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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FIS1 Gene

protein-coding   GIFtS: 55
GCID: GC07M100882

Fission 1 (Mitochondrial Outer Membrane) Homolog (S. Cerevisiae)

(Previous names: tetratricopeptide repeat domain 11, fission 1 (mitochondrial...)
(Previous symbol: TTC11)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Fission 1 (Mitochondrial Outer Membrane) Homolog (S. Cerevisiae)1 2     TPR Repeat Protein 112 3
TTC111 2 3 5     CGI-135 Protein1
Tetratricopeptide Repeat Domain 111 2     Fission 1 (Mitochondrial Outer Membrane) Homolog (Yeast)1
Tetratricopeptide Repeat Protein 112 3     H_NH0132A01.62
FIS1 Homolog2 3     Mitochondrial Fission 1 Protein2
hFis12 3     

External Ids:    HGNC: 216891   Entrez Gene: 510242   Ensembl: ENSG000002142537   OMIM: 6090035   UniProtKB: Q9Y3D63   

Export aliases for FIS1 gene to outside databases

Previous GC identifers: GC07M100477 GC07M100665 GC07M095475


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FIS1 Gene:
The balance between fission and fusion regulates the morphology of mitochondria. TTC11 is a component of a
mitochondrial complex that promotes mitochondrial fission (James et al., 2003 (PubMed 12783892)).(supplied by
OMIM, Mar 2008)

GeneCards Summary for FIS1 Gene: 
FIS1 (fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)) is a protein-coding gene. Diseases associated with FIS1 include dental fluorosis, and spinocerebellar ataxia. GO annotations related to this gene include protein binding and receptor binding.

UniProtKB/Swiss-Prot: FIS1_HUMAN, Q9Y3D6
Function: Promotes the fragmentation of the mitochondrial network and its perinuclear clustering. Can induce
cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates
peroxisomal fission

Gene Wiki entry for FIS1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_007933.15  NC_018918.2  NT_079596.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FIS1 gene promoter:
         Max1   Egr-1   NRSF form 1   NRSF form 2   Arnt   YY1   FOXO1a   Pax-4a   c-Myc   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): FIS1 promoter sequence
   Search SABiosciences Chromatin IP Primers for FIS1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FIS1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q22.1   Ensembl cytogenetic band:  7q22.1   HGNC cytogenetic band: 7q22.1

FIS1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FIS1 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M100882:  view genomic region     (about GC identifiers)

Start:
100,882,739 bp from pter      End:
100,895,597 bp from pter
Size:
12,859 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 100,241,280-100,246,758     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: FIS1_HUMAN, Q9Y3D6 (See protein sequence)
Recommended Name: Mitochondrial fission 1 protein  
Size: 152 amino acids; 16938 Da
Subunit: Interacts with DNM1L/DLP1 through the TPR region. Interacts with MARCH5. Interacts with MID51
Subcellular location: Mitochondrion outer membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass
membrane protein
2 PDB 3D structures from and Proteopedia for FIS1:
1NZN (3D)        1PC2 (3D)    
Secondary accessions: Q9BTP3

Explore the universe of human proteins at neXtProt for FIS1: NX_Q9Y3D6

Explore proteomics data for FIS1 at MOPED 

Post-translational modifications:

  • UniProtKB: Ubiquitinated by MARCH5
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9Y3D6

  • FIS1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    FIS1 Protein Expression
    REFSEQ proteins: NP_057152.2  
    ENSEMBL proteins: 
     ENSP00000411442   ENSP00000442056   ENSP00000395964   ENSP00000223136   ENSP00000444771  
     ENSP00000413500  

    Human Recombinant Protein Products for FIS1: 
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    Browse Sino Biological Cell Lysates 
    ProSpec Recombinant Protein for FIS1
    Cloud-Clone Corp. Proteins for FIS1 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA--
    GO:0005777peroxisome ISS14561759
    GO:0005779integral to peroxisomal membrane IDA16107562
    GO:0031307integral to mitochondrial outer membrane NAS18845145
    GO:0043234protein complex IDA17408615

    FIS1 for ontologies           About GeneDecksing



    FIS1 Antibody Products: 
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    Assay Products for FIS1: 
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    Cloud-Clone Corp. CLIAs for FIS1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR016543 Tetratricopeptide_rpt_11_Fis1
     IPR011990 TPR-like_helical

    Graphical View of Domain Structure for InterPro Entry Q9Y3D6

    ProtoNet protein and cluster: Q9Y3D6

    UniProtKB/Swiss-Prot: FIS1_HUMAN, Q9Y3D6
    Domain: The C-terminus is required for mitochondrial or peroxisomal localization, while the N-terminus is
    necessary for mitochondrial or peroxisomal fission, localization and regulation of the interaction with DNM1L
    Similarity: Belongs to the FIS1 family
    Similarity: Contains 1 TPR repeat


    FIS1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FIS1_HUMAN, Q9Y3D6
    Function: Promotes the fragmentation of the mitochondrial network and its perinuclear clustering. Can induce
    cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates
    peroxisomal fission

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005102receptor binding IPI--
    GO:0005515protein binding IPI12861026
         
    FIS1 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for FIS1:
     G0/1 arrest  Increased G1 DNA content  Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for FIS1 
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    2 QIAGEN miScript miRNA Assays for microRNAs that regulate FIS1:
    hsa-miR-1266 hsa-miR-186*
    SwitchGear 3'UTR luciferase reporter plasmidFIS1 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for FIS1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 19)

    5/21 Interacting proteins for FIS1 (Q9Y3D61, 2, 3 ENSP000002231364) via UniProtKB, MINT, STRING, and/or I2D (see all 21)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BCAP31P515721, 2, 3, ENSP000003923304EBI-3385283,EBI-77683 MINT-8143489 MINT-8143644 MINT-8143627 MINT-8143480 MINT-8143498 MINT-8143661 MINT-8143690 MINT-8143706 I2D: score=1 STRING: ENSP00000392330
    DNM1LO004292, 3, ENSP000002664814MINT-8212925 I2D: score=2 STRING: ENSP00000266481
    MIEF1Q9NQG62, 3, ENSP000003271244MINT-8212968 MINT-8293136 MINT-8212925 MINT-8212955 I2D: score=1 STRING: ENSP00000327124
    UBCP0CG482, 3, ENSP000003448184MINT-2844122 I2D: score=2 STRING: ENSP00000344818
    MARCH5Q9NX472, 3, ENSP000003518134MINT-2844143 I2D: score=2 STRING: ENSP00000351813
    About this table

    Gene Ontology (GO): 5/18 biological process terms (GO ID links to tree view) (see all 18):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000266mitochondrial fission IMP19864424
    GO:0000422mitochondrion degradation IDA18515060
    GO:0001836release of cytochrome c from mitochondria IMP19864424
    GO:0006626protein targeting to mitochondrion IMP18845145
    GO:0007204elevation of cytosolic calcium ion concentration IMP--

    FIS1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    FIS1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FIS1

    1 Novoseek inferred chemical compound relationship for FIS1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    mdv 1 88 3 16272155 (2), 14623186 (1)

    Search CenterWatch for drugs/clinical trials and news about FIS1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for FIS1 gene: 
    NM_016068.2  

    Unigene Cluster for FIS1:

    Fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
    Hs.423968  [show with all ESTs]
    Unigene Representative Sequence: BM013783
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000449367 ENST00000482199 ENST00000474120(uc010lhu.3) ENST00000442303
    ENST00000463406 ENST00000223136(uc003uyj.4) ENST00000473527(uc010lht.3)
    ENST00000435848 ENST00000480497
    miRNA
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    2 QIAGEN miScript miRNA Assays for microRNAs that regulate FIS1:
    hsa-miR-1266 hsa-miR-186*
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    Inhib. RNA
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FIS1

    Additional mRNA sequence: 

    AF151893.1 AK310968.1 AK311665.1 BC003540.1 BC009428.1 

    9 DOTS entries:

    DT.91734186  DT.451632  DT.97843875  DT.100031408  DT.95200450  DT.91698157  DT.100676310  DT.446722 
    DT.120940423 

    24/325 AceView cDNA sequences (see all 325):

    BU857618 R49820 BI225269 AI129519 AI148099 AI961636 BI488904 AK056103 
    H95941 BM744462 BQ695317 AI299184 BU689241 BM781700 N93442 BM997988 
    BM764727 BC003540 BF725321 AI609056 AA142944 CA419123 AA181312 AI803601 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FIS1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGCTTTGGGA
    FIS1 Expression
    About this image


    See FIS1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FIS1

    SOURCE GeneReport for Unigene cluster: Hs.423968
        SABiosciences Expression via Pathway-Focused PCR Array including FIS1: 
              Mitochondria in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FIS1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for FIS1 gene from 7/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fis11 , 5 fission 1 (mitochondrial outer membrane) homolog (yeast)1, 5 89.04(n)1
    96.05(a)1
      5 (76.06 cM)5
    664371  NM_025562.31  NP_079838.11 
     1369532755 
    lizard
    (Anolis carolinensis)
    Reptilia FIS16
    Uncharacterized protein
    74(a)
    1 ↔ 1
    GL343220.1(4000-14430)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.106852 Transcribed sequence with moderate similarity to protein more 76.55(n)    BX689976.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BC054679.12   -- 67.63(n)    BC054679.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Fis11 CG17510-PA 53.15(n)
    49.32(a)
      49892  NM_001144135.1  NP_001137607.1 
    worm
    (Caenorhabditis elegans)
    Secernentea fis-21 Protein FIS-2 48.72(n)
    39.16(a)
      184409  NM_001029389.4  NP_001024560.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes FIS1(YIL065C)4 Protein involved in mitochondrial membrane fission more   --   9(241775-241308) 854745  NP_012199.1 


    ENSEMBL Gene Tree for FIS1 (if available)
    TreeFam Gene Tree for FIS1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FIS1 gene

    FIS1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for FIS1
    PGOHUM00000237328


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/120 SNPs in FIS1 are shown (see all 120)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1424618181,2
    C--100884186(+) AGCAGC/TTCTGG 2 E syn10--------
    rs1468327921,2
    C--100884210(+) AGAGGA/GTGAGA 1 -- int10--------
    rs1847727211,2
    --100884310(+) TCCTAA/CGCCTC 1 -- int10--------
    rs1868793051,2
    --100884502(+) GGCATC/TTGCTG 1 -- int10--------
    rs731859381,2
    C--100884535(+) TTTCAC/TTCGTC 1 -- int13Minor allele frequency- T:0.30NA EA 242
    rs1406761621,2
    C--100884684(+) TTCAGG/TAGAGA 1 -- int10--------
    rs132403131,2
    C--100884752(+) CTGCCT/CTGGCC 1 -- int11Minor allele frequency- C:0.00NA 2
    rs132275911,2
    C--100884753(+) TGCCCC/TGGCCT 1 -- int11Minor allele frequency- T:0.00NA 2
    rs1143170901,2
    --100884803(+) CTGTAC/TAATTA 1 -- int10--------
    rs1900126091,2
    C--100884888(+) TTCCCC/TGAAGA 1 -- int10--------

    HapMap Linkage Disequilibrium report for FIS1 (100882739 - 100895597 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for FIS1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2734888CNV Deletion23290073
    esv2422376CNV Duplication17116639
    esv2422326CNV Duplication17116639
    nsv5875CNV Insertion18451855
    nsv831075CNV Loss17160897
    nsv831076CNV Loss17160897
    nsv831077CNV Loss17160897
    dgv7410n71CNV Loss21882294
    esv2752134CNV Gain17911159

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609003    OMIM disorders: --

    8 diseases for FIS1:    About MalaCards
    dental fluorosis    spinocerebellar ataxia    crohn's disease    ataxia
    prostate cancer    prostatitis    alzheimer's disease    neuronitis

    1 disease from the University of Copenhagen DISEASES database for FIS1:
    Dental fluorosis

    FIS1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): FIS1
    Human Genome Epidemiology (HuGE) Navigator: FIS1 (1 document)

    Export disorders for FIS1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FIS1 gene, integrated from 9 sources (see all 59):
    (articles sorted by number of sources associating them with FIS1)
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    1. Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphology. (PubMed id 14996942)1, 2, 3 Stojanovski D.... Ryan M.T. (2004)
    2. The solution structure of human mitochondria fission protein Fis1 reveals a novel TPR-like helix bundle. (PubMed id 14623186)1, 2, 9 Suzuki M.... Tjandra N. (2003)
    3. Human MIEF1 recruits Drp1 to mitochondrial outer memb ranes and promotes mitochondrial fusion rather than fission. (PubMed id 21701560)1, 2 Zhao J....NistAcr M. (2011)
    4. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    5. A novel mitochondrial ubiquitin ligase plays a critical role in mitochondrial dynamics. (PubMed id 16874301)1, 2 Yonashiro R....Yanagi S. (2006)
    6. A role for Fis1 in both mitochondrial and peroxisomal fission in mammalian cells. (PubMed id 16107562)1, 2 Koch A.... Schrader M. (2005)
    7. Regulation of Ca2+-induced permeability transition by Bcl-2 is antagonized by Drpl and hFis1. (PubMed id 16010987)1, 3 Kong D....Kuo T.H. (2005)
    8. Regulation of mitochondrial fission and apoptosis by the mitochondrial outer membrane protein hFis1. (PubMed id 16118244)1, 2 Yu T.... Yoon Y. (2005)
    9. Cytosolic domain of the human mitochondrial fission protein fis1 adopts a TPR fold. (PubMed id 14705031)1, 2 Dohm J.A.... Gittis A.G. (2004)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51024 HGNC: 21689 AceView: CLDN15andTTC11 Ensembl:ENSG00000214253 euGenes: HUgn51024
    ECgene: FIS1 H-InvDB: FIS1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FIS1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for FIS1 gene:
    Search GeneIP for patents involving FIS1

    GeneCards and IP:
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