Aliases for FGF1 Gene
External Ids for FGF1 Gene
Previous HGNC Symbols for FGF1 Gene
Previous GeneCards Identifiers for FGF1 Gene
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009]
GeneCards Summary for FGF1 Gene
FGF1 (Fibroblast Growth Factor 1 (Acidic)) is a Protein Coding gene. Diseases associated with FGF1 include familial glomangioma and blount's disease. Among its related pathways are PI3K-Akt signaling pathway and PI3K/AKT Signaling in Cancer. GO annotations related to this gene include growth factor activity and Hsp70 protein binding. An important paralog of this gene is FGF2.
UniProtKB/Swiss-Prot for FGF1 Gene
Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.