Aliases for FGFRL1 Gene
Aliases for FGFRL1 Gene
External Ids for FGFRL1 Gene
- HGNC: 3693
- Entrez Gene: 53834
- Ensembl: ENSG00000127418
- OMIM: 605830
- UniProtKB: Q8N441
Previous GeneCards Identifiers for FGFRL1 Gene
- GC04M001066
- GC04P000994
- GC04P000996
Summaries for FGFRL1 Gene
-
The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for FGFRL1 Gene
FGFRL1 (Fibroblast Growth Factor Receptor Like 1) is a Protein Coding gene. Diseases associated with FGFRL1 include Chromosome 4P Deletion. Among its related pathways are VEGF Signaling Pathway and Signaling by FGFR2. Gene Ontology (GO) annotations related to this gene include heparin binding and fibroblast growth factor-activated receptor activity.
UniProtKB/Swiss-Prot for FGFRL1 Gene
-
Has a negative effect on cell proliferation.
Additional gene information for FGFRL1 Gene
- Monarch Initiative
- Search for FGFRL1 at DataMed
- Search for FGFRL1 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FGFRL1 Gene
Genomics for FGFRL1 Gene
GeneHancer (GH) Regulatory Elements for FGFRL1 Gene
Promoters and enhancers for FGFRL1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around FGFRL1 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the FGFRL1 gene promoter:
Regulatory Element Products
Genomic Locations for FGFRL1 Gene
Genomic Locations for FGFRL1 Gene
- chr4:1,009,936-1,026,898
- (GRCh38/hg38)
- Size:
- 16,963 bases
- Orientation:
- Plus strand
- chr4:1,003,724-1,020,686
- (GRCh37/hg19)
Genomic View for FGFRL1 Gene
Genes around FGFRL1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 4p16.3 by Ensembl
- 4p16.3 by Entrez Gene
- 4p16.3 by HGNC
FGFRL1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FGFRL1 Gene
Proteins for FGFRL1 Gene
-
Protein details for FGFRL1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8N441-FGRL1_HUMAN
- Recommended name:
- Fibroblast growth factor receptor-like 1
- Protein Accession:
- Q8N441
- B2RAU9
- Q6PJN1
- Q9BXN7
- Q9H4D7
Protein attributes for FGFRL1 Gene
- Size:
- 504 amino acids
- Molecular mass:
- 54537 Da
- Quaternary structure:
-
- Interacts with FGF2 with a low affinity.
Protein Expression for FGFRL1 Gene
Post-translational modifications for FGFRL1 Gene
- Glycosylation at posLast=111111, posLast=231231, posLast=255255, and posLast=293293
Other Protein References for FGFRL1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for FGFRL1 (FGF R5/FGFRL1)
-
Custom Antibody ServicesOriGene Antibodies for FGFRL1
- Novus Biologicals Antibodies for FGFRL1
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Abcam antibodies for FGFRL1
-
Cloud-Clone Corp. Antibodies for FGFRL1
- Invitrogen Antibodies for FGFRL1
- GeneTex FGFRL1 antibody for FGFRL1
- Sino Biological Antibodies for FGFRL1
Protein Products
- R&D Systems Proteins and Enzymes for FGFRL1 (FGF R5/FGFRL1)
-
OriGene Purified Proteins for FGFRL1
- Search Origene for MassSpec and Protein Over-expression Lysates for FGFRL1
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- Sino Biological Cell Lysates for FGFRL1
- Sino Biological Recombinant Proteins for FGFRL1
-
Cloud-Clone Corp. Proteins for FGFRL1
- Search GeneTex for Proteins for FGFRL1
-
ProSci Proteins for FGFRL1
-
Abcam proteins for FGFRL1
Assay Products
-
Cloud-Clone Corp. Assay Kits for FGFRL1
No data available for DME Specific Peptides for FGFRL1 Gene
Domains & Families for FGFRL1 Gene
Gene Families for FGFRL1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
- Predicted secreted proteins
- Transporters
Protein Domains for FGFRL1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for FGFRL1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for FGFRL1 Gene
Function for FGFRL1 Gene
Molecular function for FGFRL1 Gene
- UniProtKB/Swiss-Prot Function:
- Has a negative effect on cell proliferation.
Phenotypes From GWAS Catalog for FGFRL1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005007 | fibroblast growth factor-activated receptor activity | IDA | 12813049 |
| GO:0008201 | heparin binding | IMP | 18061161 |
| GO:0017134 | fibroblast growth factor binding | IEA | -- |
Phenotypes for FGFRL1 Gene
- MGI mutant phenotypes for FGFRL1:
-
inferred from 4 alleles
- nervous system phenotype
- normal phenotype
- homeostasis/metabolism phenotype
- respiratory system phenotype
- muscle phenotype
- cardiovascular system phenotype
- mortality/aging
- cellular phenotype
- behavior/neurological phenotype
- growth/size/body region phenotype
- embryo phenotype
- hematopoietic system phenotype
- skeleton phenotype
- renal/urinary system phenotype
- craniofacial phenotype
- GenomeRNAi human phenotypes for FGFRL1:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for FGFRL1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for FGFRL1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FGFRL1 gene
- Search ViGene Biosciences for FGFRL1
CRISPR Products
-
OriGene CRISPR knockouts for FGFRL1
- genomics-online: gRNA clones - Search results for 143 available FGFRL1 gene related products
- Overview of 143 available FGFRL1 gene related products
- Applied Biological Materials CRISPR for FGFRL1
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Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for FGFRL1
- GenScript: Design CRISPR guide RNA sequences for FGFRL1
miRNA for FGFRL1 Gene
- miRTarBase miRNAs that target FGFRL1
-
- hsa-mir-210-3p (MIRT000153)
- hsa-mir-335-5p (MIRT018248)
- hsa-let-7b-5p (MIRT052346)
- hsa-mir-6818-5p (MIRT121074)
- hsa-mir-6867-5p (MIRT121075)
- hsa-mir-21-5p (MIRT163939)
- hsa-mir-103a-3p (MIRT163941)
- hsa-mir-107 (MIRT163942)
- hsa-mir-574-5p (MIRT329252)
- hsa-mir-1304-5p (MIRT329254)
- hsa-mir-1827 (MIRT329255)
- hsa-mir-4310 (MIRT329256)
- hsa-mir-3659 (MIRT329257)
- hsa-mir-4658 (MIRT329258)
- hsa-mir-6790-5p (MIRT329260)
- hsa-mir-7157-5p (MIRT329261)
- hsa-mir-6765-5p (MIRT545441)
- hsa-mir-4793-3p (MIRT545442)
- hsa-mir-3130-3p (MIRT545443)
- hsa-mir-140-5p (MIRT733353)
miRNA Products
- Search ViGene Biosciences for FGFRL1
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for FGFRL1
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- genomics-online: shRNA clones - Search results for 143 available FGFRL1 gene related products
- Overview of 143 available FGFRL1 gene related products
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ViGene Biosciences ready-to-package AAV shRNAs for FGFRL1 gene
Clone Products
-
OriGene ORF clones in human for FGFRL1
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- VectorBuilder custom plasmid, inducible vectors for FGFRL1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FGFRL1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for FGFRL1
- Applied Biological Materials Clones for FGFRL1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
- R&D Systems cDNA Clones for FGFRL1 (FGF R5/FGFRL1)
Cell Line Products
-
Horizon Cell Lines for FGFRL1
-
ViGene Biosciences adenoviral particle packaged cDNA for FGFRL1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FGFRL1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FGFRL1 gene
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for FGFRL1 Gene
Localization for FGFRL1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for FGFRL1 Gene
- Membrane; Single-pass type I membrane protein. Note=Predominantly localized in the plasma membrane but also detected in the Golgi and in secretory vesicles.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| golgi apparatus | 5 |
| extracellular | 2 |
| endoplasmic reticulum | 2 |
| peroxisome | 1 |
- Vesicles (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005794 | Golgi apparatus | IDA | 18061161 |
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
| GO:0030133 | transport vesicle | IDA | 18061161 |
Pathways & Interactions for FGFRL1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Negative regulation of FGFR3 signaling | ||
| 2 | VEGF Signaling Pathway | ||
| 3 | MAPK Signaling: Mitogen Stimulation Pathway | ||
| 4 | mTOR signaling pathway (KEGG) | ||
| 5 | Signaling by GPCR | ||
Pathways by source for FGFRL1 Gene
4 Reactome pathways for FGFRL1 Gene
1 PharmGKB pathway for FGFRL1 Gene
2 R&D Systems pathways for FGFRL1 Gene
Interacting Proteins for FGFRL1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001501 | skeletal system development | IEA | -- |
| GO:0003179 | heart valve morphogenesis | IEA | -- |
| GO:0008285 | negative regulation of cell proliferation | IEA | -- |
| GO:0008543 | fibroblast growth factor receptor signaling pathway | TAS | -- |
| GO:0034446 | NOT substrate adhesion-dependent cell spreading | IDA | 18061161 |
No data available for SIGNOR curated interactions for FGFRL1 Gene
Drugs & Compounds for FGFRL1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| LY2874455 | Pharma | FGF/FGFR Inhibitor | 0 |
(1) ApexBio Compounds for FGFRL1 Gene
| Compound | Action | Cas Number |
|---|---|---|
| LY2874455 | FGF/FGFR Inhibitor | 1254473-64-7 |
Transcripts for FGFRL1 Gene
mRNA/cDNA for FGFRL1 Gene
- (4) REFSEQ mRNAs :
- (12) Additional mRNA sequences :
- (157) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FGFRL1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for FGFRL1
- genomics-online: gRNA clones - Search results for 143 available FGFRL1 gene related products
- Overview of 143 available FGFRL1 gene related products
- Applied Biological Materials CRISPR for FGFRL1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for FGFRL1
- GenScript: Design CRISPR guide RNA sequences for FGFRL1
miRNA Products
- Search ViGene Biosciences for FGFRL1
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for FGFRL1
- Browse OriGene Inhibitory RNA Products For FGFRL1
- genomics-online: shRNA clones - Search results for 143 available FGFRL1 gene related products
- Overview of 143 available FGFRL1 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for FGFRL1 gene
Clone Products
-
OriGene ORF clones in human for FGFRL1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for FGFRL1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for FGFRL1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FGFRL1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for FGFRL1
- Applied Biological Materials Clones for FGFRL1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
- R&D Systems cDNA Clones for FGFRL1 (FGF R5/FGFRL1)
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | · | 9c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||||
| SP5: | - |
Expression for FGFRL1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Bone (Muscoskeletal System)
-
Kidney (Urinary System)
- S-shaped Body Distal Cells S-shaped Body Distal Segment
- S-shaped Body Proximal Cells S-shaped Body Proximal Segment
- Proximal Renal Vesicle Cells Renal Vesicle
- S-shaped Body Medial Cells S-shaped Body Medial Segment
- Distal Renal Vesicle Cells Renal Vesicle
-
Lung (Respiratory System)
- Chondrocytes Tracheal Cartilage
- Tracheal Cartilage
- Brain (Nervous System)
- Cartilage (Muscoskeletal System)
- Neural Tube (Nervous System)
- Limb (Muscoskeletal System)
-
Heart (Cardiovascular System)
- Cushion Mesenchymal Cells Endocardium
-
Glial Cells
- Protoplasmic Astrocyte Cells Neocortex
- Gut Tube (Gastrointestinal Tract)
- Eye (Sensory Organs)
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for FGFRL1 Gene
NURSA nuclear receptor signaling pathways regulating expression of FGFRL1 Gene:
FGFRL1SOURCE GeneReport for Unigene cluster for FGFRL1 Gene:
Hs.193326mRNA Expression by UniProt/SwissProt for FGFRL1 Gene:
Q8N441-FGRL1_HUMAN
Tissue specificity:
Expressed preferentially in cartilaginous tissues and pancreas. Highly expressed in the liver, kidney, heart, brain and skeletal muscle. Weakly expressed in the lung, small intestine and spleen.
Evidence on tissue expression from TISSUES for FGFRL1 Gene
- Nervous system(4.2)
Primer Products
-
OriGene qPCR primer pairs for FGFRL1
-
OriGene qPCR primer pairs and template standards for FGFRL1
- genomics-online: primer clones - Search results for 143 available FGFRL1 gene related products
- Overview of 143 available FGFRL1 gene related products
No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for FGFRL1 Gene
Orthologs for FGFRL1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | FGFRL1 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | LOC102151155 33 |
|
||
| FGFRL1 34 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Fgfrl1 34 16 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Fgfrl1 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | FGFRL1 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | FGFRL1 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | FGFRL1 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | FGFRL1 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | fgfrl1 33 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.17937 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | fgfrl1a 34 33 |
|
OneToOne | |
| zgc64084 33 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | CG31431 34 |
|
OneToOne | |
| worm (Caenorhabditis elegans) |
Secernentea | igcm-4 34 33 |
|
OneToOne | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToOne |
- Species where no ortholog for FGFRL1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chimpanzee (Pan troglodytes)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for FGFRL1 Gene
(6) SIMAP similar genes for FGFRL1 Gene using alignment to 4 proteins:
No data available for Paralogs for FGFRL1 Gene
Variants for FGFRL1 Gene
| SNP ID | Clin | Chr 04 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000129345 | -- | 1,017,283(+) | C/T | intron_variant | |
| rs1000184487 | -- | 1,023,125(+) | C/G | intron_variant | |
| rs1000284494 | -- | 1,010,887(+) | T/C | upstream_transcript_variant | |
| rs1000397629 | -- | 1,014,383(+) | C/T | intron_variant | |
| rs1000886618 | -- | 1,011,982(+) | C/T | 5_prime_UTR_variant, genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv2703n106 | CNV | deletion | 24896259 |
| esv28049 | CNV | loss | 19812545 |
| nsv1003219 | CNV | gain | 25217958 |
| nsv1008352 | CNV | gain | 25217958 |
| nsv1073282 | CNV | deletion | 25765185 |
| nsv1120469 | CNV | tandem duplication | 24896259 |
| nsv1133572 | CNV | deletion | 24896259 |
| nsv469998 | CNV | loss | 18288195 |
| nsv593226 | CNV | loss | 21841781 |
| nsv593228 | CNV | loss | 21841781 |
| nsv593231 | CNV | gain | 21841781 |
| nsv593233 | CNV | loss | 21841781 |
| nsv593234 | CNV | loss | 21841781 |
| nsv593235 | CNV | loss | 21841781 |
| nsv822425 | CNV | loss | 20364138 |
| nsv822428 | CNV | gain | 20364138 |
| nsv950328 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
57% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
7.40;
81.82% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for FGFRL1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FGFRL1 Gene
Disorders for FGFRL1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| chromosome 4p deletion |
|
|
Search FGFRL1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for FGFRL1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for FGFRL1 Gene
Publications for FGFRL1 Gene
- Characterization of FGFRL1, a novel fibroblast growth factor (FGF) receptor preferentially expressed in skeletal tissues. (PMID: 12813049) Trueb B … Wiedemann M (The Journal of biological chemistry 2003) 3 4 22 58
- A novel fibroblast growth factor receptor-5 preferentially expressed in the pancreas(1). (PMID: 11267671) Kim I … Koh GY (Biochimica et biophysica acta 2001) 3 4 22 58
- Identification of a new fibroblast growth factor receptor, FGFR5. (PMID: 11418238) Sleeman M … Murison JG (Gene 2001) 3 4 22 58
- Biology of FGFRL1, the fifth fibroblast growth factor receptor. (PMID: 21080029) Trueb B (Cellular and molecular life sciences : CMLS 2011) 2 3 58
- A Large-scale genetic association study of esophageal adenocarcinoma risk. (PMID: 20453000) Liu CY … Christiani DC (Carcinogenesis 2010) 3 44 58
Products for FGFRL1 Gene
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- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
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- Cloud-Clone Corp. Antibodies for FGFRL1
- Cloud-Clone Corp. Proteins for FGFRL1
- Cloud-Clone Corp. Assay Kits for FGFRL1
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for FGFRL1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ApexBio compounds for FGFRL1
- Cyagen custom Knockout/knockin (KOKI) mouse models for FGFRL1
- VectorBuilder custom plasmid, inducible vectors for FGFRL1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FGFRL1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for FGFRL1
- antibodies-online: Search results for 84 available FGFRL1 Antibodies ranked by validation data
- Compare Top FGFRL1 Antibodies
- antibodies-online: Search results for 10 available FGFRL1 Elisa Kits ranked by validation data
- Compare Top FGFRL1 Elisa Kits
- antibodies-online: Search results for 19 available FGFRL1 Proteins ranked by validation data
- Compare Top FGFRL1 Proteins
- GeneTex FGFRL1 antibody for FGFRL1
- Search GeneTex for Proteins for FGFRL1
- ViGene Biosciences adenoviral particle packaged cDNA for FGFRL1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for FGFRL1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for FGFRL1 gene
- Search ViGene Biosciences for FGFRL1
- Horizon Cell Lines for FGFRL1
- genomics-online: cdna clones - Search results for 143 available FGFRL1 gene related products
- Overview of 143 available FGFRL1 gene related products
- orf clones - Search results for 143 available FGFRL1 gene related products
- Overview of 143 available FGFRL1 gene related products
- genomics-online: gRNA clones - Search results for 143 available FGFRL1 gene related products
- Overview of 143 available FGFRL1 gene related products
- genomics-online: primer clones - Search results for 143 available FGFRL1 gene related products
- Overview of 143 available FGFRL1 gene related products
- genomics-online: shRNA clones - Search results for 143 available FGFRL1 gene related products
- Overview of 143 available FGFRL1 gene related products
Sources for FGFRL1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew