Aliases for FILIP1 Gene
External Ids for FILIP1 Gene
Previous GeneCards Identifiers for FILIP1 Gene
This gene encodes a filamin A binding protein. The encoded protein promotes the degradation of filamin A and may regulate cortical neuron migration and dendritic spine morphology. Mice lacking a functional copy of this gene exhibit reduced dendritic spine length and altered excitatory signaling. [provided by RefSeq, Oct 2016]
GeneCards Summary for FILIP1 Gene
FILIP1 (Filamin A Interacting Protein 1) is a Protein Coding gene. Diseases associated with FILIP1 include Ureterocele. Among its related pathways are Integrated Breast Cancer Pathway. An important paralog of this gene is FILIP1L.
UniProtKB/Swiss-Prot for FILIP1 Gene
By acting through a filamin-A/F-actin axis, it controls the start of neocortical cell migration from the ventricular zone. May be able to induce the degradation of filamin-A.