FIP1L1 Gene
protein-coding GIFtS: 53
GCID: GC04P054159
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|
FIP1 like 1 (S. cerevisiae)
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Aliases
for FIP1L1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| FIP1 Like 1 (S. Cerevisiae)1 2 | | Rhe2 | | Factor Interacting With PAP2 3 | | Pre-MRNA 3'-End-Processing Factor FIP12 | | Rearranged In Hypereosinophilia2 3 | | FIP13 | | FIP1-Like 1 Protein2 3 | | RHE3 | | HFip11 | | EC 1.1.1.868 | | DKFZp586K07171 | | EC 4.2.1.338 |
Export aliases for FIP1L1 gene to outside databasesPrevious GC identifers: GC04P054224 GC04P054093 GC04P054084 GC04P053938 GC04P050188 |
Summaries
for FIP1L1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for FIP1L1:
This gene encodes a subunit of the CPSF (cleavage and polyadenylation specificity factor) complex that polyadenylatesthe 3' end of mRNA precursors. This gene, the homolog of yeast Fip1 (factor interacting with PAP), binds to U-richsequences of pre-mRNA and stimulates poly(A) polymerase activity. Its N-terminus contains a PAP-binding site and itsC-terminus an RNA-binding domain. An interstitial chromosomal deletion on 4q12 creates an in-frame fusion of humangenes FIP1L1 and PDGFRA (platelet-derived growth factor receptor, alpha). The FIP1L1-PDGFRA fusion gene encodes aconstitutively activated tyrosine kinase that joins the first 233 amino acids of FIP1L1 to the last 523 amino acids ofPDGFRA. This gene fusion and chromosomal deletion is the cause of some forms of idiopathic hypereosinophilic syndrome(HES). This syndrome, recently reclassified as chronic eosinophilic leukemia (CEL), is responsive to treatment withtyrosine kinase inhibitors. Alternative splicing results in multiple transcript variants encoding distinct isoforms.(provided by RefSeq, Oct 2008)
UniProtKB/Swiss-Prot: FIP1_HUMAN, Q6UN15Function: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role inpre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and otherfactors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulatespoly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A)polymerase to the CPSF complex
Gene Wiki entry for FIP1L1
|
Genomic Views
for FIP1L1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_022853.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FIP1L1 gene promoter:
AML1a AP-1 MZF-1 AREB6 MEF-2A POU2F1 POU2F1a aMEF-2 TGIF ATF6
Other transcription factors
Search SABiosciences Chromatin IP Primers for FIP1L1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FIP1L1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q12 Ensembl cytogenetic band: 4q12 HGNC cytogenetic band: 4q11-q12FIP1L1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04P054159: view genomic region
(about GC identifiers)
Start:
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54,243,810 bp from pter |
End:
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55,161,439 bp from pter |
Size:
|
917,630 bases |
Orientation:
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plus strand |
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Proteins
for FIP1L1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: FIP1_HUMAN, Q6UN15 (See
protein sequence)Recommended Name: Pre-mRNA 3'-end-processing factor FIP1 Size: 594 amino acids; 66526 Da
Subunit: Component of the cleavage and polyadenylation specificity factor (CPSF) complex, composed of CPSF1, CPSF2,CPSF3, CPSF4 and FIP1L1. Found in a complex with CPSF1, FIP1L1 and PAPOLA. Interacts with CPSF1, CPSF4, CSTF2, CSTF3and PAPOLA
Subcellular location: Nucleus
Sequence caution: Sequence=AAH24016.1; Type=Miscellaneous discrepancy; Note=Intron retention; Sequence=AAH52959.1;Type=Miscellaneous discrepancy; Note=Intron retention;
Secondary accessions: B4DIR3 G3XAD6 Q0VGE0 Q499Y4 Q49AU3 Q7Z608 Q8WVN3 Q96F80 Q9H077Alternative splicing: 4 isoforms: Q6UN15-1 Q6UN15-3 Q6UN15-4 Q6UN15-5 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for FIP1L1: NX_Q6UN15
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6UN15
2 DME Specific Peptides for FIP1L1 (Q6UN15)
FIP1L1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001128409.1 NP_001128410.1 NP_112179.2
ENSEMBL proteins: ENSP00000336752 ENSP00000351383 ENSP00000425456 ENSP00000302993 ENSP00000423325 ENSP00000421241 ENSP00000421691
Human Recombinant Protein Products for FIP1L1:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IDA | -- | | GO:0005730 | NOT nucleolus |
IDA | -- | | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex |
IEA | -- |
FIP1L1 for ontologies About GeneDecksing
FIP1L1 Antibody Products:
Assay Products for FIP1L1: |
Protein
Domains /
Families
for FIP1L1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FIP1L1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q6UN15ProtoNet protein and cluster: Q6UN15 UniProtKB/Swiss-Prot: FIP1_HUMAN, Q6UN15Similarity: Belongs to the FIP1 family |
Function
for FIP1L1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: FIP1_HUMAN, Q6UN15Function: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role inpre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and otherfactors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulatespoly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A)polymerase to the CPSF complex Enzyme Numbers (IUBMB): EC 4.2.1.332 EC 1.1.1.862
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
FIP1L1 for ontologies About GeneDecksing
Phenotypes:
2 GenomeRNAi human phenotypes for FIP1L1:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FIP1L1 (see all 8)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FIP1L1 (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for FIP1L1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FIP1L1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FIP1L1 |
|
Pathways & Interactions
for FIP1L1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | mRNA surveillance pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Kegg Pathway (Kegg details for FIP1L1):
FIP1L1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for FIP1L1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 20)
5/568 Interacting proteins for FIP1L1 (Q6UN152, 3 ENSP000003367524) via UniProtKB, MINT, STRING, and/or I2D (see all 568)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006397 | mRNA processing |
IEA | -- |
FIP1L1 for ontologies About GeneDecksing
|
Drugs & Compounds
for FIP1L1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
FIP1L1 for compounds About GeneDecksing
 Browse Tocris compounds for FIP1L1
2 Novoseek chemical compound relationships for FIP1L1 gene About this table
Search CenterWatch for drugs/clinical trials and news about FIP1L1 / FIP1
|
Transcripts
for FIP1L1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FIP1L1 gene (3 alternative transcripts): NM_001134937.1 NM_001134938.1 NM_030917.3 Unigene Cluster for FIP1L1: FIP1 like 1 (S. cerevisiae) Hs.624245 [show with all ESTs]Unigene Representative Sequence: BC02401614 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000511376 ENST00000337488(uc003gzy.3) ENST00000358575(uc011bzu.2 uc003gzz.3)
ENST00000507922(uc003gzx.4) ENST00000306932 ENST00000505125(uc003hab.3)
ENST00000507166 ENST00000513975(uc011bzt.1) ENST00000510668 ENST00000514543
ENST00000513008 ENST00000504094(uc010ign.3 uc003hae.3) ENST00000511055
ENST00000507206
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FIP1L1 (see all 8)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FIP1L1 (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): FIP1L1 (NM_001134938) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FIP1L1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FIP1L1 |
Additional cDNA sequence: AF161429.1 AK090938.1 AK123992.1 AK295737.1 AK308145.1 AL136910.1 AY366510.1 BC011543.1 BC017724.1 BC024016.1 BC026724.1 BC052959.1 BC110383.1 23 DOTS entries: DT.100036591 DT.95225430 DT.100815951 DT.411959 DT.100808531 DT.95225468 DT.95225432 DT.97859095 DT.100776039 DT.121243782 DT.87016469 DT.100802830 DT.92450488 DT.100815950 DT.101984080 DT.121243770 DT.91690882 DT.100815949 DT.121243816 DT.100770792 DT.121243833 DT.75159342 DT.92450497 24/310 AceView cDNA sequences (see all 310): AI459296 AY366510 BE465031 BC026724 AA463253 BQ086238 Z43018 AI681701 BM725107 CR606214 BQ432281 CR595922 AW015930 BC062768 BM726946 BM015730 AI359589 CA432281 BQ229276 BX358104 AA150805 BF939534 CA420219 AA150702
GeneLoc Exon Structure
|
Expression
for FIP1L1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FIP1L1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See FIP1L1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FIP1L1
SOURCE GeneReport for Unigene cluster: Hs.624245
SABiosciences Custom PCR Arrays for FIP1L1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FIP1L1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FIP1L1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FIP1L1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FIP1L1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FIP1L1 |
Orthologs
for FIP1L1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for FIP1L1 gene from 9/27 species (see all 27) About this table
ENSEMBL Gene Tree for FIP1L1 (if available)
TreeFam Gene Tree for FIP1L1 (if available) |
Paralogs
for FIP1L1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FIP1L1 gene
- DROSHA2
FIP1L1 for paralogs About GeneDecksing
|
Genomic Variants
for FIP1L1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 4 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FIP1L1 (54243810 - 54493810 bp, first 250kb of FIP1L1)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FIP1L1: --
Human Gene Mutation Database (HGMD): FIP1L1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FIP1L1 |
|
Disorders
/ Diseases
for FIP1L1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
FIP1L1 for disorders About GeneDecksing
OMIM gene information: 607686
OMIM disorders: --
UniProtKB/Swiss-Prot: FIP1_HUMAN, Q6UN15
Note=A chromosomal aberration involving FIP1L1 is found in some cases of hypereosinophilic syndrome.Interstitial chromosomal deletion del(4)(q12q12) causes the fusion of FIP1L1 and PDGFRA (FIP1L1-PDGFRA)
16  diseases for FIP1L1: About MalaCardshypereosinophilic syndrome lfflers endocarditis mast-cell sarcoma leukemia
endomyocardial fibrosis polycythemia vera systemic mastocytosis mastocytosis
acute myeloid leukemia eosinophilia myeloid leukemia myelofibrosis
polycythemia endocarditis fibrosis sarcoma
7 diseases from the University of Copenhagen DISEASES database for FIP1L1:Eosinophilia Mastocytosis Endomyocardial fibrosis Leukemia
Myelofibrosis Polycythemia vera mast-cell sarcoma 3 Novoseek disease relationships for FIP1L1 gene About this table
Export disorders for FIP1L1 gene to outside databases
|
Publications
for FIP1L1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FIP1L1 gene, integrated from 9 sources (see all 64):
(articles sorted by number of sources associating them with FIP1L1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (2001)
- Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase. (PubMed id 14749727)1, 2, 9 Kaufmann I.... Keller W. (2004)
- A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome. (PubMed id 12660384)1, 2, 9 Cools J.... Gilliland D.G. (2003)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- A 57-nucleotide upstream early polyadenylation element in human papillomavirus type 16 interacts with hFip1, CstF-64, hnRNP C1/C2, and polypyrimidine tract binding protein. (PubMed id 15767428)1, 2 Zhao X.... Schwartz S. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Discovery of a fusion kinase in EOL-1 cells and idiopathic hypereosinophilic syndrome. (PubMed id 12808148)1, 2 Griffin J.H.... Briesewitz R. (2003)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
|
External Searches for FIP1L1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FIP1L1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FIP1L1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FIP1L1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for FIP1L1 gene:
Search GeneIP for patents involving FIP1L1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FIP1L1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FIP1L1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FIP1L1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FIP1L1 | | | OriGene Protein Over-expression Lysate for FIP1L1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FIP1L1 | | OriGene 3'-UTR Clone for FIP1L1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FIP1L1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FIP1L1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FIP1L1 | | OriGene Custom Protein Services for FIP1L1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FIP1L1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FIP1L1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FIP1L1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FIP1L1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FIP1L1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FIP1L1 |
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 | | | FIP1L1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FIP1L1 |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FIP1L1 |
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