Aliases for FGF12 Gene
External Ids for FGF12 Gene
Previous Symbols for FGF12 Gene
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
GeneCards Summary for FGF12 Gene
FGF12 (Fibroblast Growth Factor 12) is a Protein Coding gene. Among its related pathways are PI3K-Akt signaling pathway and MAPK signaling pathway. GO annotations related to this gene include growth factor activity and ion channel binding. An important paralog of this gene is FGF22.
UniProtKB/Swiss-Prot for FGF12 Gene
Probably involved in nervous system development and function