Aliases for FGD6 Gene
External Ids for FGD6 Gene
Previous GeneCards Identifiers for FGD6 Gene
GeneCards Summary for FGD6 Gene
FGD6 (FYVE, RhoGEF And PH Domain Containing 6) is a Protein Coding gene. Diseases associated with FGD6 include Aarskog-Scott Syndrome. Gene Ontology (GO) annotations related to this gene include guanyl-nucleotide exchange factor activity and small GTPase binding. An important paralog of this gene is FGD5.
UniProtKB/Swiss-Prot for FGD6 Gene
May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape (By similarity).