V3 here soon-try beta now
Gene Search (GeneCards Home) | GeneCards Guide | User Feedback | Terms of Use | Notice about third-party sites
 

FGF8 Gene

protein-coding   GIFtS: 65

GC10M103519
fibroblast growth factor 8 (androgen-induced)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    

Aliases &
Descriptions
for FGF8

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
AIGF 1, 2, 3
FGF-8 3
HBGF-8 2, 3
KAL6 2, 5
MGC149376 2
OTTHUMP00000020348 2
OTTHUMP00000020349 2
OTTHUMP00000020350 2
OTTHUMP00000020351 2
Descriptions
Androgen-induced growth factor 2, 3
Heparin-binding growth factor 8 3
fibroblast growth factor 8 2
fibroblast growth factor 8 (androgen-induced) 2
External Ids
HGNC: 36861
Entrez Gene: 22532
UniProtKB: P550753
Ensembl: ENSG000001078317
Search outside databases for aliases for FGF8 gene

Previous GC identifers: GC10M102423 GC10M102763 GC10M103661 GC10M103194

Summaries
for FGF8

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for FGF8:
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF
family members possess broad mitogenic and cell survival activities, and are involved in a variety
of biological processes, including embryonic development, cell growth, morphogenesis, tissue
repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and
anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to
increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes
and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an
embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain
and limb development, organogenesis, embryo gastrulation and left-right axis determination. The
alternative splicing of this gene results in four transcript variants. [provided by RefSeq]

UniProtKB/Swiss-Prot: FGF8_HUMAN, P55075
Function: Stimulates growth of the cells in an autocrine manner. Mediates hormonal action on the
growth of cancer cells

Gene Wiki entry for FGF8

Genomic Location
for FGF8

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the FGF8 gene  

Entrez Gene cytogenetic band: 10q24   Ensembl cytogenetic band:  10q24.32   HGNC cytogenetic band: 10q25-q26

FGF8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M103519:     (about GC identifiers)

Start:
 103,519,877 bp from pter
End:
 103,525,817 bp from pter
Size:
 5,941 bases
Orientation:
 minus strand
RefSeq DNA sequence:
NC_000010.9  NT_030059.12  

Proteins
for FGF8

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: FGF8_HUMAN, P55075 (See protein sequence)
Recommended Name: Fibroblast growth factor 8 precursor  
Size: 233 amino acids; 26525 Da
Subcellular location: Secreted
Developmental stage: In adults expression is restricted to the gonads
PDB structures from and Proteopedia :
2FDB (3D)    
Secondary accessions: Q14915 Q15766
Alternative splicing: 4 isoforms:  P55075-1   P55075-2   P55075-3   P55075-4   (Additional isoforms seem to exist)

REFSEQ proteins (4 alternative transcripts): 
NP_006110.1  NP_149353.1  NP_149354.1  NP_149355.1  


ENSEMBL proteins: 
ENSP00000321945 ENSP00000344306 ENSP00000340039 ENSP00000321797 


Human Recombinant Proteins 
Invitrogen human recombinant proteins for FGF8
Millipore Purified and/or Recombinant FGF8 Protein
Sigma-Aldrich Proteins and CompoZr ZFN for FGF8  
R&D Systems Recombinant & Natural Proteins for FGF8 (FGF-8)
Browse recombinant and purified proteins available from Enzo Life Sciences
Recombinant Proteins from Abcam (FGF8)
Browse Abnova for Human Recombinant Proteins
              OriGene Purified Recombinant Human Protein: FGF8 

1 Gene Ontology (GO) cellular component term (links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0005576 extracellular region IEA--
About this table

Antibodies for FGF8: 
Browse Antibodies Central at Invitrogen
Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Sigma-Aldrich Antibodies for FGF8
R&D Systems Antibodies for FGF8 (FGF-8)
Antibodies from Abcam (FGF8), each with their AbpromiseSM
Monoclonal and Polyclonal Antibodies from Abnova (FGF8)
Novus Biologicals Antibodies for FGF8

Assays for FGF8: 
Browse Invitrogen for biochemical assays
Browse Kits and Assays available from Millipore
Browse R&D Systems for biochemical assays
Browse biochemical assays available from Enzo Life Sciences

Protein Domains/
Families
for FGF8

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
1 InterPro domain/family:
 IPR002348 IL1_HBGF


   GeneDecks  FGF8 for the domains selected above  
About GeneDecksing

Graphical View of Domain Structure for InterPro Entry P55075

ProtoNet protein and cluster: P55075

1 Blocks protein family: IPB002348 IL1/HBGF family signature

UniProtKB/Swiss-Prot: FGF8_HUMAN, P55075
Similarity: Belongs to the heparin-binding growth factors family

Gene Function
for FGF8

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section
Inhib.
RNA:		Invitrogen RNAi Products for gene knock-down (FGF8)
Browse for Gene Knock-down Tools from Millipore
Abnova Chimera RNAi Products for Gene knock-down (FGF8)
               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4): NM_006119

              Applied Biosystems Silencer® siRNAs for FGF8

              Sigma-Aldrich siRNA and siRNA Panels for FGF8  
                     Sigma-Aldrich shRNA Panels and shRNA for FGF8  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Clones:Browse Clone Ranger at Invitrogen for clones
Browse Clones for the Expression of Recombinant Proteins Available from Millipore
               OriGene GFP tagged cDNA clones in CMV expression vector (see all 4): NM_006119
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 4): NM_006119
                                 untagged cDNA clones in CMV expression vector (see all 4): NM_006119 

Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
              OriGene genome-wide validated SYBR primer pairs: NM_033163

UniProtKB/Swiss-Prot: FGF8_HUMAN, P55075
Function: Stimulates growth of the cells in an autocrine manner. Mediates hormonal action on the
growth of cancer cells

Genatlas biochemistry entry for FGF8:
fibroblast growth factor 8,involved in the development of the central nervous
system,face,limbs,(key indicator of apical ectodermal ridge,AER) kidney in mouse,unlikely involved
in craniosynostosis/limb defect syndromes

15/22 MGI mutant phenotypes (inferred from 10 alleles) (MGI details for Fgf8) (see all 22 ):

behavior/neurologicalcellularcraniofacialdigestive/alimentary
embryogenesisendocrine/exocrine glandgrowth/sizehearing/vestibular/earhematopoietic system
homeostasis/metabolismimmune systemlethality-postnatallethality-prenatal/perinatallimbs/digits/tail

1 Gene Ontology (GO) molecular function term (links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0008083 growth factor activity NAS--
About this table

Pathways & Interactions
for FGF8

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

1 Invitrogen iPath™ Online BioAtlas - Pathway for FGF8 (Maps provided by GeneGo):
 FGF-family signaling

   GeneDecks  FGF8 for the pathways selected above  
About GeneDecksing

1 Millipore Pathway for FGF8
 Development FGF-family signaling

   GeneDecks  FGF8 for the pathways selected above  
About GeneDecksing

4 Sigma-Aldrich "Your Favorite Gene" Pathways for  FGF8  (Your Favorite Gene powered by Ingenuity) 
 FGF Signaling
 Clathrin-mediated Endocytosis
 Actin Cytoskeleton Signaling
 Bladder Cancer Signaling

   GeneDecks  FGF8 for the pathways selected above  
About GeneDecksing

4 Kegg Pathways  (Kegg details for FGF8):
 hsa04010 MAPK signaling pathway
 hsa04810 Regulation of actin cytoskeleton
 hsa05200 Pathways in cancer
 hsa05218 Melanoma

   GeneDecks  FGF8 for the pathways selected above  
About GeneDecksing
 Gene Network CentralTM Interacting Genes and Proteins Network for  FGF8 


5/123 Interacting proteins for FGF8 (ENSP000003217973) via UniProtKB, MINT, and/or STRING (see all 123 )
InteractantInteraction Details
GeneCardExternal ID(s)
FGFR1ENSP000003113373STRING (score=.999)
FGFR2ENSP000003330903STRING (score=.999)
FGFR3ENSP000003541703STRING (score=.999)
FGFR4ENSP000003664123STRING (score=.999)
FGF19ENSP000002943123STRING (score=.996)
About this table

5/6 Gene Ontology (GO) biological process terms (links to tree view) (see all 6 ):

GO IDQualified GO termEvidencePubMed IDs
GO:0007165 signal transduction NAS8700553
GO:0007275 multicellular organismal development TAS8661131
GO:0007369 gastrulation TAS8700553
GO:0008283 cell proliferation NAS--
GO:0008543 fibroblast growth factor receptor signaling pathway EXP17133345
About this table

Drugs & Compounds
for FGF8

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences
Sigma-Aldrich Small Molecules for FGF8:
Inhibitor

Browse Tocris compounds for FGF8
4 Novoseek chemical compound relationships for FGF8 gene
Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
tyrosine 25.98 9 16399079 (2), 11312556 (1), 17085092 (1), 15917474 (1)
heparan sulfate 10.39 2 17493930 (1), 12077148 (1)
forskolin 0.00 3 15193767 (2), 15245752 (1)
zinc 0.00 2 9004130 (1)
About this table


Transcripts
for FGF8

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section
Inhib.
RNA:		Invitrogen RNAi Products for gene knock-down (FGF8)
Browse for Gene Knock-down Tools from Millipore
Abnova Chimera RNAi Products for Gene knock-down (FGF8)
               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4): NM_006119

              Sigma-Aldrich siRNA and siRNA Panels for FGF8  
                     Sigma-Aldrich shRNA Panels and shRNA for FGF8  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Applied Biosystems Silencer® siRNAs: 

NM_006119  NM_033163  NM_033164  NM_033165  

REFSEQ mRNAs for FGF8 gene (4 alternative transcripts): 

NM_006119.3   NM_033163.2   NM_033164.2   NM_033165.2   

Applied Biosystems TaqMan ® Gene Expression Assays: 

NM_006119  NM_033163  NM_033164  NM_033165  

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 4): NM_006119
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 4): NM_006119
                                 untagged cDNA clones in CMV expression vector (see all 4): NM_006119 

Additional cDNA sequence: 

AB014615.1 BC069106.1 BC128235.1 BC128236.1 U36223.1 U46211.1 U46212.1 U46213.1 
U46214.1 U56978.1 

4 DOTS entries:

DT.456212  DT.92415929  DT.100020014  DT.92415927 

14 AceView cDNA sequences:

BX281460 U46213 U46211 U46212 NM_033164 NM_006119 NM_033163 NM_033165 
BC069106 AB014615 U56978 U36223 BG115475 U46214 

highest scoring ESTs for FGF8:

AB014615 BC069106 U36223 U46211 U46212 U46213 U56978 BG115475 BX281460 NM_006119 

Unigene Cluster for FGF8:

Fibroblast growth factor 8 (androgen-induced)
Hs.57710  [show with all ESTs]
Unigene Representative Sequence: NM_033163


GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for FGF8

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b
SP1:                                                
SP2:                    -                           
SP3:        -     -                                 
SP4:              -     -                           
SP5:              -                                 

About this scheme

ECgene alternative splicing isoforms for FGF8

4 Ensembl transcripts including schematic representations:
ENST00000347978  ENST00000346714  ENST00000344255  ENST00000320185  

Expression
for FGF8

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

FGF8 expression in normal and diseased human tissues

 Applied Biosystems TaqMan ® Gene Expression Assays for FGF8

1 / 2 / 3

4 probe-sets matching FGF8 gene


Affymetrix
probe-set		 Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank

1525_s_at2, 3 U95-A 1 1.00 1.00 1.00 1.00 U47011 0.20 1.00 0.72 1

1526_i_at2, 3 U95-A 1 1.00 1.00 0.50 0.51 U47011 0.20 1.00 0.72 1

208449_s_at2, 3 U133-A 1 1.00 1.00 -- -- NM_006119 0.60 1.00 0.82 1

208449_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
About this table
Data from (Publications) and GNF BioGPS
    About these images
About these images

CGAP SAGE TAG: AAGCGGCTGC

SOURCE GeneReport for Unigene cluster: Hs.57710

Expression variation in blood from EXPOLDB for FGF8

Orthologs
for FGF8

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section
Orthologs for FGF8 gene from 5/9 species (see all 9 )
Organism Gene Locus Description Human
Similarity		 NCBI accessions
dog
(Canis familiaris)		 FGF81   -- fibroblast growth factor 8 (androgen-induced) 92.03(n)
94.26(a)		 403868  XM_846690.1  XP_851783.1 
chimpanzee
(Pan troglodytes)		 FGF81   -- fibroblast growth factor 8 (androgen-induced) 91.46(n)
88.43(a)		 745174  XM_001170284.1  XP_001170284.1 
cow
(Bos taurus)		 FGF81   -- fibroblast growth factor 8 (androgen-induced) 93.81(n)
99.05(a)		 326284  XM_612205.3  XP_612205.2 
rat
(Rattus norvegicus)		 Fgf81   -- fibroblast growth factor 8 95.42(n)
100(a)		 29349  NM_133286.1  NP_579820.1 
mouse
(Mus musculus)		 Fgf81, 5 19 (45.00 cM)5
 fibroblast growth factor 81, 5 87.7(n)1
90.57(a)1		 141791  NM_010205.11  NP_034335.11 
 AK1319805  BC0487345  (see all 10)
About this table        Species with no ortholog for FGF8

ENSEMBL Gene Tree for FGF8

Paralogs
for FGF8

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section

Paralogs for FGF8 gene
FGF172  FGF182  

SNPs/Variants
for FGF8

(According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section


10/39 NCBI SNPs in FGF8 are shown (see all 39 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 42)
ABGenomic DataTranscription DataAllele Frequencies
SNP IDValidChr 10 posSequenceRecsAA
Chg		TypeMoreRecsAllele
freq		PopTotal
sample		More
------------
rs13488701,2
A,C,F103527535(-) CACTTC/TCCCCA 4 -- ng315Minor allele frequency- G:0.06EA NA NS 332
rs32182251,2
C,F,H103527398(-) GAGCCC/TACTGA 4 -- ng315Minor allele frequency- T:0.01NS EU EA WA 596
--
rs27354301,2
C,F103525926(-) ctcccC/Agccct 4 -- ng31 tfbs31Minor allele frequency- A:0.04NS 166
--
rs32182391,2
F103519952(-) CCCTGG/CGTTCC 4 -- ut31 ese31Minor allele frequency- C:0.01NS 180
--
rs32182241,2
F103527672(-) GAGAC-/CAGTGC 4 -- ng311Minor allele frequency- C:0.04NS 166
rs32182321,2
C,F,H103523318(-) GGTTTG/AAAAAT 4 -- int111Minor allele frequency- A:0.02NS EU EA WA 1072
rs32182291,2
F,H103524070(-) AAAGGA/GGGTTG 4 -- int1 trp35Minor allele frequency- G:0.01NS EU EA WA 598
--
rs32182381,2
F103520428(-) GGGCCG/ACTCGC 4 -- int11Minor allele frequency- A:0.04NS 178
--
rs32182361,2
F103521072(-) CCTCAC/TGATTG 4 -- int11Minor allele frequency- T:0.02NS 180
--
rs32182341,2
F103521191(-) AGGCAG/AGTGGG 4 -- int11Minor allele frequency- A:0.01NS 180
About this table

HapMap Linkage Disequilibrium images for FGF8 (up to first 250kb)

Disorders & Mutations
for FGF8

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

 OMIM: 600483   disorders: 612702  

UniProtKB/Swiss-Prot: FGF8_HUMAN, P55075

  • Defects in FGF8 are the cause of Kallmann syndrome type 6 (KAL6) [MIM:612702]. Kallmann
    syndrome is a disorder that associates hypogonadotropic hypogonadism and anosmia. Anosmia or
    hyposmia is related to the absence or hypoplasia of the olfactory bulbs and tracts. Hypogonadism
    is due to deficiency in gonadotropin-releasing hormone and probably results from a failure of
    embryonic migration of gonadotropin-releasing hormone-synthesizing neurons. In some patients other
    developmental anomalies can be present, which include renal agenesis, cleft lip and/or palate,
    selective tooth agenesis, and bimanual synkinesis. In some cases anosmia may be absent or
    inconspicuous
  • Defects in FGF8 are a cause of idiopathic hypogonadotropic hypogonadism (IHH)
    [MIM:146110]. IHH is defined as a deficiency of the pituitary secretion of follicle-stimulating
    hormone and luteinizing hormone, which results in the impairment of pubertal maturation and of
    reproductive function

    • 10/23 Novoseek disease relationships for FGF8 gene (see all 23 )

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    caronte 83.36 1 10882519 (1)
    pfeiffer syndrome 57.81 2 9332670 (1)
    prostate cancer 41.46 69 11406643 (8), 18386787 (7), 10348350 (4), 10629559 (4) (see all 22)
    teratocarcinoma 41.08 3 11764380 (1), 9366493 (1), 12820388 (1)
    mammary tumor 38.71 13 9784427 (2), 16252261 (2), 8738604 (1), 15897591 (1) (see all 6)
    holoprosencephaly 37.16 1 18173302 (1)
    craniosynostosis 34.50 5 9332670 (2), 8595889 (1)
    parkinson disease 32.85 3 17640353 (1), 11532426 (1)
    prostatic intraepithelial neoplasia 30.78 1 11406643 (1)
    hypospadias 30.21 6 17264867 (6)
    About this table

    Human Gene Mutation Database: FGF8
    Human Genome Epidemiology Navigator: FGF8 (1 document)

    Medical News
    for FGF8

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for FGF8

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/241 PubMed articles for FGF8 gene (see all 241 ):

    Search for FGF8

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing FGF8

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 2253 HGNC: 3686 AceView: FGF8 Ensembl:ENSG00000107831 euGenes: HUgn2253
    ECgene: FGF8 H-InvDB: FGF8

    Other Databases showing FGF8

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing FGF8

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    ATLAS Chromosomes in Cancer entry for FGF8 Genetics and Cytogenetics in Oncology and Haematology
    NIEHS-SNPshttp://egp.gs.washington.edu/data/fgf8/

    Licensable Technologies
    for FGF8

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for FGF8

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for FGF8:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for FGF8-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for FGF8 Antibodies for FGF8
     Explore super-pooled esiRNAs Proteins for FGF8
     Lentivirus-delivered shRNAs for FGF8 Small molecules for FGF8
     "Your Favorite Gene" Pathwaysfeedback


      
     Antibodies   Primer Pairs  
     Cell Culture Products   ELISAs  
     Flow Cytometry Kits   Protease Activity Assays & Reagents  
     Cell Selection/Detection Kits & Reagents   ELISA/Assay Development Kits & Reagents  
     Multiplex/Array Assay Kits & Reagents   ELISpot Kits & Development Modules  
     Recombinant & Natural Proteins  

     Search for Recombinant Proteins
     Antibodies (FGF8)
     Chimera RNAi (FGF8)
     Custom Service for Mouse Mab
     Custom Service for Rabbit Pab from Full-length Protein
      
     Search for Antibodies & Assays

     Recombinant Proteins
    (FGF8)
     Antibodies (FGF8)
     Tagged/untagged cDNA clones
     Validated SYBR primer pairs
     Purified proteins from HEK293T cells
     Western blot validated antibodies
     shRNA in GFP-retroviral vector
     Search Tocris compounds for FGF8




     Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
     Antibodies for FGF8

    GeneCards Homepage    -    Last full update: 1 Jul 2009        Incremental update: 13 Oct 2009

    Random Gene From GIFtS : about GIFtS

    Gene Index:   3   5   A   B   C   D   E   F   G   H   I   J   K   L   M   N   O   P   Q   R   S   T   U   V   W   X   Y   Z

    Developed at the Crown Human Genome Center & Weizmann Institute of Science



    The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
    FGF8 Gene at Home site.
    Version 2.41.1
    server5.xennexinc.com