Aliases for FHL1 Gene
External Ids for FHL1 Gene
This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.[provided by RefSeq, Nov 2009]
GeneCards Summary for FHL1 Gene
FHL1 (Four And A Half LIM Domains 1) is a Protein Coding gene. Diseases associated with FHL1 include myopathy, reducing body, x-linked, childhood-onset and myopathy, x-linked, with postural muscle atrophy. Among its related pathways are Notch signaling pathway (KEGG). GO annotations related to this gene include ion channel binding. An important paralog of this gene is LDB3.
UniProtKB/Swiss-Prot for FHL1 Gene
May have an involvement in muscle development or hypertrophy