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Aliases for FHAD1 Gene

Aliases for FHAD1 Gene

  • Forkhead-Associated (FHA) Phosphopeptide Binding Domain 1 2 3 5
  • FHA Domain-Containing Protein 1 4
  • KIAA1937 4

External Ids for FHAD1 Gene

Previous GeneCards Identifiers for FHAD1 Gene

  • GC01P015309
  • GC01P015435
  • GC01P015563
  • GC01P014095

Summaries for FHAD1 Gene

GeneCards Summary for FHAD1 Gene

FHAD1 (Forkhead-Associated (FHA) Phosphopeptide Binding Domain 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FHAD1 Gene

Genomics for FHAD1 Gene

Regulatory Elements for FHAD1 Gene

Genomic Location for FHAD1 Gene

Chromosome:
1
Start:
15,236,602 bp from pter
End:
15,400,283 bp from pter
Size:
163,682 bases
Orientation:
Plus strand

Genomic View for FHAD1 Gene

Genes around FHAD1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FHAD1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FHAD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FHAD1 Gene

Proteins for FHAD1 Gene

  • Protein details for FHAD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    B1AJZ9-FHAD1_HUMAN
    Recommended name:
    Forkhead-associated domain-containing protein 1
    Protein Accession:
    B1AJZ9
    Secondary Accessions:
    • Q0P6F5
    • Q8N8D3
    • Q8N9T6
    • Q8NA05

    Protein attributes for FHAD1 Gene

    Size:
    1412 amino acids
    Molecular mass:
    161904 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC04126.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAC04242.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAC04913.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI21427.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI21811.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI23268.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for FHAD1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FHAD1 Gene

Proteomics data for FHAD1 Gene at MOPED

Post-translational modifications for FHAD1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FHAD1 Gene

Domains & Families for FHAD1 Gene

Protein Domains for FHAD1 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

B1AJZ9

UniProtKB/Swiss-Prot:

FHAD1_HUMAN :
  • Contains 1 FHA domain.
Domain:
  • Contains 1 FHA domain.
genes like me logo Genes that share domains with FHAD1: view

No data available for Gene Families for FHAD1 Gene

Function for FHAD1 Gene

Phenotypes for FHAD1 Gene

GenomeRNAi human phenotypes for FHAD1:
genes like me logo Genes that share phenotypes with FHAD1: view

Animal Model Products

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FHAD1 Gene

Localization for FHAD1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FHAD1 Gene COMPARTMENTS Subcellular localization image for FHAD1 gene
Compartment Confidence
cytosol 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FHAD1 Gene

Pathways & Interactions for FHAD1 Gene

SuperPathways for FHAD1 Gene

No Data Available

Interacting Proteins for FHAD1 Gene

Gene Ontology (GO) - Biological Process for FHAD1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FHAD1 Gene

Drugs & Compounds for FHAD1 Gene

No Compound Related Data Available

Transcripts for FHAD1 Gene

Unigene Clusters for FHAD1 Gene

Forkhead-associated (FHA) phosphopeptide binding domain 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FHAD1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b ^ 8a · 8b · 8c ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^
SP1: - - -
SP2: -
SP3: -
SP4:
SP5: - - - - - -
SP6:
SP7: - - -
SP8: -
SP9:
SP10:

ExUns: 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26 ^ 27 ^ 28a · 28b ^ 29 ^ 30 ^ 31 ^ 32 ^ 33a · 33b · 33c ^ 34
SP1: - - - - -
SP2: -
SP3: - - - - - - - -
SP4: - - - -
SP5:
SP6: - - - - - -
SP7:
SP8:
SP9:
SP10:

Relevant External Links for FHAD1 Gene

GeneLoc Exon Structure for
FHAD1
ECgene alternative splicing isoforms for
FHAD1

Expression for FHAD1 Gene

mRNA expression in normal human tissues for FHAD1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FHAD1 Gene

This gene is overexpressed in Testis (x21.5).

Protein differential expression in normal tissues from HIPED for FHAD1 Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (39.8) and Plasma (21.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FHAD1 Gene



SOURCE GeneReport for Unigene cluster for FHAD1 Gene Hs.659997

genes like me logo Genes that share expression patterns with FHAD1: view

Protein tissue co-expression partners for FHAD1 Gene

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for FHAD1 Gene

Orthologs for FHAD1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for FHAD1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FHAD1 35
  • 98.35 (n)
  • 97.89 (a)
FHAD1 36
  • 87 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FHAD1 36
  • 13 (a)
OneToOne
FHAD1 35
  • 80.87 (n)
  • 75.6 (a)
dog
(Canis familiaris)
Mammalia FHAD1 35
  • 81.49 (n)
  • 77.02 (a)
FHAD1 36
  • 13 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fhad1 16
Fhad1 35
  • 74.9 (n)
  • 68.97 (a)
Fhad1 36
  • 11 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FHAD1 36
  • 7 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 40 (a)
OneToMany
-- 36
  • 15 (a)
OneToMany
-- 36
  • 2 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Fhad1 35
  • 74.56 (n)
  • 68.32 (a)
chicken
(Gallus gallus)
Aves LOC771735 35
  • 57.54 (n)
  • 45.11 (a)
FHAD1 36
  • 3 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FHAD1 36
  • 6 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii FHAD1 (1 of 2) 36
  • 8 (a)
OneToMany
FHAD1 (2 of 2) 36
  • 5 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 8 (a)
OneToOne
Species with no ortholog for FHAD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FHAD1 Gene

ENSEMBL:
Gene Tree for FHAD1 (if available)
TreeFam:
Gene Tree for FHAD1 (if available)

Paralogs for FHAD1 Gene

genes like me logo Genes that share paralogs with FHAD1: view

No data available for Paralogs for FHAD1 Gene

Variants for FHAD1 Gene

Sequence variations from dbSNP and Humsavar for FHAD1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
VAR_046372 -
rs484060 -- 15,315,964(+) AGAAC(A/G)GCTGT intron-variant
rs525613 -- 15,281,728(-) gctgg(A/C)gtgca intron-variant
rs471308 -- 15,282,257(+) GTCCA(A/G)CCAGT intron-variant, upstream-variant-2KB
rs509161 -- 15,322,972(+) atggc(A/G)gtggc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FHAD1 Gene

Variant ID Type Subtype PubMed ID
nsv833425 CNV Gain 17160897
esv28285 CNV Loss 19812545
esv27394 CNV Gain 19812545
nsv517234 CNV Gain 19592680
esv2744297 CNV Deletion 23290073
esv2508152 CNV Insertion 19546169
nsv833536 CNV Loss 17160897
esv2671419 CNV Deletion 23128226
nsv460561 CNV Loss 19166990

Variation tolerance for FHAD1 Gene

Gene Damage Index Score: 18.24; 98.50% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FHAD1 Gene

HapMap Linkage Disequilibrium report
FHAD1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FHAD1 Gene

Disorders for FHAD1 Gene

Relevant External Links for FHAD1

Genetic Association Database (GAD)
FHAD1
Human Genome Epidemiology (HuGE) Navigator
FHAD1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FHAD1

No disorders were found for FHAD1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FHAD1 Gene

Publications for FHAD1 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48 67
  2. Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. (PMID: 11572484) Nagase T. … Ohara O. (DNA Res. 2001) 2 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for FHAD1 Gene

Sources for FHAD1 Gene

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