Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

FIBCD1 Gene

protein-coding GIFtS: 47
GCID: GC09M133777

fibrinogen C domain containing 1

Explore 2 diseases affiliated with
FIBCD1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Fibrinogen C Domain Containing 1¹ ²
FLJ14810¹
Fibrinogen C Domain-Containing Protein 1²

External Ids:	HGNC: 25922¹	Entrez Gene: 84929²	Ensembl: ENSG00000130720⁷	OMIM: 613357⁵	UniProtKB: Q8N539³

Export aliases for FIBCD1 gene to outside databases

Previous GC identifers: GC09M129053 GC09M130807 GC09M132767 GC09M103264

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FIBCD1:

FIBCD1 is a conserved type II transmembrane endocytic receptor that binds chitin and is located primarily in the

intestinal brush border (Schlosser et al., 2009 (PubMed 19710473)).(supplied by OMIM, Apr 2010)

UniProtKB/Swiss-Prot: FBCD1_HUMAN, Q8N539

Function: Acetyl group-binding receptor which shows a high-affinity and calcium-dependent binding to acetylated

structures such as chitin, some N-acetylated carbohydrates, and amino acids, but not to their non-acetylated

counterparts. Can facilitate the endocytosis of acetylated components

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000009.11 NC_018920.1 NT_035014.4

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the FIBCD1 gene promoter:
E2F-4 E2F-3a E2F-1 E2F E2F-2 Egr-4
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: FIBCD1 promoter sequence

Search SABiosciences Chromatin IP Primers for FIBCD1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FIBCD1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.12 Ensembl cytogenetic band: 9q34.12 HGNC cytogenetic band: 9q34.2

FIBCD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FIBCD1 gene location

GeneLoc information about chromosome 9 GeneLoc Exon Structure

GeneLoc location for GC09M133777: view genomic region (about GC identifiers)

Start:	133,777,825 bp from pter	End:	133,814,673 bp from pter
Size:	36,849 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: FBCD1_HUMAN, Q8N539 (See protein sequence)

Recommended Name: Fibrinogen C domain-containing protein 1

Size: 461 amino acids; 50744 Da

Subunit: Homotetramer; disulfide-linked

Subcellular location: Membrane; Single-pass type II membrane protein (Potential)

Secondary accessions: A3KFK0 Q6UXK6 Q96SJ7

Alternative splicing: 2 isoforms: Q8N539-1 Q8N539-2

Explore the universe of human proteins at neXtProt for FIBCD1: NX_Q8N539

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8N539

FIBCD1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001138578.1 NP_116232.3

ENSEMBL proteins:

ENSP00000361413 ENSP00000361412 ENSP00000395319 ENSP00000393894 ENSP00000253018

ENSP00000414501

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate: FIBCD1 OriGene Custom Protein Services for FIBCD1
	GenScript Custom Purified and Recombinant Proteins Services for FIBCD1
	Novus Biologicals FIBCD1 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for FIBCD1

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005615	extracellular space	IEA	--
GO:0016020	membrane	IDA	19710473
GO:0016021	integral to membrane	IEA	--

FIBCD1 for ontologies About GeneDecksing

FIBCD1 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for FIBCD1
	GenScript Custom Superior Antibodies Services for FIBCD1
	Novus Biologicals FIBCD1 Antibody
	Search for Antibodies for FIBCD1 at Abcam
	Uscn Antibodies for FIBCD1
	ThermoFisher Antibodies for FIBCD1

Assay Products for FIBCD1:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for FIBCD1
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for FIBCD1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

FIBCD1 for domains About GeneDecksing

4 InterPro domains/families:

IPR014715 Fibrinogen_a/b/g_C_2

IPR014716 Fibrinogen_a/b/g_C_1

IPR020837 Fibrinogen_CS

IPR002181 Fibrinogen_a/b/g_C_dom

Graphical View of Domain Structure for InterPro Entry Q8N539

ProtoNet protein and cluster: Q8N539

1 Blocks protein family: IPB002181 Fibrinogen

UniProtKB/Swiss-Prot: FBCD1_HUMAN, Q8N539

Similarity: Contains 1 fibrinogen C-terminal domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: FBCD1_HUMAN, Q8N539

Function: Acetyl group-binding receptor which shows a high-affinity and calcium-dependent binding to acetylated

structures such as chitin, some N-acetylated carbohydrates, and amino acids, but not to their non-acetylated

counterparts. Can facilitate the endocytosis of acetylated components

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FIBCD1
		3 QIAGEN miScript miRNA Assays for microRNAs that regulate FIBCD1:
		hsa-miR-4291 hsa-miR-922 hsa-miR-324-3p
		SwitchGear 3'UTR luciferase reporter plasmid: FIBCD1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FIBCD1 (see all 7) OriGene shRNA RFP: FIBCD1 OriGene siRNA: FIBCD1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FIBCD1

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for FIBCD1

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FIBCD1 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FIBCD1 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): FIBCD1 (NM_032843)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for FIBCD1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FIBCD1

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for FIBCD1
		Search LifeMap BioReagents cell lines for FIBCD1

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FIBCD1

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005102	receptor binding	IEA	--
GO:0008061	chitin binding	IDA	19710473
GO:0046872	metal ion binding	IEA	--

FIBCD1 for ontologies About GeneDecksing

2 GenomeRNAi human phenotypes for FIBCD1:

Increased cell number in G2M,

Increased gamma-H2AX phosphory

Animal Models:
Mouse knock-out Fibcd1^tm1Lex for FIBCD1
1 MGI phenotypic allele

for Fibcd1 (no phenotypes)

FIBCD1 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for FIBCD1

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007165	signal transduction	IEA	--

FIBCD1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for FIBCD1
Search CenterWatch for drugs/clinical trials and news about FIBCD1 / FBCD1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for FIBCD1 gene (2 alternative transcripts):

NM_001145106.1 NM_032843.4

Unigene Cluster for FIBCD1:

Fibrinogen C domain containing 1

Hs.133205 [show with all ESTs]

Unigene Representative Sequence: NM_032843

8 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000372338(uc004bzz.3) ENST00000372337 ENST00000444139 ENST00000451466(uc011mcd.1)

ENST00000463475 ENST00000486250 ENST00000253018 ENST00000448616(uc011mcc.2)

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FIBCD1
		3 QIAGEN miScript miRNA Assays for microRNAs that regulate FIBCD1:
		hsa-miR-4291 hsa-miR-922 hsa-miR-324-3p
		SwitchGear 3'UTR luciferase reporter plasmid: FIBCD1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FIBCD1 (see all 7) OriGene shRNA RFP: FIBCD1 OriGene siRNA: FIBCD1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FIBCD1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FIBCD1 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FIBCD1 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): FIBCD1 (NM_032843)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for FIBCD1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FIBCD1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FIBCD1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat FIBCD1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FIBCD1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FIBCD1

Additional cDNA sequence:

AK027716.1 AK292489.1 AK300287.1 AY358311.1 BC032953.2 BC112892.1

4 DOTS entries:

DT.100741345 DT.97836274 DT.99977080 DT.121204191

24/36 AceView cDNA sequences (see all 36):

BM717651 BF792773 AW444468 NM_032843 BX344639 BM678238 BM725227 BX400744

AY358311 BX400745 BX283252 BX344638 AI004635 BG419931 BQ184686 BG699199

BC032953 AI218434 AK027716 BF793377 AI611649 AI742071 AL578444 BM544458

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for FIBCD1 About this scheme

ExUns:	1	^	2	^	3a	·	3b	^	4	^	5a	·	5b	^	6	^	7	^	8	^	9	^	10a	·	10b	·	10c
SP1:									-
SP2:																					-		-
SP3:					-				-
SP4:			-		-

ECgene alternative splicing isoforms for FIBCD1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

FIBCD1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

FIBCD1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

10 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Spinal Cord

Spinal Dorsal Columns

Dorsal Spinal Cord Progenitor Cells

Spinal Cord

Spinal Ventral Columns

Ventral Spinal Cord Progenitor Cells

Motor Neurons

Brain

Brain

Diencephalic Ventricular Zone

Neural Tube

Mesencephalic Ventricular Zone

Neural Tube

Metencephalon

Neural Tube

Telencephalon

Neural Tube

Spinal Cord

Spinal Dorsal Columns

Spinal Cord

Spinal Ventral Columns

Spinal Cord

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

PureStem™ progenitor E68 (Embryonic Progenitor Cell)

PureStem™ progenitor RASMO12 (Embryonic Progenitor Cell)

See FIBCD1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FIBCD1

SOURCE GeneReport for Unigene cluster: Hs.133205

UniProtKB/Swiss-Prot: FBCD1_HUMAN, Q8N539

Tissue specificity: Expressed in the small and large intestinal epithelial cells with a highly polarized localization

to the apical surface corresponding to the brush border and in the ducts of the salivary gland

SABiosciences Custom PCR Arrays for FIBCD1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FIBCD1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat FIBCD1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FIBCD1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FIBCD1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FIBCD1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for FIBCD1 gene from 5/15 species (see all 15) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	FIBCD1¹	fibrinogen C domain containing 1	75.6(n) 73.42(a)		427762 XM_425335.3 XP_425335.2
lizard (Anolis carolinensis)	Reptilia	FIBCD1⁶	--	85(a)	1 ↔ 1	AAWZ02037078(4652-8526)
African clawed frog (Xenopus laevis)	Amphibia	Xl.6455²	Xenopus laevis transcribed sequences	71.83(n)		CA790169.1
zebrafish (Danio rerio)	Actinopterygii	si:dkeyp-51b7.3¹	si:dkeyp-51b7.3	69.21(n) 67.54(a)		100151577 XM_001922310.2 XP_001922345.2
fruit fly (Drosophila melanogaster)	Insecta	CG10359⁶	--	16(a)	1 ↔ 1	3L(3612192-3615244)

ENSEMBL Gene Tree for FIBCD1 (if available)
TreeFam Gene Tree for FIBCD1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for FIBCD1 gene

TNR² FCN3² FCN1² FCN2² TNXB² TNN² MFAP4² FN1²

TNC² ANGPTL5²

18/20 SIMAP similar genes for FIBCD1 using alignment to 5 protein entries: FBCD1_HUMAN (see all proteins) (see all similar genes):

ANGPT2 MFAP4 FCN2 TNR TNC FCN3

TNC variant protein FGL1 ANGPTL2 LFIRE1 TNXB FCN1

ANGPT1 ANGPTL1 ANGPTL7 FGG ANGPTL4 AngA

FIBCD1 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for FIBCD1
PGOHUM00000250514

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 9 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs4063946^1,2	C,	--	133777390(-)	`CAAACAAAC/- TCCTG`	2	--	ds500¹		1		NA	2
rs115379420^1,2	F,	--	133777498(+)	`GGGGGG/ACTCCT`	2	--	ds500¹		1		WA	118
rs66744285^1,2	C,F,	--	133777588(+)	`CTTGGC/ATTCTA`	2	--	ds500¹		5		NA WA CSA	244
rs10217294^1,2	C,F,A,H,	--	133777628(+)	`TTCCCG/TTTGAA`	2	--	ds500¹		23		NS EA NA WA CSA	2738
rs115258335^1,2	F,	--	133777694(+)	`CTCCAG/TCCACC`	2	--	ds500¹		1		WA	118
rs138111679^1,2		--	133777748(+)	`TCTGCA/GTCCAG`	2	--	ds500¹		0	--	--	--	--
rs45590433^1,2	C,	--	133777761(+)	`GAGGAC/TCGAGA`	2	--	ds500¹		2		NA	122
rs149451082^1,2		--	133777816(+)	`AAGCGC/TTGCAG`	2	--	ds500¹		0	--	--	--	--
rs59375843^1,2	C,	--	133777862(+)	`ACAGAG/AAGCCA`	2	--	ut3¹		3		WA NA	240
rs11789517^1,2	C,F,H,	--	133777993(+)	`ATCGGG/TTGTCC`	2	--	ut3¹ ese³		12		NS EA NA	1766

HapMap Linkage Disequilibrium report for FIBCD1 (133777825 - 133814673 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for FIBCD1
2 CNVs: 3782 31530

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FIBCD1

DNA2.0 Custom Variant and Variant Library Synthesis for FIBCD1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

FIBCD1 for disorders           About GeneDecksing

OMIM gene information: 613357    OMIM disorders: --

2 diseases for FIBCD1:    About MalaCards

hepatitis b hepatitis

Human Genome Epidemiology (HuGE) Navigator: FIBCD1 (1 document)

Export disorders for FIBCD1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for FIBCD1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with FIBCD1)

Utopia: connect your pdf to the dynamic
world of online information

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2, 3} Clark H.F.... Gray A.M. (2003)
The recognition unit of FIBCD1 organizes into a noncovalently linked tetrameric structure and uses a hydrophobic funnel (S1) for acetyl group recognition. (PubMed id 19892701)^{1, 2} Thomsen T.... Holmskov U. (2010)
Characterization of FIBCD1 as an acetyl group-binding receptor that binds chitin. (PubMed id 19710473)^{1, 2} Schlosser A.... Holmskov U. (2009)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)¹ Davila S....Seielstad M. (2010)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)² Humphray S.J.... Dunham I. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 84929	HGNC: 25922	AceView: FIBCD1	Ensembl:ENSG00000130720	euGenes: HUgn84929
ECgene: FIBCD1	H-InvDB: FIBCD1

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for FIBCD1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for FIBCD1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for FIBCD1 gene:
Search GeneIP for patents involving FIBCD1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for FIBCD1
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FIBCD1		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FIBCD1
	OriGene Protein Over-expression Lysate for FIBCD1		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for FIBCD1		Browse 3'-UTR reporter clones for miRNA target validation
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FIBCD1		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FIBCD1
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for FIBCD1		OriGene Custom Protein Services for FIBCD1
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FIBCD1
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FIBCD1
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FIBCD1
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FIBCD1
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FIBCD1
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FIBCD1

	GenScript Custom Purified and Recombinant Proteins Services for FIBCD1		GenScript cDNA clones with any tag delivered in your preferred vector for FIBCD1
	GenScript Custom Assay Services for FIBCD1		GenScript Custom Superior Antibodies Services for FIBCD1
	GenScript Custom overexpressing Cell Line Services for FIBCD1		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in FIBCD1 promoter
	Search Chromatin IP Primers for FIBCD1
	RT² qPCR Primer Assay in human, mouse, rat FIBCD1
	Search GNC Networks for FIBCD1
	SABiosciences Custom PCR Arrays for FIBCD1

Search Tocris compounds for FIBCD1

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	FIBCD1 antibodies
	FIBCD1 lysates

	Search for Antibodies for FIBCD1 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for FIBCD1
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

FIBCD1 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for FIBCD1

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FIBCD1

	SwitchGear 3'UTR luciferase reporter plasmids for FIBCD1
	SwitchGear Promoter luciferase reporter plasmids for FIBCD1

ThermoFisher Antibodies for FIBCD1

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FIBCD1

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes FIBCD1 gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4

Advanced Search

Export list of displayed genes

FIBCD1 Gene

fibrinogen C domain containing 1

Aliases
for FIBCD1 gene

Summaries
for FIBCD1 gene

Genomic Views
for FIBCD1 gene

Proteins
for FIBCD1 gene

Protein Domains /
Families
for FIBCD1 gene

Function
for FIBCD1 gene

Pathways & Interactions
for FIBCD1 gene

Drugs & Compounds
for FIBCD1 gene

Transcripts
for FIBCD1 gene

Expression
for FIBCD1 gene

Orthologs
for FIBCD1 gene

Paralogs
for FIBCD1 gene

Genomic Variants
for FIBCD1 gene

Disorders / Diseases
for FIBCD1 gene

Publications
for FIBCD1 gene

External Searches for FIBCD1 gene

Genome Databases showing FIBCD1 gene

Other Databases showing FIBCD1 gene

Specialized Databases showing FIBCD1 gene

Intellectual Property
for FIBCD1 gene

Products
for FIBCD1 gene

View Random Gene

Advanced Search

Export list of displayed genes

FIBCD1 Gene

fibrinogen C domain containing 1

Aliasesfor FIBCD1 gene

Summariesfor FIBCD1 gene

Genomic Viewsfor FIBCD1 gene

Proteinsfor FIBCD1 gene

Protein Domains /Familiesfor FIBCD1 gene

Functionfor FIBCD1 gene

Pathways & Interactionsfor FIBCD1 gene

Drugs & Compoundsfor FIBCD1 gene

Transcriptsfor FIBCD1 gene

Expression for FIBCD1 gene

Orthologsfor FIBCD1 gene

Paralogsfor FIBCD1 gene

Genomic Variantsfor FIBCD1 gene

Disorders / Diseasesfor FIBCD1 gene

Publicationsfor FIBCD1 gene

External Searches for FIBCD1 gene

Genome Databases showing FIBCD1 gene

Other Databases showing FIBCD1 gene

Specialized Databases showing FIBCD1 gene

Intellectual Propertyfor FIBCD1 gene

Productsfor FIBCD1 gene

View Random Gene

Aliases
for FIBCD1 gene

Summaries
for FIBCD1 gene

Genomic Views
for FIBCD1 gene

Proteins
for FIBCD1 gene

Protein Domains /
Families
for FIBCD1 gene

Function
for FIBCD1 gene

Pathways & Interactions
for FIBCD1 gene

Drugs & Compounds
for FIBCD1 gene

Transcripts
for FIBCD1 gene

Expression
for FIBCD1 gene

Orthologs
for FIBCD1 gene

Paralogs
for FIBCD1 gene

Genomic Variants
for FIBCD1 gene

Disorders / Diseases
for FIBCD1 gene

Publications
for FIBCD1 gene

Intellectual Property
for FIBCD1 gene

Products
for FIBCD1 gene