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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FGF11 Gene

protein-coding   GIFtS: 52
GCID: GC17P007342

fibroblast growth factor 11
 Explore 4 diseases affiliated with
FGF11 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for FGF11    

Aliases
for FGF11 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Fibroblast Growth Factor 111 2     FHF-32 3
FHF31 2 3 5     FLJ160611
Fibroblast Growth Factor Homologous Factor 32 3     MGC1029531
FGF-112 3     MGC452691

External Ids:    HGNC: 36671   Entrez Gene: 22562   Ensembl: ENSG000001619587   OMIM: 6015145   UniProtKB: Q929143   

Export aliases for FGF11 gene to outside databases

Previous GC identifers: GC17M007769 GC17P008072 GC17P007285 GC17P007544 GC17P007545 GC17P007283


Summaries
for FGF11 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for FGF11:
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess
broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including
embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this gene
has not yet been determined. The expression pattern of the mouse homolog implies a role in nervous system development.
(provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: FGF11_HUMAN, Q92914
Function: Probably involved in nervous system development and function




Genomic Views
for FGF11 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010718.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FGF11 gene promoter:
         Pax-5   CUTL1   Tal-1beta   POU3F2   C/EBPalpha   GATA-1   GATA-2   PPAR-gamma2   ITF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): FGF11 promoter sequence
   Search SABiosciences Chromatin IP Primers for FGF11

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FGF11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.1   Ensembl cytogenetic band:  17p13.1   HGNC cytogenetic band: 17p13.1

FGF11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FGF11 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P007342:  view genomic region     (about GC identifiers)

Start:
 7,341,592 bp from pter      End:
 7,349,285 bp from pter
Size:
 7,694 bases      Orientation:
 plus strand

Proteins
for FGF11 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: FGF11_HUMAN, Q92914 (See protein sequence)
Recommended Name: Fibroblast growth factor 11  
Size: 225 amino acids; 25005 Da
Secondary accessions: Q2YDX8

Explore the universe of human proteins at neXtProt for FGF11: NX_Q92914

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q92914

    • FGF11 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_004103.1  
    ENSEMBL proteins: 
     ENSP00000459746   ENSP00000293829   ENSP00000468600   ENSP00000465134   ENSP00000460753  
     ENSP00000461397  

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    OriGene Protein Over-expression Lysate: FGF11
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for FGF11


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    Novus Biologicals FGF11 Antibodies
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    Uscn Antibodies for FGF11
    Search ThermoFisher Antibodies for FGF11

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    Uscn ELISAs and CLIAs for FGF11

    Protein Domains /
    Families
    for FGF11 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    FGF11 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR002348 IL1_HBGF
     IPR008996 Cytokine_IL1-like
     IPR002209 GF_heparin-bd

    Graphical View of Domain Structure for InterPro Entry Q92914

    ProtoNet protein and cluster: Q92914

    2 Blocks protein families:
    IPB002209 Heparin binding growth factor family signature
    IPB002348 IL1/HBGF family signature


    UniProtKB/Swiss-Prot: FGF11_HUMAN, Q92914
    Similarity: Belongs to the heparin-binding growth factors family


    Function
    for FGF11 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: FGF11_HUMAN, Q92914
    Function: Probably involved in nervous system development and function

         Genatlas biochemistry entry for FGF11:
    fibroblast growth homologous factor 11,expressed principally in the nervous system

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FGF11
    8/28 QIAGEN miScript miRNA Assays for microRNAs that regulate FGF11 (see all 28):
    hsa-miR-644 hsa-miR-328 hsa-miR-137 hsa-let-7d hsa-miR-330-5p hsa-miR-202 hsa-miR-331-3p hsa-let-7c
    SwitchGear 3'UTR luciferase reporter plasmid: FGF11 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FGF11 (see all 7)
    OriGene shRNA RFP: FGF11
    OriGene siRNA: FGF11
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FGF11

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for FGF11

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FGF11 (see all 4)
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    GenScript: all cDNA clones in your preferred vector: FGF11 (NM_004112)
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FGF11
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FGF11 

    Cell Line
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    Search LifeMap BioReagents cell lines for FGF11

    In Situ Assay
    Products:       
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008083growth factor activity IEA--


    FGF11 for ontologies           About GeneDecksing


    Animal Models:
         3 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Fgf11):
     behavior/neurological  integument  vision/eye 

    FGF11 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for FGF11 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/18 super-pathways (see all 18) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Apoptotic Pathways in Synovial Fibroblasts
    8/14 pathways (see all 14)
    		Apoptotic Pathways in Synovial Fibroblasts1.00
    		ERK5 Signaling0.61
    		p53 Mediated Apoptosis0.84
    		eIF2 Pathway0.60
    		Mitochondrial Apoptosis0.73
    		Rac1 Pathway0.58
    		Telomerase Components in Cell Signaling0.72
    		Nuclear Receptor Activation by Vitamin-A0.57
    2GPCR Pathway
    		GPCR Pathway1.00
    		Estrogen Pathway0.55
    		Ras Pathway0.62
    		Pancreatic Adenocarcinoma0.55
    		Breast Cancer Regulation by Stathmin10.58
    		Paxillin Interactions0.53
    		NFAT in Immune Response0.58
    		P2Y Receptor Signaling0.38
    3TGF-Beta Pathway
    		TGF-Beta Pathway1.00
    		JNK Pathway0.50
    		MAPK Family Pathway0.60
    		Regulation of eIF4 and p70S6K0.43
    		JAK-STAT Pathway0.57
    		SOCS Pathway0.29
    4Rho Family GTPases
    		Rho Family GTPases1.00
    		MAPK Signaling0.51
    		ERK Signaling0.61
    		ILK Signaling0.45
    		Molecular Mechanisms of Cancer0.51
    5Nanog in Mammalian ESC Pluripotency
    		Nanog in Mammalian ESC Pluripotency1.00
    		14-3-3 Induced Intracellular Signaling0.59
    		GSK3 Signaling0.61
    		eNOS Signaling0.48

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    5/59 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for FGF11 (see all 59)
        Nuclear Receptor Activation by Vitamin-A
    Paxillin Interactions
    Telomerase Components in Cell Signaling
    Mitochondrial Apoptosis
    Molecular Mechanisms of Cancer

    1 BioSystems Pathway for FGF11 
        Regulation of Actin Cytoskeleton


    4         Kegg Pathways  (Kegg details for FGF11):
        MAPK signaling pathway
    Regulation of actin cytoskeleton
    Pathways in cancer
    Melanoma


    FGF11 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FGF11

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    5/9 Interacting proteins for FGF11 (ENSP000002938294) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EGFRENSP000002754934STRING: ENSP00000275493
    FGFR1ENSP000003802804STRING: ENSP00000380280
    FGFR2ENSP000004102944STRING: ENSP00000410294
    FGFR3ENSP000002607954STRING: ENSP00000260795
    FGFR4ENSP000002924084STRING: ENSP00000292408
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction TAS8790420
    GO:0007267cell-cell signaling TAS8790420
    GO:0007399nervous system development TAS8790420


    FGF11 for ontologies           About GeneDecksing



    Drugs & Compounds
    for FGF11 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FGF11
    Search CenterWatch for drugs/clinical trials and news about FGF11 

    Transcripts
    for FGF11 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for FGF11 gene: 
    NM_004112.2  

    Unigene Cluster for FGF11:

    Fibroblast growth factor 11
    Hs.655193  [show with all ESTs]
    Unigene Representative Sequence: BC032502
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000575235(uc010cmh.1) ENST00000293829(uc010cmi.3 uc002ggz.3)
    ENST00000575331(uc010vtw.1 uc010vtx.2) ENST00000572907 ENST00000575398
    ENST00000575082 ENST00000576328

    miRNA
    Products:             		 OriGene 3'-UTR Clone: FGF11
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FGF11
    8/28 QIAGEN miScript miRNA Assays for microRNAs that regulate FGF11 (see all 28):
    hsa-miR-644 hsa-miR-328 hsa-miR-137 hsa-let-7d hsa-miR-330-5p hsa-miR-202 hsa-miR-331-3p hsa-let-7c
    SwitchGear 3'UTR luciferase reporter plasmid: FGF11 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FGF11 (see all 7)
    OriGene shRNA RFP: FGF11
    OriGene siRNA: FGF11
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FGF11
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FGF11 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FGF11
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FGF11
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FGF11

    Additional cDNA sequence: 

    AK293131.1 AK308477.1 AK308812.1 AK311269.1 AY049782.1 BC032502.1 BC037421.1 BC108265.1 
    U66199.1 Z70275.1 

    7 DOTS entries:

    DT.99973688  DT.312865  DT.100681637  DT.120899090  DT.97809630  DT.101962385  DT.91802269 

    24/92 AceView cDNA sequences (see all 92):

    BG697406 BM670363 T15934 AA601951 BM783551 BX115539 BC033882 BU736684 
    CR597907 F03722 NM_004112 CD514261 Z70275 BG472308 BM745211 BC032502 
    T16627 AL519512 BE222979 BM553166 BM740406 CA423112 BM677432 U66199 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for FGF11 (see all 8)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b · 8c
    SP1:              -     -     -     -                       -     -                                       
    SP2:                          -     -                       -     -                                       
    SP3:        -     -     -     -     -                       -                                             
    SP4:        -     -     -     -     -                       -     -                                       
    SP5:                                                        -                                             


    ECgene alternative splicing isoforms for FGF11

    Expression
    for FGF11 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FGF11 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AATACTTAGC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    FGF11 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    PureStem™ mesenchymal Progenitor SK11 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See FGF11 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FGF11

    SOURCE GeneReport for Unigene cluster: Hs.655193

    UniProtKB/Swiss-Prot: FGF11_HUMAN, Q92914
    Tissue specificity: Nervous system

        SABiosciences Expression via Pathway-Focused PCR Array including FGF11: 
              Growth Factors in human mouse rat

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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FGF11

    Orthologs
    for FGF11 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for FGF11 gene from 3/11 species (see all 11)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    lizard
    (Anolis carolinensis)    		 Reptilia FGF116
    		 --
    		 78(a)
    		 1 ↔ 1
    		 AAWZ02036351(6427-25727)
    zebrafish
    (Danio rerio)    		 Actinopterygii fgf11a1 fibroblast growth factor 11a 68.04(n)
    68.49(a)    		   497640  NM_001012380.1  NP_001012380.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta bnl6
    		 branchless
    		 5(a)
    		 1 → many
    		 3R(15619795-15662539)


    ENSEMBL Gene Tree for FGF11 (if available)
    TreeFam Gene Tree for FGF11 (if available) 

    Paralogs
    for FGF11 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FGF11 gene
    FGF122  FGF52  FGF202  FGF162  FGF42  FGF92  FGF62  FGF32  
    FGF72  FGF102  FGF222  FGF132  FGF142  
    16 SIMAP similar genes for FGF11 using alignment to 4 protein entries:     FGF11_HUMAN (see all proteins):
    FGF12    FGF13    FGF14    KGFLP1    FGF16    FGF9
    KGFLP2    FGF10    FGF7    PRED3    FGF20    FGF5
    FGF22    FGF1    FGF4    FGF8

    FGF11 for paralogs           About GeneDecksing



    Genomic Variants
    for FGF11 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/91 NCBI SNPs in FGF11 are shown (see all 91)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 17 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs341211921,2
    		C,--7340864(+) TGGGCG/AAGCGG 2 -- us2k1 ut314Minor allele frequency- A:0.14CSA WA NA EA 360
    rs98893031,2
    		C,--7341085(+) TTCTTT/GTGGTC 2 -- int1 us2k12Minor allele frequency- G:0.21CSA WA 120
    rs1388131841,2
    		--7341198(+) GCAGAG/TATATG 2 -- int1 us2k10--------
    rs1493496561,2
    		--7341493(+) TACCTC/TCAAGG 2 -- int1 us2k10--------
    rs1891899331,2
    		--7341645(+) CCGCTG/TCCGCC 1 -- us2k10--------
    rs1815733531,2
    		--7341760(+) GGCGTC/GGGGGG 1 -- us2k10--------
    rs1856750961,2
    		--7341894(+) GCAATC/GCCGGG 1 -- us2k10--------
    rs1153791261,2
    		F,--7341902(+) GGGGAG/AGACGA 1 -- us2k11Minor allele frequency- A:0.02WA 118
    rs41511201,2
    		C,F,A,H,--7342148(+) TCCAGT/ACAACT 1 -- us2k119Minor allele frequency- A:0.24NS EA WA NA CSA 1474
    rs1446467001,2
    		--7342156(+) ACTACC/GTGGTG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for FGF11 (7341592 - 7349285 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for FGF11: --

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    Disorders / Diseases
    for FGF11 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    FGF11 for disorders           About GeneDecksing

    OMIM gene information: 601514    OMIM disorders: --

    4 diseases for FGF11:    About MalaCards
    melanoma    breast cancer    adenocarcinoma    pancreatitis

    Human Genome Epidemiology (HuGE) Navigator: FGF11 (1 document)

    Export disorders for FGF11 gene to outside databases

    Publications
    for FGF11 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FGF11 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with FGF11)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development. (PubMed id 8790420)1, 2, 3 Smallwood P.M.... Nathans J. (1996)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Functional phylogeny relates LET-756 to fibroblast growth factor 9. (PubMed id 15199049)1 Popovici C....Roubin R. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    6. Physical map of 17p13 and the genes adjacent to p53. (PubMed id 10662545)1 Cousin P....Shaw P. (2000)
    7. Chromosomal mapping of two novel human FGF genes, FGF11 and FGF12. (PubMed id 9070933)1 Verdier A.S....Coulier F. (1997)

    External Searches for FGF11 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing FGF11 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 2256 HGNC: 3667 AceView: FGF11 Ensembl:ENSG00000161958 euGenes: HUgn2256
    ECgene: FGF11 Kegg: 2256 H-InvDB: FGF11

    Other Databases showing FGF11 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing FGF11 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FGF11 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for FGF11 Genetics and Cytogenetics in Oncology and Haematology
    NIEHS-SNPshttp://egp.gs.washington.edu/data/fgf11/

    Intellectual Property
    for FGF11 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for FGF11 gene:
    Search GeneIP for patents involving FGF11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
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    About This Section

     
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