Aliases for FGD1 Gene
Aliases for FGD1 Gene
External Ids for FGD1 Gene
- HGNC: 3663
- Entrez Gene: 2245
- Ensembl: ENSG00000102302
- OMIM: 300546
- UniProtKB: P98174
Previous HGNC Symbols for FGD1 Gene
- FGDY
Previous GeneCards Identifiers for FGD1 Gene
- GC0XM051323
- GC0XM052410
- GC0XM053077
- GC0XM053438
- GC0XM054354
- GC0XM051522
Summaries for FGD1 Gene
-
This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.[provided by RefSeq, Mar 2011]
GeneCards Summary for FGD1 Gene
FGD1 (FYVE, RhoGEF And PH Domain Containing 1) is a Protein Coding gene. Diseases associated with FGD1 include Aarskog-Scott Syndrome and Fgd1-Related X-Linked Mental Retardation. Among its related pathways are Signaling by GPCR and G-protein signaling_Regulation of CDC42 activity. GO annotations related to this gene include guanyl-nucleotide exchange factor activity and small GTPase binding. An important paralog of this gene is FGD4.
UniProtKB/Swiss-Prot for FGD1 Gene
-
Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FGD1 Gene
Genomics for FGD1 Gene
Regulatory Elements for FGD1 Gene
Enhancers for FGD1 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH0XF054042 | 1.1 | ENCODE | 11.1 | +451.8 | 451775 | 3.8 | PKNOX1 CREB3L1 SIN3A FEZF1 DMAP1 ZNF2 YY1 ZNF143 FOS KLF13 | KDM5C KANTR RPL7AP71 RPSAP62 APEX2 ACTG1P10 ENSG00000270189 FGD1 ENSG00000227329 GPR173 |
| GH0XF053681 | 1.1 | ENCODE | 11.1 | +811.8 | 811795 | 5.9 | HDGF PKNOX1 CREB3L1 MLX ARID4B SIN3A DMAP1 ZNF2 YY1 DEK | ACTG1P10 ENSG00000233250 KANTR KDM5C ENSG00000227329 ENSG00000270189 FGD1 HSD17B10 GPR173 KDM5C-IT1 |
| GH0XF054474 | 0.4 | ENCODE | 14.5 | +21.5 | 21500 | 0.9 | CTCF | FGD1 TSR2 GNL3L PIR39642 |
| GH0XF054539 | 0.4 | ENCODE | 12.6 | -44.1 | -44100 | 1.0 | CTCF | FGD1 GNL3L GC0XM054327 |
| GH0XF054491 | 0.8 | Ensembl ENCODE | 0.8 | +3.6 | 3576 | 1.2 | ZNF121 KLF1 MYC ZIC2 ZXDB ZKSCAN1 | GNL3L FGD1 PIR39642 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FGD1 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the FGD1 gene promoter:
Regulatory Element Products
Genomic Location for FGD1 Gene
- Chromosome:
- X
- Start:
- 54,445,454 bp from pter
- End:
- 54,496,166 bp from pter
- Size:
- 50,713 bases
- Orientation:
- Minus strand
Genomic View for FGD1 Gene
Genes around FGD1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- Xp11.22 by Ensembl
- Xp11.22 by Entrez Gene
- Xp11.22 by HGNC
FGD1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FGD1 Gene
Proteins for FGD1 Gene
-
Protein details for FGD1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P98174-FGD1_HUMAN
- Recommended name:
- FYVE, RhoGEF and PH domain-containing protein 1
- Protein Accession:
- P98174
- Q5H999
- Q8N4D9
Protein attributes for FGD1 Gene
- Size:
- 961 amino acids
- Molecular mass:
- 106561 Da
- Quaternary structure:
-
- Interacts with DBNL/ABP1 and CTTN. May interact with CCPG1 (By similarity). Binds CDC42.
Protein Expression for FGD1 Gene
Post-translational modifications for FGD1 Gene
Other Protein References for FGD1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for FGD1
- Invitrogen Antibodies for FGD1
- antibodies-online Antibodies for FGD1: See all 9
- GeneTex FGD1 antibody for FGD1
-
Santa Cruz Biotechnology (SCBT) Antibodies for FGD1
Protein Products
-
OriGene Purified Proteins for FGD1
- Search Origene for MassSpec and Protein Over-expression Lysates for FGD1
- Origene Custom Protein Services for FGD1
- Search GeneTex for Proteins for FGD1
Assay Products
No data available for DME Specific Peptides for FGD1 Gene
Domains & Families for FGD1 Gene
Gene Families for FGD1 Gene
Protein Domains for FGD1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for FGD1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P98174UniProtKB/Swiss-Prot:
FGD1_HUMAN :- The DH domain is involved in interaction with CCPG1.
- Contains 1 FYVE-type zinc finger.
- Domain:
-
- The DH domain is involved in interaction with CCPG1.
- Contains 1 DH (DBL-homology) domain.
- Contains 2 PH domains.
- Similarity:
-
- Contains 1 FYVE-type zinc finger.
Function for FGD1 Gene
Molecular function for FGD1 Gene
- GENATLAS Biochemistry:
- Rho/Rac,CDC42Hs specific (guanine nucleotide exchange factor) 1,involved in signal transduction and mammalian morphogenesis
- UniProtKB/Swiss-Prot Function:
- Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005085 | guanyl-nucleotide exchange factor activity | TAS | -- |
| GO:0005089 | Rho guanyl-nucleotide exchange factor activity | TAS | -- |
| GO:0031267 | small GTPase binding | IDA | 8969170 |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for FGD1 Gene
- GenomeRNAi human phenotypes for FGD1:
-
- Increased viability
- Increased vaccinia virus (VACV) infection
- Increased gamma-H2AX phosphorylation
- Synthetic lethal with Ras
- Mildly decreased CFP-tsO45G cell surface transport
- Decreased shRNA abundance (Z-score < -2)
- Decreased NF-kappaB reporter expression
- Decreased IL-8 secretion
- Decreased shRNA abundance
- Synthetic lethal with vaccinia virus (VACV) infection
- Increased shRNA abundance (Z-score > 2)
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for FGD1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for FGD1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FGD1 gene
- Search ViGene Biosciences for FGD1
CRISPR Products
-
OriGene CRISPR knockouts for FGD1
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miRNA for FGD1 Gene
- miRTarBase miRNAs that target FGD1
-
- hsa-mir-4640-3p (MIRT610377)
- hsa-mir-2355-3p (MIRT610378)
- hsa-mir-676-3p (MIRT610379)
- hsa-mir-6749-3p (MIRT610380)
- hsa-mir-6852-3p (MIRT610381)
- hsa-mir-3909 (MIRT610382)
- hsa-mir-7151-5p (MIRT610383)
- hsa-mir-4446-5p (MIRT613876)
- hsa-mir-5006-3p (MIRT613877)
- hsa-mir-4755-5p (MIRT613878)
- hsa-mir-670-5p (MIRT613879)
miRNA Products
- Search ViGene Biosciences for FGD1
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for FGD1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FGD1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for FGD1
-
ViGene Biosciences adenoviral particle packaged cDNA for FGD1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FGD1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FGD1 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for FGD1 Gene
Localization for FGD1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for FGD1 Gene
- Cytoplasm. Cell projection, lamellipodium. Cell projection, ruffle. Cytoplasm, cytoskeleton. Note=Associated with membrane ruffles and lamellipodia. {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| golgi apparatus | 5 |
| cytoskeleton | 4 |
| plasma membrane | 3 |
| nucleus | 3 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001726 | ruffle | ISS | -- |
| GO:0005737 | cytoplasm | ISS | -- |
| GO:0005794 | Golgi apparatus | ISS | -- |
| GO:0005829 | cytosol | TAS | -- |
| GO:0005856 | cytoskeleton | IEA | -- |
Pathways & Interactions for FGD1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | p75 NTR receptor-mediated signalling |
.36
|
|
| 2 | Signaling by GPCR | ||
| 3 | Regulation of actin cytoskeleton | ||
| 4 | Actin Nucleation by ARP-WASP Complex |
.41
|
|
| 5 | Signaling by Rho GTPases | ||
Pathways by source for FGD1 Gene
2 BioSystems pathways for FGD1 Gene
10 Reactome pathways for FGD1 Gene
1 KEGG pathway for FGD1 Gene
1 GeneGo (Thomson Reuters) pathway for FGD1 Gene
1 Qiagen pathway for FGD1 Gene
Interacting Proteins for FGD1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007010 | cytoskeleton organization | ISS | -- |
| GO:0007165 | signal transduction | TAS | 8969170 |
| GO:0007275 | multicellular organism development | TAS | 8969170 |
| GO:0008360 | regulation of cell shape | ISS | -- |
| GO:0009887 | animal organ morphogenesis | TAS | 7954831 |
No data available for SIGNOR curated interactions for FGD1 Gene
Drugs & Compounds for FGD1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Guanosine triphosphate | Experimental | Pharma | 0 |
Transcripts for FGD1 Gene
mRNA/cDNA for FGD1 Gene
- (1) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (75) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FGD1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for FGD1
- GenScript: Design CRISPR guide RNA sequences for FGD1
miRNA Products
- Search ViGene Biosciences for FGD1
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for FGD1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FGD1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for FGD1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
This gene is overexpressed in Fetal Brain (56.9) and Urine (6.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for FGD1 Gene
NURSA nuclear receptor signaling pathways regulating expression of FGD1 Gene:
FGD1SOURCE GeneReport for Unigene cluster for FGD1 Gene:
Hs.709201mRNA Expression by UniProt/SwissProt for FGD1 Gene:
P98174-FGD1_HUMAN
Tissue specificity:
Expressed in fetal heart, brain, lung, kidney and placenta. Less expressed in liver; adult heart, brain, lung, pancreas and skeletal muscle.
Primer Products
-
OriGene qPCR primer pairs and template standards for FGD1
-
OriGene qPCR primer pairs for FGD1
No data available for mRNA differential expression in normal tissues for FGD1 Gene
Orthologs for FGD1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FGD1 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | FGD1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | FGD1 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Fgd1 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Fgd1 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | FGD1 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | FGD1 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | FGD1 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | fgd1 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | fgd1 34 35 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | RhoGEF4 35 |
|
ManyToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | exc-5 36 35 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.6211 35 |
|
OneToMany |
- Species where no ortholog for FGD1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for FGD1 Gene
Variants for FGD1 Gene
| SNP ID | Clin | Chr 0X pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs137853264 | Aarskog-Scott syndrome (AAS) [MIM:305400], Pathogenic | 54,465,522(-) | CCCCC(A/G)CTATG | reference, missense | |
| rs28935497 | Aarskog-Scott syndrome (AAS) [MIM:305400], Pathogenic | 54,456,233(-) | AGACC(A/G)ATACC | reference, missense | |
| VAR_019268 | Aarskog-Scott syndrome (AAS) [MIM:305400] | ||||
| VAR_019270 | Aarskog-Scott syndrome (AAS) [MIM:305400] | ||||
| VAR_019271 | Aarskog-Scott syndrome (AAS) [MIM:305400] |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv435891 | CNV | deletion | 17901297 |
| esv2740175 | CNV | deletion | 23290073 |
Residual Variation Intolerance Score:
7.99% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.41;
42.58% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FGD1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FGD1 Gene
Disorders for FGD1 Gene
(8) MalaCards diseases for FGD1 Gene - From: OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| aarskog-scott syndrome |
|
|
| fgd1-related x-linked mental retardation |
|
|
| scott syndrome |
|
|
| crane-heise syndrome |
|
|
| unilateral focal polymicrogyria |
|
|
Search FGD1 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
FGD1_HUMAN- Aarskog-Scott syndrome (AAS) [MIM:305400]: A rare multisystemic disorder characterized by disproportionately short stature, and by facial, skeletal and urogenital anomalies. Some patients manifest mental retardation, attention deficit disorder and hyperactivity. {ECO:0000269 PubMed:10930571, ECO:0000269 PubMed:11093277, ECO:0000269 PubMed:14560308}. Note=The disease is caused by mutations affecting the gene represented in this entry.
- Note=Defects in FGD1 are found in a patient with non-syndromal X-linked mental retardation. {ECO:0000269 PubMed:11940089}.
Genatlas disease for FGD1 Gene
Aarskog syndrome,faciogenital dysplasia and brachydactyly
Relevant External Links for FGD1
Publications for FGD1 Gene
- Phenotypic and molecular characterisation of the Aarskog-Scott syndrome: a survey of the clinical variability in light of FGD1 mutation analysis in 46 patients. (PMID: 14560308) Orrico A. … Sorrentino V. (Eur. J. Hum. Genet. 2004) 3 4 22 46 64
- Non-syndromic X-linked mental retardation associated with a missense mutation (P312L) in the FGD1 gene. (PMID: 11940089) Lebel R.R. … Schwartz C.E. (Clin. Genet. 2002) 3 4 22 46 64
- A mutation in the pleckstrin homology (PH) domain of the FGD1 gene in an Italian family with faciogenital dysplasia (Aarskog-Scott syndrome). (PMID: 10930571) Orrico A. … Sorrentino V. (FEBS Lett. 2000) 3 4 22 64
- Two novel mutations confirm FGD1 is responsible for the Aarskog syndrome. (PMID: 11093277) Schwartz C.E. … Neri G. (Eur. J. Hum. Genet. 2000) 3 4 22 64
- Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: a putative Rho/Rac guanine nucleotide exchange factor. (PMID: 7954831) Pasteris N.G. … Gorski J.L. (Cell 1994) 3 4 22 64
Products for FGD1 Gene
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- Novus Biologicals Antibodies for FGD1
- Novus Biologicals proteins and lysates for FGD1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ViGene Biosciences adenoviral particle packaged cDNA for FGD1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for FGD1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for FGD1 gene
- Search ViGene Biosciences for FGD1
- Santa Cruz Biotechnology (SCBT) Antibodies for FGD1
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- Browse Santa Cruz Biotechnology (SCBT) for FGD1 CRISPR
- Horizon Cell Lines for FGD1
- Cyagen custom Knockout/knockin (KOKI) mouse models for FGD1
- VectorBuilder custom plasmid, inducible vectors for FGD1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FGD1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FGD1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
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