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Aliases for FIGNL2 Gene

Aliases for FIGNL2 Gene

  • Fidgetin-Like 2 2 3

External Ids for FIGNL2 Gene

Summaries for FIGNL2 Gene

GeneCards Summary for FIGNL2 Gene

FIGNL2 (Fidgetin-Like 2) is a Protein Coding gene. GO annotations related to this gene include nucleoside-triphosphatase activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FIGNL2 Gene

Genomics for FIGNL2 Gene

Genomic Location for FIGNL2 Gene

Start:
51,817,892 bp from pter
End:
51,848,580 bp from pter
Size:
30,689 bases
Orientation:
Minus strand

Genomic View for FIGNL2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FIGNL2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FIGNL2 Gene

Regulatory Elements for FIGNL2 Gene

Proteins for FIGNL2 Gene

  • Protein details for FIGNL2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NMB9-FIGL2_HUMAN
    Recommended name:
    Putative fidgetin-like protein 2
    Protein Accession:
    A6NMB9
    Secondary Accessions:

    Protein attributes for FIGNL2 Gene

    Size:
    653 amino acids
    Molecular mass:
    66603 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FIGNL2 Gene

Proteomics data for FIGNL2 Gene at MOPED

Post-translational modifications for FIGNL2 Gene

No Post-translational modifications

Other Protein References for FIGNL2 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for FIGNL2 Gene

Domains for FIGNL2 Gene

Gene Families for FIGNL2 Gene

HGNC:
  • AATP :ATPases / AAA-type

Protein Domains for FIGNL2 Gene

UniProtKB/Swiss-Prot:

FIGL2_HUMAN
Family:
  • Belongs to the AAA ATPase family.:
    • A6NMB9
genes like me logo Genes that share domains with FIGNL2: view

Function for FIGNL2 Gene

Gene Ontology (GO) - Molecular Function for FIGNL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005524 ATP binding IEA --
genes like me logo Genes that share ontologies with FIGNL2: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FIGNL2 Gene

Localization for FIGNL2 Gene

No data available for Gene Ontology (GO) - Cellular Components for FIGNL2 Gene

Pathways for FIGNL2 Gene

SuperPathways for FIGNL2 Gene

No Data Available

Interacting Proteins for FIGNL2 Gene

Gene Ontology (GO) - Biological Process for FIGNL2 Gene

None

No data available for Pathways by source for FIGNL2 Gene

Transcripts for FIGNL2 Gene

mRNA/cDNA for FIGNL2 Gene

(4) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FIGNL2 Gene

Fidgetin-like 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FIGNL2 Gene

No ASD Table

Relevant External Links for FIGNL2 Gene

GeneLoc Exon Structure for
FIGNL2
ECgene alternative splicing isoforms for
FIGNL2

Expression for FIGNL2 Gene

mRNA expression in normal human tissues for FIGNL2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

SOURCE GeneReport for Unigene cluster for FIGNL2 Gene Hs.648218

genes like me logo Genes that share expressions with FIGNL2: view

Orthologs for FIGNL2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for FIGNL2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FIGNL2 36
  • 96.45 (n)
  • 95.26 (a)
cow
(Bos Taurus)
Mammalia FIGNL2 36
  • 88.62 (n)
  • 92.31 (a)
mouse
(Mus musculus)
Mammalia Fignl2 36
  • 83.93 (n)
  • 85.54 (a)
Fignl2 16
rat
(Rattus norvegicus)
Mammalia Fignl2 36
  • 85.66 (n)
  • 88.69 (a)
Species with no ortholog for FIGNL2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FIGNL2 Gene

ENSEMBL:
Gene Tree for FIGNL2 (if available)
TreeFam:
Gene Tree for FIGNL2 (if available)

Paralogs for FIGNL2 Gene

Selected SIMAP similar genes for FIGNL2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FIGNL2: view

No data available for Paralogs for FIGNL2 Gene

Variants for FIGNL2 Gene

Sequence variations from dbSNP and Humsavar for FIGNL2 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs186231 -- 51,818,705(+) CTGAG(A/G)TGGGA utr-variant-3-prime
rs303780 -- 51,848,477(-) TGTCC(A/G)GAGCT intron-variant
rs303781 -- 51,848,339(-) ACTTC(C/T)CGGGG intron-variant
rs303782 -- 51,847,922(-) GTCAG(A/G)GGGTT intron-variant
rs303783 -- 51,845,970(-) TTATT(C/T)GCCTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FIGNL2 Gene

Variant ID Type Subtype PubMed ID
nsv826373 CNV Gain 20364138
esv2659984 CNV Deletion 23128226
nsv826374 CNV Gain 20364138
esv28148 CNV Loss 19812545

Relevant External Links for FIGNL2 Gene

HapMap Linkage Disequilibrium report
FIGNL2

Disorders for FIGNL2 Gene

Relevant External Links for FIGNL2

Genetic Association Database (GAD)
FIGNL2
genes like me logo Genes that share disorders with FIGNL2: view

No data available for UniProtKB/Swiss-Prot for FIGNL2 Gene

Publications for FIGNL2 Gene

  1. The mouse fidgetin gene defines a new role for AAA family proteins in mammalian development. (PMID: 11017077) Cox G.A. … Frankel W.N. (Nat. Genet. 2000) 2 3
  2. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer S.E. … Gibbs R.A. (Nature 2006) 3 4
  3. Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia. (PMID: 21107309) McClay J.L. … van den Oord E.J. (Neuropsychopharmacology 2011) 49
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3

Products for FIGNL2 Gene

Sources for FIGNL2 Gene

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