FHAD1 Gene
protein-coding GIFtS : 40
GCID: GC01 P015563
forkhead-associated (FHA) phosphopeptide binding domain...
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Aliasesfor FHAD1 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Forkhead-Associated (FHA) Phosphopeptide Binding Domain 1 1 2 KIAA19371 3 FHA Domain-Containing Protein 12 3 Forkhead-Associated Domain-Containing Protein 12
Export aliases for FHAD1 gene to outside databases Previous GC identifers: GC01P015309 GC01P015435 GC01P014095
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Summariesfor FHAD1 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section --
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Genomic Viewsfor FHAD1 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000001.10 NC_018912.1 NT_004610.19 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the FHAD1 gene promoter: STAT1 FOXF2 AML1a Lmo2 Evi-1 POU2F1 POU2F1a POU2F1b ARP-1 POU2F1c Other transcription factors Search SABiosciences Chromatin IP Primers for FHAD1 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FHAD1
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 1p36.21 Ensembl cytogenetic band: 1p36.21 HGNC cytogenetic band: 1p36.21 FHAD1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 1 GeneLoc Exon Structure
GeneLoc location for GC01P015563: view genomic region
(about GC identifiers )
Start:
15,573,768 bp from pter
End:
15,726,858 bp from pter
Size:
153,091 bases
Orientation:
plus strand
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Proteinsfor FHAD1 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: FHAD1_HUMAN, B1AJZ9 (See
protein sequence )Recommended Name: Forkhead-associated domain-containing protein 1 Size : 1412 amino acids; 161904 Da
Sequence caution : Sequence=BAC04126.1; Type=Erroneous initiation; Sequence=BAC04242.1; Type=Erroneous initiation;Sequence=BAC04913.1; Type=Erroneous initiation; Sequence=CAI21427.1; Type=Erroneous gene model prediction; Sequence=CAI21811.1; Type=Erroneous gene model prediction; Sequence=CAI23268.1; Type=Erroneous gene model prediction;
Secondary accessions : Q0P6F5 Q8N8D3 Q8N9T6 Q8NA05Alternative splicing : 3 isoforms : B1AJZ9-1 B1AJZ9-3 B1AJZ9-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for FHAD1: NX_B1AJZ9 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_B1AJZ9 FHAD1 Protein expression data from MOPED and PaxDb : About this image REFSEQ proteins: NP_443161.1 ENSEMBL proteins: ENSP00000410556 ENSP00000402241 ENSP00000365166 ENSP00000365165 ENSP00000436559 ENSP00000365163 ENSP00000399819 ENSP00000434909 ENSP00000318812 ENSP00000432147 ENSP00000351770 ENSP00000407615 ENSP00000365167 ENSP00000383868 ENSP00000322979 Human Recombinant Protein Products for FHAD1: FHAD1 Antibody Products: Assay Products for FHAD1:
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Protein
Domains / Familiesfor FHAD1 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
FHAD1 for domains About GeneDecksing 2 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry B1AJZ9 ProtoNet protein and cluster: B1AJZ9
UniProtKB/Swiss-Prot: FHAD1_HUMAN, B1AJZ9 Similarity : Contains 1 FHA domain
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Functionfor FHAD1 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Animal Models: Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for FHAD1 (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for FHAD1OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: FHAD1 (NM_052929 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FHAD1 Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FHAD1
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FHAD1
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Pathways & Interactionsfor FHAD1 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FHAD1
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Drugs & Compoundsfor FHAD1 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for FHAD1 Search CenterWatch for drugs/clinical trials and news about FHAD1
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Transcriptsfor FHAD1 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for FHAD1 gene: NM_052929.1 Unigene Cluster for FHAD1:
Forkhead-associated (FHA) phosphopeptide binding domain 1 Hs.659997 [show with all ESTs ] Unigene Representative Sequence: NM_052929 18/27 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 27 ): ENST00000436024 (uc001awa.1 ) ENST00000433640 ENST00000375998 ENST00000462113 ENST00000375996 ENST00000375997 ENST00000524761 ENST00000375995 ENST00000483694 ENST00000459961 ENST00000472131 ENST00000471347 ENST00000444385 (uc001awd.1 )ENST00000529606 ENST00000314668 ENST00000532408 ENST00000483120 (uc001awf.3 )ENST00000481324 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for FHAD1 (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for FHAD1OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: FHAD1 (NM_052929 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FHAD1 Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FHAD1
Additional cDNA sequence: AK057963.1 AK093300.1 AK093883.1 AK296920.1 AL833342.1 BC027293.2
15 DOTS entries : DT.97838968 DT.100021611
DT.121326161 DT.75200278 DT.100021612 DT.40256733 DT.95189534 DT.102828255 DT.75184874 DT.91698173 DT.97842334 DT.201695 DT.75158700 DT.95127519 DT.97762136 24/48 AceView cDNA sequences (see all 48 ):
AI285302 BC015238 BU686950 AA460155 AK093300 AI923455 BX279715 BQ014411 AI280612 AL833342 AX748041 AB067524 AK057963 BM998749 AW151194 W02141 BM913550 AX748350 BE274861 BM811207 BE888078 BX641070 BQ434769 AA722326 GeneLoc Exon Structure 5/10 Alternative Splicing Database (ASD) splice patterns (SP) for FHAD1 (see all 10 ) About this scheme ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b ^ 8a · 8b · 8c ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ SP1 :                     -     -   -                           SP2 :                                         -             SP3 :                                         -             SP4 :                                                     SP5 :             -   -       -     -   -   -                        
ExUns: 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26 ^ 27 ^ 28a · 28b ^ 29 ^ 30 ^ 31 ^ 32 ^ 33a · 33b · 33c ^ 34 SP1 : -                     -   -     -     -           SP2 : -                                         SP3 : -                   -   -   -   -   -   -   -           SP4 : -                   -     -         -           SP5 :                                        
ECgene alternative splicing isoforms for FHAD1
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Expression for FHAD1 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section FHAD1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: TGACTCTTCTAbout this image FHAD1 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table
See FHAD1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for FHAD1 SOURCE GeneReport for Unigene cluster: Hs.659997 SABiosciences Custom PCR Arrays for FHAD1 Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for FHAD1Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse / rat FHAD1 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat FHAD1 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat FHAD1 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FHAD1
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Orthologsfor FHAD1 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of chordates.
Orthologs for FHAD1 gene from 2/8 species (see all 8 ) About this table
ENSEMBL Gene Tree for FHAD1 (if available)TreeFam Gene Tree for FHAD1 (if available)
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Paralogsfor FHAD1 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section --
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Genomic Variantsfor FHAD1 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 1 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for FHAD1 (15573768 - 15726858 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 5 variations for FHAD1 4 CNVs : 74100 48142 48141 68085 1 Indel : 97299
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing FHAD1
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Disorders
/ Diseasesfor FHAD1 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section FHAD1 for disorders About MalaCards
FHAD1 for disorders About GeneDecksing Human Genome Epidemiology (HuGE) Navigator: FHAD1 (1 document)Export disorders for FHAD1 gene to outside databases
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Publicationsfor FHAD1 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for FHAD1 gene integrated from 9 sources : (articles sorted by number of sources associating them with FHAD1) Utopia : connect your pdf to the dynamic world of online information
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414) 1 , 2 Gregory S.G.... Bentley D.R. (2006) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. (PubMed id 11572484) 1 , 3 Nagase T....Ohara O. (2001) Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614) 1 Rose J.E....Uhl G.R. (2010) Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560) 1 Kimura K.... Sugano S. (2006) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 Gerhard D.S....Malek J. (2004) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 Strausberg R.L....Marra M.A. (2002)
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External Searches for FHAD1 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing FHAD1 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing FHAD1 gene
(According to HUGE )
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Specialized Databases showing FHAD1 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for FHAD1 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for FHAD1 gene: Search GeneIP for patents involving FHAD1 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor FHAD1 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
Browse OriGene Antibodies OriGene shRNA RFP for FHAD1 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for FHAD1 OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for FHAD1 Browse OriGene Protein Over-expression Lysates Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for FHAD1 Browse 3'-UTR reporter clones for miRNA target validation OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for FHAD1 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for FHAD1 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for FHAD1 OriGene Custom Protein Services for FHAD1 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FHAD1 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing FHAD1 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FHAD1 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat FHAD1 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat FHAD1 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat FHAD1
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FHAD1 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FHAD1
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Aliases for FHAD1
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Disorders / Diseases for FHAD1
Domains / Families for FHAD1
Drugs / Compounds for FHAD1
Expression for FHAD1
Function for FHAD1
Genomic Views for FHAD1
Intellectual Property for FHAD1
Orthologs for FHAD1
Paralogs for FHAD1
Pathways / Interactions for FHAD1
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Proteins for FHAD1
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Summaries for FHAD1
Transcripts for FHAD1
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