FGD2 Gene
protein-coding GIFtS: 52
GCID: GC06P036973
|
|
FYVE, RhoGEF and PH domain containing 2(Previous names: FGD1 family, member 2 )
| |
Aliases
for FGD2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| FYVE, RhoGEF And PH Domain Containing 21 2 | | ZFYVE41 2 3 | | FGD1 Family, Member 21 2 | | Zinc Finger FYVE Domain-Containing Protein 42 3 | | FLJ00276 Protein2 | | FYVE, RhoGEF And PH Domain-Containing Protein 22 |
Export aliases for FGD2 gene to outside databasesPrevious GC identifers: GC06U990176 GC06P036970 GC06P037020 GC06P037081 GC06P036691 |
Summaries
for FGD2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: FGD2_HUMAN, Q7Z6J4Function: Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for freeGTP. Activates JNK1 via CDC42 but not RAC1. Binds to phosphatidylinositol 4,5-bisphosphate, phosphatidylinositol3,4,5-trisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate andphosphatidylinositol 3-monophosphate (By similarity)
Gene Wiki entry for FGD2
|
Genomic Views
for FGD2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FGD2 gene promoter:
HOXA3 Pax-5 AML1a NRSF form 1 Pax-2 Pax-2a NRSF form 2 CREB deltaCREB Ik-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for FGD2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FGD2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p21.2 Ensembl cytogenetic band: 6p21.2 HGNC cytogenetic band: 6p21.2FGD2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P036973: view genomic region
(about GC identifiers)
Start:
|
36,973,422 bp from pter |
End:
|
36,996,846 bp from pter |
Size:
|
23,425 bases |
Orientation:
|
plus strand |
|
Proteins
for FGD2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: FGD2_HUMAN, Q7Z6J4 (See
protein sequence)Recommended Name: FYVE, RhoGEF and PH domain-containing protein 2 Size: 655 amino acids; 74892 Da
Subcellular location: Cytoplasm, cytoskeleton (Probable). Cytoplasm (By similarity). Nucleus (By similarity). Earlyendosome (By similarity). Early endosome membrane (By similarity). Cell projection, ruffle membrane (By similarity).Note=Recruitment to the endosome and ruffle membrane requires the presence of phosphoinositides (By similarity)
Sequence caution: Sequence=BAB15746.1; Type=Erroneous initiation; Sequence=BAC85129.1; Type=Erroneous initiation;Note=Translation N-terminally shortened; Sequence=BAC85129.1; Type=Frameshift; Positions=460; Sequence=CAI20471.1;Type=Erroneous gene model prediction;
Secondary accessions: Q5T8I1 Q6P6A8 Q6ZNL5 Q8IZ32 Q8N868 Q9H7M2Alternative splicing: 4 isoforms: Q7Z6J4-1 Q7Z6J4-2 Q7Z6J4-4 Q7Z6J4-5 (May be due to an intron retention. No experimental confirmation available)Explore the universe of human proteins at neXtProt for FGD2: NX_Q7Z6J4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q7Z6J4
FGD2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_775829.2
ENSEMBL proteins: ENSP00000274963 ENSP00000362635 ENSP00000419657 Reactome Protein details: Q7Z6J4
Human Recombinant Protein Products:
Gene Ontology (GO): 5/9 cellular component terms (GO ID links to tree view) (see all 9): About this table
FGD2 for ontologies About GeneDecksing
FGD2 Antibody Products:
Assay Products for FGD2: |
Protein
Domains /
Families
for FGD2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FGD2 for domains About GeneDecksing
5/7 InterPro domains/families (see all 7):Graphical View of Domain Structure for InterPro Entry Q7Z6J4ProtoNet protein and cluster: Q7Z6J4 3 Blocks protein families: IPB000219 DH domain IPB000306 Zn-finger IPB001849 Pleckstrin-like
UniProtKB/Swiss-Prot: FGD2_HUMAN, Q7Z6J4Domain: The FYVE-type zinc-finger is necessary for early endosome localization. Recruitment to endosomal membranes viathis domain requires the presence of phosphatidylinositol 3-phosphate or other phosphatidylinositides (By similarity)Domain: The PH domain is necessary for localization to the ruffle membrane. Recruitment to ruffle membrane occursthrough binding of phosphoinositides by the PH domain. This domain also contributes to the lipid-binding properties ofthe protein (By similarity)Domain: The DH domain is necessary for its ability to activate JNK1 via CDC42 (By similarity)Similarity: Contains 1 DH (DBL-homology) domainSimilarity: Contains 1 FYVE-type zinc fingerSimilarity: Contains 2 PH domains |
Function
for FGD2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: FGD2_HUMAN, Q7Z6J4Function: Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for freeGTP. Activates JNK1 via CDC42 but not RAC1. Binds to phosphatidylinositol 4,5-bisphosphate, phosphatidylinositol3,4,5-trisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate andphosphatidylinositol 3-monophosphate (By similarity) Genatlas biochemistry entry for FGD2:Rho GEF (guanine nucleotide exchange factor) 2,homolog of FGD1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FGD2 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FGD2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FGD2 (NM_173558) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FGD2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FGD2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FGD2 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005085 | guanyl-nucleotide exchange factor activity |
ISS | -- | | GO:0005089 | Rho guanyl-nucleotide exchange factor activity |
IEA | -- | | GO:0005543 | phospholipid binding |
IEA | -- | | GO:0031267 | small GTPase binding |
ISS | -- | | GO:0046872 | metal ion binding |
IEA | -- |
FGD2 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Fgd2tm1Bgh for FGD2
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Fgd2):
FGD2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for FGD2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cell death signalling via NRAGE, NRIF and NADE | | | 2 | Signaling by GPCR | | | 3 | Signaling by FGFR | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/10 
Reactome Pathways for FGD2 (see all 10)
FGD2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FGD2
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for FGD2 (Q7Z6J43 ENSP000002749634) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006915 | apoptotic process |
TAS | -- | | GO:0007010 | cytoskeleton organization |
ISS | -- | | GO:0007264 | small GTPase mediated signal transduction |
TAS | -- | | GO:0008360 | regulation of cell shape |
ISS | -- | | GO:0030036 | actin cytoskeleton organization |
ISS | -- |
FGD2 for ontologies About GeneDecksing
|
Drugs & Compounds
for FGD2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FGD2
1 HMDB Compound for FGD2 About this table
Search CenterWatch for drugs/clinical trials and news about FGD2
|
Transcripts
for FGD2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FGD2 gene: NM_173558.3 Unigene Cluster for FGD2: FYVE, RhoGEF and PH domain containing 2 Hs.509664 [show with all ESTs]Unigene Representative Sequence: BC02364511 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000489356(uc003onf.3) ENST00000274963(uc010jwp.1 uc003ong.2 uc011dtv.1)
ENST00000373535 ENST00000497659 ENST00000459781 ENST00000487975(uc011dtu.1)
ENST00000464083 ENST00000494343(uc003oni.1) ENST00000470273 ENST00000493635
ENST00000487920(uc003onj.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FGD2 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FGD2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FGD2 (NM_173558) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FGD2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FGD2 |
Additional cDNA sequence: AK290419.1 AK300964.1 AK301156.1 BC023645.2 BC053655.1 BX648164.1 6 DOTS entries: DT.91748862 DT.100018798 DT.100030953 DT.100675094 DT.100774684 DT.40311561 24/49 AceView cDNA sequences (see all 49): CD366726 BC062363 BX105773 BQ708371 AA749152 AX747694 BF909099 AA825628 BC053655 AK131079 AK092732 AK024456 BG686784 AI524250 BX115167 CB266766 AK097981 AI568774 CA392949 BX510116 AK098248 BM922781 BQ711182 BQ705924
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for FGD2 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b |
|---|
|
| SP1: | | | | | | | | | | | | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for FGD2
|
Expression
for FGD2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FGD2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See FGD2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FGD2
SOURCE GeneReport for Unigene cluster: Hs.509664
SABiosciences Custom PCR Arrays for FGD2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FGD2
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FGD2 |
Orthologs
for FGD2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for FGD2 gene from 3/17 species (see all 17) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
FGD26 |
-- |
69(a) |
1 ↔ 1 |
GL343382.1(9934-23121) |
honey bee
(Apis mellifera) |
Insecta |
-- |
-- |
24(a) |
1 → many |
Group2.1(18879-21756) |
worm
(Caenorhabditis elegans) |
Secernentea |
exc-56 |
EXCretory canal abnormal family member (exc-5) |
19(a) |
1 → many |
IV(8799076-8804844) |
ENSEMBL Gene Tree for FGD2 (if available)
TreeFam Gene Tree for FGD2 (if available) |
Paralogs
for FGD2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FGD2 gene
- FGD32 PLEKHF22 FGD52 PLEKHF12 FGD62 FGD42 FGD12
5 SIMAP similar genes for FGD2 using alignment to 3 protein entries: FGD2_HUMAN (see all proteins):FGD4 FGD1 FLJ00004 FGD3 FGD6
FGD2 for paralogs About GeneDecksing
|
Genomic Variants
for FGD2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FGD2 (36973422 - 36996846 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for FGD2
1 CNV: 51907
1 Indel: 51908 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FGD2 |
|
Disorders
/ Diseases
for FGD2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
FGD2 for disorders About GeneDecksing
OMIM gene information: 605091
OMIM disorders: --
2  diseases for FGD2: About MalaCardsaarskog-scott syndrome scott syndrome
Export disorders for FGD2 gene to outside databases
|
Publications
for FGD2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FGD2 gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with FGD2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Isolation, characterization, and mapping of the mouse and human Fgd2 genes, faciogenital dysplasia (FGD1; Aarskog syndrome) gene homologues. (PubMed id 10458911)1, 3, 9 Pasteris N.G. and Gorski J.L. (1999)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
- Characterization of long cDNA clones from human adult spleen. (PubMed id 11214971)1, 2 Hattori A.... Ohara O. (2000)
- FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles. (PubMed id 18838382)1 Huber C....Gavin A.L. (2008)
- Mutations in FGD4 encoding the Rho GDP/GTP exchange factor FRABIN cause autosomal recessive Charcot-Marie-Tooth type 4H. (PubMed id 17564959)1 Delague V.... Levy N. (2007)
- Large-scale analysis of the human ubiquitin-related p roteome. (PubMed id 16196087)1 Matsumoto M....Nakayama K.I. (2005)
- Ten years on: mediation of cell death by the common n eurotrophin receptor p75(NTR). (PubMed id 12787561)1 Rabizadeh S. and Bredesen D.E. (2003)
- NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway. (PubMed id 12376548)1 Salehi A.H....Barker P.A. (2002)
|
External Searches for FGD2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FGD2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FGD2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FGD2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FGD2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FGD2 gene:
Search GeneIP for patents involving FGD2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FGD2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FGD2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FGD2 | | | OriGene Protein Over-expression Lysate for FGD2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for FGD2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FGD2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FGD2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for FGD2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FGD2 | | OriGene Custom Protein Services for FGD2 | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FGD2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FGD2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FGD2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FGD2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FGD2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FGD2 |
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| | | | Search Tocris compounds for FGD2 |
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 | | | FGD2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FGD2 |
|  |  |  | | | | Search ThermoFisher Antibodies for FGD2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FGD2 |
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