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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FGFR1OP2 Gene

protein-coding   GIFtS: 54
GCID: GC12P027091

FGFR1 Oncogene Partner 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
FGFR1 Oncogene Partner 21 2
HSPC123-like2
WIT3.02
Fibroblast Growth Factor Receptor 1 Oncogene Partner 22
Wound Inducible Transcript 3.02

External Ids:    HGNC: 230981   Entrez Gene: 261272   Ensembl: ENSG000001117907   OMIM: 6088585   UniProtKB: Q9NVK53   

Export aliases for FGFR1OP2 gene to outside databases

Previous GC identifers: GC00U912750 GC12P026983 GC12P026984 GC12P026861


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for FGFR1OP2 Gene: 
FGFR1OP2 (FGFR1 oncogene partner 2) is a protein-coding gene. Diseases associated with FGFR1OP2 include cerebral cavernous malformations 3, and cavernous malformation, and among its related super-pathways are Signaling by FGFR1 mutants and Signaling by FGFR. GO annotations related to this gene include protein homodimerization activity. An important paralog of this gene is SIKE1.

UniProtKB/Swiss-Prot: FGOP2_HUMAN, Q9NVK5
Function: May be involved in wound healing pathway (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.2  NT_009714.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FGFR1OP2 gene promoter:
         Elk-1   AML1a   Nkx2-2   HSF1 (long)   HNF-3beta   GATA-2   Egr-4   FAC1   HFH-1   HSF1short   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): FGFR1OP2 promoter sequence
   Search SABiosciences Chromatin IP Primers for FGFR1OP2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FGFR1OP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p11.23   Ensembl cytogenetic band:  12p11.23   HGNC cytogenetic band: 12p12.1

FGFR1OP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FGFR1OP2 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P027091:  view genomic region     (about GC identifiers)

Start:
27,091,305 bp from pter      End:
27,119,583 bp from pter
Size:
28,279 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: FGOP2_HUMAN, Q9NVK5 (See protein sequence)
Recommended Name: FGFR1 oncogene partner 2  
Size: 253 amino acids; 29426 Da
Subcellular location: Cytoplasm (By similarity)
Sequence caution: Sequence=AAF29087.1; Type=Frameshift; Positions=61, 67, 72, 91; Sequence=CAB56012.1;
Type=Frameshift; Positions=189;
Secondary accessions: Q6R955 Q8N5L7 Q9P034 Q9UFK8
Alternative splicing: 3 isoforms:  Q9NVK5-1   Q9NVK5-2   Q9NVK5-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FGFR1OP2: NX_Q9NVK5

Explore proteomics data for FGFR1OP2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NVK5

  • FGFR1OP2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    FGFR1OP2 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001165358.1  NP_001165359.1  NP_056448.1  

    ENSEMBL proteins: 
     ENSP00000229395   ENSP00000441144   ENSP00000437556   ENSP00000323763  
    Reactome Protein details: Q9NVK5
    Human Recombinant Protein Products for FGFR1OP2: 
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for FGFR1OP2 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ----
    GO:0005829cytosol TAS--

    FGFR1OP2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR008555 SIKE

    Graphical View of Domain Structure for InterPro Entry Q9NVK5

    ProtoNet protein and cluster: Q9NVK5

    UniProtKB/Swiss-Prot: FGOP2_HUMAN, Q9NVK5
    Similarity: Belongs to the SIKE family


    FGFR1OP2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FGOP2_HUMAN, Q9NVK5
    Function: May be involved in wound healing pathway (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0042803protein homodimerization activity IEA--
         
    FGFR1OP2 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for FGFR1OP2:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for FGFR1OP2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for FGFR1OP2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FGFR1OP2 
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    8/23 QIAGEN miScript miRNA Assays for microRNAs that regulate FGFR1OP2 (see all 23):
    hsa-miR-495 hsa-miR-520d-5p hsa-miR-1297 hsa-miR-1244 hsa-miR-7-1* hsa-miR-558 hsa-miR-129-3p hsa-miR-129*
    SwitchGear 3'UTR luciferase reporter plasmidFGFR1OP2 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for FGFR1OP2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Signaling by FGFR1 mutants
    Signaling by FGFR1 mutants0.67
    Signaling by FGFR1 fusion mutants0.63
    Signaling by FGFR mutants0.67
    2Signaling by FGFR
    Signaling by FGFR in disease0.91
    3VEGF Signaling Pathway
    VEGF Signaling Pathway0.34
    4Disease
    Disease

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    5        Reactome Pathways for FGFR1OP2
        Signaling by FGFR mutants
    Signaling by FGFR1 fusion mutants
    Signaling by FGFR in disease
    Signaling by FGFR1 mutants
    Disease

    1 PharmGKB Pathway for FGFR1OP2
        VEGF Signaling Pathway


    FGFR1OP2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FGFR1OP2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 20)

    5/21 Interacting proteins for FGFR1OP2 (Q9NVK53 ENSP000002293954) via UniProtKB, MINT, STRING, and/or I2D (see all 21)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    STK24Q9Y6E03, ENSP000003657304I2D: score=2 STRING: ENSP00000365730
    TRAF3IP3Q9Y2283, ENSP000000103384I2D: score=2 STRING: ENSP00000010338
    ZRANB1Q9UGI03, ENSP000003526764I2D: score=2 STRING: ENSP00000352676
    PPP2R1AP301533, ENSP000003248044I2D: score=1 STRING: ENSP00000324804
    STRNO438153, ENSP000002639184I2D: score=1 STRING: ENSP00000263918
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0009611response to wounding ----
    GO:0042060wound healing IEA--

    FGFR1OP2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FGFR1OP2 (FGOP2)

    Search CenterWatch for drugs/clinical trials and news about FGFR1OP2 / FGOP2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for FGFR1OP2 gene (3 alternative transcripts): 
    NM_001171887.1  NM_001171888.1  NM_015633.2  

    Unigene Cluster for FGFR1OP2:

    FGFR1 oncogene partner 2
    Hs.591162  [show with all ESTs]
    Unigene Representative Sequence: NM_015633
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000229395(uc001rhm.3 uc001rhn.3) ENST00000544111 ENST00000395941
    ENST00000546072(uc001rhl.3) ENST00000327214 ENST00000538172
    miRNA
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    8/23 QIAGEN miScript miRNA Assays for microRNAs that regulate FGFR1OP2 (see all 23):
    hsa-miR-495 hsa-miR-520d-5p hsa-miR-1297 hsa-miR-1244 hsa-miR-7-1* hsa-miR-558 hsa-miR-129-3p hsa-miR-129*
    SwitchGear 3'UTR luciferase reporter plasmidFGFR1OP2 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AF086411.1 AF161472.1 AK001534.1 AK094888.1 AL117545.1 AL117608.1 AY506561.1 BC032143.2 

    9 DOTS entries:

    DT.100646168  DT.210166  DT.100042064  DT.100751357  DT.442919  DT.95200942  DT.40118670  DT.95087970 
    DT.95088329 

    24/200 AceView cDNA sequences (see all 200):

    BM468103 BC032143 BM715091 BX507394 AF086411 BU739995 AA730013 AA262972 
    W74643 BM782815 BM768371 Z99418 BI829470 CB158376 BQ694324 AW571785 
    BP342418 BG258805 AL699273 BE894371 AK001534 NM_015633 BM972617 BU787452 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for FGFR1OP2 (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b · 8c
    SP1:                                      -           -     -                           
    SP2:              -                       -     -     -     -                           
    SP3:              -                       -           -     -                           
    SP4:              -                       -                                             
    SP5:              -                                                                     


    ECgene alternative splicing isoforms for FGFR1OP2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FGFR1OP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTAAAGACA
    FGFR1OP2 Expression
    About this image


    See FGFR1OP2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FGFR1OP2

    SOURCE GeneReport for Unigene cluster: Hs.591162

    UniProtKB/Swiss-Prot: FGOP2_HUMAN, Q9NVK5
    Tissue specificity: Expressed in bone marrow, spleen and thymus

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for FGFR1OP2 gene from 6/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fgfr1op21 , 5 FGFR1 oncogene partner 21, 5 89.06(n)1
    98.81(a)1
      6 (77.70 cM)5
    675291  NM_026218.21  NP_080494.11 
     1465772035 
    chicken
    (Gallus gallus)
    Aves FGFR1OP21 FGFR1 oncogene partner 2 82.02(n)
    93.95(a)
      418214  NM_001007855.1  NP_001007856.1 
    lizard
    (Anolis carolinensis)
    Reptilia FGFR1OP26
    Uncharacterized protein
    81(a)
    1 ↔ 1
    5(91093306-91099956)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC529632 hypothetical protein MGC52963 74(n)    BC041504.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufj17h042 wufj17h04 76.31(n)   335511  BC053266.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG101581 CG10158 47.67(n)
    34.08(a)
      33971  NM_135240.3  NP_609084.1 


    ENSEMBL Gene Tree for FGFR1OP2 (if available)
    TreeFam Gene Tree for FGFR1OP2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FGFR1OP2 gene
    SIKE12  
    1 SIMAP similar gene for FGFR1OP2 using alignment to 2 protein entries:     FGOP2_HUMAN (see all proteins):
    SIKE1

    FGFR1OP2 for paralogs           About GeneDecksing


    3 Pseudogenes.org Pseudogenes for FGFR1OP2
    PGOHUM00000239609 PGOHUM00000239768 PGOHUM00000248548


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/542 SNPs in FGFR1OP2 are shown (see all 542)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs730846211,2
    C,F--27093421(+) TGCGTT/ACTTTC 3 -- int11Minor allele frequency- A:0.01WA 118
    rs1482050701,2
    --27093536(+) GACACA/GTACCT 3 -- int10--------
    rs8408691,2
    C,F,O,A,H--27093585(+) AGACAC/GATCTG 3 -- int129Minor allele frequency- G:0.16MN NA NS EA WA CSA 2174
    rs749783721,2
    F--27093625(+) GTAGAT/AGTAGT 3 -- int11Minor allele frequency- A:0.02EA 120
    rs1418500931,2
    --27093632(+) TAGTGG/TTAGGA 3 -- int10--------
    rs1996846901,2
    --27093765(+) TGAAA-/TTTTTT 3 -- int10--------
    rs1904061261,2
    --27093861(+) AATTTG/TTCTTA 3 -- int10--------
    rs1462816221,2
    C--27094135(+) GCACTA/GTAAAA 3 -- int10--------
    rs118304591,2
    H--27094390(+) CACTGT/CGTTTC 3 -- int14Minor allele frequency- C:0.00NS EA 420
    rs1380098641,2
    --27094487(+) TTTAAA/GTGTAG 3 -- int10--------

    HapMap Linkage Disequilibrium report for FGFR1OP2 (27091305 - 27119583 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for FGFR1OP2:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv898935CNV Loss21882294
    nsv898938CNV Loss21882294
    dgv1397n71CNV Loss21882294

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 608858    OMIM disorders: --

    UniProtKB/Swiss-Prot: FGOP2_HUMAN, Q9NVK5
  • Note=A chromosomal aberration involving FGFR1OP2 may be a cause of stem cell myeloproliferative disorder
    (MPD). Insertion ins(12;8)(p11;p11p22) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and
    T-cell or B-cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion protein
    FGFR1OP2-FGFR1 may exhibit constitutive kinase activity and be responsible for the transforming activity

  • 11 diseases for FGFR1OP2:    About MalaCards
    cerebral cavernous malformations 3    cavernous malformation    cerebral cavernous malformation    lymphoblastic lymphoma
    stem cell leukemia    acute myeloid leukemia    eosinophilia    cerebritis
    t-cell leukemia    myeloid leukemia    leukemia


    FGFR1OP2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): FGFR1OP2
    Human Genome Epidemiology (HuGE) Navigator: FGFR1OP2 (2 documents)

    Export disorders for FGFR1OP2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FGFR1OP2 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with FGFR1OP2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of a novel gene, FGFR1OP2, fused to FGFR1 in 8p11 myeloproliferative syndrome. (PubMed id 15034873)1, 2, 3, 9 Grand E.K.... Cross N.C.P. (2004)
    2. Phosphotyrosine profiling identifies the KG-1 cell line as a model for the study of FGFR1 fusions in acute myeloid leukemia. (PubMed id 16946300)1, 2, 9 Gu T.-L....Polakiewicz R.D. (2006)
    3. A large-scale candidate gene association study of age at menarche and age at natural menopause. (PubMed id 20734064)1, 4 He C....Hunter D.J. (2010)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (2000)
    6. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    8. Sp1 phosphorylation by cyclin-dependent kinase 1/cycli n B1 represses its DNA-binding activity during mitosis in cancer cells. (PubMed id 22266860)1 Chuang J.Y....Hung J.J. (2012)
    9. Association between FGFR1OP2/wit3.0 polymorphisms and residual ridge resorption of mandible in Korean population. (PubMed id 22880093)1 Kim J.H....Lee J. (2012)
    10. A genetic association study of single nucleotide poly morphisms in FGFR1OP2/wit3.0 and long-term atrophy of edentulous mandible. (PubMed id 21283824)1 Suwanwela J....Nishimura I. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26127 HGNC: 23098 AceView: FGFR1OP2 Ensembl:ENSG00000111790 euGenes: HUgn26127
    ECgene: FGFR1OP2 H-InvDB: FGFR1OP2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FGFR1OP2 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for FGFR1OP2 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for FGFR1OP2 gene:
    Search GeneIP for patents involving FGFR1OP2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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