Aliases for FGD1 Gene
Aliases for FGD1 Gene
External Ids for FGD1 Gene
- HGNC: 3663
- Entrez Gene: 2245
- Ensembl: ENSG00000102302
- OMIM: 300546
- UniProtKB: P98174
Previous HGNC Symbols for FGD1 Gene
- FGDY
Previous GeneCards Identifiers for FGD1 Gene
- GC0XM051323
- GC0XM052410
- GC0XM053077
- GC0XM053438
- GC0XM054354
- GC0XM051522
Summaries for FGD1 Gene
-
This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of the faciogenital dysplasia in Aarskog-Scott syndrome and a syndromatic form of X-linked cognitive disability. [provided by RefSeq, Jul 2017]
GeneCards Summary for FGD1 Gene
FGD1 (FYVE, RhoGEF And PH Domain Containing 1) is a Protein Coding gene. Diseases associated with FGD1 include Aarskog-Scott Syndrome and Scott Syndrome. Among its related pathways are p75 NTR receptor-mediated signalling and Actin Nucleation by ARP-WASP Complex. Gene Ontology (GO) annotations related to this gene include guanyl-nucleotide exchange factor activity and small GTPase binding. An important paralog of this gene is FGD4.
UniProtKB/Swiss-Prot for FGD1 Gene
-
Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape.
Additional gene information for FGD1 Gene
- Monarch Initiative
- Search for FGD1 at DataMed
- Search for FGD1 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FGD1 Gene
Genomics for FGD1 Gene
GeneHancer (GH) Regulatory Elements for FGD1 Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH0XI054494 | Promoter/Enhancer | 1.7 | EPDnew Ensembl ENCODE | 550.8 | +0.6 | 563 | 3.1 | ZSCAN5A BCOR ZNF76 ZMYM3 ZNF384 ZNF335 ZFHX2 EGR1 POLR2A ZBTB48 | FGD1 PIR39642 GC0XM054327 | |
GH0XI053681 | Promoter/Enhancer | 2.1 | EPDnew Ensembl ENCODE | 11.1 | +811.8 | 811767 | 6 | HDGF PKNOX1 CLOCK SMAD1 MLX ARNT ARID4B SIN3A DMAP1 ZNF2 | HUWE1 FAM156B PHF8 KANTR ACTG1P10 ENSG00000233250 TSPYL2 KDM5C FGD1 HSD17B10 | |
GH0XI054042 | Promoter/Enhancer | 2.1 | EPDnew Ensembl ENCODE | 11.1 | +451.8 | 451817 | 3.9 | PKNOX1 CLOCK FOXA2 ARNT NEUROD1 SIN3A FEZF1 DMAP1 ZNF2 YY1 | PHF8 KDM5C ACTG1P10 SMC1A KANTR ENSG00000233250 TSPYL2 APEX2 GPR173 MAGED2 | |
GH0XI054539 | Enhancer | 0.3 | ENCODE | 12.7 | -44.1 | -44100 | 1 | CTCF | FGD1 GNL3L GC0XM054327 | |
GH0XI054474 | Enhancer | 0.2 | ENCODE | 14.6 | +21.5 | 21500 | 0.9 | FGD1 TSR2 GNL3L PIR39642 GC0XM054327 |
- Top Transcription factor binding sites by QIAGEN in the FGD1 gene promoter:
Regulatory Element Products
Genomic Locations for FGD1 Gene
- chrX:54,445,454-54,496,166
- (GRCh38/hg38)
- Size:
- 50,713 bases
- Orientation:
- Minus strand
- chrX:54,471,887-54,522,599
- (GRCh37/hg19)
Genomic View for FGD1 Gene
- Cytogenetic band:
-
- Xp11.22 by Ensembl
- Xp11.22 by Entrez Gene
- Xp11.22 by HGNC


RefSeq DNA sequence for FGD1 Gene
Proteins for FGD1 Gene
-
Protein details for FGD1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P98174-FGD1_HUMAN
- Recommended name:
- FYVE, RhoGEF and PH domain-containing protein 1
- Protein Accession:
- P98174
- Q5H999
- Q8N4D9
Protein attributes for FGD1 Gene
- Size:
- 961 amino acids
- Molecular mass:
- 106561 Da
- Quaternary structure:
-
- Interacts with DBNL/ABP1 and CTTN. May interact with CCPG1 (By similarity). Binds CDC42.
Protein Expression for FGD1 Gene
Post-translational modifications for FGD1 Gene
Other Protein References for FGD1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
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-
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Protein Products
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-
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Assay Products
- antibodies-online: Search results for available FGD1 related products ranked by validation data
No data available for DME Specific Peptides for FGD1 Gene
Domains & Families for FGD1 Gene
Gene Families for FGD1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Disease related genes
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for FGD1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for FGD1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P98174- Domain:
-
- The DH domain is involved in interaction with CCPG1.
Function for FGD1 Gene
Molecular function for FGD1 Gene
- GENATLAS Biochemistry:
- Rho/Rac,CDC42Hs specific (guanine nucleotide exchange factor) 1,involved in signal transduction and mammalian morphogenesis
- UniProtKB/Swiss-Prot Function:
- Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005085 | guanyl-nucleotide exchange factor activity | TAS | -- |
GO:0005089 | Rho guanyl-nucleotide exchange factor activity | TAS | -- |
GO:0031267 | small GTPase binding | IDA | 8969170 |
GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for FGD1 Gene
- GenomeRNAi human phenotypes for FGD1:
-
- Increased viability
- Increased vaccinia virus (VACV) infection
- Increased gamma-H2AX phosphorylation
- Synthetic lethal with Ras
- Mildly decreased CFP-tsO45G cell surface transport
- Decreased shRNA abundance (Z-score < -2)
- Decreased NF-kappaB reporter expression
- Decreased IL-8 secretion
- Decreased shRNA abundance
- Synthetic lethal with vaccinia virus (VACV) infection
- Increased shRNA abundance (Z-score > 2)
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-
-
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-
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miRNA for FGD1 Gene
- miRTarBase miRNAs that target FGD1
-
- hsa-mir-4640-3p (MIRT610377)
- hsa-mir-2355-3p (MIRT610378)
- hsa-mir-676-3p (MIRT610379)
- hsa-mir-6749-3p (MIRT610380)
- hsa-mir-6852-3p (MIRT610381)
- hsa-mir-3909 (MIRT610382)
- hsa-mir-7151-5p (MIRT610383)
- hsa-mir-4446-5p (MIRT613876)
- hsa-mir-5006-3p (MIRT613877)
- hsa-mir-4755-5p (MIRT613878)
- hsa-mir-670-5p (MIRT613879)
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-
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- Mammalian expression: PiggyBac
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- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
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No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Animal Models , Transcription Factor Targets and HOMER Transcription for FGD1 Gene
Localization for FGD1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for FGD1 Gene
- Cytoplasm. Cell projection, lamellipodium. Cell projection, ruffle. Cytoplasm, cytoskeleton. Note=Associated with membrane ruffles and lamellipodia. {ECO:0000250}.
- Cytosol (2)
- Plasma membrane (2)
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0001726 | ruffle | ISS | -- |
GO:0005737 | cytoplasm | ISS | -- |
GO:0005794 | Golgi apparatus | IEA,ISS | -- |
GO:0005829 | cytosol | TAS | -- |
GO:0005856 | cytoskeleton | IEA | -- |
Pathways & Interactions for FGD1 Gene
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | p75 NTR receptor-mediated signalling |
.36
|
|
2 | Signaling by GPCR | ||
3 | Regulation of actin cytoskeleton | ||
4 | Actin Nucleation by ARP-WASP Complex |
.41
|
|
5 | Signaling by Rho GTPases |
Pathways by source for FGD1 Gene
2 BioSystems pathways for FGD1 Gene
10 Reactome pathways for FGD1 Gene
1 KEGG pathway for FGD1 Gene
1 GeneGo (Thomson Reuters) pathway for FGD1 Gene
1 Qiagen pathway for FGD1 Gene
Interacting Proteins for FGD1 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0007010 | cytoskeleton organization | ISS,IEA | -- |
GO:0007165 | signal transduction | TAS | 8969170 |
GO:0007186 | G-protein coupled receptor signaling pathway | TAS | -- |
GO:0007275 | multicellular organism development | TAS | 8969170 |
GO:0008360 | regulation of cell shape | ISS,IEA | -- |
No data available for SIGNOR curated interactions for FGD1 Gene
Drugs & Compounds for FGD1 Gene
Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
---|---|---|---|---|---|---|
Guanosine triphosphate | Experimental | Pharma | 0 |
Transcripts for FGD1 Gene
mRNA/cDNA for FGD1 Gene
- (1) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (75) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FGD1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for FGD1
- genomics-online: gRNA clones - Search results for available FGD1 gene related products
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-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for FGD1
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miRNA Products
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Inhibitory RNA Products
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-
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Clone Products
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- VectorBuilder custom plasmid, inducible vectors for FGD1
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available FGD1 gene related products
- orf clones - Search results for available FGD1 gene related products
- Applied Biological Materials Clones for FGD1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for FGD1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for FGD1 Gene
NURSA nuclear receptor signaling pathways regulating expression of FGD1 Gene:
FGD1SOURCE GeneReport for Unigene cluster for FGD1 Gene:
Hs.709201mRNA Expression by UniProt/SwissProt for FGD1 Gene:
P98174-FGD1_HUMANEvidence on tissue expression from TISSUES for FGD1 Gene
- Nervous system(4.2)
Phenotype-based relationships between genes and organs from Gene ORGANizer for FGD1 Gene
- ectoderm
- endoderm
- mesoderm
- cardiovascular
- digestive
- immune
- integumentary
- lymphatic
- nervous
- reproductive
- respiratory
- skeletal muscle
- skeleton
- urinary
- brain
- cheek
- chin
- cranial nerve
- ear
- eye
- eyelid
- face
- forehead
- head
- jaw
- lip
- mandible
- maxilla
- mouth
- neck
- nose
- outer ear
- salivary gland
- scalp
- skull
- tooth
- breast
- chest wall
- clavicle
- esophagus
- lung
- rib
- rib cage
- scapula
- sternum
- abdominal wall
- intestine
- kidney
- large intestine
- liver
- spleen
- anus
- fallopian tube
- ovary
- pelvis
- penis
- prostate
- rectum
- testicle
- uterus
- vagina
- vas deferens
- vulva
- ankle
- arm
- digit
- elbow
- femur
- fibula
- finger
- foot
- forearm
- hand
- hip
- humerus
- knee
- lower limb
- nail
- radius
- shin
- shoulder
- thigh
- tibia
- toe
- ulna
- upper limb
- wrist
- blood
- blood vessel
- coagulation system
- hair
- lymph node
- lymph vessel
- peripheral nervous system
- red blood cell
- skin
- spinal column
- vertebrae
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-
OriGene qPCR primer pairs for FGD1
-
OriGene qPCR primer pairs and template standards for FGD1
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No data available for mRNA differential expression in normal tissues for FGD1 Gene
Orthologs for FGD1 Gene
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | FGD1 34 33 |
|
OneToOne | |
dog (Canis familiaris) |
Mammalia | FGD1 34 33 |
|
OneToOne | |
cow (Bos Taurus) |
Mammalia | FGD1 34 33 |
|
OneToOne | |
rat (Rattus norvegicus) |
Mammalia | Fgd1 33 |
|
||
mouse (Mus musculus) |
Mammalia | Fgd1 16 34 33 |
|
||
oppossum (Monodelphis domestica) |
Mammalia | FGD1 34 |
|
OneToOne | |
platypus (Ornithorhynchus anatinus) |
Mammalia | FGD1 34 |
|
OneToOne | |
lizard (Anolis carolinensis) |
Reptilia | FGD1 34 |
|
OneToOne | |
tropical clawed frog (Silurana tropicalis) |
Amphibia | fgd1 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | fgd1 34 33 |
|
OneToOne | |
fruit fly (Drosophila melanogaster) |
Insecta | RhoGEF4 34 |
|
ManyToMany | |
worm (Caenorhabditis elegans) |
Secernentea | exc-5 35 34 |
|
||
sea squirt (Ciona savignyi) |
Ascidiacea | CSA.6211 34 |
|
OneToMany |
- Species where no ortholog for FGD1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for FGD1 Gene
Variants for FGD1 Gene
SNP ID | Clin | Chr 0X pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs137853264 | pathogenic, Aarskog syndrome, Aarskog-Scott syndrome (AAS) [MIM:305400] | 54,465,522(-) | C/T | coding_sequence_variant, missense_variant | |
rs137853265 | pathogenic, Aarskog syndrome | 54,467,901(-) | C/T | coding_sequence_variant, missense_variant | |
rs137853266 | pathogenic, Aarskog syndrome | 54,467,796(-) | C/A | coding_sequence_variant, missense_variant | |
rs137853267 | pathogenic, Aarskog syndrome | 54,465,797(-) | T/C | coding_sequence_variant, missense_variant | |
rs138723423 | benign, likely-benign, not specified, not provided | 54,470,441(-) | C/T | coding_sequence_variant, missense_variant |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2740175 | CNV | deletion | 23290073 |
nsv435891 | CNV | deletion | 17901297 |
Additional Variant Information for FGD1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FGD1 Gene
Disorders for FGD1 Gene

(7) MalaCards diseases for FGD1 Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards
Disorder | Aliases | PubMed IDs |
---|---|---|
aarskog-scott syndrome |
|
|
scott syndrome |
|
|
crane-heise syndrome |
|
|
unilateral focal polymicrogyria |
|
|
global developmental delay, absent or hypoplastic corpus callosum, and dysmorphic facies |
|
UniProtKB/Swiss-Prot
FGD1_HUMAN- Aarskog-Scott syndrome (AAS) [MIM:305400]: A rare multisystemic disorder characterized by disproportionately short stature, and by facial, skeletal and urogenital anomalies. Some patients manifest mental retardation, attention deficit disorder and hyperactivity. {ECO:0000269 PubMed:10930571, ECO:0000269 PubMed:11093277, ECO:0000269 PubMed:14560308}. Note=The disease is caused by mutations affecting the gene represented in this entry.
- Note=Defects in FGD1 are found in a patient with non-syndromal X-linked mental retardation. {ECO:0000269 PubMed:11940089}.
Genatlas disease for FGD1 Gene
Additional Disease Information for FGD1
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Publications for FGD1 Gene
- Phenotypic and molecular characterisation of the Aarskog-Scott syndrome: a survey of the clinical variability in light of FGD1 mutation analysis in 46 patients. (PMID: 14560308) Orrico A … Sorrentino V (European journal of human genetics : EJHG 2004) 3 4 22 44 58
- Non-syndromic X-linked mental retardation associated with a missense mutation (P312L) in the FGD1 gene. (PMID: 11940089) Lebel RR … Schwartz CE (Clinical genetics 2002) 3 4 22 44 58
- Two novel mutations confirm FGD1 is responsible for the Aarskog syndrome. (PMID: 11093277) Schwartz CE … Neri G (European journal of human genetics : EJHG 2000) 3 4 22 58
- A mutation in the pleckstrin homology (PH) domain of the FGD1 gene in an Italian family with faciogenital dysplasia (Aarskog-Scott syndrome). (PMID: 10930571) Orrico A … Sorrentino V (FEBS letters 2000) 3 4 22 58
- Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: a putative Rho/Rac guanine nucleotide exchange factor. (PMID: 7954831) Pasteris NG … Gorski JL (Cell 1994) 3 4 22 58
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 13 available FGD1 Antibodies ranked by validation data
- Compare Top FGD1 Antibodies
- antibodies-online: Search results for available FGD1 related products ranked by validation data
- antibodies-online: Search results for 3 available FGD1 Proteins ranked by validation data
- Compare Top FGD1 Proteins
- GeneTex FGD1 antibody for FGD1
- Search GeneTex for Proteins for FGD1
- ViGene Biosciences adenoviral particle packaged cDNA for FGD1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for FGD1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for FGD1 gene
- Search ViGene Biosciences for FGD1
- Santa Cruz Biotechnology (SCBT) Antibodies for FGD1
- Search Santa Cruz Biotechnology (SCBT) for FGD1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for FGD1
- Horizon Cell Lines for FGD1
- genomics-online: cdna clones - Search results for available FGD1 gene related products
- orf clones - Search results for available FGD1 gene related products
- genomics-online: gRNA clones - Search results for available FGD1 gene related products
- genomics-online: primer clones - Search results for available FGD1 gene related products
- genomics-online: shRNA clones - Search results for available FGD1 gene related products
Sources for FGD1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew