005)
    3. FKBP36 Is an Inherent Multifunctional Glyceraldehyde-3-phosphate Dehydrogenase Inhibitor. (PubMed id 19001379)1, 3 Jarczowski F....Edlich F. (2009)
    4. [Possible association between 278C/A single nucleotide polymorphism of FKBP6 and idiopathic azoospermia] (PubMed id 15696470)1, 4 Zhang W....Shi J.J. (2005)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Is a genetic defect in Fkbp6 a common cause of azoospermia in humans? (PubMed id 16983454)1, 9 Miyamato T....Sengoku K. (2006)
    7. Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients. (PubMed id 22610502)1 Kennedy R.B....Poland G.A. (2012)
    8. Genome-wide YFP fluorescence complementation screen id entifies new regulators for telomere signaling in human cells. (PubMed id 21044950)1 Lee O.H....Songyang Z. (2011)
    9. Evaluation of 172 candidate polymorphisms for associa tion with oligozoospermia or azoospermia in a large cohort of men of European d escent. (PubMed id 20378615)1 Aston K.I....Carrell D.T. (2010)
    10. FKBP36 forms complexes with clathrin and Hsp72 in spermatocytes. (PubMed id 18529014)1 Jarczowski F....Edlich F. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8468 HGNC: 3722 AceView: FKBP6.2 Ensembl:ENSG00000077800 euGenes: HUgn8468
    ECgene: FKBP6 H-InvDB: FKBP6

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FKBP6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for FKBP6 gene:
    Search GeneIP for patents involving FKBP6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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