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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FKBP10 Gene

protein-coding   GIFtS: 54
GCID: GC17P039968

FK506 binding protein 10, 65 kDa

(Previous name: FK506 binding protein 10 (65 kDa) )
 Explore 9 diseases affiliated with
FKBP10 via our new
 Human Malady Compendium 
Biological research products
for FKBP10
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
FK506 Binding Protein 10, 65 KDa1 2     OI62 5
FKBP652 3 5     FKBP61
HFKBP651     FLJ206831
Immunophilin FKBP652 3     FLJ220411
65 KDa FK506-Binding Protein2 3     FLJ238331
65 KDa FKBP2 3     FK506 Binding Protein 10 (65 KDa)1
FKBP-102 3     OI112
FKBP-652 3     PPIASE2
FK506-Binding Protein 102 3     Peptidyl-Prolyl Cis-Trans Isomerase FKBP102
PPIase FKBP102 3     Rotamase3
EC 5.2.1.83 8     Rotamase3

External Ids:    HGNC: 181691   Entrez Gene: 606812   Ensembl: ENSG000001417567   OMIM: 6070635   UniProtKB: Q96AY33   

Export aliases for FKBP10 gene to outside databases

Previous GC identifers: GC17P039525 GC17P042056 GC17P039877 GC17P040342 GC17P037222 GC17P035730


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FKBP10:
The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. This
protein localizes to the endoplasmic reticulum and acts as a molecular chaperone. Alternatively spliced variants
encoding different isoforms have been reported, but their biological validity has not been determined.(provided by
RefSeq, Nov 2009)

UniProtKB/Swiss-Prot: FKB10_HUMAN, Q96AY3
Function: PPIases accelerate the folding of proteins during protein synthesis

Gene Wiki entry for FKBP10


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010783.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FKBP10 gene promoter:
         AREB6   PPAR-gamma1   NRSF form 1   HOXA5   XBP-1   PPAR-gamma2   NRSF form 2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFKBP10 promoter sequence
   Search SABiosciences Chromatin IP Primers for FKBP10

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FKBP10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.2   Ensembl cytogenetic band:  17q21.2   HGNC cytogenetic band: 17q21.2

FKBP10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FKBP10 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P039968:  view genomic region     (about GC identifiers)

Start:
39,968,932 bp from pter      End:
39,979,469 bp from pter
Size:
10,538 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: FKB10_HUMAN, Q96AY3 (See protein sequence)
Recommended Name: Peptidyl-prolyl cis-trans isomerase FKBP10 precursor  
Size: 582 amino acids; 64245 Da
Subcellular location: Endoplasmic reticulum lumen (By similarity)
Sequence caution: Sequence=BAB15220.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=CAD97695.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: Q7Z3R4 Q9H3N3 Q9H6N5 Q9UF89

Explore the universe of human proteins at neXtProt for FKBP10: NX_Q96AY3

Post-translational modifications:

  • Glycosylated and phosphorylated (By similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q96AY3

  • 4/8 DME Specific Peptides for FKBP10 (Q96AY3) (see all 8)
     DFVRYHY  RYHYNGT  GKKFDSS  PPHLGYG 

    FKBP10 Protein expression data from MOPED and PaxDb:    About this image 
    FKBP10 Protein Expression
    REFSEQ proteins: NP_068758.3  
    ENSEMBL proteins: 
     ENSP00000468703   ENSP00000466097   ENSP00000269598   ENSP00000408232   ENSP00000317232  
     ENSP00000466352   ENSP00000416822   ENSP00000442009  

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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for FKBP10

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005788endoplasmic reticulum lumen IEA--
    GO:0016020membrane IBA--

    FKBP10 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    FKBP10 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR011992 EF-hand-like_dom
     IPR002048 EF_hand_Ca-bd
     IPR023566 PPIase_FKBP
     IPR018247 EF_Hand_1_Ca_BS
     IPR001179 PPIase_FKBP_dom

    Graphical View of Domain Structure for InterPro Entry Q96AY3

    ProtoNet protein and cluster: Q96AY3

    UniProtKB/Swiss-Prot: FKB10_HUMAN, Q96AY3
    Similarity: Contains 2 EF-hand domains
    Similarity: Contains 4 PPIase FKBP-type domains


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FKB10_HUMAN, Q96AY3
    Function: PPIases accelerate the folding of proteins during protein synthesis
    Catalytic activity: Peptidylproline (omega=180) = peptidylproline (omega=0)
    Enzyme regulation: Inhibited by both FK506 and rapamycin, but not by cyclosporin A (By similarity)

         Enzyme Number (IUBMB): EC 5.2.1.81 2

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003755peptidyl-prolyl cis-trans isomerase activity IBA--
    GO:0005509calcium ion binding IEA--
    GO:0005515protein binding ----
    GO:0005528FK506 binding IBA--
         
    FKBP10 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for FKBP10:
     Decreased Wnt reporter activit 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Fkbp10):
     limbs/digits/tail 

    FKBP10 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for FKBP10 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FKBP10


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for FKBP10

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5 Interacting proteins for FKBP10 (Q96AY33 ENSP000003172324) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SLX1AQ9BQ833, ENSP000002513034I2D: score=2 STRING: ENSP00000251303
    SLX1BQ9BQ833, ENSP000003289404I2D: score=2 STRING: ENSP00000328940
    H2AFXP161043, ENSP000003643104I2D: score=2 STRING: ENSP00000364310
    ELNP155023, ENSP000002520344I2D: score=1 STRING: ENSP00000252034
    SLC2A4P146723I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000413protein peptidyl-prolyl isomerization IBA--
    GO:0006457protein folding IEA--
    GO:0018208peptidyl-proline modification IBA--

    FKBP10 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Compounds for FKBP10 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    AscomycinCalcineurin phosphatase inhibitor; analog of FK 506 (Cat. No. 3631)[104987-12-4]
    Search CenterWatch for drugs/clinical trials and news about FKBP10 / FKB10 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for FKBP10 gene: 
    NM_021939.3  

    Unigene Cluster for FKBP10:

    FK506 binding protein 10, 65 kDa
    Hs.463035  [show with all ESTs]
    Unigene Representative Sequence: NM_021939
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000585664 ENST00000585922 ENST00000269598 ENST00000429461 ENST00000321562(uc002hxv.2)
    ENST00000489591(uc002hxw.1) ENST00000487489 ENST00000455106 ENST00000490938
    ENST00000464180 ENST00000544340

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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FKBP10
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    hsa-miR-98 hsa-let-7d hsa-miR-922 hsa-let-7c hsa-let-7i hsa-let-7g hsa-let-7e hsa-let-7b
    SwitchGear 3'UTR luciferase reporter plasmidFKBP10 3' UTR sequence
    Inhib. RNA
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    Additional cDNA sequence: 

    AB045981.1 AF337909.1 AK000690.1 AK025694.1 AK025874.1 AK074413.1 AK092708.1 AK172811.1 
    AK296107.1 AL365371.1 AL832985.1 BC016467.1 BX537452.1 

    22 DOTS entries:

    DT.40226864  DT.97820313  DT.444006  DT.100814514  DT.100814519  DT.100814511  DT.95095089  DT.100679290 
    DT.100814507  DT.91761823  DT.95095087  DT.91896046  DT.100814518  DT.102833617  DT.40118629  DT.99933402 
    DT.99970961  DT.100814509  DT.120956059  DT.120956076  DT.120956094  DT.97847562 

    24/353 AceView cDNA sequences (see all 353):

    BQ900731 AI802295 BM726246 AW513548 AI349417 AL520008 AL555653 BP373508 
    CB141440 BU147280 CF131880 CD630953 BX446435 BM817681 BQ219766 AW074526 
    AL522678 BP372132 T09475 CR606502 CK904106 BM556017 BX459074 BP365162 

    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for FKBP10 (see all 12)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b ^ 14 ^ 15a · 15b ^ 16a ·
    SP1:                                                                    -                       -     -     -     -           -                                 
    SP2:                                      -     -                       -                                         -           -                                 
    SP3:                                                                                            -           -     -           -                                 
    SP4:        -     -     -                                                                                                                                       
    SP5:                                                                                                                                                            

    ExUns: 16b · 16c ^ 17
    SP1:                  
    SP2:                  
    SP3:                  
    SP4:                  
    SP5:                  


    ECgene alternative splicing isoforms for FKBP10

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FKBP10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TGTGAGGGAA
    FKBP10 Expression
    About this image
    See FKBP10 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FKBP10

    SOURCE GeneReport for Unigene cluster: Hs.463035
        SABiosciences Custom PCR Arrays for FKBP10

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FKBP10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for FKBP10 gene from 6/21 species (see all 21)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves LOC4270131 peptidyl-prolyl cis-trans isomerase FKBP10-like 77.66(n)
    79.6(a)
      427013  XM_003642830.1  XP_003642878.1 
    lizard
    (Anolis carolinensis)
    Reptilia FKBP106
    --
    74(a)
    1 ↔ 1
    6(66594841-66616687)
    African clawed frog
    (Xenopus laevis)
    Amphibia LOC3981752 FK506-binding protein 75.89(n)    AF232672.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.32122 Danio rerio, Similar to FK506 binding protein 10 (65 more 71.98(n)    BC045938.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons FKBP16-26
    ATFKBP136
    FKBP-type peptidyl-prolyl cis-trans isomerase 3
    20(a)
    18(a)
    possible ortholog
    possible ortholog
    4(18427039-18428412)
    5(18530880-18532337)
    rice
    (Oryza sativa)
    Liliopsida --
    --
    peptidyl-prolyl cis-trans isomerase, FKBP-type, pu...
    peptidyl-prolyl cis-trans isomerase, FKBP-type, pu...
    17(a)
    16(a)
    possible ortholog
    possible ortholog
    6(27401365-27402771)
    2(31585352-31587283)


    ENSEMBL Gene Tree for FKBP10 (if available)
    TreeFam Gene Tree for FKBP10 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FKBP10 gene
    FKBP112  FKBP22  FKBP142  FKBP72  FKBP92  
    13 SIMAP similar genes for FKBP10 using alignment to 8 protein entries:     FKB10_HUMAN (see all proteins):
    DKFZp666D193    FKBP9L    FKBP9    FKBP2    FKBP11    FKBP7
    FKBP12-Exip2    FKBP14    FKBP1B    FKBP1C    FKBP1A    FKBP4
    FKBP6

    FKBP10 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for FKBP10
    PGOHUM00000232700


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/211 NCBI SNPs in FKBP10 are shown (see all 211    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs72086191,2
    C,Huntested38588833(+) AGGACA/TCTGTC 2 T syn1 ese34Minor allele frequency- T:0.00NS EA 416
    rs80787751,2
    C,F,A,Huntested38589976(+) GGGACA/GGTGAT 2 T syn1 ese39Minor allele frequency- G:0.02NS EA NA WA CSA 5164
    rs347647491,2
    C,Funtested38590803(+) CAGTAA/GGGGCG 2 K R mis113Minor allele frequency- G:0.06NA NS EA CSA WA EU 6734
    rs2012347511,2
    C--35732705(-) GCTGGA/GGGACT 1 -- int10--------
    rs1421694521,2
    C--35733005(+) TTTTT-/TAGCTG 1 -- int10--------
    rs608066031,2
    C--35733510(+) AGCCTT/CGTGAT 1 -- int12Minor allele frequency- C:0.25WA CSA 4
    rs1133026871,2
    C--35733843(+) CCTCCT/CGATTA 1 -- int12Minor allele frequency- C:0.25WA CSA 4
    rs1115441451,2
    C--35734041(+) CAATT-/AAAAAA 1 -- int11Minor allele frequency- A:0.50CSA 2
    rs1503139491,2
    C--35735319(+) ATGATC/TGCAAC 2 R C mis11Minor allele frequency- T:0.00NA 4550
    rs711551711,2
    C--35735890(-) GTCTCA/-AAAAA 1 -- int11Minor allele frequency- -:0.00NA 2

    HapMap Linkage Disequilibrium report for FKBP10 (39968932 - 39979469 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for FKBP10: --
    Human Gene Mutation Database (HGMD): FKBP10

    Locus Specific Mutation Databases (LSDB): FKBP10

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    FKBP10 for disorders           About GeneDecksing

    OMIM gene information: 607063   
    OMIM disorders: 610698  
    UniProtKB/Swiss-Prot: FKB10_HUMAN, Q96AY3
  • Defects in FKBP10 are the cause of osteogenesis imperfecta type 6 (OI6) [MIM:610968]. OI6 is a moderate to
  • severe, autosomal recessive form of osteogenesis imperfecta characterized by increased serum alkaline phosphatase
    levels and bone histology exhibiting a fish scale-like lamellar pattern. Osteogenesis imperfecta defines a group of
    connective tissue disorders characterized by bone fragility and low bone mass

    9 diseases for FKBP10:    About MalaCards
    osteogenesis imperfecta    osteogenesis imperfecta type 6    dentinogenesis imperfecta    bruck syndrome
    epithelial ovarian cancer    benign tumors    ovarian cancer    hepatocellular carcinoma
    carcinoma

    2 diseases from the University of Copenhagen DISEASES database for FKBP10:
    Osteogenesis imperfecta     Dentinogenesis imperfecta

    Export disorders for FKBP10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FKBP10 gene, integrated from 9 sources (see all 29):
    (articles sorted by number of sources associating them with FKBP10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The rough endoplasmic reticulum-resident FK506-binding protein FKBP65 is a molecular chaperone that interacts with collagens. (PubMed id 18786928)1, 3, 9 Ishikawa Y....Bachinger H.P. (2008)
    2. Mutations in the gene encoding the RER protein FKBP65 cause autosomal-recessive osteogenesis imperfecta. (PubMed id 20362275)1, 2 Alanay Y....Krakow D. (2010)
    3. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. (PubMed id 12754519)1, 2 Zhang H.... Aebersold R. (2003)
    7. Developmental regulation of FKBP65. An ER-localized extracellular matrix binding-protein. (PubMed id 11071917)1, 3 Patterson C.E....Davis E.C. (2000)
    8. Developmental regulation and coordinate reexpression of FKBP65 with extracellular matrix proteins after lung injury suggest a specialized function for this endoplasmic reticulum immunophilin. (PubMed id 16333983)1, 9 Patterson C.E....Davis E.C. (2005)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    10. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 60681 HGNC: 18169 AceView: FKBP10 Ensembl:ENSG00000141756 euGenes: HUgn60681
    ECgene: FKBP10 H-InvDB: FKBP10

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FKBP10 Pharmacogenomics, SNPs, Pathways
    Osteogenesis imperfecta variant databasehttp://oi.gene.le.ac.uk/home.php?select_db=FKBP10

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for FKBP10 gene:
    Search GeneIP for patents involving FKBP10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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