Aliases for FFAR4 Gene
Aliases for FFAR4 Gene
External Ids for FFAR4 Gene
- HGNC: 19061
- Entrez Gene: 338557
- Ensembl: ENSG00000186188
- OMIM: 609044
- UniProtKB: Q5NUL3
Previous HGNC Symbols for FFAR4 Gene
- GPR129
- GPR120
- O3FAR1
Previous GeneCards Identifiers for FFAR4 Gene
- GC10P095329
Summaries for FFAR4 Gene
-
This gene encodes a G protein-coupled receptor (GPR) which belongs to the rhodopsin family of GPRs. The encoded protein functions as a receptor for free fatty acids, including omega-3, and participates in suppressing anti-inflammatory responses and insulin sensitizing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
GeneCards Summary for FFAR4 Gene
FFAR4 (Free Fatty Acid Receptor 4) is a Protein Coding gene. Diseases associated with FFAR4 include Obesity. Among its related pathways are Incretin synthesis, secretion, and inactivation and Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity and taste receptor activity.
UniProtKB/Swiss-Prot for FFAR4 Gene
-
Receptor for medium and long-chain free fatty acids (FFAs). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects, particularly in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1-dependent effect, but independent of the G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediate the taste of fatty acids. Mediates FFA-induced inhibition of apoptosis in enteroendocrine cells. May play a role in the regulation of adipocyte development and differentiation.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FFAR4 Gene
Genomics for FFAR4 Gene
Regulatory Elements for FFAR4 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH10G093514 | 1.1 | Ensembl ENCODE dbSUPER | 10.9 | -50.5 | -50503 | 2.2 | KLF1 BHLHE40 REST ZIC2 ATF2 NR2F2 ZNF664 TCF12 PRDM6 ZNF652 | CEP55 FFAR4 CYP26A1 RNA5SP323 GC10M093511 GC10M093549 |
| GH10G093591 | 0.7 | ENCODE | 12.2 | +25.6 | 25575 | 1.2 | PAF1 SOX13 NR2F1 HLF MAX NR2F2 YY1 SSRP1 JUND IKZF1 | PDE6C FFAR4 RBP4 GC10P093599 GC10P093568 |
| GH10G093572 | 0.5 | Ensembl | 10.8 | +7.2 | 7197 | 1.2 | GATA2 ETV1 EP300 | FFAR4 RBP4 GC10P093568 GC10P093599 |
| GH10G093550 | 0.4 | ENCODE | 7 | -15.4 | -15386 | 0.2 | SAP130 NCOR1 | FFAR4 GC10M093549 RNA5SP323 GC10M093511 |
| GH10G093321 | 0.4 | FANTOM5 | 4.2 | -244.8 | -244786 | 0.0 | ZNF507 | FFAR4 RPL17P34 GC10P093383 |
Regulatory Element Products
Genomic Location for FFAR4 Gene
- Chromosome:
- 10
- Start:
- 93,566,204 bp from pter
- End:
- 93,604,480 bp from pter
- Size:
- 38,277 bases
- Orientation:
- Plus strand
Genomic View for FFAR4 Gene
- Cytogenetic band:
-
- 10q23.33 by Ensembl
- 10q23.33 by Entrez Gene
- 10q23.33 by HGNC
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FFAR4 Gene
Proteins for FFAR4 Gene
-
Protein details for FFAR4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q5NUL3-FFAR4_HUMAN
- Recommended name:
- Free fatty acid receptor 4
- Protein Accession:
- Q5NUL3
- Q495H1
- Q5VY25
- Q5VY26
- Q7Z605
- Q86SM7
Protein attributes for FFAR4 Gene
- Size:
- 377 amino acids
- Molecular mass:
- 42241 Da
- Quaternary structure:
-
- Interacts with ARRB2 following docosahexaenoic acid (DHA) stimulation.
- Miscellaneous:
-
- It has been shown that FFA alpha-linolenic acid stimulates secretion of glucagon-like peptide 1 (GLP-1) from the gastro-intestinal tract (PubMed:15619630). However, this ligand is an agonist of both FFAR4 and FFAR1 and the latter has been shown to mediate GLP-1 release too (PubMed:18519800). So the precise role of FFAR4 in mediating needs to be confirmed.
Post-translational modifications for FFAR4 Gene
- Phosphorylated. FFA stimulation facilitates phosphorylation.
- Glycosylation at Asn21
- Modification sites at PhosphoSitePlus
Other Protein References for FFAR4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for FFAR4
- Novus Biologicals Antibodies for FFAR4
- Invitrogen Antibodies for FFAR4
- antibodies-online Antibodies for FFAR4: See all 82
- GeneTex FFAR4 antibody for FFAR4
-
Santa Cruz Biotechnology (SCBT) Antibodies for FFAR4
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for FFAR4
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- Search GeneTex for Proteins for FFAR4
Assay Products
- antibodies-online Kits for FFAR4: See all 17
No data available for DME Specific Peptides for FFAR4 Gene
Domains & Families for FFAR4 Gene
Gene Families for FFAR4 Gene
Protein Domains for FFAR4 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for FFAR4 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q5NUL3- Family:
-
- Belongs to the G-protein coupled receptor 1 family.
Function for FFAR4 Gene
Molecular function for FFAR4 Gene
- UniProtKB/Swiss-Prot Function:
- Receptor for medium and long-chain free fatty acids (FFAs). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects, particularly in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1-dependent effect, but independent of the G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediate the taste of fatty acids. Mediates FFA-induced inhibition of apoptosis in enteroendocrine cells. May play a role in the regulation of adipocyte development and differentiation.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004930 | G-protein coupled receptor activity | IEA,IBA | -- |
| GO:0005504 | fatty acid binding | IEA,ISS | -- |
| GO:0008289 | lipid binding | IEA | -- |
| GO:0008527 | taste receptor activity | IEA,IBA | -- |
| GO:0042277 | NOT peptide binding | IBA | -- |
Phenotypes for FFAR4 Gene
- MGI mutant phenotypes for FFAR4:
- inferred from 4 alleles
- GenomeRNAi human phenotypes for FFAR4:
Animal Models for FFAR4 Gene
Animal Model Products
-
Taconic Biosciences Mouse Models for FFAR4
-
ViGene Biosciences lentiviral particle packaged cDNA for FFAR4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FFAR4 gene
- Search ViGene Biosciences for FFAR4
CRISPR Products
-
OriGene CRISPR knockouts for FFAR4
- GenScript: Design CRISPR guide RNA sequences for FFAR4
miRNA for FFAR4 Gene
- miRTarBase miRNAs that target FFAR4
-
- hsa-mir-640 (MIRT631505)
- hsa-mir-3692-5p (MIRT631506)
- hsa-mir-6778-3p (MIRT631507)
- hsa-mir-150-5p (MIRT631508)
- hsa-mir-1224-3p (MIRT631509)
- hsa-mir-186-3p (MIRT631510)
- hsa-mir-548av-3p (MIRT631511)
- hsa-mir-548s (MIRT639378)
- hsa-mir-340-5p (MIRT639379)
- hsa-mir-3926 (MIRT639380)
- hsa-mir-6765-3p (MIRT639381)
- hsa-mir-3190-5p (MIRT639382)
- hsa-mir-3065-5p (MIRT639383)
- hsa-mir-501-5p (MIRT639384)
- hsa-mir-500a-5p (MIRT639385)
- hsa-mir-7-2-3p (MIRT639386)
- hsa-mir-7-1-3p (MIRT639387)
- hsa-mir-5089-5p (MIRT645779)
- hsa-mir-5589-5p (MIRT645780)
- hsa-mir-4731-5p (MIRT645781)
- hsa-mir-6506-5p (MIRT645782)
- hsa-mir-619-5p (MIRT645783)
- hsa-mir-500a-3p (MIRT645784)
- hsa-mir-6804-3p (MIRT645785)
- hsa-mir-3130-3p (MIRT645786)
- hsa-mir-1273g-3p (MIRT645787)
- hsa-mir-5590-3p (MIRT645788)
- hsa-mir-142-5p (MIRT645789)
- hsa-mir-378a-5p (MIRT679174)
- hsa-mir-6821-3p (MIRT679175)
- hsa-mir-6790-3p (MIRT679176)
- hsa-mir-3653-5p (MIRT679177)
- hsa-mir-3934-5p (MIRT679178)
- hsa-mir-764 (MIRT679179)
- hsa-mir-125a-3p (MIRT679180)
miRNA Products
- Search ViGene Biosciences for FFAR4
Inhibitory RNA Products
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-
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Clone Products
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Cell Line Products
-
Horizon Cell Lines for FFAR4
-
ViGene Biosciences adenoviral particle packaged cDNA for FFAR4 gene
-
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-
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Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for FFAR4 Gene
Localization for FFAR4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for FFAR4 Gene
- Cell membrane; Multi-pass membrane protein. Note=Colocalized with ARRB2 following DHA treatment. {ECO:0000250}.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | ISS | -- |
| GO:0005887 | integral component of plasma membrane | IBA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
| GO:0030139 | endocytic vesicle | IEA | -- |
Pathways & Interactions for FFAR4 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Peptide ligand-binding receptors | ||
| 2 | Incretin synthesis, secretion, and inactivation | ||
| 3 | Signaling by GPCR | ||
| 4 | Free fatty acid receptors | ||
| 5 | Metabolism of proteins | ||
Pathways by source for FFAR4 Gene
9 Reactome pathways for FFAR4 Gene
Interacting Proteins for FFAR4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007165 | signal transduction | IEA | -- |
| GO:0007186 | G-protein coupled receptor signaling pathway | IEA | -- |
| GO:0010827 | regulation of glucose transport | ISS,IEA | -- |
| GO:0032870 | NOT cellular response to hormone stimulus | IBA | -- |
| GO:0043066 | negative regulation of apoptotic process | ISS,IEA | -- |
No data available for SIGNOR curated interactions for FFAR4 Gene
Drugs & Compounds for FFAR4 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| oleic acid | Approved, Vet_approved | Pharma | Full agonist, Agonist | 0 | ||
| MYRISTIC ACID | Experimental | Pharma | 0 | |||
| PRO-542 | Investigational | Pharma | Target | 0 | ||
| TNX-355 | Investigational | Pharma | Target | 0 | ||
| GSK 137647 | Pharma | FFA4/GPR120 antagonist,potent and selective, Potent and selective FFA4 (GPR120) agonist | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| TC-G 1008 |
|
1621175-65-2 |
|
|
(5) Tocris Compounds for FFAR4 Gene
| Compound | Action | Cas Number |
|---|---|---|
| GSK 137647 | Potent and selective FFA4 (GPR120) agonist | 349085-82-1 |
| NIBR 189 | Potent and selective EBI2 (GPR183) receptor antagonist | 1599432-08-2 |
| TC-G 1008 | Potent and selective GPR39 agonist | 1621175-65-2 |
| TC-O 9311 | Potent and selective GPR139 agonist | 444932-31-4 |
| TUG 891 | Potent and selective FFA4 (GPR120) agonist | 1374516-07-0 |
(7) ApexBio Compounds for FFAR4 Gene
| Compound | Action | Cas Number |
|---|---|---|
| 4-CMTB | 300851-67-6 | |
| AH 7614 | FFA4/GPR120 antagonist | 6326-06-3 |
| GPR120 modulator 1 | GPR120 modulator | 1050506-75-6 |
| GPR120 modulator 2 | GPR120 modulator | 1050506-87-0 |
| GSK 137647 | FFA4/GPR120 antagonist,potent and selective | 349085-82-1 |
| MEDICA 16 | 87272-20-6 | |
| TUG 424 | 1082058-99-8 |
Drug Products
- ApexBio compounds for FFAR4
Transcripts for FFAR4 Gene
mRNA/cDNA for FFAR4 Gene
- (3) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (9) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FFAR4 Gene
CRISPR Products
-
OriGene CRISPR knockouts for FFAR4
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miRNA Products
- Search ViGene Biosciences for FFAR4
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FFAR4
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-
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Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for FFAR4
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Flow Cytometry Products
Expression for FFAR4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Epithelial Cells (Uncategorized)
- Liver (Hepatobiliary System)
mRNA differential expression in normal tissues according to GTEx for FFAR4 Gene
NURSA nuclear receptor signaling pathways regulating expression of FFAR4 Gene:
FFAR4SOURCE GeneReport for Unigene cluster for FFAR4 Gene:
Hs.661022mRNA Expression by UniProt/SwissProt for FFAR4 Gene:
Q5NUL3-FFAR4_HUMANEvidence on tissue expression from TISSUES for FFAR4 Gene
- Intestine(2.4)
- Pancreas(2.4)
- Stomach(2)
Primer Products
-
OriGene qPCR primer pairs for FFAR4
-
OriGene qPCR primer pairs and template standards for FFAR4
No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for FFAR4 Gene
Orthologs for FFAR4 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FFAR4 35 |
|
OneToOne | |
| O3FAR1 34 |
|
||||
| dog (Canis familiaris) |
Mammalia | O3FAR1 34 |
|
||
| FFAR4 35 |
|
OneToOne | |||
| cow (Bos Taurus) |
Mammalia | LOC533266 34 |
|
||
| FFAR4 35 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Ffar4 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Ffar4 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | FFAR4 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | O3FAR1 34 |
|
||
| FFAR4 35 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | FFAR4 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | ffar4 34 |
|
- Species where no ortholog for FFAR4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for FFAR4 Gene
(1) SIMAP similar genes for FFAR4 Gene using alignment to 2 proteins:
No data available for Paralogs for FFAR4 Gene
Variants for FFAR4 Gene
Polymorphic Variants from UniProtKB/Swiss-Prot for FFAR4 Gene
- FFAR4_HUMAN-Q5NUL3
- Genetic variations in FFAR4 define the body mass index quantitative trait locus 10 (BMIQ10) [MIM:607514]. Variance in body mass index is a susceptibility factor for obesity.
| SNP ID | Clin | Chr 10 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs116454156 | other | 93,587,284(+) | GATCC(A/G)CGTGT | reference, missense | |
| rs1000116072 | -- | 93,572,085(+) | TAATG(C/T)GTATT | intron-variant | |
| rs1000133083 | -- | 93,586,891(+) | GAACC(C/T)TAAGC | intron-variant | |
| rs1000171727 | -- | 93,570,425(+) | GTCTC(A/G)CATTT | intron-variant | |
| rs1000330755 | -- | 93,568,813(+) | TGGGG(-/TGTT)TGTTT | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3579075 | CNV | loss | 25503493 |
Relevant External Links for FFAR4 Gene
Disorders for FFAR4 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| obesity |
|
|
Relevant External Links for FFAR4
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- FFAR4
No data available for UniProtKB/Swiss-Prot and Genatlas for FFAR4 Gene
Publications for FFAR4 Gene
- Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120. (PMID: 15619630) Hirasawa A. … Tsujimoto G. (Nat. Med. 2005) 2 3 4 22 64
- Agonism with the omega-3 fatty acids alpha-linolenic acid and docosahexaenoic acid mediates phosphorylation of both the short and long isoforms of the human GPR120 receptor. (PMID: 20471368) Burns R.N. … Moniri N.H. (Biochem. Biophys. Res. Commun. 2010) 2 3 4 64
- Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human. (PMID: 22343897) Ichimura A. … Froguel P. (Nature 2012) 3 4 64
- GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects. (PMID: 20813258) Oh D.Y. … Olefsky J.M. (Cell 2010) 2 3 64
- Free fatty acid receptors act as nutrient sensors to regulate energy homeostasis. (PMID: 19460454) Ichimura A. … Tsujimoto G. (Prostaglandins Other Lipid Mediat. 2009) 3 22 64
Products for FFAR4 Gene
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- R&D Systems cDNA Clones for FFAR4 (FFAR4/GPR120)
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- Novus Biologicals
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- antibodies-online Antibodies for FFAR4: See all 82
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- Search antibodies-online for proteins
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- GeneTex FFAR4 antibody for FFAR4
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- ViGene Biosciences adenoviral particle packaged cDNA for FFAR4 gene
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- Search ViGene Biosciences for FFAR4
- Santa Cruz Biotechnology (SCBT) Antibodies for FFAR4
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- Horizon Cell Lines for FFAR4
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- VectorBuilder custom plasmid, inducible vectors for FFAR4
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- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
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- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FFAR4 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
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- (150) St John's Lab
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- (152) ProteoGenix
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