Aliases for FGF1 Gene
External Ids for FGF1 Gene
Previous HGNC Symbols for FGF1 Gene
Previous GeneCards Identifiers for FGF1 Gene
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009]
GeneCards Summary for FGF1 Gene
FGF1 (Fibroblast Growth Factor 1) is a Protein Coding gene. Diseases associated with FGF1 include Familial Glomangioma and Blount's Disease. Among its related pathways are Glioma and p70S6K Signaling. GO annotations related to this gene include growth factor activity and Hsp70 protein binding. An important paralog of this gene is FGF2.
UniProtKB/Swiss-Prot for FGF1 Gene
Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.