Aliases for FGFR1OP Gene
Aliases for FGFR1OP Gene
External Ids for FGFR1OP Gene
- HGNC: 17012
- Entrez Gene: 11116
- Ensembl: ENSG00000213066
- OMIM: 605392
- UniProtKB: O95684
Previous GeneCards Identifiers for FGFR1OP Gene
- GC06P167246
- GC06P167322
- GC06P167384
- GC06P167332
- GC06P167412
- GC06P164887
Summaries for FGFR1OP Gene
-
This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq, Jul 2013]
GeneCards Summary for FGFR1OP Gene
FGFR1OP (FGFR1 Oncogene Partner) is a Protein Coding gene. Diseases associated with FGFR1OP include Graves' Disease and Crohn's Disease. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and FGFR1 mutant receptor activation. GO annotations related to this gene include protein homodimerization activity and protein kinase binding.
UniProtKB/Swiss-Prot for FGFR1OP Gene
-
Required for anchoring microtubules to the centrosomes.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FGFR1OP Gene
Genomics for FGFR1OP Gene
Regulatory Elements for FGFR1OP Gene
Enhancers for FGFR1OP Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FGFR1OP on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for FGFR1OP Gene
- Chromosome:
- 6
- Start:
- 166,999,182 bp from pter
- End:
- 167,052,713 bp from pter
- Size:
- 53,532 bases
- Orientation:
- Plus strand
Genomic View for FGFR1OP Gene
Genes around FGFR1OP on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6q27 by Ensembl
- 6q27 by Entrez Gene
- 6q27 by HGNC
FGFR1OP Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FGFR1OP Gene
Proteins for FGFR1OP Gene
-
Protein details for FGFR1OP Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O95684-FR1OP_HUMAN
- Recommended name:
- FGFR1 oncogene partner
- Protein Accession:
- O95684
- A8K1D1
- B2R705
- Q49AI0
- Q5R3F6
- Q96EW1
Protein attributes for FGFR1OP Gene
- Size:
- 399 amino acids
- Molecular mass:
- 43065 Da
- Quaternary structure:
-
- Homodimer. Part of a ternary complex that contains CEP350, FGFR1OP and MAPRE1. Interacts directly with CEP350 and MAPRE1.
Protein Expression for FGFR1OP Gene
Post-translational modifications for FGFR1OP Gene
Other Protein References for FGFR1OP Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for FGFR1OP
- Invitrogen Antibodies for FGFR1OP
- antibodies-online Antibodies for FGFR1OP: See all 77
- GeneTex FGFR1OP antibody for FGFR1OP
-
Santa Cruz Biotechnology (SCBT) Antibodies for FGFR1OP
Protein Products
-
OriGene Purified Proteins for FGFR1OP
- Search Origene for MassSpec and Protein Over-expression Lysates for FGFR1OP
- Origene Custom Protein Services for FGFR1OP
- Sino Biological Cell Lysates for FGFR1OP
- Sino Biological Recombinant Proteins for FGFR1OP
- ProSpec Recombinant Proteins for FGFR1OP
- antibodies-online Proteins for FGFR1OP: See all 10
- Search antibodies-online for peptides
- Search GeneTex for Proteins for FGFR1OP
Assay Products
- antibodies-online Kits for FGFR1OP: See all 7
No data available for DME Specific Peptides for FGFR1OP Gene
Domains & Families for FGFR1OP Gene
Protein Domains for FGFR1OP Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for FGFR1OP Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O95684- Family:
-
- Belongs to the FGFR1OP family.
No data available for Gene Families for FGFR1OP Gene
Function for FGFR1OP Gene
Molecular function for FGFR1OP Gene
- UniProtKB/Swiss-Prot Function:
- Required for anchoring microtubules to the centrosomes.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004713 | protein tyrosine kinase activity | TAS | -- |
| GO:0005515 | protein binding | IPI | 17888034 |
| GO:0019901 | protein kinase binding | IPI | 17888034 |
| GO:0030292 | protein tyrosine kinase inhibitor activity | IDA | 17888034 |
| GO:0042803 | protein homodimerization activity | IDA | 16690081 |
Phenotypes for FGFR1OP Gene
- MGI mutant phenotypes for FGFR1OP:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for FGFR1OP:
Animal Models for FGFR1OP Gene
- MGI Knock Outs for FGFR1OP:
-
- Fgfr1op tm1b(EUCOMM)Hmgu
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for FGFR1OP gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FGFR1OP gene
- Search ViGene Biosciences for FGFR1OP
CRISPR Products
-
OriGene CRISPR knockouts for FGFR1OP
-
Santa Cruz Biotechnology (SCBT) CRISPR for FGFR1OP
- GenScript: Design CRISPR guide RNA sequences for FGFR1OP
miRNA for FGFR1OP Gene
- miRTarBase miRNAs that target FGFR1OP
-
- hsa-mir-192-5p (MIRT026178)
- hsa-mir-340-5p (MIRT557856)
- hsa-mir-5590-3p (MIRT557857)
- hsa-mir-142-5p (MIRT557858)
- hsa-mir-32-3p (MIRT557859)
- hsa-mir-651-3p (MIRT557860)
- hsa-mir-583 (MIRT557861)
- hsa-mir-527 (MIRT557862)
- hsa-mir-518a-5p (MIRT557863)
- hsa-mir-548aw (MIRT567523)
- hsa-mir-19b-3p (MIRT567524)
- hsa-mir-19a-3p (MIRT567525)
- hsa-mir-891b (MIRT567526)
- hsa-mir-1468-3p (MIRT567527)
- hsa-mir-548x-5p (MIRT567528)
- hsa-mir-548g-5p (MIRT567529)
- hsa-mir-548f-5p (MIRT567530)
- hsa-mir-548aj-5p (MIRT567531)
- hsa-mir-454-3p (MIRT567532)
- hsa-mir-4295 (MIRT567533)
- hsa-mir-3666 (MIRT567534)
- hsa-mir-301b-3p (MIRT567535)
- hsa-mir-301a-3p (MIRT567536)
- hsa-mir-130b-3p (MIRT567537)
- hsa-mir-130a-3p (MIRT567538)
- hsa-mir-519c-3p (MIRT567539)
- hsa-mir-519b-3p (MIRT567540)
- hsa-mir-519a-3p (MIRT567541)
- hsa-mir-4796-3p (MIRT567542)
- hsa-mir-93-5p (MIRT567543)
- hsa-mir-526b-3p (MIRT567544)
- hsa-mir-519d-3p (MIRT567545)
- hsa-mir-20b-5p (MIRT567546)
- hsa-mir-20a-5p (MIRT567547)
- hsa-mir-17-5p (MIRT567548)
- hsa-mir-106b-5p (MIRT567549)
- hsa-mir-106a-5p (MIRT567550)
- hsa-mir-548ah-5p (MIRT567551)
- hsa-mir-3609 (MIRT567552)
- hsa-mir-203a-3p (MIRT567553)
- hsa-mir-8485 (MIRT610687)
- hsa-mir-451b (MIRT625989)
- hsa-mir-3942-3p (MIRT637275)
- hsa-mir-4696 (MIRT637276)
- hsa-mir-205-3p (MIRT637277)
- hsa-mir-6502-3p (MIRT637278)
- hsa-mir-6811-5p (MIRT646226)
- hsa-mir-6511b-5p (MIRT646227)
- hsa-mir-365b-5p (MIRT646228)
- hsa-mir-365a-5p (MIRT646229)
- hsa-mir-8052 (MIRT646230)
- hsa-mir-3199 (MIRT646231)
- hsa-mir-1288-3p (MIRT646232)
- hsa-mir-6778-3p (MIRT646233)
- hsa-mir-1205 (MIRT646234)
- hsa-mir-4740-3p (MIRT646235)
- hsa-mir-6715b-5p (MIRT646236)
- hsa-mir-4269 (MIRT646237)
- hsa-mir-509-5p (MIRT646238)
- hsa-mir-4418 (MIRT646239)
- hsa-mir-509-3-5p (MIRT646240)
- hsa-mir-6513-5p (MIRT663153)
- hsa-mir-887-5p (MIRT663154)
- hsa-mir-3913-5p (MIRT663155)
- hsa-mir-3122 (MIRT663156)
- hsa-mir-450a-1-3p (MIRT663157)
- hsa-mir-6780a-5p (MIRT663158)
- hsa-mir-6779-5p (MIRT663159)
- hsa-mir-3689c (MIRT663160)
- hsa-mir-3689b-3p (MIRT663161)
- hsa-mir-3689a-3p (MIRT663162)
- hsa-mir-30b-3p (MIRT663163)
- hsa-mir-1273h-5p (MIRT663164)
- hsa-mir-6788-5p (MIRT663165)
- hsa-mir-30c-2-3p (MIRT663166)
- hsa-mir-30c-1-3p (MIRT663167)
- hsa-mir-7977 (MIRT663168)
- hsa-mir-6781-5p (MIRT663169)
- hsa-mir-6877-5p (MIRT663170)
- hsa-mir-6799-5p (MIRT663171)
- hsa-mir-6883-5p (MIRT663172)
- hsa-mir-6785-5p (MIRT663173)
- hsa-mir-4728-5p (MIRT663174)
- hsa-mir-149-3p (MIRT663175)
- hsa-mir-7106-5p (MIRT663176)
- hsa-mir-5787 (MIRT663177)
- hsa-mir-4505 (MIRT663178)
- hsa-mir-6884-5p (MIRT663179)
- hsa-mir-485-5p (MIRT663180)
- hsa-mir-383-3p (MIRT663181)
- hsa-mir-4279 (MIRT679965)
- hsa-mir-1976 (MIRT679966)
- hsa-mir-3653-5p (MIRT679967)
- hsa-mir-6747-3p (MIRT679968)
- hsa-mir-6727-3p (MIRT679969)
- hsa-mir-4722-3p (MIRT679970)
- hsa-mir-3670 (MIRT703560)
- hsa-mir-6868-3p (MIRT722548)
- hsa-mir-6881-3p (MIRT722549)
- hsa-mir-6780a-3p (MIRT722550)
- hsa-mir-7111-3p (MIRT722551)
- hsa-mir-130b-5p (MIRT722552)
- hsa-mir-3667-3p (MIRT722553)
- hsa-mir-6734-3p (MIRT722554)
- hsa-mir-877-3p (MIRT722555)
miRNA Products
- Search ViGene Biosciences for FGFR1OP
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FGFR1OP
- Browse OriGene Inhibitory RNA Products For FGFR1OP
-
ViGene Biosciences ready-to-package AAV shRNAs for FGFR1OP gene
Clone Products
- Sino Biological Human cDNA Clone for FGFR1OP
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for FGFR1OP gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FGFR1OP gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FGFR1OP gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for FGFR1OP Gene
Localization for FGFR1OP Gene
Subcellular locations from UniProtKB/Swiss-Prot for FGFR1OP Gene
- Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Associated with gamma-tubulin.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| nucleus | 5 |
| cytosol | 5 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IDA | 17888034 |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005813 | centrosome | IDA | 16690081 |
| GO:0005815 | microtubule organizing center | IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
Pathways & Interactions for FGFR1OP Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Regulation of PLK1 Activity at G2/M Transition |
.49
|
|
| 2 | FGFR1 mutant receptor activation | ||
| 3 | Cell Cycle, Mitotic |
.83
|
|
| 4 | Organelle biogenesis and maintenance |
.56
|
|
| 5 | HIV Life Cycle |
.45
|
|
Pathways by source for FGFR1OP Gene
19 Reactome pathways for FGFR1OP Gene
1 PharmGKB pathway for FGFR1OP Gene
Interacting Proteins for FGFR1OP Gene
Selected Interacting proteins:
ENSP00000355812
O95684-FR1OP_HUMAN
for FGFR1OP Gene via
STRING
MINT
UniProtKB
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000086 | G2/M transition of mitotic cell cycle | TAS | -- |
| GO:0006469 | negative regulation of protein kinase activity | IDA | 17888034 |
| GO:0008284 | positive regulation of cell proliferation | IDA | 17888034 |
| GO:0018108 | peptidyl-tyrosine phosphorylation | IEA | -- |
| GO:0030307 | positive regulation of cell growth | IDA | 17888034 |
Transcripts for FGFR1OP Gene
mRNA/cDNA for FGFR1OP Gene
- (3) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (60) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FGFR1OP Gene
CRISPR Products
-
OriGene CRISPR knockouts for FGFR1OP
-
Santa Cruz Biotechnology (SCBT) CRISPR for FGFR1OP
- GenScript: Design CRISPR guide RNA sequences for FGFR1OP
miRNA Products
- Search ViGene Biosciences for FGFR1OP
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FGFR1OP
- Browse OriGene Inhibitory RNA Products For FGFR1OP
-
ViGene Biosciences ready-to-package AAV shRNAs for FGFR1OP gene
Clone Products
- Sino Biological Human cDNA Clone for FGFR1OP
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
Expression for FGFR1OP Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Testis (Reproductive System)
- Leydig Cells Testis Interstitium
- Testis Interstitium
This gene is overexpressed in Testis (45.0) and Blymphocyte (7.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for FGFR1OP Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of FGFR1OP Gene:
FGFR1OPSOURCE GeneReport for Unigene cluster for FGFR1OP Gene:
Hs.487175mRNA Expression by UniProt/SwissProt for FGFR1OP Gene:
O95684-FR1OP_HUMAN
Tissue specificity:
Ubiquitous. Highly expressed in heart, liver, muscle, kidney, intestine, colon, adrenal gland, prostate, testis, and pancreas.
Evidence on tissue expression from TISSUES for FGFR1OP Gene
- Nervous system(4.4)
- Liver(4.3)
- Blood(4.2)
- Muscle(4.2)
Primer Products
-
OriGene qPCR primer pairs for FGFR1OP
-
OriGene qPCR primer pairs and template standards for FGFR1OP
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for FGFR1OP Gene
Orthologs for FGFR1OP Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FGFR1OP 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | FGFR1OP 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | LOC683722 34 |
|
||
| dog (Canis familiaris) |
Mammalia | FGFR1OP 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Fgfr1op 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
OneToMany | |
| -- 35 |
|
OneToMany | |||
| platypus (Ornithorhynchus anatinus) |
Mammalia | FGFR1OP 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | FGFR1OP 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | FGFR1OP 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | fgfr1op 34 |
|
||
| Str.6447 34 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.15774 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | fgfr1op 34 35 |
|
||
| Dr.3646 34 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.846 34 |
|
- Species where no ortholog for FGFR1OP was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for FGFR1OP Gene
No data available for Paralogs for FGFR1OP Gene
Variants for FGFR1OP Gene
| SNP ID | Clin | Chr 06 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000032773 | -- | 167,037,680(+) | AGAGG(A/G)TATGT | intron-variant | |
| rs1000046212 | -- | 166,999,493(+) | AACAG(A/C)GGGGT | upstream-variant-2KB, reference, missense | |
| rs1000111003 | -- | 167,010,766(+) | TATTT(A/G)TGTTT | intron-variant | |
| rs1000210776 | -- | 167,028,500(+) | GTTTT(A/G)CAACA | intron-variant | |
| rs1000221327 | -- | 167,020,714(+) | GACCA(A/G)CGTGG | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2182370 | CNV | deletion | 18987734 |
| esv2733213 | CNV | deletion | 23290073 |
| esv2733214 | CNV | deletion | 23290073 |
| esv2733215 | CNV | deletion | 23290073 |
| esv2733216 | CNV | deletion | 23290073 |
| esv2752099 | CNV | gain | 17911159 |
| esv3327167 | CNV | insertion | 20981092 |
| esv3355616 | CNV | duplication | 20981092 |
| nsv1124147 | CNV | deletion | 24896259 |
| nsv464140 | CNV | loss | 19166990 |
| nsv519550 | CNV | loss | 19592680 |
| nsv605260 | CNV | gain | 21841781 |
Residual Variation Intolerance Score:
66.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.83;
73.90% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FGFR1OP Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- FGFR1OP
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FGFR1OP Gene
Disorders for FGFR1OP Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| graves' disease |
|
|
| crohn's disease |
|
|
| 8p11 myeloproliferative syndrome |
|
|
| bone marrow cancer |
|
Search FGFR1OP in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
FR1OP_HUMAN- Note=A chromosomal aberration involving FGFR1OP may be a cause of stem cell myeloproliferative disorder (MPD). Translocation t(6;8)(q27;p11) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion proteins FGFR1OP-FGFR1 or FGFR1-FGFR1OP may exhibit constitutive kinase activity and be responsible for the transforming activity (PubMed:9949182). {ECO:0000269 PubMed:9949182}.
Relevant External Links for FGFR1OP
No data available for Genatlas for FGFR1OP Gene
Publications for FGFR1OP Gene
- The t(6;8)(q27;p11) translocation in a stem cell myeloproliferative disorder fuses a novel gene, FOP, to fibroblast growth factor receptor 1. (PMID: 9949182) Popovici C. … Pebusque M.-J. (Blood 1999) 2 3 4 22 64
- A complex of two centrosomal proteins, CAP350 and FOP, cooperates with EB1 in microtubule anchoring. (PMID: 16314388) Yan X. … Nigg E.A. (Mol. Biol. Cell 2006) 3 4 22 64
- Structure of the N-terminal domain of the FOP (FGFR1OP) protein and implications for its dimerization and centrosomal localization. (PMID: 16690081) Mikolajka A. … Holak T.A. (J. Mol. Biol. 2006) 3 4 22 64
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
- Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC. (PMID: 20526339) Quan C. … Zhang X.J. (Nat. Genet. 2010) 3 46 64
Products for FGFR1OP Gene
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- Custom Antibody Services
- Browse OriGene ELISA Kits
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- OriGene Purified Proteins for FGFR1OP
- Search Origene for MassSpec and Protein Over-expression Lysates for FGFR1OP
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- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for FGFR1OP
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- OriGene qPCR primer pairs and template standards for FGFR1OP
- OriGene qPCR primer pairs for FGFR1OP
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- GenScript: Design CRISPR guide RNA sequences for FGFR1OP
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- CloneReady with Over 120,000 Genes
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- Gene Mutant Library, Variants up to 10^11
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- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for FGFR1OP
- Novus Biologicals proteins and lysates for FGFR1OP
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ProSpec Recombinant Proteins for FGFR1OP
- antibodies-online Antibodies for FGFR1OP: See all 77
- antibodies-online Kits for FGFR1OP: See all 7
- antibodies-online Proteins for FGFR1OP: See all 10
- Search antibodies-online for peptides
- GeneTex FGFR1OP antibody for FGFR1OP
- Search GeneTex for Proteins for FGFR1OP
- ViGene Biosciences adenoviral particle packaged cDNA for FGFR1OP gene
- ViGene Biosciences lentiviral particle packaged cDNA for FGFR1OP gene
- ViGene Biosciences ready-to-package AAV shRNAs for FGFR1OP gene
- Search ViGene Biosciences for FGFR1OP
- Santa Cruz Biotechnology (SCBT) Antibodies for FGFR1OP
- Search Santa Cruz Biotechnology (SCBT) for FGFR1OP siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for FGFR1OP
- Cyagen custom Knockout/knockin (KOKI) mouse models for FGFR1OP
- VectorBuilder custom plasmid, inducible vectors for FGFR1OP
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FGFR1OP
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FGFR1OP Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer