Aliases for FGF19 Gene
External Ids for FGF19 Gene
- HGNC: 3675
- Entrez Gene: 9965
- Ensembl: ENSG00000162344
- OMIM: 603891
- UniProtKB: O95750
Previous GeneCards Identifiers for FGF19 Gene
- GC11M072007
- GC11M071199
- GC11M069760
- GC11M069285
- GC11M069222
- GC11M069513
- GC11M065805
Summaries for FGF19 Gene
-
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This growth factor is a high affinity, heparin dependent ligand for FGFR4. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development. [provided by RefSeq, Jul 2008]
GeneCards Summary for FGF19 Gene
FGF19 (Fibroblast Growth Factor 19) is a Protein Coding gene. Diseases associated with FGF19 include Diarrhea and Functional Diarrhea. Among its related pathways are GPCR Pathway and RET signaling. GO annotations related to this gene include growth factor activity and fibroblast growth factor receptor binding. An important paralog of this gene is FGF21.
UniProtKB/Swiss-Prot for FGF19 Gene
-
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FGF19 Gene
Genomics for FGF19 Gene
Regulatory Elements for FGF19 Gene
Enhancers for FGF19 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH11G069840 | 1.2 | FANTOM5 ENCODE dbSUPER | 26.3 | -136.2 | -136185 | 0.4 | TFAP4 MXD4 ZIC2 ZNF592 JUND POLR2A ZKSCAN8 GLIS1 ZBTB33 TCF7L2 | FGF3 FGF19 ENSG00000260348 |
| GH11G069700 | 1.5 | Ensembl ENCODE dbSUPER | 0.7 | +2.5 | 2508 | 3.6 | PKNOX1 FOXA2 MLX ARID4B SIN3A DMAP1 YBX1 YY1 ZNF766 CBX5 | ENSG00000246889 ORAOV1 FGF19 |
| GH11G069707 | 1 | ENCODE dbSUPER | 0.7 | 0.0 | -36 | 0.2 | CTCF RB1 ZBTB21 RBBP5 ZIC2 RAD21 GLIS2 PATZ1 SMC3 EZH2 | FGF19 LOC100129779 |
| GH11G069708 | 0.9 | ENCODE | 0.7 | -4.7 | -4667 | 1.1 | PKNOX1 ARID4B DMAP1 ZNF766 ELK1 NCOA1 ZHX2 PPARG KAT8 RCOR2 | FGF19 LOC100129779 |
| GH11G069704 | 0.9 | ENCODE dbSUPER | 0.7 | +0.4 | 365 | 0.2 | KLF1 ZBTB21 ZBTB8A RBBP5 ZFHX2 ZNF766 HDAC2 ZNF629 GLIS1 EZH2 | FGF19 ORAOV1 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FGF19 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the FGF19 gene promoter:
Regulatory Element Products
Genomic Location for FGF19 Gene
- Chromosome:
- 11
- Start:
- 69,698,232 bp from pter
- End:
- 69,704,642 bp from pter
- Size:
- 6,411 bases
- Orientation:
- Minus strand
Genomic View for FGF19 Gene
Genes around FGF19 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q13.3 by Ensembl
- 11q13.3 by Entrez Gene
- 11q13.3 by HGNC
FGF19 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FGF19 Gene
Proteins for FGF19 Gene
-
Protein details for FGF19 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O95750-FGF19_HUMAN
- Recommended name:
- Fibroblast growth factor 19
- Protein Accession:
- O95750
Protein attributes for FGF19 Gene
- Size:
- 216 amino acids
- Molecular mass:
- 24003 Da
- Quaternary structure:
-
- Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by KL, KLB and heparan sulfate glycosaminoglycans that function as coreceptors. Interacts with KL; this interaction is direct. Interacts with KLB; this interaction is direct. Interacts with FGFR4 in the presence of heparin, KL or KLB. Interacts with MALRD1 (PubMed:23747249).
- Miscellaneous:
-
- Contrarily to other members of the family that can bind several FGF receptors FGF19 is specific for FGFR4.
Protein Expression for FGF19 Gene
Post-translational modifications for FGF19 Gene
Other Protein References for FGF19 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for FGF19 (FGF-19)
- Cell Signaling Technology (CST) Antibodies for FGF19 (FGF19)
-
Custom Antibody ServicesOriGene Antibodies for FGF19
- Novus Biologicals Antibodies for FGF19
-
Abcam antibodies for FGF19
-
Cloud-Clone Corp. Antibodies for FGF19
- Invitrogen Antibodies for FGF19
- antibodies-online Antibodies for FGF19: See all 82
- GeneTex FGF19 antibody for FGF19
-
Santa Cruz Biotechnology (SCBT) Antibodies for FGF19
Protein Products
- R&D Systems Proteins and Enzymes for FGF19 (FGF-19)
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- Sino Biological Recombinant Proteins for FGF19
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- ProSpec Recombinant Proteins for FGF19
-
Cloud-Clone Corp. Proteins for FGF19
- antibodies-online Proteins for FGF19: See all 46
- Search antibodies-online for peptides
- GeneTex Proteins for FGF19
-
Abcam proteins for FGF19
Assay Products
-
Custom Assay ServicesOriGene ELISA Kits for FGF19
- R&D Systems Proteome Profiler Antibody Arrays, ELISAs, and other biochemical assays for FGF19 (FGF-19)
- antibodies-online Kits for FGF19: See all 31
-
Abcam assays for FGF19
No data available for DME Specific Peptides for FGF19 Gene
Domains & Families for FGF19 Gene
Protein Domains for FGF19 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for FGF19 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O95750- Family:
-
- Belongs to the heparin-binding growth factors family.
No data available for Gene Families for FGF19 Gene
Function for FGF19 Gene
Molecular function for FGF19 Gene
- GENATLAS Biochemistry:
- fibroblast growth factor 19,heparin dependent ligand for FGFR4,expressed in fetal brain,skin,cartilage and retina,gall bladder,potentially playing an important role in brain development,overexpressed in colon adenocarcinoma cell line
- UniProtKB/Swiss-Prot Function:
- Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.
- UniProtKB/Swiss-Prot Induction:
- Induced by the bile acids receptor NR1H4 that binds and activates a NR1H4-responsive element within intron 2.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005088 | Ras guanyl-nucleotide exchange factor activity | TAS | -- |
| GO:0005104 | fibroblast growth factor receptor binding | IPI | 10525310 |
| GO:0005515 | protein binding | IPI | 18829467 |
| GO:0008083 | growth factor activity | IEA | -- |
| GO:0016303 | 1-phosphatidylinositol-3-kinase activity | TAS | -- |
Phenotypes for FGF19 Gene
- MGI mutant phenotypes for FGF19:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for FGF19:
Animal Model Products
-
Taconic Biosciences Mouse Models for FGF19
-
ViGene Biosciences lentiviral particle packaged cDNA for FGF19 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FGF19 gene
- Search ViGene Biosciences for FGF19
CRISPR Products
-
OriGene CRISPR knockouts for FGF19
-
Santa Cruz Biotechnology (SCBT) CRISPR for FGF19
- GenScript: Design CRISPR guide RNA sequences for FGF19
miRNA for FGF19 Gene
- miRTarBase miRNAs that target FGF19
-
- hsa-mir-5572 (MIRT639612)
- hsa-mir-607 (MIRT639613)
- hsa-mir-6855-5p (MIRT639614)
- hsa-mir-3170 (MIRT639615)
- hsa-mir-6819-5p (MIRT639616)
- hsa-mir-6812-5p (MIRT639617)
- hsa-mir-3671 (MIRT639618)
- hsa-mir-6737-5p (MIRT639619)
- hsa-mir-193a-5p (MIRT639620)
- hsa-mir-7704 (MIRT639621)
- hsa-mir-615-5p (MIRT639622)
- hsa-mir-627-3p (MIRT639623)
- hsa-mir-676-5p (MIRT639624)
- hsa-mir-4762-5p (MIRT639625)
- hsa-mir-7152-5p (MIRT648599)
- hsa-mir-3074-5p (MIRT648600)
- hsa-mir-1200 (MIRT648601)
- hsa-mir-378a-5p (MIRT648602)
- hsa-mir-29a-5p (MIRT648603)
miRNA Products
- Search ViGene Biosciences for FGF19
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FGF19
- Browse OriGene Inhibitory RNA Products For FGF19
-
ViGene Biosciences ready-to-package AAV shRNAs for FGF19 gene
Clone Products
-
OriGene ORF clones in human for FGF19
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- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
Horizon Cell Lines for FGF19
-
ViGene Biosciences adenoviral particle packaged cDNA for FGF19 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FGF19 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FGF19 gene
Flow Cytometry Products
- eBioscience FlowRNA Probe Sets (VA1-13136) for FGF19
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for FGF19 Gene
Localization for FGF19 Gene
Subcellular locations from UniProtKB/Swiss-Prot for FGF19 Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| nucleus | 2 |
| peroxisome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005622 | intracellular | IEA | -- |
Pathways & Interactions for FGF19 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | RET signaling |
.92
|
.92
|
| 2 | Apoptotic Pathways in Synovial Fibroblasts |
.74
.66
|
.65
.61
.60
.57
|
| 3 | GPCR Pathway |
.73
.62
|
.55
|
| 4 | GAB1 signalosome |
.89
|
|
| 5 | Downstream signaling of activated FGFR2 | ||
Pathways by source for FGF19 Gene
4 BioSystems pathways for FGF19 Gene
70 Reactome pathways for FGF19 Gene
8 KEGG pathways for FGF19 Gene
1 GeneGo (Thomson Reuters) pathway for FGF19 Gene
Interacting Proteins for FGF19 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000165 | MAPK cascade | TAS | -- |
| GO:0001755 | neural crest cell migration | IEA | -- |
| GO:0001934 | positive regulation of protein phosphorylation | IDA | 17627937 |
| GO:0007399 | nervous system development | TAS | 9931477 |
| GO:0007507 | heart development | IEA | -- |
No data available for SIGNOR curated interactions for FGF19 Gene
Drugs & Compounds for FGF19 Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Transcripts for FGF19 Gene
mRNA/cDNA for FGF19 Gene
- (1) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (25) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FGF19 Gene
CRISPR Products
-
OriGene CRISPR knockouts for FGF19
-
Santa Cruz Biotechnology (SCBT) CRISPR for FGF19
- GenScript: Design CRISPR guide RNA sequences for FGF19
miRNA Products
- Search ViGene Biosciences for FGF19
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FGF19
- Browse OriGene Inhibitory RNA Products For FGF19
-
ViGene Biosciences ready-to-package AAV shRNAs for FGF19 gene
Clone Products
-
OriGene ORF clones in human for FGF19
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for FGF19
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
- eBioscience FlowRNA Probe Sets (VA1-13136) for FGF19
Expression for FGF19 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Neural Tube (Nervous System)
-
Skeletal Muscle (Muscoskeletal System)
- Mononuclear Myocytes Hyoid Arch Muscles
- Mononuclear Myocytes Mandibular Arch Muscles
- Muscle Progenitor Cells Mandibular Arch Muscles
- Muscle Progenitor Cells Hyoid Arch Muscles
-
Brain (Nervous System)
- Mature Endothelial Cells Blood Brain Barrier
- Cerebellum
-
Eye (Sensory Organs)
- Early Retinal Progenitor Cells Retinal Neuroblastic Layer
- Outer Nuclear Layer
-
Neural Ectoderm (Nervous System)
- Anterior Neural Ridge Cells Neural Plate
-
Epiblast (Early Embryonic Tissues)
- Epiblast Cells Epiblast
-
Endothelium (Cardiovascular System)
- Mature Endothelial Cells Blood Brain Barrier
-
Gall Bladder (Hepatobiliary System)
mRNA differential expression in normal tissues according to GTEx for FGF19 Gene
This gene is overexpressed in Small Intestine - Terminal Ileum (x23.5), Liver (x7.4), Pituitary (x4.6), and Testis (x4.3).
This gene is overexpressed in Islet of Langerhans (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for FGF19 Gene
NURSA nuclear receptor signaling pathways regulating expression of FGF19 Gene:
FGF19SOURCE GeneReport for Unigene cluster for FGF19 Gene:
Hs.249200mRNA Expression by UniProt/SwissProt for FGF19 Gene:
O95750-FGF19_HUMAN
Tissue specificity:
Expressed in fetal brain, cartilage, retina, and adult gall bladder.
Evidence on tissue expression from TISSUES for FGF19 Gene
- Intestine(4.5)
- Nervous system(4.4)
- Gall bladder(3)
- Liver(2.1)
Primer Products
-
OriGene qPCR primer pairs for FGF19
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for FGF19 Gene
Orthologs for FGF19 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FGF19 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | FGF19 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | FGF19 34 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | FGF19 35 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Fgf19 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Fgf15 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | FGF19 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | FGF19 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | FGF19 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | fgf19 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | fgf19 34 35 |
|
- Species where no ortholog for FGF19 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for FGF19 Gene
Variants for FGF19 Gene
| SNP ID | Clin | Chr 11 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000080485 | -- | 69,697,978(+) | GGCCG(C/T)CCTAA | downstream-variant-500B | |
| rs1000225393 | -- | 69,702,432(+) | TGCGT(-/GTGAGGCCTGCGCGG)GCCGA | intron-variant | |
| rs1001040128 | -- | 69,702,619(+) | CCTGC(C/G)CCCAC | intron-variant | |
| rs1001323860 | -- | 69,702,442(+) | GCCTG(C/T)GCGGG | intron-variant | |
| rs1001352049 | -- | 69,703,207(+) | CGCCC(A/G)GGGAC | intron-variant |
Residual Variation Intolerance Score:
66.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.50;
10.93% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FGF19 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- FGF19
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FGF19 Gene
Disorders for FGF19 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| diarrhea |
|
|
| functional diarrhea |
|
|
| deafness, autosomal recessive 63 |
|
|
Search FGF19 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for FGF19
No data available for UniProtKB/Swiss-Prot and Genatlas for FGF19 Gene
Publications for FGF19 Gene
- FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4. (PMID: 10525310) Xie M.-H. … Gurney A.L. (Cytokine 1999) 2 3 4 22 64
- Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7alpha-hydroxylase gene expression. (PMID: 19085950) Song K.H. … Chiang J.Y. (Hepatology 2009) 3 4 22 64
- Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members. (PMID: 17339340) Goetz R. … Mohammadi M. (Mol. Cell. Biol. 2007) 3 4 22 64
- Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21. (PMID: 17623664) Kurosu H. … Kuro-o M. (J. Biol. Chem. 2007) 3 4 22 64
- The crystal structure of fibroblast growth factor (FGF) 19 reveals novel features of the FGF family and offers a structural basis for its unusual receptor affinity. (PMID: 14730967) Harmer N.J. … Blundell T.L. (Biochemistry 2004) 3 4 22 64
Products for FGF19 Gene
- R&D Systems Antibodies for FGF19 (FGF-19)
- R&D Systems Proteins and Enzymes for FGF19 (FGF-19)
- R&D Systems ELISAs, Proteome Profiler Antibody Arrays, and other biochemical assays for FGF19 (FGF-19)
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- Custom Antibody ServicesOriGene Antibodies for FGF19
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- OriGene qPCR primer pairs for FGF19
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- GenScript: Next-day shipping cDNA ORF clone for FGF19 in any vector
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- GenScript: Design CRISPR guide RNA sequences for FGF19
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- Search for Antibodies & Assays
- Sino Biological Human cDNA Clone for FGF19
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for FGF19
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- Novus Biologicals
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- Abcam antibodies for FGF19
- Abcam proteins for FGF19
- Abcam assays for FGF19
- Find your target
- Search knockout validated antibodies
- Browse monoclonal antibodies
- ProSpec Recombinant Proteins for FGF19
- Cloud-Clone Corp. Antibodies for FGF19
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- Taconic Biosciences Mouse Models for FGF19
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- antibodies-online Antibodies for FGF19: See all 82
- antibodies-online Kits for FGF19: See all 31
- antibodies-online Proteins for FGF19: See all 46
- Search antibodies-online for peptides
- GeneTex FGF19 antibody for FGF19
- GeneTex Proteins for FGF19
- ViGene Biosciences adenoviral particle packaged cDNA for FGF19 gene
- ViGene Biosciences lentiviral particle packaged cDNA for FGF19 gene
- ViGene Biosciences ready-to-package AAV shRNAs for FGF19 gene
- Search ViGene Biosciences for FGF19
- Santa Cruz Biotechnology (SCBT) Antibodies for FGF19
- Search Santa Cruz Biotechnology (SCBT) for FGF19 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for FGF19
- Horizon Cell Lines for FGF19
- Cyagen custom Knockout/knockin (KOKI) mouse models for FGF19
- VectorBuilder custom plasmid, inducible vectors for FGF19
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FGF19
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FGF19 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
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