External Ids for FGF16 Gene
Previous HGNC Symbols for FGF16 Gene
Previous GeneCards Identifiers for FGF16 Gene
This gene encodes a member of a family of proteins that are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene is expressed in cardiac cells and is required for proper heart development. Mutation in this gene was also observed in individuals with metacarpal 4-5 fusion. [provided by RefSeq, Mar 2014]
GeneCards Summary for FGF16 Gene
FGF16 (Fibroblast Growth Factor 16) is a Protein Coding gene. Diseases associated with FGF16 include syndactyly type 8 and metacarpal 4-5 fusion. Among its related pathways are PI3K-Akt signaling pathway and PI3K/AKT Signaling in Cancer. GO annotations related to this gene include growth factor activity and fibroblast growth factor receptor binding. An important paralog of this gene is FGF22.
UniProtKB/Swiss-Prot for FGF16 Gene
Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation, and is required for normal cardiomyocyte proliferation and heart development.