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FGF3 Gene

protein-coding GIFtS: 57

GC11M069333

fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: INT2)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
FGF-3 ^³
HBGF-3 ^¹, ², ³
INT2 ^², ³, ⁵

Descriptions
Fibroblast growth factor 3 ^², ³
Heparin-binding growth factor 3 ^³
INT-2 proto-oncogene protein ^²
V-INT2 murine mammary tumor virus integration site oncogene homolog ^²
fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog) ^²
murine mammary tumor virus integration site 2, mouse ^²
oncogene INT2 ^²

External Ids
HGNC: 3681¹
Entrez Gene: 2248²
UniProtKB: P11487³
Ensembl: ENSG00000186895⁷

Search outside databases for aliases for FGF3 gene

Previous GC identifers: GC11U990037 GC11M069397

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for FGF3:

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF

family members possess broad mitogenic and cell survival activities and are involved in a variety

of biological processes including embryonic development, cell growth, morphogenesis, tissue

repair, tumor growth and invasion. This gene was identified by its similarity with mouse

fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent

amplification of this gene has been found in human tumors, which may be important for neoplastic

transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested

the role in inner ear formation. [provided by RefSeq]

UniProtKB/Swiss-Prot: FGF3_HUMAN, P11487

Function: Could be involved in ear development

Gene Wiki entry for FGF3

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the FGF3 gene

Entrez Gene cytogenetic band: 11q13 Ensembl cytogenetic band: 11q13.3 HGNC cytogenetic band: 11q13

FGF3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11M069333: (about GC identifiers)

Start:	69,333,917 bp from pter
End:	69,343,129 bp from pter
Size:	9,213 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000011.8 NT_078088.3

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: FGF3_HUMAN, P11487 (See protein sequence)

Recommended Name: INT-2 proto-oncogene protein precursor

Size: 239 amino acids; 26887 Da

Secondary accessions: Q0VG69

REFSEQ proteins: NP_005238.1

ENSEMBL proteins:

ENSP00000334122

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	R&D Systems Recombinant & Natural Proteins for FGF3 (FGF-3)
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (FGF3)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	TAS	2470007

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Antibodies for FGF3:

	Invitrogen Antibodies for FGF3
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for FGF3
	R&D Systems Antibodies for FGF3 (FGF-3)
	Antibodies from Abcam (FGF3), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for FGF3

Assays for FGF3:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P11487

ProtoNet protein and cluster: P11487

2 Blocks protein families:

IPB002209 Heparin binding growth factor family signature

IPB002348 IL1/HBGF family signature

UniProtKB/Swiss-Prot: FGF3_HUMAN, P11487

Similarity: Belongs to the heparin-binding growth factors family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (FGF3)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_005247

Applied Biosystems Silencer® siRNAs for FGF3

Sigma-Aldrich siRNA and siRNA Panels for FGF3

Sigma-Aldrich shRNA for FGF3

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_005247
Myc/DDK tagged cDNA clone in CMV expression vector: NM_005247
untagged cDNA clone in CMV expression vector: NM_005247

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_005247

UniProtKB/Swiss-Prot: FGF3_HUMAN, P11487

Function: Could be involved in ear development

Genatlas biochemistry entry for FGF3:

fibroblast growth factor 3,basic,expressed during embryonic development

11 MGI mutant phenotypes (inferred from 4 alleles) (MGI details for Fgf3):

behavior/neurological	embryogenesis	growth/size	hearing/vestibular/ear	lethality-postnatal
lethality-prenatal/perinatal	life span-post-weaning/aging	limbs/digits/tail	nervous system	reproductive system
skeleton

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	16263090
GO:0008083	growth factor activity	TAS	2470007

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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4 Sigma-Aldrich "Your Favorite Gene" Pathways for FGF3 (Your Favorite Gene powered by Ingenuity)

Actin Cytoskeleton Signaling
Bladder Cancer Signaling
FGF Signaling
Clathrin-mediated Endocytosis

GeneDecks FGF3 for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for FGF3

5/61 Interacting proteins for FGF3 (ENSP00000334122³) via UniProtKB, MINT, and/or STRING (see all 61 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
FGFR1	ENSP00000311337³	STRING (score=.999)
FGFR2	ENSP00000333090³	STRING (score=.999)
FGFR3	ENSP00000354170³	STRING (score=.999)
FGFR4	ENSP00000366412³	STRING (score=.999)
EBNA1BP2	ENSP00000236051³	STRING (score=.971)

About this table

5/7 Gene Ontology (GO) biological process terms (links to tree view) (see all 7 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001759	induction of an organ	IEA	--
GO:0007165	signal transduction	TAS	2470007
GO:0007267	cell-cell signaling	TAS	2470007
GO:0008283	cell proliferation	IEA	--
GO:0008543	fibroblast growth factor receptor signaling pathway	EXP	17133345

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for FGF3
3 Novoseek chemical compound relationships for FGF3 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
bamhi	29.72	2	1975511 (1), 1362493 (1)
oligonucleotide	0.00	1	8559598 (1)
steroid	0.00	1	1350457 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (FGF3)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_005247

Sigma-Aldrich siRNA and siRNA Panels for FGF3

Sigma-Aldrich shRNA for FGF3

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_005247

REFSEQ mRNAs for FGF3 gene:

NM_005247.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_005247

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_005247
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_005247
                                 untagged cDNA clone in CMV expression vector: NM_005247

Additional cDNA sequence: BC113739.1

1 DOTS entry:

DT.95313645

1 AceView cDNA sequence:

NM_005247

highest scoring ESTs for FGF3:

NM_005247 BC113739 H45899 X14445

Unigene Cluster for FGF3:

Fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog)

Hs.37092

Unigene Representative Sequence: NM_005247

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000334134

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

FGF3 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for FGF3

¹ / ² / ³

3 probe-sets matching FGF3 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
1855_at²^{, 3}	U95-A	2	1.00	0.97	1.00	1.00	X14445	0.20	1.00	0.72	1
214571_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_005247	0.60	1.00	0.82	1
214571_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.37092

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for FGF3 gene from 5/7 species (see all 7 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
chimpanzee (Pan troglodytes)	FGF3¹	--	fibroblast growth factor 3 (murine mammary tumor virus more	99.3(n) 98.74(a)	466693 XM_522092.2 XP_522092.2
cow (Bos taurus)	FGF3¹	--	fibroblast growth factor 3 (murine mammary tumor virus more	87.13(n) 88.37(a)	618481 XM_870814.2 XP_875907.2
rat (Rattus norvegicus)	Fgf3¹	--	fibroblast growth factor 3	85.41(n) 90.78(a)	170633 NM_130817.1 NP_570830.1
mouse (Mus musculus)	Fgf3^{1, 5}	7 (72.40 cM)⁵	fibroblast growth factor 3^{1, 5}	84.33(n)¹ 89.4(a)¹	14174¹ NM_008007.1¹ NP_032033.1¹ AK021062⁵ AK133901⁵ (see all 13)
chicken (Gallus gallus)	FGF3¹	--	fibroblast growth factor 3 (murine mammary tumor virus more	69.81(n) 78.3(a)	396267 NM_205327.1 NP_990658.1

About this table Species with no ortholog for FGF3

ENSEMBL Gene Tree for FGF3

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for FGF3 gene

FGF1² FGF2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/88 NCBI SNPs in FGF3 are shown (see all 88 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 48)

AB	SNP ID	Valid	Chr 11 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs734102^1,2	A,C,F,H	69333663(-)	`TGTGTG/ACGTGG`	1	--	ng5¹		5		EU EA WA	592
	rs11602512^1,2	A,F,H	69333464(+)	`AGTAAC/ACTCTC`	1	--	ng5¹		3		EA WA	262
	rs3926884^1,2	A,C,F	69345004(-)	`GGTGTA/GGAGCA`	1	--	ng3¹		1		EA	172
--	rs7926173^1,2	A,C	69343370(+)	`GCGGCA/GGGGAG`	1	--	ng3¹		0	--	--	--	--
--	rs12364651^1,2	A	69343873(+)	`GGGAAG/TGGGTG`	1	--	ng3¹		0	--	--	--	--
--	rs11825637^1,2	C	69344993(+)	`CATGCA/CCCTCC`	1	--	ng3¹		0	--	--	--	--
--	rs7110221^1,2	C	69334456(-)	`CACACT/AGAAGT`	1	L/Q	mis¹ ese³		1		EA	172
	rs35420992^1,2	F	69334566(+)	`GACACC/TGTCCG`	1	T/T	syn¹		1		NA	72
	rs10796856^1,2	A,C,F,H	69339614(+)	`CAGCGC/TCCTCC`	1	--	int¹ trp³		4		EU EA WA	418
	rs1893047^1,2	A,C,F,H	69335653(+)	`GGCACG/ATGATC`	1	--	int¹		8		EU EA WA NA	773

About this table

HapMap Linkage Disequilibrium images for FGF3 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 164950 disorders: 610706

UniProtKB/Swiss-Prot: FGF3_HUMAN, P11487

Defects in FGF3 are a cause of congenital deafness with inner ear agenesis microtia and

microdontia [MIM:610706]. This disorder consits of a unique autosomal recessive syndrome

characterized by type I microtia, microdontia, and profound congenital deafness associated with a

complete absence of inner ear structures (Michel aplasia)

10/32 Novoseek disease relationships for FGF3 gene (see all 32 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
hypochondroplasia	70.04	2	11057021 (1), 16020314 (1)
parathyroid diseases	51.25	5	11751068 (2), 9597922 (1)
mammary tumor	47.94	6	11095248 (1), 1317463 (1), 7679760 (1), 8559598 (1)
breast cancer	46.16	26	10619258 (2), 7740653 (2), 8585979 (2), 1362493 (2) (see all 17)
tumors	43.35	42	9316622 (2), 17198565 (2), 12201868 (2), 11568558 (2) (see all 26)
carcinoma squamous cell	42.97	3	9858651 (1), 2193294 (1), 7685625 (1)
allelic loss	42.17	1	8509434 (1)
achondroplasia	41.91	1	11057021 (1)
breast carcinoma	39.71	9	8100712 (2), 1975511 (1), 1362493 (1), 9329619 (1) (see all 6)
retinoblastoma	31.44	2	9296509 (1), 16020314 (1)

About this table

Human Gene Mutation Database: FGF3
Tumor Gene Database: FGF3
Breast Cancer Gene Database: FGF3

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/152 PubMed articles for FGF3 gene (see all 152 ):

Homozygous mutations in fibroblast growth factor 3 are associated with a new form of syndromic deafness characterized by inner ear agenesis, microtia, and microdontia. (PubMed id 17236138)^{1, 3, 4} Tekin M....Akar N. (2007)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Sequence organization of the human int-2 gene and its expression in teratocarcinoma cells. (PubMed id 2470007)^{3, 4} Brooks S.... Peters G. (1989)
Fibroblast growth factor 3, a protein with a dual subcellular fate, is interacting with human ribosomal protein S2. (PubMed id 16263090)^{1, 3} Antoine M....Kiefer P. (2005)
Homozygous FGF3 mutations result in congenital deafness with inner ear agenesis, microtia, and microdontia. (PubMed id 18435799)^{1, 3} Tekin M....Duman D. (2008)
Syndromic congenital sensorineural deafness, microtia and microdontia resulting from a novel homoallelic mutation in fibroblast growth factor 3 (FGF3). (PubMed id 18701883)^{1, 3} Alsmadi O....Al-Sayed M. (2009)
Regulation of FGF-3 gene expression in tumorigenic and non-tumorigenic clones of a human colon carcinoma cell line. (PubMed id 10749884)^{1, 3} Galdemard C....Lavialle C. (2000)
SNP genome scanning localizes oto-dental syndrome to chromosome 11q13 and microdeletions at this locus implicate FGF3 in dental and inner-ear disease and FADD in ocular coloboma. (PubMed id 17656375)^{1, 3} Gregory-Evans C.Y....Gregory-Evans K. (2007)
Impaired FGF signaling contributes to cleft lip and palate. (PubMed id 17360555)^{1, 3} Riley B.M....Murray J.C. (2007)
A genome-wide association study identifies protein quantitative trait loci (pQTLs). (PubMed id 18464913)³ Melzer D....Ferrucci L. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 2248	HGNC: 3681	AceView: FGF3	Ensembl:ENSG00000186895	euGenes: HUgn2248
ECgene: FGF3	H-InvDB: FGF3

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for FGF3	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for FGF3
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for FGF3:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for FGF3-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for FGF3		Antibodies for FGF3
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for FGF3		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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	Custom Service for Rabbit Pab from Full-length Protein

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Search Tocris compounds for FGF3

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Search Novus for antibodies for FGF3

GeneCards Homepage - Last full update: 1 Jul 2009 Incremental update: 13 Oct 2009

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The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
FGF3 Gene at Home site.
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FGF3 Gene

protein-coding GIFtS: 57

Aliases &
Descriptions
for FGF3

Summaries
for FGF3

Genomic Location
for FGF3

Proteins
for FGF3

Protein Domains/
Families
for FGF3

Gene Function
for FGF3

Pathways & Interactions
for FGF3

Drugs & Compounds
for FGF3

Transcripts
for FGF3

Expression
for FGF3

Orthologs
for FGF3

Paralogs
for FGF3

SNPs/Variants
for FGF3

Disorders & Mutations
for FGF3

Medical News
for FGF3

Publications
for FGF3

Search for FGF3

Genome Databases showing FGF3

Other Databases showing FGF3

Specialized Databases showing FGF3

Licensable Technologies
for FGF3

Services
for FGF3

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

FGF3 Gene

protein-coding GIFtS: 57

Aliases & Descriptionsfor FGF3

Summariesfor FGF3

Genomic Locationfor FGF3

Proteinsfor FGF3

Protein Domains/Familiesfor FGF3

Gene Functionfor FGF3

Pathways & Interactionsfor FGF3

Drugs & Compoundsfor FGF3

Transcriptsfor FGF3

Expression for FGF3

Orthologsfor FGF3

Paralogsfor FGF3

SNPs/Variantsfor FGF3

Disorders & Mutationsfor FGF3

Medical Newsfor FGF3

Publicationsfor FGF3

Search for FGF3

Genome Databases showing FGF3

Other Databases showing FGF3

Specialized Databases showing FGF3

Licensable Technologiesfor FGF3

Servicesfor FGF3

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for FGF3

Summaries
for FGF3

Genomic Location
for FGF3

Proteins
for FGF3

Protein Domains/
Families
for FGF3

Gene Function
for FGF3

Pathways & Interactions
for FGF3

Drugs & Compounds
for FGF3

Transcripts
for FGF3

Expression
for FGF3

Orthologs
for FGF3

Paralogs
for FGF3

SNPs/Variants
for FGF3

Disorders & Mutations
for FGF3

Medical News
for FGF3

Publications
for FGF3

Licensable Technologies
for FGF3

Services
for FGF3