Aliases for FGD3 Gene
External Ids for FGD3 Gene
Previous GeneCards Identifiers for FGD3 Gene
GeneCards Summary for FGD3 Gene
FGD3 (FYVE, RhoGEF And PH Domain Containing 3) is a Protein Coding gene. Diseases associated with FGD3 include glucocorticoid deficiency 3 and aarskog-scott syndrome. Among its related pathways are Signaling by FGFR and Signaling by GPCR. GO annotations related to this gene include phospholipid binding and Rho guanyl-nucleotide exchange factor activity. An important paralog of this gene is FGD1.
UniProtKB/Swiss-Prot for FGD3 Gene
Promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape (By similarity).