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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FILIP1L Gene

protein-coding   GIFtS: 46
GCID: GC03M099548

filamin A interacting protein 1-like
 Explore 4 diseases affiliated with
FILIP1L via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for FILIP1L    

Aliases
for FILIP1L gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Filamin A Interacting Protein 1-Like1 2     GIP130a2
DOC-11 2 3     GIP130b2
GIP1301 2     GIP130c2
Protein Down-Regulated In Ovarian Cancer 12 3     Downregulated In Ovarian Cancer 1 81 KDa Isoform2
130 KDa GPBP-Interacting Protein2 3     Filamin A-Interacting Protein 1-Like2
90 KDa GPBP-Interacting Protein2 3     GPBP-Interacting Protein 902
DOC12 3     GPBP-Interacting Protein Of 130 KDa2
GIP902 3     COL4A3BPIP3

External Ids:    HGNC: 245891   Entrez Gene: 112592   Ensembl: ENSG000001683867   OMIM: 6129935   UniProtKB: Q4L1803   

Export aliases for FILIP1L gene to outside databases

Previous GC identifers: GC03M101035 GC03M096920


Summaries
for FILIP1L gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: FIL1L_HUMAN, Q4L180
Function: Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial
cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth
When expressed in tumor-associated vasculature




Genomic Views
for FILIP1L gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.1  NT_005612.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FILIP1L gene promoter:
         MEF-2   FOXO3   FOXO3b   MEF-2A   S8   FAC1   POU2F1   POU2F1a   FOXO3a   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 4): FILIP1L promoter sequence
   Search SABiosciences Chromatin IP Primers for FILIP1L

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FILIP1L


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q12.1   Ensembl cytogenetic band:  3q12.1   HGNC cytogenetic band: 3q12.1

FILIP1L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FILIP1L gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M099548:  view genomic region     (about GC identifiers)

Start:
 99,548,985 bp from pter      End:
 99,833,357 bp from pter
Size:
 284,373 bases      Orientation:
 minus strand

Proteins
for FILIP1L gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: FIL1L_HUMAN, Q4L180 (See protein sequence)
Recommended Name: Filamin A-interacting protein 1-like  
Size: 1135 amino acids; 130382 Da
Subcellular location: Cytoplasm. Membrane. Nucleus
Sequence caution: Sequence=AAA98972.1; Type=Frameshift; Positions=1000; Sequence=AAN16206.1; Type=Frameshift;
Positions=747; Sequence=ACB37436.1; Type=Frameshift; Positions=750;
Secondary accessions: B2CNV7 B2CNV8 Q13597 Q2YDY5 Q6KFX5 Q6KFX6 Q6KFX7 Q8IUM3 Q8N6Z0
Alternative splicing: 7 isoforms:  Q4L180-1   Q4L180-2   Q4L180-3   Q4L180-4   Q4L180-5   Q4L180-6   Q4L180-7   

Explore the universe of human proteins at neXtProt for FILIP1L: NX_Q4L180

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q4L180

    • FILIP1L Protein expression data from MOPED and PaxDb:    About this image 
    FILIP1L Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001035924.1  NP_055705.2  NP_878913.2  

    ENSEMBL proteins: 
     ENSP00000417617   ENSP00000346560   ENSP00000417774   ENSP00000419642   ENSP00000327880  
     ENSP00000419874   ENSP00000381371   ENSP00000373192  

    Human Recombinant Protein Products for FILIP1L: 
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    Uscn Proteins for FILIP1L

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--
    GO:0016020membrane IEA--
    GO:0016459myosin complex NAS--

    FILIP1L for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for FILIP1L

    Protein Domains /
    Families
    for FILIP1L gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    FILIP1L for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR019131 Cortactin-binding_p2_N

    Graphical View of Domain Structure for InterPro Entry Q4L180

    ProtoNet protein and cluster: Q4L180

    UniProtKB/Swiss-Prot: FIL1L_HUMAN, Q4L180
    Similarity: Belongs to the FILIP1 family


    Function
    for FILIP1L gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FIL1L_HUMAN, Q4L180
    Function: Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial
    cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth
    When expressed in tumor-associated vasculature
    Induction: Up-regulated in endothelial cells with the angiogenesis inhibitors endostatin and fumagillin. By endothelial
    monocyte-activating polypeptide II in endothelial cells

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    FILIP1L for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for FILIP1L 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FILIP1L
    8/19 QIAGEN miScript miRNA Assays for microRNAs that regulate FILIP1L (see all 19):
    hsa-miR-411* hsa-miR-3673 hsa-miR-379* hsa-miR-300 hsa-miR-519a hsa-miR-7-1* hsa-miR-1255a hsa-miR-205*
    SwitchGear 3'UTR luciferase reporter plasmid: FILIP1L 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FILIP1L (see all 4)
    OriGene shRNA RFP: FILIP1L
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    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of FILIP1L 
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    Clone
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    Cell Line
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    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FILIP1L


    Pathways & Interactions
    for FILIP1L gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FILIP1L

    2 Interacting proteins for FILIP1L (Q4L1803) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    APCP250543I2D: score=2 
    PLEKHA5Q9HAU03I2D: score=2 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    FILIP1L for ontologies           About GeneDecksing



    Drugs & Compounds
    for FILIP1L gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FILIP1L
    Search CenterWatch for drugs/clinical trials and news about FILIP1L / FIL1L 

    Transcripts
    for FILIP1L gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for FILIP1L gene (3 alternative transcripts): 
    NM_001042459.1  NM_014890.2  NM_182909.2  

    Unigene Cluster for FILIP1L:

    Filamin A interacting protein 1-like
    Hs.104672  [show with all ESTs]
    Unigene Representative Sequence: NM_001042459
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000476723 ENST00000477258 ENST00000354552(uc003dtm.3) ENST00000487087
    ENST00000471562 ENST00000331335(uc003dto.3) ENST00000495625 ENST00000398326
    ENST00000468533 ENST00000383694(uc010hpf.3 uc010hpg.3 uc003dtn.3 uc003dtp.1)


    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FILIP1L
    8/19 QIAGEN miScript miRNA Assays for microRNAs that regulate FILIP1L (see all 19):
    hsa-miR-411* hsa-miR-3673 hsa-miR-379* hsa-miR-300 hsa-miR-519a hsa-miR-7-1* hsa-miR-1255a hsa-miR-205*
    SwitchGear 3'UTR luciferase reporter plasmid: FILIP1L 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FILIP1L (see all 4)
    OriGene shRNA RFP: FILIP1L
    OriGene siRNA: FILIP1L
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FILIP1L
    Sirion Biotech Custom design and validation of potent shRNA sequences against FILIP1L 
    Clone
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    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FILIP1L (see all 4)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 3): FILIP1L (NM_001042459)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FILIP1L 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FILIP1L
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FILIP1L

    Additional cDNA sequence: 

    AF329092.1 AF514867.1 AF514868.1 AF514869.1 AK096195.1 AK225855.1 AY642382.1 BC017987.1 
    BC020941.1 BC027860.1 BC093085.1 EU531865.1 EU531866.1 L16887.1 U53445.1 

    16 DOTS entries:

    DT.100777694  DT.100025104  DT.100744951  DT.120914757  DT.455549  DT.75193441  DT.99929459  DT.101964078 
    DT.101964551  DT.95174716  DT.304633  DT.100777691  DT.120914917  DT.65286972  DT.120914822  DT.435762 

    24/173 AceView cDNA sequences (see all 173):

    F22190 NM_182909 BQ271726 AA258605 AW295168 AF514869 AW058260 CB242110 
    BF434332 AX776294 BQ086337 AF329092 AW026643 AI401231 AI635663 AI139164 
    CR613746 BQ272051 BG956208 AI783720 AL554096 CA392708 AI334138 BQ100981 

    GeneLoc Exon Structure


    Expression
    for FILIP1L gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FILIP1L expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AACTATACAA
    FILIP1L Expression
    About this image

    FILIP1L expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    Stem Cell Differentiation: 3 LifeMap Cells 
    NameCategory
    PureStem™ myogenic progenitor Z11 (Embryonic Progenitor Cell)Heart, Myocardium, Smooth Muscle
    PureStem™ progenitor EN2 (Embryonic Progenitor Cell)
    Pancreatic endoderm/endocrine precursor-like cells (A scalable, suspensi...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See FILIP1L Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FILIP1L

    SOURCE GeneReport for Unigene cluster: Hs.104672

    UniProtKB/Swiss-Prot: FIL1L_HUMAN, Q4L180
    Tissue specificity: Expressed in endothelial cells, colon and colon cancers. In the colon, expressed in the vasculature
    and muscularis mucosa. In colon cancer, strongly expressed in tumor stroma and the vasculature (at protein level).
    Expressed in ovarian epithelial cells. Down-regulated in ovarian cancer

        SABiosciences Custom PCR Arrays for FILIP1L
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    In Situ
    Assay Products:     
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    Orthologs
    for FILIP1L gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for FILIP1L gene from 6/17 species (see all 17)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Filip1l1 , 5 filamin A interacting protein 1-like1, 5 88.44(n)1
    88.76(a)1    		   16 (34.22 cM)5
    787491  NM_001040397.41  NP_001035487.21 
     573530935 
    chicken
    (Gallus gallus)    		 Aves FILIP1L1 filamin A interacting protein 1-like 73.45(n)
    74.33(a)    		   769163  XM_003640468.1  XP_003640516.1 
    lizard
    (Anolis carolinensis)    		 Reptilia FILIP1L6
    		 --
    		 70(a)
    		 1 ↔ 1
    		 3(174280189-174363907)
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc:1582921 zgc:158292 61.68(n)
    59.46(a)    		   100004879  NM_001110486.1  NP_001103956.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG109156
    		 --
    		 14(a)
    		 1 → many
    		 2R(14048225-14051714)
    worm
    (Caenorhabditis elegans)    		 Secernentea C49H3.66
    		 Protein C49H3.6, isoform a
    		 17(a)
    		 1 → many
    		 IV(7903726-7907071)


    ENSEMBL Gene Tree for FILIP1L (if available)
    TreeFam Gene Tree for FILIP1L (if available) 

    Paralogs
    for FILIP1L gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FILIP1L gene
    CTTNBP2NL2  CTTNBP22  FILIP12  LUZP12  
    3 SIMAP similar genes for FILIP1L using alignment to 3 protein entries:     FIL1L_HUMAN (see all proteins):
    FILIP1    LUZP1    CTTNBP2NL

    FILIP1L for paralogs           About GeneDecksing



    Genomic Variants
    for FILIP1L gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/4164 NCBI SNPs in FILIP1L are shown (see all 4164)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 3 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1121013481,2
    		C--99551577(+) TACTTG/-GGAGG 2 -- ds5001 int11Minor allele frequency- -:0.00CSA 2
    rs50193131,2
    		A--99551705(+) AAGTTG/TTTTTT 2 -- int1 ds50010--------
    rs675054181,2
    		C--99551705(+) AAGTT-/GTTTTT 2 -- ds5001 int10--------
    rs1487716301,2
    		--99551754(+) AGTAAA/TTGAGG 2 -- int1 ds50010--------
    rs287281761,2
    		C--99551839(+) TGTCCA/GAATTT 2 -- int1 ds50010--------
    rs1508621881,2
    		--99552025(+) CCCAGC/TTCAAC 2 -- ut31 int10--------
    rs2013379021,2
    		F--99552049(+) TTTGGA/GATGCC 2 -- int1 ut311Minor allele frequency- G:0.00EU 1323
    rs1903092201,2
    		C--99552147(+) GAATAA/TATTAA 2 -- int10--------
    rs1148705501,2
    		F--99552536(+) GGAGCG/AGTCCT 2 -- int11Minor allele frequency- A:0.02WA 118
    rs1155524761,2
    		F--99552645(+) TGGGAC/TGGTGG 2 -- int12Minor allele frequency- T:0.01WA NA 238

    HapMap Linkage Disequilibrium report for FILIP1L (99548985 - 99798985 bp, first 250kb of FILIP1L)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 8 variations for FILIP1L
         8 Indels: 43201 98390 63533 42739 79845 91445 40544 40545

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FILIP1L
    DNA2.0 Custom Variant and Variant Library Synthesis for FILIP1L

    Disorders / Diseases
    for FILIP1L gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    FILIP1L for disorders           About GeneDecksing

    OMIM gene information: 612993    OMIM disorders: --

    4 diseases for FILIP1L:    About MalaCards
    ovarian cancer    epithelial ovarian cancer    colon cancer    melanoma

    Human Genome Epidemiology (HuGE) Navigator: FILIP1L (3 documents)

    Export disorders for FILIP1L gene to outside databases

    Publications
    for FILIP1L gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FILIP1L gene, integrated from 9 sources (see all 17):
    (articles sorted by number of sources associating them with FILIP1L)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Endothelial monocyte activating polypeptide-II induced gene expression changes in endothelial cells. (PubMed id 15935955)1, 2, 3, 9 Tandle A.T.... Libutti S.K. (2005)
    2. Molecular cloning of differentially expressed genes in human epithelial ovarian cancer. (PubMed id 8314147)1, 2, 3 Mok S.C....Berkowitz R.S. (1994)
    3. Goodpasture antigen-binding protein (GPBP) directs my ofibril formation: identification of intracellular downstream effector 130-kDa GPBP-interacting protein (GIP130). (PubMed id 21832087)1, 3 Revert-Ros F....Saus J. (2011)
    4. Genome-wide meta-analyses of nonsyndromic cleft lip wi th or without cleft palate identify six new risk loci. (PubMed id 22863734)1 Ludwig K.U....Nothen M.M. (2012)
    5. Downregulation of Filamin A interacting protein 1-lik e is associated with promoter methylation and induces an invasive phenotype in ovarian cancer. (PubMed id 21693594)1 Burton E.R....Kwon M. (2011)
    6. Promotion of heat shock factor Hsf1 degradation via a daptor protein filamin A-interacting protein 1-like (FILIP-1L). (PubMed id 21784850)1 Hu Y. and Mivechi N.F. (2011)
    7. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    8. Common alleles in candidate susceptibility genes asso ciated with risk and development of epithelial ovarian cancer. (PubMed id 20635389)1 Notaridou M.... . (2010)
    9. Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival. (PubMed id 19270026)1 Quaye L....Gayther S.A. (2009)
    10. Functional characterization of filamin a interacting protein 1-like, a novel candidate for antivascular cancer therapy. (PubMed id 18794120)2 Kwon M.... Libutti S.K. (2008)

    External Searches for FILIP1L gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
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    Genome Databases showing FILIP1L gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 11259 HGNC: 24589 AceView: DOC1 Ensembl:ENSG00000168386 euGenes: HUgn11259
    ECgene: FILIP1L H-InvDB: FILIP1L

    Other Databases showing FILIP1L gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing FILIP1L gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FILIP1L Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for FILIP1L gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for FILIP1L gene:
    Search GeneIP for patents involving FILIP1L

    GeneCards and IP:
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