Aliases for FGF23 Gene
Aliases for FGF23 Gene
External Ids for FGF23 Gene
- HGNC: 3680
- Entrez Gene: 8074
- Ensembl: ENSG00000118972
- OMIM: 605380
- UniProtKB: Q9GZV9
Previous GeneCards Identifiers for FGF23 Gene
- GC12M004215
- GC12M004369
- GC12M004477
Summaries for FGF23 Gene
-
This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013]
GeneCards Summary for FGF23 Gene
FGF23 (Fibroblast Growth Factor 23) is a Protein Coding gene. Diseases associated with FGF23 include Hypophosphatemic Rickets, Autosomal Dominant and Tumoral Calcinosis, Hyperphosphatemic, Familial. Among its related pathways are GPCR Pathway and RET signaling. GO annotations related to this gene include growth factor activity and type 1 fibroblast growth factor receptor binding. An important paralog of this gene is FGF21.
UniProtKB/Swiss-Prot for FGF23 Gene
-
Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FGF23 Gene
Genomics for FGF23 Gene
Regulatory Elements for FGF23 Gene
Enhancers for FGF23 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH12G004439 | 1.1 | Ensembl ENCODE | 10.8 | -61.5 | -61527 | 2.9 | KLF17 FEZF1 EGR2 ZNF362 REST ZNF488 ZEB2 ZNF398 ZNF843 SMARCA4 | C12orf4 FGF23 RAD51AP1 FGF6 |
| GH12G004414 | 0.9 | Ensembl ENCODE | 11.4 | -35.4 | -35432 | 0.9 | ZNF280D L3MBTL2 NRF1 BHLHE40 MNT REST EP300 GATA3 PBX2 IKZF1 | FGF6 FGF23 C12orf4 RAD51AP1 |
| GH12G004506 | 0.8 | ENCODE | 11.1 | -127.5 | -127489 | 1.8 | ELF3 SOX13 FOXA2 TBL1XR1 SAP130 MLX ZNF644 YY1 ARID3A NCOR1 | FGF6 FGF23 C12orf4 RAD51AP1 TIGAR |
| GH12G004305 | 0.7 | dbSUPER | 11 | +74.0 | 74007 | 0.9 | HDAC1 PKNOX1 RAD21 GATA3 POLR2A HES1 RNF2 L3MBTL2 NRF1 BHLHE40 | FGF23 PIR44232 TIGAR |
| GH12G004302 | 0.7 | ENCODE dbSUPER | 11 | +76.4 | 76374 | 1.8 | SMARCA4 POLR2A RBFOX2 | FGF23 PIR44232 TIGAR |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FGF23 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the FGF23 gene promoter:
Regulatory Element Products
Genomic Location for FGF23 Gene
- Chromosome:
- 12
- Start:
- 4,368,227 bp from pter
- End:
- 4,379,728 bp from pter
- Size:
- 11,502 bases
- Orientation:
- Minus strand
Genomic View for FGF23 Gene
Genes around FGF23 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12p13.32 by Ensembl
- 12p13.32 by Entrez Gene
- 12p13.32 by HGNC
FGF23 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FGF23 Gene
Proteins for FGF23 Gene
-
Protein details for FGF23 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9GZV9-FGF23_HUMAN
- Recommended name:
- Fibroblast growth factor 23
- Protein Accession:
- Q9GZV9
- Q4V758
Protein attributes for FGF23 Gene
- Size:
- 251 amino acids
- Molecular mass:
- 27954 Da
- Quaternary structure:
-
- Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by KL and heparan sulfate glycosaminoglycans that function as coreceptors (By similarity).
Protein Expression for FGF23 Gene
Post-translational modifications for FGF23 Gene
- Following secretion this protein is inactivated by cleavage into a N-terminal fragment and a C-terminal fragment. The processing is effected by proprotein convertases.
- O-glycosylated by GALT3. Glycosylation is necessary for secretion; it blocks processing by proprotein convertases when the O-glycan is alpha 2,6-sialylated. Competition between proprotein convertase cleavage and block of cleavage by O-glycosylation determines the level of secreted active FGF23.
- Glycosylation at Thr178
- Modification sites at PhosphoSitePlus
Other Protein References for FGF23 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for FGF23
- R&D Systems Antibodies for FGF23 (FGF-23)
-
Custom Antibody ServicesOriGene Antibodies for FGF23
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-
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- Invitrogen Antibodies for FGF23
- antibodies-online Antibodies for FGF23: See all 93
- GeneTex FGF23 antibody for FGF23
Protein Products
- R&D Systems Proteins and Enzymes for FGF23 (FGF-23)
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- ProSpec Recombinant Proteins for FGF23
-
Cloud-Clone Corp. Proteins for FGF23
- antibodies-online Proteins for FGF23: See all 65
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Assay Products
- R&D Systems Luminex Assays, ELISAs, and other biochemical assays for FGF23 (FGF-23)
-
Cloud-Clone Corp Assay Kits for FGF23
- antibodies-online Kits for FGF23: See all 52
No data available for DME Specific Peptides for FGF23 Gene
Domains & Families for FGF23 Gene
Protein Domains for FGF23 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for FGF23 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9GZV9- Family:
-
- Belongs to the heparin-binding growth factors family.
No data available for Gene Families for FGF23 Gene
Function for FGF23 Gene
Molecular function for FGF23 Gene
- UniProtKB/Swiss-Prot Function:
- Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.
LifeMap Function Summary for FGF23 Gene
During embryonic development, FGF23 as signaling molecule is secreted from the following cells
- Bone
It affects the following cells:
- Bone
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004713 | protein tyrosine kinase activity | TAS | -- |
| GO:0005088 | Ras guanyl-nucleotide exchange factor activity | TAS | -- |
| GO:0005104 | fibroblast growth factor receptor binding | IEA | -- |
| GO:0005105 | type 1 fibroblast growth factor receptor binding | IEA | -- |
| GO:0008083 | growth factor activity | IEA | -- |
Phenotypes for FGF23 Gene
- MGI mutant phenotypes for FGF23:
-
inferred from 4 alleles
- mortality/aging
- growth/size/body region phenotype
- immune system phenotype
- homeostasis/metabolism phenotype
- cardiovascular system phenotype
- respiratory system phenotype
- digestive/alimentary phenotype
- reproductive system phenotype
- endocrine/exocrine gland phenotype
- integument phenotype
- limbs/digits/tail phenotype
- skeleton phenotype
- hematopoietic system phenotype
- renal/urinary system phenotype
- GenomeRNAi human phenotypes for FGF23:
-
- Increased vaccinia virus (VACV) infection
- Mildly decreased CFP-tsO45G cell surface transport
- Decreased ionizing radiation sensitivity
- Decreased NF-kappaB reporter expression
- Decreased IL-8 secretion
- Decreased DCP1a protein expression and assembly in processing bodies after arsenite stimulation
- Decreased melanin production
Animal Model Products
-
Taconic Biosciences Mouse Models for FGF23
-
ViGene Biosciences lentiviral particle packaged cDNA for FGF23 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FGF23 gene
- Search ViGene Biosciences for FGF23
CRISPR Products
-
OriGene CRISPR knockouts for FGF23
-
Santa Cruz Biotechnology (SCBT) CRISPR for FGF23
- GenScript: Design CRISPR guide RNA sequences for FGF23
miRNA for FGF23 Gene
- miRTarBase miRNAs that target FGF23
miRNA Products
- Search ViGene Biosciences for FGF23
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FGF23
- Browse OriGene Inhibitory RNA Products For FGF23
-
ViGene Biosciences ready-to-package AAV shRNAs for FGF23 gene
Clone Products
-
OriGene ORF clones in human for FGF23
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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Cell Line Products
-
Horizon Cell Lines for FGF23
-
ViGene Biosciences adenoviral particle packaged cDNA for FGF23 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FGF23 gene
-
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Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for FGF23 Gene
Localization for FGF23 Gene
Subcellular locations from UniProtKB/Swiss-Prot for FGF23 Gene
- Secreted. Note=Secretion is dependent on O-glycosylation.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| golgi apparatus | 4 |
| plasma membrane | 2 |
| cytosol | 2 |
| cytoskeleton | 1 |
| nucleus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005615 | extracellular space | ISS | 22261194 |
| GO:0005788 | endoplasmic reticulum lumen | TAS | -- |
| GO:0005796 | Golgi lumen | TAS | -- |
Pathways & Interactions for FGF23 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | RET signaling |
.92
|
.92
|
| 2 | Downstream signaling of activated FGFR2 | ||
| 3 | Apoptotic Pathways in Synovial Fibroblasts |
.74
.66
|
.65
.61
.60
.57
|
| 4 | Negative regulation of FGFR1 signaling | ||
| 5 | GPCR Pathway |
.73
.62
|
.55
|
Pathways by source for FGF23 Gene
3 BioSystems pathways for FGF23 Gene
109 Reactome pathways for FGF23 Gene
8 KEGG pathways for FGF23 Gene
Interacting Proteins for FGF23 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000165 | MAPK cascade | TAS | -- |
| GO:0006796 | phosphate-containing compound metabolic process | IEA | -- |
| GO:0008543 | fibroblast growth factor receptor signaling pathway | TAS | -- |
| GO:0010966 | regulation of phosphate transport | IDA | 11409890 |
| GO:0010980 | positive regulation of vitamin D 24-hydroxylase activity | IDA | 15040831 |
No data available for SIGNOR curated interactions for FGF23 Gene
Drugs & Compounds for FGF23 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Cholecalciferol | Approved | Nutra | Fat-soluble secosteroids | 875,869 | ||
| Niacin | Approved, Investigational | Nutra | Unknown, Agonist | 923,923 | ||
| Nicotinamide | Approved | Nutra | 919,923 | |||
| Sevelamer | Approved | Pharma | 74 | |||
| Calcitriol | Approved | Nutra | TNF-α and IL-1β production inhibitor, Vitamin D receptor (VDR) agonist | 210 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Transcripts for FGF23 Gene
mRNA/cDNA for FGF23 Gene
- (1) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (6) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FGF23 Gene
CRISPR Products
-
OriGene CRISPR knockouts for FGF23
-
Santa Cruz Biotechnology (SCBT) CRISPR for FGF23
- GenScript: Design CRISPR guide RNA sequences for FGF23
miRNA Products
- Search ViGene Biosciences for FGF23
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FGF23
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-
ViGene Biosciences ready-to-package AAV shRNAs for FGF23 gene
Clone Products
-
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- Sino Biological Human cDNA Clone for FGF23
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
Expression for FGF23 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Bone (Muscoskeletal System)
- Endochondral Osteocytes Rib
- Endochondral Osteocytes Autopod Periosteum
- Endochondral Osteocytes Vertebrae
- Endochondral Osteocytes Zeugopod Periosteum
- Endochondral Osteoblasts Vertebrae
mRNA differential expression in normal tissues according to GTEx for FGF23 Gene
This gene is overexpressed in Liver (x24.8) and Heart - Atrial Appendage (x17.2).
This gene is overexpressed in Heart (61.0) and Platelet (8.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for FGF23 Gene
NURSA nuclear receptor signaling pathways regulating expression of FGF23 Gene:
FGF23SOURCE GeneReport for Unigene cluster for FGF23 Gene:
Hs.287370mRNA Expression by UniProt/SwissProt for FGF23 Gene:
Q9GZV9-FGF23_HUMAN
Tissue specificity:
Expressed in osteogenic cells particularly during phases of active bone remodeling. In adult trabecular bone, expressed in osteocytes and flattened bone-lining cells (inactive osteoblasts).
Evidence on tissue expression from TISSUES for FGF23 Gene
- Kidney(3)
- Bone(2.8)
- Blood(2.3)
- Thyroid gland(2.3)
- Urine(2.1)
Phenotype-based relationships between genes and organs from Gene ORGANizer for FGF23 Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- cardiovascular
- digestive
- immune
- integumentary
- nervous
- respiratory
- skeletal muscle
- skeleton
- urinary
Organs:
Head and neck:
- brain
- ear
- eye
- head
- jaw
- mandible
- maxilla
- mouth
- neck
- skull
- tooth
Thorax:
- chest wall
- clavicle
- diaphragm
- heart
- rib
- rib cage
- scapula
- sternum
Abdomen:
- biliary tract
- kidney
- liver
Pelvis:
- pelvis
- ureter
Limb:
- ankle
- arm
- digit
- elbow
- femur
- fibula
- finger
- foot
- forearm
- hand
- hip
- humerus
- knee
- lower limb
- radius
- shin
- shoulder
- thigh
- tibia
- toe
- ulna
- upper limb
- wrist
General:
- blood
- blood vessel
- red blood cell
- skin
- spinal column
- vertebrae
- white blood cell
Primer Products
-
OriGene qPCR primer pairs for FGF23
-
OriGene qPCR primer pairs and template standards for FGF23
Orthologs for FGF23 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FGF23 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | FGF23 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | FGF23 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Fgf23 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Fgf23 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | FGF23 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | FGF23 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | FGF23 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | fgf23.1 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | fgf23 34 35 |
|
- Species where no ortholog for FGF23 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for FGF23 Gene
Variants for FGF23 Gene
| SNP ID | Clin | Chr 12 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs104894342 | Likely pathogenic, Tumoral calcinosis, hyperphosphatemic, familial (HFTC) [MIM:211900] | 4,379,372(-) | TCTAC(A/G)GTGAG | reference, missense | |
| rs104894343 | Pathogenic, Tumoral calcinosis, hyperphosphatemic, familial (HFTC) [MIM:211900] | 4,372,622(-) | CTGCA(C/T)GGATT | reference, missense | |
| rs104894344 | Pathogenic, Tumoral calcinosis, hyperphosphatemic, familial (HFTC) [MIM:211900] | 4,370,713(-) | CCACT(C/T)TCCTC | reference, missense | |
| rs104894347 | Pathogenic, Hypophosphatemic rickets, autosomal dominant (ADHR) [MIM:193100] | 4,370,572(-) | ACGGC(A/G)GCACA | reference, missense | |
| rs193922702 | Pathogenic, Hypophosphatemic rickets, autosomal dominant (ADHR) [MIM:193100] | 4,370,563(-) | CACCC(A/G)GAGCG | reference, missense |
Residual Variation Intolerance Score:
40.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.78;
16.34% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FGF23 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FGF23 Gene
Disorders for FGF23 Gene
(52) MalaCards diseases for FGF23 Gene - From: OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| hypophosphatemic rickets, autosomal dominant |
|
|
| tumoral calcinosis, hyperphosphatemic, familial |
|
|
| hyperphosphatemic familial tumoral calcinosis, fgf23-related |
|
|
| hypophosphatemia |
|
|
| hyperphosphatemia |
|
Search FGF23 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
FGF23_HUMAN- Hypophosphatemic rickets, autosomal dominant (ADHR) [MIM:193100]: A disease characterized by isolated renal phosphate wasting, hypophosphatemia, and inappropriately normal 1,25-dihydroxyvitamin D3 (calcitriol) levels. Patients frequently present with bone pain, rickets, and tooth abscesses. {ECO:0000269 PubMed:11062477, ECO:0000269 PubMed:11409890, ECO:0000269 PubMed:16638743}. Note=The disease is caused by mutations affecting the gene represented in this entry.
- Tumoral calcinosis, hyperphosphatemic, familial (HFTC) [MIM:211900]: A severe metabolic disorder that manifests with hyperphosphatemia and massive calcium deposits in the skin and subcutaneous tissues. Some patients manifest recurrent, transient, painful swellings of the long bones associated with the radiographic findings of periosteal reaction and cortical hyperostosis and absence of skin involvement. {ECO:0000269 PubMed:15590700, ECO:0000269 PubMed:16030159, ECO:0000269 PubMed:16151858, ECO:0000269 PubMed:24680727}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Relevant External Links for FGF23
No data available for Genatlas for FGF23 Gene
Publications for FGF23 Gene
- Identification of a novel fibroblast growth factor, FGF-23, preferentially expressed in the ventrolateral thalamic nucleus of the brain. (PMID: 11032749) Yamashita T. … Itoh N. (Biochem. Biophys. Res. Commun. 2000) 2 3 4 22 64
- FGF-23 inhibits renal tubular phosphate transport and is a PHEX substrate. (PMID: 11409890) Bowe A.E. … Schiavi S.C. (Biochem. Biophys. Res. Commun. 2001) 3 4 22 64
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
- A prospective study of fibroblast growth factor-23 in children with chronic kidney disease. (PMID: 19929273) Magnusson P. … Swolin-Eide D. (Scand. J. Clin. Lab. Invest. 2010) 3 22 64
- Early control of PTH and FGF23 in normophosphatemic CKD patients: a new target in CKD-MBD therapy? (PMID: 19965540) Oliveira R.B. … MoysAcs R.M. (Clin J Am Soc Nephrol 2010) 3 22 64
Products for FGF23 Gene
- R&D Systems Antibodies for FGF23 (FGF-23)
- R&D Systems Proteins and Enzymes for FGF23 (FGF-23)
- R&D Systems ELISAs, Luminex Assays, and other biochemical assays for FGF23 (FGF-23)
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- Custom Antibody ServicesOriGene Antibodies for FGF23
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- OriGene qPCR primer pairs and template standards for FGF23
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- Novus Biologicals Antibodies for FGF23
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- Cloud-Clone Corp. Antibodies for FGF23
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- Taconic Biosciences Mouse Models for FGF23
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- antibodies-online Antibodies for FGF23: See all 93
- antibodies-online Kits for FGF23: See all 52
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- GeneTex FGF23 antibody for FGF23
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- ViGene Biosciences adenoviral particle packaged cDNA for FGF23 gene
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- Horizon Cell Lines for FGF23
- Cyagen custom Knockout/knockin (KOKI) mouse models for FGF23
- VectorBuilder custom plasmid, inducible vectors for FGF23
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FGF23
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FGF23 Gene
- (1) GeneCards
- (2) HGNC
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