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FGGY Gene

protein-coding   GIFtS: 51
GCID: GC01P059762

FGGY Carbohydrate Kinase Domain Containing

  See FGGY-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
FGGY Carbohydrate Kinase Domain Containing1 2
FGGY Carbohydrate Kinase Domain-Containing Protein2
EC 2.7.1.-3
EC 2.7.18

External Ids:    HGNC: 256101   Entrez Gene: 552772   Ensembl: ENSG000001724567   OMIM: 6113705   UniProtKB: Q96C113   
ORGUL members:         

Export aliases for FGGY gene to outside databases

Previous GC identifers: GC01P059535 GC01P057873


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for FGGY Gene:
This gene encodes a protein that phosphorylates carbohydrates such as ribulose, ribitol, and L-arabinitol.
Genome-wide association studies in some populations have found an association between polymorphisms in this gene
and sporadic amyotrophic lateral sclerosis, but studies of other populations have not been able to replicate this
association. Alternative splicing results in multiple transcript variants. (provided by RefSeq, May 2013)

GeneCards Summary for FGGY Gene:
FGGY (FGGY carbohydrate kinase domain containing) is a protein-coding gene. Diseases associated with FGGY include amyotrophic lateral sclerosis. GO annotations related to this gene include phosphotransferase activity, alcohol group as acceptor and kinase activity.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_032977.10  
Regulatory elements:
   Regulatory transcription factor binding sites in the FGGY gene promoter:
         LHX3b/Lhx3b   p53   HNF-4alpha1   S8   POU2F1   POU2F1a   HSF2   Sox9   LHX3a/Lhx3a   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFGGY promoter sequence
   Search Chromatin IP Primers for FGGY

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FGGY


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p32.1   Ensembl cytogenetic band:  1p32.1   HGNC cytogenetic band: 1p32.1

FGGY Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FGGY gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P059762:  view genomic region     (about GC identifiers)

Start:
59,762,310 bp from pter      End:
60,233,347 bp from pter
Size:
471,038 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: FGGY_HUMAN, Q96C11 (See protein sequence)
Recommended Name: FGGY carbohydrate kinase domain-containing protein  
Size: 551 amino acids; 59993 Da
Developmental stage: Expressed in fetal brain (at protein level)
Sequence caution: Sequence=AAH14947.1; Type=Erroneous initiation;
Secondary accessions: B1AK92 B1AK93 B1AK94 B2RDR8 D3DQ56 Q9HA63
Alternative splicing: 5 isoforms:  Q96C11-1   Q96C11-2   Q96C11-4   Q96C11-3   Q96C11-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FGGY: NX_Q96C11

Explore proteomics data for FGGY at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • 4 DME Specific Peptides for FGGY (Q96C11)
     GTGSVRA  GFDATCSLVV  ASLIDAHAGG  WPDFHGNRSPLAD 


    See FGGY Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001106882.1  NP_001231643.1  NP_001265153.1  NP_060761.3  

    ENSEMBL proteins: 
     ENSP00000463260   ENSP00000406607   ENSP00000360262   ENSP00000305922   ENSP00000403425  
     ENSP00000360256   ENSP00000360254  

    FGGY Human Recombinant Protein Products:

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    Browse Sino Biological Recombinant Proteins
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    Cloud-Clone Corp. Proteins for FGGY

     
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    Search eBioscience for ELISAs for FGGY 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR018485 Carb_kinase_FGGY_C
     IPR006003 Carb_kinase_FGGY-rel
     IPR018484 Carb_kinase_FGGY_N

    Graphical View of Domain Structure for InterPro Entry Q96C11

    ProtoNet protein and cluster: Q96C11

    UniProtKB/Swiss-Prot: FGGY_HUMAN, Q96C11
    Similarity: Belongs to the FGGY kinase family


    Find genes that share domains with FGGY           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Enzyme Numbers (IUBMB): EC 2.7.1.-1 EC 2.7.12

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0016301kinase activity IEA--
    GO:0016773phosphotransferase activity, alcohol group as acceptor IEA--
         
    Find genes that share ontologies with FGGY           About GenesLikeMe


    Phenotypes:
         1 MGI phenotypic allele for Fggy (no phenotypes)

    Find genes that share phenotypes with FGGY           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FGGY
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    miRNA
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    miRTarBase miRNAs that target FGGY:
    hsa-mir-26b-5p (MIRT029931)

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    Browse Sino Biological Human cDNA Clones
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    Addgene plasmids for FGGY 

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    eBioscience FlowRNA Probe Sets ( VA6-13791) for FGGY 


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--

    Find genes that share ontologies with FGGY           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FGGY
    Interactions:

        Search GeneGlobe Interaction Network for FGGY

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    Selected Interacting proteins for FGGY (Q96C113 ENSP000003602624) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CSNK1G2P783683I2D: score=2 
    APIPQ96GX93I2D: score=1 
    PSMD13Q9UNM63I2D: score=1 
    MMS19ENSP000003598184STRING: ENSP00000359818
    IPO11ENSP000003869924STRING: ENSP00000386992
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process IEA--
    GO:0008219cell death IEA--
    GO:0070050neuron cellular homeostasis IMP17671248

    Find genes that share ontologies with FGGY           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FGGY



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for FGGY gene (4 alternative transcripts): 
    NM_001113411.1  NM_001244714.1  NM_001278224.1  NM_018291.3  

    Unigene Cluster for FGGY:

    FGGY carbohydrate kinase domain containing
    Hs.444301  [show with all ESTs]
    Unigene Representative Sequence: AK090568
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19):
    ENST00000582567 ENST00000413489 ENST00000474476 ENST00000462744 ENST00000371218(uc009wac.3 uc001czi.4)
    ENST00000495718(uc001czg.2) ENST00000583635 ENST00000303721(uc001czm.4)
    ENST00000430447(uc001czh.2) ENST00000371212(uc001czl.4) ENST00000475949
    ENST00000485720 ENST00000371210 ENST00000493891 ENST00000466791 ENST00000476939
    ENST00000472783 ENST00000471169
    miRNA
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      QuantiTect SYBR Green Assays in human, mouse, rat FGGY
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    Additional mRNA sequence: 

    AK001848.1 AK022237.1 AK054842.1 AK090568.1 AK315649.1 BC000610.2 BC014947.1 BX647626.1 

    20 DOTS entries:

    DT.437862  DT.95339918  DT.100044268  DT.121326626  DT.95166987  DT.100044405  DT.100772917  DT.100779440 
    DT.100779443  DT.100044403  DT.100739393  DT.100727168  DT.75102673  DT.100779445  DT.100834153  DT.92456033 
    DT.95147933  DT.95166828  DT.95094649  DT.97765991 

    Selected AceView cDNA sequences (see all 142):

    BU149797 CB138001 AK054842 BC042048 CA311928 CR599846 BM855106 BQ934625 
    AU121672 AI278286 CR607394 BX358874 BQ644899 NM_018291 AK022237 BM726496 
    BM688624 BQ892439 BX382565 CR609789 BC014947 BU556699 BQ440371 CR623798 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FGGY expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    FGGY Expression
    About this image


    FGGY expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Epithelial Cells
             Presumptive Podocytes Podocyte Layer
     
     Kidney (Urinary System)
             Presumptive Podocytes Podocyte Layer
     
     Liver (Hepatobiliary System)
    FGGY Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FGGY Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.444301

    UniProtKB/Swiss-Prot: FGGY_HUMAN, Q96C11
    Tissue specificity: Expressed in kidney, lung and small intestine and to a lower extent in liver and detected in
    cerebrospinal fluid (at protein level)

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for FGGY gene from Selected species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fggy1 , 5 FGGY carbohydrate kinase domain containing1, 5 88.16(n)1
    91.44(a)1
      4 (43.83 cM)5
    755781  NM_001113412.11  NP_001106883.11 
     955575075 
    chicken
    (Gallus gallus)
    Aves FGGY1 FGGY carbohydrate kinase domain containing 75.9(n)
    77.78(a)
      772383  XM_001235528.2  XP_001235529.2 
    lizard
    (Anolis carolinensis)
    Reptilia FGGY6
    FGGY carbohydrate kinase domain containing
    73(a)
    1 ↔ 1
    4(101520806-101724421)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia fggy1 FGGY carbohydrate kinase domain containing 69.98(n)
    73.16(a)
      100145330  NM_001126804.1  NP_001120276.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.197402 Transcribed sequence with weak similarity to protein more 73.08(n)    AL923283.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG115941 CG11594 54.98(n)
    50(a)
      38473  NM_168046.2  NP_728918.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes (YDR109C)4
    YDR109C1
    Putative kinase4
    YDR109C1
    49.13(n)1
    42.36(a)1
      4(675667-673520)4
    8516871, 4  NP_010394.31  NP_010394.14 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G303101 AT4G30310 53.83(n)
    50.18(a)
      829154  NM_119177.4  NP_194760.2 
    rice
    (Oryza sativa)
    Liliopsida AK066421.12   -- 71.8(n)    AK066421.1 


    ENSEMBL Gene Tree for FGGY (if available)
    TreeFam Gene Tree for FGGY (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FGGY gene
    1 SIMAP similar gene for FGGY using alignment to 4 protein entries:     FGGY_HUMAN (see all proteins):
    FLJ10986

    Find genes that share paralogs with FGGY           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FGGY (see all 9701)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs753433171,2
    C,F--57871712(+) AAATTA/GTTTTT 2 -- us2k11Minor allele frequency- G:0.04NA 120
    rs1387541571,2
    --57871820(+) GTTATC/TAGGTT 3 -- us2k10--------
    rs66568861,2
    C,F,H--57871835(+) CTCATA/GCAATA 3 -- us2k15Minor allele frequency- G:0.08NS EA WA 536
    rs1831926401,2
    --57871837(+) CATACA/GATAGA 3 -- us2k10--------
    rs1488363131,2
    --57871902(+) GGTCTA/GGAGGG 3 -- us2k10--------
    rs1874411471,2
    --57871920(+) TATTGA/GTTGGT 3 -- us2k10--------
    rs1434207261,2
    --57871938(+) CTCCTA/GCATTA 3 -- us2k10--------
    rs556804531,2
    C,F--57871944(+) CATTAG/CGAATC 3 -- us2k12Minor allele frequency- C:0.04WA 120
    rs1480097501,2
    --57871952(+) ATCCAC/TGCTTC 3 -- us2k10--------
    rs1169714311,2
    C,F--57871953(+) TCCACG/ACTTCT 3 -- us2k11Minor allele frequency- A:0.01EA 120

    HapMap Linkage Disequilibrium report for FGGY (59762310 - 60012310 bp, first 250kb of FGGY)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for FGGY (see all 28):    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv820893CNV Deletion20802225
    esv2748874CNV Deletion23290073
    esv2663896CNV Deletion23128226
    esv2675145CNV Deletion23128226
    esv2657989CNV Deletion23128226
    esv2674836CNV Deletion23128226
    esv2421406CNV Deletion20811451
    esv2748885CNV Deletion23290073
    esv1430411CNV Insertion17803354
    esv271999CNV Insertion20981092

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FGGY
    DNA2.0 Custom Variant and Variant Library Synthesis for FGGY

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611370    OMIM disorders: --

    UniProtKB/Swiss-Prot: FGGY_HUMAN, Q96C11
  • Amyotrophic lateral sclerosis (ALS) [MIM:105400]: A neurodegenerative disorder affecting upper motor
    neurons in the brain and lower motor neurons in the brain stem and spinal cord, resulting in fatal paralysis.
    Sensory abnormalities are absent. The pathologic hallmarks of the disease include pallor of the corticospinal
    tract due to loss of motor neurons, presence of ubiquitin-positive inclusions within surviving motor neurons, and
    deposition of pathologic aggregates. The etiology of amyotrophic lateral sclerosis is likely to be
    multifactorial, involving both genetic and environmental factors. The disease is inherited in 5-10% of the cases.
    Note=Disease susceptibility is associated with variations affecting the gene represented in this entry

  • 1 disease for FGGY:    
    About MalaCards
    amyotrophic lateral sclerosis

    1 disease from the University of Copenhagen DISEASES database for FGGY:
    Amyotrophic lateral sclerosis

    Find genes that share disorders with FGGY           About GenesLikeMe

    Genetic Association Database (GAD): FGGY
    Human Genome Epidemiology (HuGE) Navigator: FGGY (4 documents)

    Export disorders for FGGY gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FGGY gene, integrated from 10 sources (see all 21):
    (articles sorted by number of sources associating them with FGGY)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Whole-genome analysis of sporadic amyotrophic lateral sclerosis. (PubMed id 17671248)1, 2, 3, 4 Dunckley T.... Stephan D.A. (N. Engl. J. Med. 2007)
    2. No evidence of association of FLJ10986 and ITPR2 with ALS in a large German cohort. (PubMed id 19464757)1, 4 FernA!ndez-Santiago R....Gasser T. (Neurobiol. Aging 2011)
    3. Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women. (PubMed id 21507922)1, 4 Ramsuran V....Ndung'u T. (Clin. Infect. Dis. 2011)
    4. Analysis of DPP6 and FGGY as candidate genes for amyotrophic lateral sclerosis. (PubMed id 20001489)1, 4 Daoud H....Rouleau G.A. (Amyotroph Lateral Scler 2010)
    5. Genomewide association study of movement-related adverse antipsychotic effects. (PubMed id 19875103)1, 4 Aberg K....van den Oord E.J. (Biol. Psychiatry 2010)
    6. A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis. (PubMed id 19193627)1, 4 ChiA^ A....Traynor B.J. (Hum. Mol. Genet. 2009)
    7. Clinical and genetic features of patients with sporadic amyotrophic lateral sclerosis in south-west China. (PubMed id 19922123)1, 4 Fang D.F....Shang H.F. (Amyotroph Lateral Scler 2009)
    8. Analysis of FGGY as a risk factor for sporadic amyotrophic lateral sclerosis. (PubMed id 19922138)1, 4 Van Es M.A....Van Den Berg L.H. (Amyotroph Lateral Scler 2009)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    10. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55277 HGNC: 25610 AceView: FLJ10986 Ensembl:ENSG00000172456 euGenes: HUgn55277
    ECgene: FGGY H-InvDB: FGGY

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for FGGY Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FGGY gene:
    Search GeneIP for patents involving FGGY

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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