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FGF10 Gene

protein-coding GIFtS: 63

GC05M044340

fibroblast growth factor 10
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
FGF-10 ^³

Descriptions
Keratinocyte growth factor 2 ^², ³
fibroblast growth factor 10 ^²
produced by fibroblasts of urinary bladder lamina propria ^²

External Ids
HGNC: 3666¹
Entrez Gene: 2255²
UniProtKB: O15520³
Ensembl: ENSG00000070193⁷

Search outside databases for aliases for FGF10 gene

Previous GC identifers: GC05M044614 GC05M045481 GC05M044305 GC05M044350

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for FGF10:

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF

family members possess broad mitogenic and cell survival activities, and are involved in a variety

of biological processes, including embryonic development, cell growth, morphogenesis, tissue

repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing

epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological

activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for

embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation

of lim bud formation. This gene is also implicated to be a primary factor in the process of wound

healing. [provided by RefSeq]

UniProtKB/Swiss-Prot: FGF10_HUMAN, O15520

Function: Could be a growth factor active in the process of wound healing. Acts as a mitogen in the

lung. May act in a manner similar to FGF-7

Gene Wiki entry for FGF10

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the FGF10 gene

Entrez Gene cytogenetic band: 5p13-p12 Ensembl cytogenetic band: 5p12 HGNC cytogenetic band: 5p13-p12

FGF10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 5 GeneLoc Exon Structure

GeneLoc location for GC05M044340: (about GC identifiers)

Start:	44,340,831 bp from pter
End:	44,424,623 bp from pter
Size:	83,793 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000005.8 NT_006576.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: FGF10_HUMAN, O15520 (See protein sequence)

Recommended Name: Fibroblast growth factor 10 precursor

Size: 208 amino acids; 23436 Da

Subunit: Interacts with FGFBP1

Subcellular location: Secreted (Potential)

PDB structures from and Proteopedia :

1NUN (3D)

Secondary accessions: Q6FHT6 Q96P59

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_004456.1

ENSEMBL proteins:

ENSP00000264664

Human Recombinant Proteins

	Invitrogen human recombinant proteins for FGF10
	Browse Purified and Recombinant Proteins at Millipore
	Sigma-Aldrich Proteins for FGF10
	R&D Systems Recombinant & Natural Proteins for FGF10 (FGF-10)
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (FGF10)
	Human Recombinant Proteins from Abnova (FGF10)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

4 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--
GO:0005615	extracellular space	TAS	9287324
GO:0005634	nucleus	IDA	11923311
GO:0009986	cell surface	NAS	11923311

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Antibodies for FGF10:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for FGF10
	R&D Systems Antibodies for FGF10 (FGF-10)
	Antibodies from Abcam (FGF10), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (FGF10)
	Novus Biologicals Antibodies for FGF10

Assays for FGF10:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry O15520

ProtoNet protein and cluster: O15520

2 Blocks protein families:

IPB002209 Heparin binding growth factor family signature

IPB002348 IL1/HBGF family signature

UniProtKB/Swiss-Prot: FGF10_HUMAN, O15520

Similarity: Belongs to the heparin-binding growth factors family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (FGF10)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (FGF10)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004465

Applied Biosystems Silencer® siRNAs for FGF10

Sigma-Aldrich siRNA and siRNA Panels for FGF10

Sigma-Aldrich shRNA for FGF10

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for FGF10
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_004465
Myc/DDK tagged cDNA clone in CMV expression vector: NM_004465
untagged cDNA clone in CMV expression vector: NM_004465

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_004465

UniProtKB/Swiss-Prot: FGF10_HUMAN, O15520

Function: Could be a growth factor active in the process of wound healing. Acts as a mitogen in the

lung. May act in a manner similar to FGF-7

Genatlas biochemistry entry for FGF10:

fibroblast growth factor 10,19kDa,essential regulator of lung and limb formation,involved in the

mesenchymal cells for the initiation and growth of the mouse limb bud,triggering FGF8 expression

in ectoderm and SHH expression in mesoderm

15/18 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Fgf10) (see all 18 ):

	adipose tissue	craniofacial	digestive/alimentary	embryogenesis
endocrine/exocrine gland	growth/size	hearing/vestibular/ear	homeostasis/metabolism	lethality-prenatal/perinatal
limbs/digits/tail	nervous system	renal/urinary system	reproductive system	respiratory system

5 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005104	fibroblast growth factor receptor binding	IDA	11923311
GO:0005515	protein binding	IPI	12591959
GO:0008083	growth factor activity	IDA	11923311
GO:0008201	heparin binding	IDA	11923311
GO:0042056	chemoattractant activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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4 Sigma-Aldrich "Your Favorite Gene" Pathways for FGF10 (Your Favorite Gene powered by Ingenuity)

Bladder Cancer Signaling
Actin Cytoskeleton Signaling
Clathrin-mediated Endocytosis
FGF Signaling

GeneDecks FGF10 for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for FGF10

5/60 Interacting proteins for FGF10 (O15520^{1, 2} ENSP00000264664³) via UniProtKB, MINT, and/or STRING (see all 60 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
FGFR2	P21802¹^,², ENSP00000333090³	EBI-1035684, EBI-1028658 MINT-24798 EBI-1035684, EBI-1028658 MINT-24798 STRING (score=.999)
FGFR2	P21802¹^,², ENSP00000333090³	EBI-1035684, EBI-1028658 MINT-24798 EBI-1035684, EBI-1028658 MINT-24798 STRING (score=.999)
FGFR2	P21802¹^,², ENSP00000333090³	EBI-1035684, EBI-1028658 MINT-24798 EBI-1035684, EBI-1028658 MINT-24798 STRING (score=.999)
SHH	ENSP00000297261³	STRING (score=.982)
FGFR3	ENSP00000354170³	STRING (score=.974)

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5/28 Gene Ontology (GO) biological process terms (links to tree view) (see all 28 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000060	protein import into nucleus, translocation	NAS	11923311
GO:0001759	induction of an organ	IEA	--
GO:0001974	blood vessel remodeling	IEA	--
GO:0006935	chemotaxis	IEA	--
GO:0006950	response to stress	NAS	11923311

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for FGF10
4 Novoseek chemical compound relationships for FGF10 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
bromodeoxyuridine	46.15	6	11286634 (1), 10503993 (1), 15690149 (1), 15137055 (1) (see all 5)
dextran sulfate sodium	36.81	2	10381813 (1)
heparan sulfate	30.89	1	14707131 (1)
tyrosine	18.83	5	11286634 (2), 17449030 (1), 16501574 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (FGF10)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (FGF10)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004465

Sigma-Aldrich siRNA and siRNA Panels for FGF10

Sigma-Aldrich shRNA for FGF10

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_004465

REFSEQ mRNAs for FGF10 gene:

NM_004465.1

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_004465

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_004465
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_004465
                                 untagged cDNA clone in CMV expression vector: NM_004465

Additional cDNA sequence:

AB002097.1 AF411527.1 AF508782.1 AK315314.1 BC069561.1 BC105021.1 BC105023.1 BC143772.1

CR541665.1 CR541688.1 U67918.1

3 DOTS entries:

DT.91752709 DT.120862189 DT.120862177

16 AceView cDNA sequences:

U67918 BX471703 AB002097 BX280011 BC069561 NM_004465 CA394078 BX484361

AF411527 CR541665 AF508782 BP380072 AL603565 BX955123 CR541688 BF983177

highest scoring ESTs for FGF10:

AB002097 AF411527 AF508782 AL603565 BC069561 BF983177 BX280011 U67918 BX484361 BX955123

Unigene Cluster for FGF10:

Fibroblast growth factor 10

Hs.664499 [show with all ESTs]

Unigene Representative Sequence: AK315314

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000264664

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

FGF10 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for FGF10

¹ / ² / ³

2 probe-sets matching FGF10 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
231762_at²^{, 3}	U133-B	1	0.91	1.00	--	--	NM_004465	0.60	1.00	0.82	1
231762_at²	U133Plus2	1	0.91	1.00	--	--	--	--	--	--	--

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: AACAAGAAGG

SOURCE GeneReport for Unigene cluster: Hs.664499

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for FGF10 gene from 5/8 species (see all 8 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	FGF10¹	--	fibroblast growth factor 10	95.65(n) 98.55(a)	612454 XM_850183.1 XP_855276.1
chimpanzee (Pan troglodytes)	FGF10¹	--	fibroblast growth factor 10	99.84(n) 100(a)	471553 XM_526931.2 XP_526931.2
cow (Bos taurus)	FGF10¹	--	fibroblast growth factor 10	94.66(n) 98.06(a)	326285 XM_001249706.1 XP_001249707.1
rat (Rattus norvegicus)	Fgf10¹	--	fibroblast growth factor 10	94.2(n) 100(a)	25443 NM_012951.1 NP_037083.1
mouse (Mus musculus)	Fgf10^{1, 5}	13 (75.00 cM)⁵	fibroblast growth factor 10^{1, 5}	92.43(n)¹ 94.69(a)¹	14165¹ NM_008002.3¹ NP_032028.1¹ AB064594⁵ AI527654⁵ (see all 17)

About this table Species with no ortholog for FGF10

ENSEMBL Gene Tree for FGF10

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for FGF10 gene

FGF7P2² FGF22² KGFLP2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/544 NCBI SNPs in FGF10 are shown (see all 544 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 197)

AB	SNP ID	Valid	Chr 5 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs2929855^1,2	C,F,H,O	44426121(+)	`TGAGCC/ACTTCA`	1	--	ng3¹		8	NS EU EA WA NA	700
	rs2973647^1,2	A,C,F,H	44425783(+)	`TTTCCC/TCCCTT`	1	--	ng3¹ trp³		5	NS EU EA WA	564
	rs16901836^1,2	C,F,H	44426383(+)	`TTGCTC/GGCAGA`	1	--	ng3¹		8	NS EU EA WA NA	676
--	rs17227508^1,2	C,F	44425225(-)	`GAAGGG/CGGTGG`	1	--	ng3¹ trp³		7	NS	626
	rs2973648^1,2	C,H	44426204(+)	`GAATAC/GCCTGC`	1	--	ng3¹		4	EU EA WA	420
--	rs17233910^1,2	C,F	44424574(-)	`CTGATG/AAGACA`	1	--	ng3¹		7	NS	638
	rs10078765^1,2	H	44426148(+)	`CTTCAA/TAGCAA`	1	--	ng3¹		4	EU EA WA	418
--	rs17233875^1,2	F	44426218(-)	`AAAAAGAA/-AACAG`	1	--	ng3¹		1	NS	132
--	rs17234646^1,2	F	44340477(-)	`GAATAC/TGAACT`	1	--	ng5¹		1	NS	166
--	rs17227522^1,2	F	44424835(-)	`CTGGTG/-ACCAA`	1	--	ng3¹		1	NS	154

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HapMap Linkage Disequilibrium images for FGF10 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 602115 disorders: 180920 149730

UniProtKB/Swiss-Prot: FGF10_HUMAN, O15520

Defects in FGF10 are the cause of autosomal dominant aplasia of lacrimal and salivary

glands (ALSG) [MIM:180920]. ALSG has variable expressivity, and affected individuals may have

aplasia or hypoplasia of the lacrimal, parotid, submandibular and sublingual glands and absence of

the lacrimal puncta. The disorder is characterized by irritable eyes, recurrent eye infections,

epiphora (constant tearing) and xerostomia (dryness of the mouth), which increases the risk of

dental erosion, dental caries, periodontal disease and oral infections

Defects in FGF10 are a cause of lacrimo-auriculo-dento-digital syndrome (LADDS)

[MIM:149730]; also known as Levy-Hollister syndrome. LADDS is a form of ectodermal dysplasia, a

heterogeneous group of disorders due to abnormal development of two or more ectodermal structures.

LADDS is an autosomal dominant syndrome characterized by aplastic/hypoplastic lacrimal and

salivary glands and ducts, cup-shaped ears, hearing loss, hypodontia and enamel hypoplasia, and

distal limb segments anomalies. In addition to these cardinal features, facial dysmorphism,

malformations of the kidney and respiratory system and abnormal genitalia have been reported.

Craniosynostosis and severe syndactyly are not observed

10/21 Novoseek disease relationships for FGF10 gene (see all 21 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
aplasia	57.08	9	19376597 (2), 16476029 (1), 15972105 (1), 17213838 (1)
pfeiffer syndrome	56.60	1	14613973 (1)
apert syndrome	55.15	1	14613973 (1)
craniosynostosis	50.46	1	15282208 (1)
hypoplasia	44.32	1	19376597 (1)
atresia	34.89	1	15234214 (1)
mucositis	33.87	5	11511852 (1), 15995938 (1), 15623608 (1)
hypospadias	20.14	4	17264867 (3), 15843416 (1)
bronchopulmonary dysplasia	19.43	5	17071719 (4)
colitis ulcerative	13.70	1	12786629 (1)

About this table

Human Gene Mutation Database: FGF10
Human Genome Epidemiology Navigator: FGF10 (3 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/171 PubMed articles for FGF10 gene (see all 171 ):

Structure and expression of human fibroblast growth factor-10. (PubMed id 9287324)^{1, 2, 3, 4} Emoto H....Itoh N. (1997)
Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors. (PubMed id 12591959)^{1, 3, 4} Yeh B.K.... Mohammadi M. (2003)
The fibroblast growth factor binding protein is a novel interaction partner of FGF-7, FGF-10 and FGF-22 and regulates FGF activity: implications for epithelial repair. (PubMed id 15806171)^{1, 3, 4} Beer H.-D....Werner S. (2005)
Mutations in different components of FGF signaling in LADD syndrome. (PubMed id 16501574)^{1, 3, 4} Rohmann E.... Wollnik B. (2006)
LADD syndrome is caused by FGF10 mutations. (PubMed id 16630169)^{3, 4} Milunsky J.M.... Everman D.B. (2006)
Mutations in the gene encoding fibroblast growth factor 10 are associated with aplasia of lacrimal and salivary glands. (PubMed id 15654336)^{3, 4} Entesarian M.... Dahl N. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
FGF-10 and its receptor exhibit bidirectional paracrine targeting to urothelial and smooth muscle cells in the lower urinary tract. (PubMed id 16597614)^{1, 3} Zhang D....Bassuk J.A. (2006)
FGF-10 is expressed at low levels in the human prostate. (PubMed id 10951499)^{1, 3} Ropiquet F....Ittmann M. (2000)
Investigation of FGF10 as a candidate gene in patients with anorectal malformations and exstrophy of the cloaca. (PubMed id 18587586)^{1, 3} Kruger V....Ludwig M. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 2255	HGNC: 3666	AceView: FGF10	Ensembl:ENSG00000070193	euGenes: HUgn2255
ECgene: FGF10	H-InvDB: FGF10

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for FGF10	Genetics and Cytogenetics in Oncology and Haematology
NIEHS-SNPs	http://egp.gs.washington.edu/data/fgf10/

Licensable Technologies for FGF10
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for FGF10:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for FGF10-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for FGF10		Antibodies for FGF10
	Explore super-pooled esiRNAs		Proteins for FGF10
	Lentivirus-delivered shRNAs for FGF10		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (FGF10)
	Antibodies (FGF10)
	Chimera RNAi (FGF10)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

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Search Tocris compounds for FGF10

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for FGF10

GeneCards Homepage - Last full update: 1 Jul 2009 Incremental update: 13 Oct 2009

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FGF10 Gene at Home site.
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FGF10 Gene

protein-coding GIFtS: 63

Aliases &
Descriptions
for FGF10

Summaries
for FGF10

Genomic Location
for FGF10

Proteins
for FGF10

Protein Domains/
Families
for FGF10

Gene Function
for FGF10

Pathways & Interactions
for FGF10

Drugs & Compounds
for FGF10

Transcripts
for FGF10

Expression
for FGF10

Orthologs
for FGF10

Paralogs
for FGF10

SNPs/Variants
for FGF10

Disorders & Mutations
for FGF10

Medical News
for FGF10

Publications
for FGF10

Search for FGF10

Genome Databases showing FGF10

Other Databases showing FGF10

Specialized Databases showing FGF10

Licensable Technologies
for FGF10

Services
for FGF10

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

FGF10 Gene

protein-coding GIFtS: 63

Aliases & Descriptionsfor FGF10

Summariesfor FGF10

Genomic Locationfor FGF10

Proteinsfor FGF10

Protein Domains/Familiesfor FGF10

Gene Functionfor FGF10

Pathways & Interactionsfor FGF10

Drugs & Compoundsfor FGF10

Transcriptsfor FGF10

Expression for FGF10

Orthologsfor FGF10

Paralogsfor FGF10

SNPs/Variantsfor FGF10

Disorders & Mutationsfor FGF10

Medical Newsfor FGF10

Publicationsfor FGF10

Search for FGF10

Genome Databases showing FGF10

Other Databases showing FGF10

Specialized Databases showing FGF10

Licensable Technologiesfor FGF10

Servicesfor FGF10

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for FGF10

Summaries
for FGF10

Genomic Location
for FGF10

Proteins
for FGF10

Protein Domains/
Families
for FGF10

Gene Function
for FGF10

Pathways & Interactions
for FGF10

Drugs & Compounds
for FGF10

Transcripts
for FGF10

Expression
for FGF10

Orthologs
for FGF10

Paralogs
for FGF10

SNPs/Variants
for FGF10

Disorders & Mutations
for FGF10

Medical News
for FGF10

Publications
for FGF10

Licensable Technologies
for FGF10

Services
for FGF10