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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FGF16 Gene

protein-coding   GIFtS: 53
GCID: GC0XP076709

Fibroblast Growth Factor 16

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Fibroblast Growth Factor 161 2
FGF-162 3

External Ids:    HGNC: 36721   Entrez Gene: 88232   Ensembl: ENSG000001964687   OMIM: 3008275   UniProtKB: O433203   

Export aliases for FGF16 gene to outside databases

Previous GC identifers: GC00U990451 GC13P020043 GC0XP076516 GC0XP070299


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FGF16 Gene:
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members
possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes,
including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The rat
homolog is predominantly expressed in embryonic brown adipose tissue and has significant mitogenic activity,
which suggests a role in proliferation of embryonic brown adipose tissue. (provided by RefSeq, Jul 2008)

GeneCards Summary for FGF16 Gene: 
FGF16 (fibroblast growth factor 16) is a protein-coding gene. Diseases associated with FGF16 include endotheliitis, and melanoma, and among its related super-pathways are Regulation of actin cytoskeleton and Development FGF-family signaling. GO annotations related to this gene include growth factor activity. An important paralog of this gene is FGF12.

UniProtKB/Swiss-Prot: FGF16_HUMAN, O43320
Function: Plays an important role in the regulation of embryonic development, cell proliferation and cell
differentiation, and is required for normal cardiomyocyte proliferation and heart development




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.2  NT_011651.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FGF16 gene promoter:
         TBP   GATA-3   Tal-1   FOXO3   FOXO3b   Gfi-1   E47   FOXO3a   TGIF   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFGF16 promoter sequence
   Search SABiosciences Chromatin IP Primers for FGF16

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FGF16


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq13   Ensembl cytogenetic band:  Xq21.1   HGNC cytogenetic band: Xq21.1

FGF16 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FGF16 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP076709:  view genomic region     (about GC identifiers)

Start:
76,709,645 bp from pter      End:
76,712,769 bp from pter
Size:
3,125 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: FGF16_HUMAN, O43320 (See protein sequence)
Recommended Name: Fibroblast growth factor 16  
Size: 207 amino acids; 23759 Da
Subunit: Interacts with FGFR1 and FGFR2
Subcellular location: Secreted (By similarity)

Explore the universe of human proteins at neXtProt for FGF16: NX_O43320

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O43320

  • FGF16 Protein expression data from MOPED1, PaxDb2 and MAXQB3 : --
    REFSEQ proteins: NP_003859.1  
    ENSEMBL proteins: 
     ENSP00000399324  
    Reactome Protein details: O43320
    Human Recombinant Protein Products for FGF16: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for FGF16 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0005615extracellular space TAS9473496

    FGF16 for ontologies           About GeneDecksing



    FGF16 Antibody Products: 
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    LSBio Antibodies in human, mouse, rat for FGF16 

    Assay Products for FGF16: 
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for FGF16 
    Cloud-Clone Corp. CLIAs for FGF16


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR002348 IL1_HBGF
     IPR008996 Cytokine_IL1-like
     IPR002209 GF_heparin-bd

    Graphical View of Domain Structure for InterPro Entry O43320

    ProtoNet protein and cluster: O43320

    2 Blocks protein domains:
    IPB002209 Heparin binding growth factor family signature
    IPB002348 IL1/HBGF family signature


    UniProtKB/Swiss-Prot: FGF16_HUMAN, O43320
    Similarity: Belongs to the heparin-binding growth factors family


    FGF16 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FGF16_HUMAN, O43320
    Function: Plays an important role in the regulation of embryonic development, cell proliferation and cell
    differentiation, and is required for normal cardiomyocyte proliferation and heart development

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005104fibroblast growth factor receptor binding IEA--
    GO:0008083growth factor activity IEA--
         
    FGF16 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for FGF16:
     Lamellipodia cells 

         11 MGI mutant phenotypes (inferred from 4 alleles(MGI details for Fgf16):
     behavior/neurological  cardiovascular system  cellular  craniofacial  embryogenesis 
     growth/size  hearing/vestibular/ear  mortality/aging  muscle  no phenotypic analysis 
     reproductive system 

    FGF16 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Fgf16tm1Nit for FGF16

       inGenious Targeting Laboratory - Custom generated mouse model solutions for FGF16 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for FGF16

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FGF16 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FGF16 

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    Clone
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for FGF16 About   (see all 31)                                                                                              See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Regulation of Actin Cytoskeleton
    Regulation of Actin Cytoskeleton0.57
    Regulation of actin cytoskeleton0.57
    2Development FGF-family signaling
    Development FGF-family signaling0.63
    FGF Pathway0.38
    3Apoptotic Pathways in Synovial Fibroblasts
    Mitochondrial Apoptosis0.85
    Rac1 Pathway0.65
    Cellular Apoptosis Pathway0.85
    Glioma Invasiveness0.64
    Apoptotic Pathways in Synovial Fibroblasts0.84
    Actin-Based Motility by Rho Family GTPases0.62
    p53 Mediated Apoptosis0.84
    ERK5 Signaling0.61
    4FGFR2c ligand binding and activation
    FGFR ligand binding and activation0.79
    FGFR2 ligand binding and activation0.76
    SHC-mediated cascade0.79
    Signaling by FGFR2 mutants0.76
    FGFR2c ligand binding and activation0.79
    Activated point mutants of FGFR20.76
    FGFR3c ligand binding and activation0.79
    FGFR4 ligand binding and activation0.73
    5Signaling by FGFR
    Downstream signaling of activated FGFR0.92
    Downstream signal transduction0.90
    Signaling by FGFR0.92
    Signaling by PDGF0.85
    Signaling by FGFR in disease0.91
    Signaling by EGFR0.84
    DAP12 signaling0.91
    Signaling by EGFR in Cancer0.83

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 EMD Millipore Pathway for FGF16
        Development FGF-family signaling

    5/59 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for FGF16 (see all 59)
        Nuclear Receptor Activation by Vitamin-A
    Paxillin Interactions
    Telomerase Components in Cell Signaling
    Mitochondrial Apoptosis
    Molecular Mechanisms of Cancer

    1 GeneGo (Thomson Reuters) Pathway for FGF16
        Development FGF-family signaling

    1 BioSystems Pathway for FGF16
        Regulation of Actin Cytoskeleton


    5/54        Reactome Pathways for FGF16 (see all 54)
        FGFR2 ligand binding and activation
    FGFR ligand binding and activation
    Signaling by EGFR in Cancer
    Signaling by FGFR2 mutants
    Downstream signal transduction


    5/6         Kegg Pathways  (Kegg details for FGF16) (see all 6):
        MAPK signaling pathway
    PI3K-Akt signaling pathway
    Regulation of actin cytoskeleton
    Pathways in cancer
    Proteoglycans in cancer


    FGF16 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FGF16

    Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction TAS9473496
    GO:0007173epidermal growth factor receptor signaling pathway TAS--
    GO:0007267cell-cell signaling TAS9473496
    GO:0008152metabolic process TAS9473496
    GO:0008286insulin receptor signaling pathway TAS--

    FGF16 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FGF16

    Search CenterWatch for drugs/clinical trials and news about FGF16

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for FGF16 gene: 
    NM_003868.1  

    Unigene Cluster for FGF16:

    Fibroblast growth factor 16
    Hs.666364
    Unigene Representative Sequence: NM_003868
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000439435(uc011mqp.2)
    miRNA
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    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for FGF16
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FGF16
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    OriGene clones in human, mouse for FGF16 (see all 6)
    OriGene ORF clones in mouse, rat for FGF16
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    GenScript: all cDNA clones in your preferred vector: FGF16 (NM_003868)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FGF16
    Sirion Biotech Customized lentivirus for stable overexpression of FGF16 
                         Customized lentivirus expression plasmids for stable overexpression of FGF16 
    Primer
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    OriGene qPCR primer pairs and template standards for FGF16
    OriGene qSTAR qPCR primer pairs in human, mouse for FGF16
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FGF16
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FGF16
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FGF16

    Additional mRNA sequence: AB009391.1 

    1 DOTS entry:

    DT.92010031 

    2 AceView cDNA sequences:

    AB009391 NM_003868 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FGF16 expression in normal human tissues (normalized intensities)      FGF16 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCCAGAGACC
    FGF16 Expression
    About this image


    FGF16 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Adipose (Muscoskeletal System)    fully expand to see all 4 entries
             Lumbar Committed Brown Preadipocytes Lumbar Brown Adipose Depot
     
     Heart (Cardiovascular System)

    Genevestigator expression for FGF16

    SOURCE GeneReport for Unigene cluster: Hs.666364
        SABiosciences Custom PCR Arrays for FGF16
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for FGF16 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fgf161 , 5 fibroblast growth factor 161, 5 95.33(n)1
    99.52(a)1
      X (47.20 cM)5
    809031  NM_030614.21  NP_085117.21 
     1057642795 
    chicken
    (Gallus gallus)
    Aves FGF161 fibroblast growth factor 16 82.13(n)
    90.34(a)
      422330  NM_001044650.1  NP_001038115.1 
    lizard
    (Anolis carolinensis)
    Reptilia FGF166
    Uncharacterized protein
    93(a)
    1 ↔ 1
    GL343420.1(843947-846255)
    zebrafish
    (Danio rerio)
    Actinopterygii fgf161 fibroblast growth factor 16 72.91(n)
    80.3(a)
      692065  NM_001040407.1  NP_001035497.1 


    ENSEMBL Gene Tree for FGF16 (if available)
    TreeFam Gene Tree for FGF16 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FGF16 gene
    FGF122  FGF52  FGF202  FGF42  FGF62  FGF92  FGF32  FGF72  
    FGF112  FGF102  FGF132  FGF222  FGF142  
    18/19 SIMAP similar genes for FGF16 using alignment to 2 protein entries:     FGF16_HUMAN (see all proteins) (see all similar genes):
    FGF9    FGF20    FGF10    FGF7    KGFLP1    KGFLP2
    FGF12    FGF22    PRED3    FGF14    FGF3    fgf gene
    FGF1    FGF11    FGF13    FGF5    FGF6    FGF2

    FGF16 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/80 SNPs in FGF16 are shown (see all 80)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1512490281,2
    --76677526(+) CTCTCA/GCCTAG 1 -- int10--------
    rs1828317791,2
    --76677819(+) TTTGCC/GGGAAA 1 -- int10--------
    rs1865708001,2
    --76678071(+) CTCCTC/TGGTAA 1 -- int10--------
    rs1910789311,2
    --76678246(+) CTACAC/TTCAGA 1 -- int10--------
    rs285109871,2
    C--76678266(+) CTTCCC/TTTCTT 1 -- int1 tfbs3 trp30--------
    rs1832286811,2
    --76678342(+) CCATGA/CCTTGC 1 -- int10--------
    rs1876000031,2
    --76678752(+) ACTCAC/TTGCCG 1 -- int10--------
    rs1930432301,2
    --76678756(+) ATTGCC/TGATAT 1 -- int10--------
    rs1831405061,2
    --76679001(+) TAAGGA/GTGTTA 1 -- int10--------
    rs2021686311,2
    --76679020(+) AGAAA-/CTT   
       AACAC
    CCAAA
    1 -- int10--------

    HapMap Linkage Disequilibrium report for FGF16 (76709645 - 76712769 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for FGF16: --
    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing FGF16
    DNA2.0 Custom Variant and Variant Library Synthesis for FGF16

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 300827    OMIM disorders: --

    5 diseases for FGF16:    About MalaCards
    endotheliitis    melanoma    adenocarcinoma    breast cancer
    pancreatitis


    FGF16 for disorders           About GeneDecksing


    Export disorders for FGF16 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FGF16 gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with FGF16)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Structure and expression of a novel member, FGF-16, on the fibroblast growth factor family. (PubMed id 9473496)1, 2, 3 Miyake A.... Itoh N. (1998)
    2. Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. (PubMed id 16597617)1, 2 Zhang X....Ornitz D.M. (2006)
    3. The human FGF gene family: chromosome location and phylogenetic analysis. (PubMed id 11474196)1, 3 Kim H.S. (2001)
    4. Fibroblast growth factor 16 and 18 are expressed in human cardiovascular tissues and induce on endothelial cells migration but not proliferation. (PubMed id 16756958)1, 9 Antoine M....Kiefer P. (2006)
    5. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    6. FGF-16 is a target for adrenergic stimulation through NF-kappaB activation in postnatal cardiac cells and adult mouse heart. (PubMed id 20097674)1 Sofronescu A.G....Cattini P.A. (2010)
    7. Fibroblast growth factor signalling: from development to cancer. (PubMed id 20094046)2 Turner N. and Grose R. (2010)
    8. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
    9. Differential signal transduction of alternatively spliced FGFR2 variants expressed in human mammary epithelial cells. (PubMed id 17133345)1 Moffa A.B. and Ethier S.P. (2007)
    10. Functional phylogeny relates LET-756 to fibroblast growth factor 9. (PubMed id 15199049)1 Popovici C....Roubin R. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8823 HGNC: 3672 AceView: FGF16 Ensembl:ENSG00000196468 euGenes: HUgn8823
    ECgene: FGF16 Kegg: 8823 H-InvDB: FGF16

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FGF16 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for FGF16 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FGF16 gene:
    Search GeneIP for patents involving FGF16

    GeneCards and IP:
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