Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



FIZ1 Gene

protein-coding   GIFtS: 49
GCID: GC19M056102

FLT3-Interacting Zinc Finger 1

  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
FLT3-Interacting Zinc Finger 11 2
Zinc Finger Protein 7982 3
ZNF7982 3
Flt3-Interacting Zinc Finger Protein 12

External Ids:    HGNC: 259171   Entrez Gene: 849222   Ensembl: ENSG000001799437   OMIM: 6091335   UniProtKB: Q96SL83   

Export aliases for FIZ1 gene to outside databases

Previous GC identifers: GC19M060795 GC19M052413


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for FIZ1 Gene:
This gene encodes zinc finger protein, which interacts with a receptor tyrosine kinase involved in the regulation
of hematopoietic and lymphoid cells. This gene product also interacts with a transcription factor that regulates
the expression of rod-specific genes in retina. (provided by RefSeq, Jul 2008)

GeneCards Summary for FIZ1 Gene:
FIZ1 (FLT3-interacting zinc finger 1) is a protein-coding gene. GO annotations related to this gene include protein kinase binding and nucleic acid binding.

UniProtKB/Swiss-Prot: FIZ1_HUMAN, Q96SL8
Function: May be a transcriptional repressor of NRL function in photoreceptors. Does not repress CRX-mediated
transactivation (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NT_011109.17  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the FIZ1 gene promoter:
         STAT5B   RP58   MAZR   Pax-5   p53   NF-kappaB   HEN1   E2F-1   E2F   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFIZ1 promoter sequence
   Search Chromatin IP Primers for FIZ1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FIZ1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.42   Ensembl cytogenetic band:  19q13.42   HGNC cytogenetic band: 19q13.42

FIZ1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FIZ1 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M056102:  view genomic region     (about GC identifiers)

Start:
56,102,737 bp from pter      End:
56,113,336 bp from pter
Size:
10,600 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: FIZ1_HUMAN, Q96SL8 (See protein sequence)
Recommended Name: Flt3-interacting zinc finger protein 1  
Size: 496 amino acids; 51996 Da
Subunit: Interacts with FLT3 cytoplasmic catalytic domain, following receptor stimulation, in a kinase-independent
manner. Does not interact with other structurally related receptor tyrosine kinases, including KIT, CSF1R and
PDGFR. Interacts with NRL (By similarity)
Sequence caution: Sequence=BAD18728.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A2RU72 Q6ZMJ7

Explore the universe of human proteins at neXtProt for FIZ1: NX_Q96SL8

Explore proteomics data for FIZ1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See FIZ1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_116225.2  
    ENSEMBL proteins: 
     ENSP00000221665   ENSP00000465131   ENSP00000468529   ENSP00000468342   ENSP00000468018  

    FIZ1 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for FIZ1
    OriGene Protein Over-expression Lysate for FIZ1
    OriGene MassSpec for FIZ1
    OriGene Custom Protein Services for FIZ1
    GenScript Custom Purified and Recombinant Proteins Services for FIZ1
    Novus Biologicals FIZ1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for FIZ1

     
    Search eBioscience for Proteins for FIZ1 

     
    antibodies-online proteins for FIZ1 (2 products) 

     
    antibodies-online peptides for FIZ1

    FIZ1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for FIZ1
    Abcam antibodies for FIZ1
    Cloud-Clone Corp. Antibodies for FIZ1
    Search ThermoFisher Antibodies for FIZ1
    antibodies-online antibodies for FIZ1 (28 products) 

    FIZ1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for FIZ1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for FIZ1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for FIZ1
    Cloud-Clone Corp. CLIAs for FIZ1
    Search eBioscience for ELISAs for FIZ1 
    antibodies-online kits for FIZ1 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    ZNF: Zinc fingers, C2H2-type

    3 InterPro protein domains:
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q96SL8

    ProtoNet protein and cluster: Q96SL8

    UniProtKB/Swiss-Prot: FIZ1_HUMAN, Q96SL8
    Similarity: Contains 11 C2H2-type zinc fingers


    Find genes that share domains with FIZ1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FIZ1_HUMAN, Q96SL8
    Function: May be a transcriptional repressor of NRL function in photoreceptors. Does not repress CRX-mediated
    transactivation (By similarity)

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding IEA--
    GO:0005102receptor binding ISS--
    GO:0005515protein binding ----
    GO:0019901protein kinase binding ISS--
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with FIZ1           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for FIZ1:
     Decreased homologous recombina 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for FIZ1

    miRNA
    Products:
        
    miRTarBase miRNAs that target FIZ1:
    hsa-mir-484 (MIRT041828), hsa-mir-186-5p (MIRT021131), hsa-mir-335-5p (MIRT018416), hsa-mir-27a-3p (MIRT028700)

    Block miRNA regulation of human, mouse, rat FIZ1 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate FIZ1:
    hsa-miR-130b* hsa-miR-4255 hsa-miR-30b* hsa-miR-455-3p hsa-miR-3714
    SwitchGear 3'UTR luciferase reporter plasmidFIZ1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for FIZ1
    Predesigned siRNA for gene silencing in human, mouse, rat FIZ1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for FIZ1

    Clone
    Products:
         
    OriGene clones in human, mouse for FIZ1 (see all 9)
    OriGene ORF clones in mouse, rat for FIZ1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FIZ1 (NM_032836)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FIZ1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FIZ1

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for FIZ1
    Browse ESI BIO Cell Lines and PureStem Progenitors for FIZ1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FIZ1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    FIZ1_HUMAN, Q96SL8: Cytoplasm (By similarity). Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4
    golgi apparatus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS--
    GO:0005737cytoplasm ISS--

    Find genes that share ontologies with FIZ1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FIZ1
    Interactions:

        GeneGlobe Interaction Network for FIZ1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    4 Interacting proteins for FIZ1 (Q96SL83 ENSP000002216654) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FLT3P368883, ENSP000002414534I2D: score=2 STRING: ENSP00000241453
    MAP2K5Q131633I2D: score=2 
    NRLP548453I2D: score=2 
    --ENSP000003370234STRING: ENSP00000337023
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--

    Find genes that share ontologies with FIZ1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FIZ1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for FIZ1 gene: 
    NM_032836.2  

    Unigene Cluster for FIZ1:

    FLT3-interacting zinc finger 1
    Hs.515617  [show with all ESTs]
    Unigene Representative Sequence: NM_032836
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000221665(uc002qli.4 uc002qlj.4) ENST00000590714 ENST00000592585
    ENST00000587678 ENST00000587414
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat FIZ1 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate FIZ1:
    hsa-miR-130b* hsa-miR-4255 hsa-miR-30b* hsa-miR-455-3p hsa-miR-3714
    SwitchGear 3'UTR luciferase reporter plasmidFIZ1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for FIZ1
    Predesigned siRNA for gene silencing in human, mouse, rat FIZ1
    Clone
    Products:
         
    OriGene clones in human, mouse for FIZ1 (see all 9)
    OriGene ORF clones in mouse, rat for FIZ1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FIZ1 (NM_032836)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FIZ1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FIZ1
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for FIZ1
    OriGene qSTAR qPCR primer pairs in human, mouse for FIZ1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FIZ1
      QuantiTect SYBR Green Assays in human, mouse, rat FIZ1
      QuantiFast Probe-based Assays in human, mouse, rat FIZ1

    Additional mRNA sequence: 

    AK027674.1 BC020368.1 BC132777.1 BC136512.1 

    5 DOTS entries:

    DT.403910  DT.95254954  DT.86846015  DT.121445746  DT.100739580 

    Selected AceView cDNA sequences (see all 93):

    AW275332 AI990725 C01696 BU728526 BC020368 BM692120 BF594355 AW614655 
    AI096509 BM479809 BM663774 CA841110 BM690768 AW409891 F23452 BM974765 
    AW206984 CR596546 AI699699 AI143677 BG761413 AW768935 AA768320 AI830511 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    FIZ1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAATGGGCTG
    FIZ1 Expression
    About this image


    FIZ1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Bone (Muscoskeletal System)
             Mandibular Condyle
     
     Eye (Sensory Organs)
             Retina
    FIZ1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FIZ1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.515617

    UniProtKB/Swiss-Prot: FIZ1_HUMAN, Q96SL8
    Tissue specificity: Widely expressed

        Custom PCR Arrays for FIZ1
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for FIZ1
    OriGene qSTAR qPCR primer pairs in human, mouse for FIZ1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FIZ1
    QuantiTect SYBR Green Assays in human, mouse, rat FIZ1
    QuantiFast Probe-based Assays in human, mouse, rat FIZ1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FIZ1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for FIZ1 gene from Selected species (see all 6)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fiz11 , 5 Flt3 interacting zinc finger protein 11, 5 80.37(n)1
    87.08(a)1
      7 (2.90 cM)5
    238771  NM_011813.31  NP_035943.31 
     50070575 
    lizard
    (Anolis carolinensis)
    Reptilia FIZ16
    FLT3-interacting zinc finger 1
    48(a)
    1 ↔ 1
    GL343279.1(562763-581526)


    ENSEMBL Gene Tree for FIZ1 (if available)
    TreeFam Gene Tree for FIZ1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for FIZ1 gene
    Selected SIMAP similar genes for FIZ1 using alignment to 5 protein entries:     FIZ1_HUMAN (see all proteins) (see all similar genes):
    ZFP41    ZNF78L1    DKFZp434J0650    ZNF55    ZFS-4    ZNF696
    ZNF    ZNF516    HKR1    ZSCAN31    ZNF263    ZNF426
    HZF16    MYNN    ZNF283    ZNF420    ZNF253    DKFZp313M0722

    Find genes that share paralogs with FIZ1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for FIZ1 (see all 162)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs104033421,2
    C,F,H--52423311(+) TTCCTC/TATCCA 1 -- us2k118Minor allele frequency- T:0.14NS EA NA WA 2342
    rs1876748611,2
    --52423312(+) TCCTCA/GTCCAG 1 -- us2k10--------
    rs3104611,2
    C,A--52423364(-) GTTCCG/AGAGTG 1 -- us2k118Minor allele frequency- A:0.41NA PA EA WA CSA 852
    rs3104601,2
    C,A--52423391(-) CTGCTT/GACTGG 1 -- us2k114Minor allele frequency- G:0.19NA WA CSA EA 538
    rs1443511171,2
    --52423435(+) CTCTGG/TAGTTT 1 -- us2k10--------
    rs1483499321,2
    --52423447(+) ATGGGC/GTCTCC 1 -- us2k10--------
    rs2017115851,2
    C--52423521(+) TTTTTG/TTGGGG 1 -- us2k10--------
    rs1415974401,2
    --52423583(+) GAGAGA/TTAGGG 1 -- us2k10--------
    rs1509069031,2
    --52423671(+) ACCAGC/TATAGC 1 -- us2k10--------
    rs1477457621,2
    --56102281(+) TTTGAC/TTGATA 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for FIZ1 (56102737 - 56113336 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for FIZ1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv912499CNV Loss21882294
    nsv828643CNV Loss20364138
    nsv912502CNV Loss21882294
    dgv4025n71CNV Loss21882294
    nsv912473CNV Loss21882294
    nsv912500CNV Loss21882294
    nsv912501CNV Loss21882294
    nsv912486CNV Loss21882294
    dgv4026n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FIZ1
    DNA2.0 Custom Variant and Variant Library Synthesis for FIZ1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 609133    OMIM disorders: --


    Find genes that share disorders with FIZ1           About GenesLikeMe


    Export disorders for FIZ1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for FIZ1 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with FIZ1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Interaction of retinal bZIP transcription factor NRL with Flt3- interacting zinc-finger protein Fiz1: possible role of Fiz1 as a transcriptional repressor. (PubMed id 12566383)1, 2, 3, 9 Mitton K.P.... Swaroop A. (Hum. Mol. Genet. 2003)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Genome-wide association study of chronic periodontitis in a general German population. (PubMed id 24024966)1 Teumer A....Kocher T. (J. Clin. Periodontol. 2013)
    4. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    5. FIZ1 is expressed during photoreceptor maturation, and synergizes with NRL and CRX at rod-specific promoters in vitro. (PubMed id 17141759)1 Mali R.S....Mitton K.P. (Exp. Eye Res. 2007)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (Nature 2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. Fiz1, a novel zinc finger protein interacting with the receptor tyrosine kinase Flt3. (PubMed id 10409713)1 Wolf I. and Rohrschneider L.R. (J. Biol. Chem. 1999)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 84922 HGNC: 25917 AceView: FLJ14768 Ensembl:ENSG00000179943 euGenes: HUgn84922
    ECgene: FIZ1 H-InvDB: FIZ1

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for FIZ1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for FIZ1 gene:
    Search GeneIP for patents involving FIZ1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for FIZ1  
     OriGene qPCR primer pairs and template standards for FIZ1   OriGene Protein Over-expression Lysate for FIZ1  
     OriGene MassSpec for FIZ1   OriGene clones in human, mouse for FIZ1  
     OriGene qSTAR qPCR primer pairs in human, mouse for FIZ1   OriGene Purified Protein for FIZ1  
     OriGene ORF clones in mouse, rat for FIZ1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for FIZ1   OriGene Custom Protein Services for FIZ1  

     
     
     Block miRNA regulation of human, mouse, rat FIZ1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing FIZ1
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FIZ1 Predesigned siRNA for gene silencing in human, mouse, rat FIZ1
     QuantiFast Probe-based Assays in human, mouse, rat FIZ1 QuantiTect SYBR Green Assays in human, mouse, rat FIZ1
     Custom PCR Arrays for FIZ1 Search Chromatin IP Primers for FIZ1
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FIZ1  GeneGlobe Interaction Network for FIZ1
     Regulatory tfbs in FIZ1 promoter
     GenScript Custom Purified and Recombinant Proteins Services for FIZ1 GenScript cDNA clones with any tag delivered in your preferred vector for FIZ1
     GenScript Custom Assay Services for FIZ1 GenScript Custom overexpressing Cell Line Services for FIZ1
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for FIZ1
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     FIZ1 lysates
     Antibodies for FIZ1
     See all of Abcam's Antibodies, Kits and Proteins for FIZ1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for FIZ1
     Antibodies for FIZ1
     ELISAs for FIZ1
     CLIAs for FIZ1



     Browse ESI BIO Cell Lines and PureStem Progenitors for FIZ1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FIZ1
     SwitchGear 3'UTR luciferase reporter plasmids for FIZ1
     SwitchGear Promoter luciferase reporter plasmids for FIZ1
     Search ThermoFisher Antibodies for FIZ1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FIZ1
     Browse compounds at ApexBio
     Search Addgene for plasmids for FIZ1
      Search eBioscience for proteins for FIZ1
      Search eBioscience for elisas for FIZ1
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for FIZ1
     antibodies-online antibodies for FIZ1 (28 products)
     antibodies-online kits for FIZ1 (4 products)
     antibodies-online peptides for FIZ1
     antibodies-online proteins for FIZ1 (2 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      FIZ1 gene at Home site.
    Version: 3.12.248 16 Nov 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4