Aliases for FFAR1 Gene
Subcategory (RNA class) for FFAR1 Gene
lncRNA
Aliases for FFAR1 Gene
External Ids for FFAR1 Gene
- HGNC: 4498
- Entrez Gene: 2864
- Ensembl: ENSG00000126266
- OMIM: 603820
- UniProtKB: O14842
ORGUL Members for FFAR1 Gene
Previous HGNC Symbols for FFAR1 Gene
- GPR40
Previous GeneCards Identifiers for FFAR1 Gene
- GC19P040535
- GC19P035842
- GC19P032350
- GC19P035503
- GC19P035513
- GC19P035522
- GC19P035541
- GC19P036131
Summaries for FFAR1 Gene
-
This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for medium and long chain free fatty acids and may be involved in the metabolic regulation of insulin secretion. Polymorphisms in this gene may be associated with type 2 diabetes. [provided by RefSeq, Apr 2009]
GeneCards Summary for FFAR1 Gene
FFAR1 (Free Fatty Acid Receptor 1) is a Protein Coding gene, and is affiliated with the lncRNA class. Diseases associated with FFAR1 include Refsum Disease. Among its related pathways are Incretin synthesis, secretion, and inactivation and RET signaling. GO annotations related to this gene include G-protein coupled receptor activity and guanyl-nucleotide exchange factor activity. An important paralog of this gene is FFAR3.
UniProtKB/Swiss-Prot for FFAR1 Gene
-
G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis; receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway.
-
Free Fatty Acid (FFA) receptors are a group of Gq/11 protein-coupled receptors that are currently divided into FFA1, FFA2 and FFA3 subtypes. FFA receptors are concentrated in the pancreatic islet cells (particularly FFA1) and in the brain.
No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FFAR1 Gene
Genomics for FFAR1 Gene
Regulatory Elements for FFAR1 Gene
Enhancers for FFAR1 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FFAR1 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the FFAR1 gene promoter:
Regulatory Element Products
Genomic Location for FFAR1 Gene
- Chromosome:
- 19
- Start:
- 35,351,542 bp from pter
- End:
- 35,353,862 bp from pter
- Size:
- 2,321 bases
- Orientation:
- Plus strand
Genomic View for FFAR1 Gene
Genes around FFAR1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.12 by Ensembl
- 19q13.12 by Entrez Gene
- 19q13.12 by HGNC
FFAR1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FFAR1 Gene
Proteins for FFAR1 Gene
-
Protein details for FFAR1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O14842-FFAR1_HUMAN
- Recommended name:
- Free fatty acid receptor 1
- Protein Accession:
- O14842
- Q0VAS2
- Q4VBL4
Protein attributes for FFAR1 Gene
- Size:
- 300 amino acids
- Molecular mass:
- 31457 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for FFAR1 Gene
Other Protein References for FFAR1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for FFAR1
-
Custom Antibody ServicesOriGene Antibodies for FFAR1
- Novus Biologicals Antibodies for FFAR1
- Invitrogen Antibodies for FFAR1
- antibodies-online Antibodies for FFAR1: See all 89
- GeneTex FFAR1 antibody for FFAR1
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for FFAR1
- Origene Custom Protein Services for FFAR1
- Novus Biologicals lysates for FFAR1
- Search GeneTex for Proteins for FFAR1
No data available for DME Specific Peptides for FFAR1 Gene
Domains & Families for FFAR1 Gene
Gene Families for FFAR1 Gene
- HGNC:
- IUPHAR :
Protein Domains for FFAR1 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for FFAR1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O14842- Family:
-
- Belongs to the G-protein coupled receptor 1 family.
Function for FFAR1 Gene
Molecular function for FFAR1 Gene
- UniProtKB/Swiss-Prot EnzymeRegulation:
- The receptor is strongly activated by gamma-linolenic acid, while myristate gives a lower response. It is also activated by phytanic acid and pristanic acid (PubMed:21570468). Is also activated by synthetic agonists, such as TAK-875 (fasiglifam); this compound is a partial agonist and potentiates the activity of the endogenous ligand gamma-linolenic acid (PubMed:24130766).
- UniProtKB/Swiss-Prot Function:
- G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis; receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004930 | G-protein coupled receptor activity | TAS | 9344866 |
| GO:0005085 | guanyl-nucleotide exchange factor activity | TAS | -- |
| GO:0008289 | lipid binding | IEA | -- |
| GO:0045125 | bioactive lipid receptor activity | IDA | 24130766 |
Phenotypes for FFAR1 Gene
- MGI mutant phenotypes for FFAR1:
- inferred from 4 alleles
- GenomeRNAi human phenotypes for FFAR1:
-
- Increased vaccinia virus (VACV) infection
- Decreased viability
- Decreased hepcidin::fluc mRNA expression
- shRNA abundance <= 50%
- Negative genetic interaction between PTEN-/- and PTEN+/+
- Decreased shRNA abundance
- Increased cell number in S
- Increased circadian period length
- Upregulation of Wnt pathway
- Increased Nanog expression
Animal Models for FFAR1 Gene
Animal Model Products
-
Taconic Biosciences Mouse Models for FFAR1
-
ViGene Biosciences lentiviral particle packaged cDNA for FFAR1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FFAR1 gene
- Search ViGene Biosciences for FFAR1
CRISPR Products
-
OriGene CRISPR knockouts for FFAR1
-
Santa Cruz Biotechnology (SCBT) CRISPR for FFAR1
- GenScript: Design CRISPR guide RNA sequences for FFAR1
miRNA for FFAR1 Gene
- miRTarBase miRNAs that target FFAR1
miRNA Products
- Search ViGene Biosciences for FFAR1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FFAR1
- Browse OriGene Inhibitory RNA Products For FFAR1
-
ViGene Biosciences ready-to-package AAV shRNAs for FFAR1 gene
Clone Products
-
OriGene ORF clones in human for FFAR1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for FFAR1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for FFAR1
- R&D Systems cDNA Clones for FFAR1 (FFAR1/GPR40)
Cell Line Products
-
Horizon Cell Lines for FFAR1
-
ViGene Biosciences adenoviral particle packaged cDNA for FFAR1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FFAR1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FFAR1 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for FFAR1 Gene
Localization for FFAR1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for FFAR1 Gene
- Cell membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 1 |
| mitochondrion | 1 |
| peroxisome | 1 |
| nucleus | 1 |
| cytosol | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0005887 | integral component of plasma membrane | TAS,IDA | 25043059 |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for FFAR1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Peptide ligand-binding receptors | ||
| 2 | Signaling by GPCR | ||
| 3 | Incretin synthesis, secretion, and inactivation | ||
| 4 | Free fatty acids regulate insulin secretion | ||
| 5 | RET signaling | ||
Pathways by source for FFAR1 Gene
1 BioSystems pathway for FFAR1 Gene
1 KEGG pathway for FFAR1 Gene
Interacting Proteins for FFAR1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007165 | signal transduction | IEA | -- |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS,IEA | -- |
| GO:0030073 | insulin secretion | IEA | -- |
| GO:0032024 | positive regulation of insulin secretion | IEA | -- |
| GO:0042593 | glucose homeostasis | IEA | -- |
No data available for SIGNOR curated interactions for FFAR1 Gene
Drugs & Compounds for FFAR1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Icosapent | Approved | Nutra | Target, agonist | Endogenous polyunsaturated fatty acid; stimulates ERK1/2 phosphorylation | 0 | |
| oleic acid | Approved, Vet_approved | Pharma | Full agonist, Agonist | 0 | ||
| Rosiglitazone | Approved, Investigational | Pharma | Full agonist, Agonist, agonist | Potent PPARγ agonist, Potent and selective PPARgamma agonist; antidiabetic agent. | 220 | |
| alpha-linolenic acid | Approved | Nutra | Full agonist, Agonist | 0 | ||
| Palmitic Acid | Experimental | Pharma | Full agonist, Agonist | 22 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| TUG424 |
|
Full agonist, Agonist |
|
|||
| DC 260126 |
|
346692-04-4 |
|
|
(5) Tocris Compounds for FFAR1 Gene
| Compound | Action | Cas Number |
|---|---|---|
| 4-CMTB | FFA2 agonist; also exhibits positive allosteric modulatory activity | 300851-67-6 |
| AH 7614 | Selective FFA4 (GPR120) antagonist | 6326-06-3 |
| DC 260126 | FFA1 (GPR40) antagonist | 346692-04-4 |
| GW 9508 | Potent and selective FFA1 (GPR40) agonist | 885101-89-3 |
| MEDICA 16 | FFA1 (GPR40) agonist; also inhibits ATP citrate lyase | 87272-20-6 |
(11) ApexBio Compounds for FFAR1 Gene
| Compound | Action | Cas Number |
|---|---|---|
| 4-CMTB | 300851-67-6 | |
| AMG837 | GPR40 agonist,orally bioavailable | 865231-46-5 |
| AS 2034178 | Selective FFA1/GPR40 agonist | 1030846-42-4 |
| GPR40 Activator 1 | 1309435-60-6 | |
| GSK1292263 | Novel GPR119 agonist | 1032823-75-8 |
| GW-1100 | GPR40 antagonist | 306974-70-9 |
| GW9508 | FFA1/GPR40 agonist,potent and selective | 885101-89-3 |
| MEDICA 16 | 87272-20-6 | |
| TAK-875 | GPR40 agonist | 1000413-72-8 |
| TUG 424 | 1082058-99-8 | |
| TUG-770 | FFA1/GPR40 agonist | 1402601-82-4 |
Transcripts for FFAR1 Gene
mRNA/cDNA for FFAR1 Gene
- (1) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (16) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FFAR1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for FFAR1
-
Santa Cruz Biotechnology (SCBT) CRISPR for FFAR1
- GenScript: Design CRISPR guide RNA sequences for FFAR1
miRNA Products
- Search ViGene Biosciences for FFAR1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FFAR1
- Browse OriGene Inhibitory RNA Products For FFAR1
-
ViGene Biosciences ready-to-package AAV shRNAs for FFAR1 gene
Clone Products
-
OriGene ORF clones in human for FFAR1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for FFAR1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for FFAR1
- R&D Systems cDNA Clones for FFAR1 (FFAR1/GPR40)
Flow Cytometry Products
Expression for FFAR1 Gene
mRNA differential expression in normal tissues according to GTEx for FFAR1 Gene
This gene is overexpressed in Pancreas (x7.4), Ovary (x7.0), and Brain - Spinal cord (cervical c-1) (x6.2).
NURSA nuclear receptor signaling pathways regulating expression of FFAR1 Gene:
FFAR1SOURCE GeneReport for Unigene cluster for FFAR1 Gene:
Hs.248127mRNA Expression by UniProt/SwissProt for FFAR1 Gene:
O14842-FFAR1_HUMAN
Tissue specificity:
Detected in brain and pancreas. Detected in pancreatic beta cells.
Evidence on tissue expression from TISSUES for FFAR1 Gene
- Pancreas(2.6)
Primer Products
-
OriGene qPCR primer pairs for FFAR1
-
OriGene qPCR primer pairs and template standards for FFAR1
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for FFAR1 Gene
Orthologs for FFAR1 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FFAR1 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | FFAR1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | FFAR1 35 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Ffar1 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Ffar1 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | FFAR1 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | FFAR1 35 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | FFAR1 35 |
|
OneToOne |
- Species where no ortholog for FFAR1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for FFAR1 Gene
Variants for FFAR1 Gene
| SNP ID | Clin | Chr 19 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000167582 | -- | 35,351,730(+) | TCTGC(C/T)CCTGA | reference, missense | |
| rs1003048896 | -- | 35,351,122(+) | GCTCA(A/G)GAGTC | upstream-variant-2KB | |
| rs1003438044 | -- | 35,352,122(+) | TGCTC(C/T)TTTTT | reference, missense | |
| rs1003512240 | -- | 35,350,977(+) | TCCCT(G/T)GGGGA | upstream-variant-2KB | |
| rs1004896169 | -- | 35,349,638(+) | GCTGT(-/C)CCCCC | upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2718493 | CNV | deletion | 23290073 |
| esv2758758 | CNV | loss | 17122850 |
| nsv1067129 | CNV | loss | 25217958 |
| nsv1160606 | CNV | deletion | 26073780 |
| nsv173 | CNV | deletion | 15895083 |
| nsv2471 | CNV | deletion | 18451855 |
| nsv510765 | CNV | deletion | 20534489 |
| nsv833810 | CNV | gain | 17160897 |
Gene Damage Index Score:
1.59;
30.70% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FFAR1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FFAR1 Gene
Disorders for FFAR1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| refsum disease |
|
|
Search FFAR1 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for FFAR1
No data available for UniProtKB/Swiss-Prot and Genatlas for FFAR1 Gene
Publications for FFAR1 Gene
- Two arginine-glutamate ionic locks near the extracellular surface of FFAR1 gate receptor activation. (PMID: 19068482) Sum C.S. … Gershengorn M.C. (J. Biol. Chem. 2009) 3 4 22 64
- Loss-of-function mutation of the GPR40 gene associates with abnormal stimulated insulin secretion by acting on intracellular calcium mobilization. (PMID: 18583466) Vettor R. … Frittitta L. (J. Clin. Endocrinol. Metab. 2008) 3 22 46 64
- GPR40 gene Arg211His polymorphism may contribute to the variation of insulin secretory capacity in Japanese men. (PMID: 15736105) Ogawa T. … Saruta T. (Metab. Clin. Exp. 2005) 3 22 46 64
- Studies of relationships between variation of the human G protein-coupled receptor 40 Gene and Type 2 diabetes and insulin release. (PMID: 15606695) Hamid Y.H. … Hansen T. (Diabet. Med. 2005) 3 22 46 64
- High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875. (PMID: 25043059) Srivastava A. … Okada K. (Nature 2014) 3 4 64
Products for FFAR1 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- R&D Systems cDNA Clones for FFAR1 (FFAR1/GPR40)
- Browse Primary Antibodies
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- Browse Cell Selection and Detection Kits
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- Custom Antibody ServicesOriGene Antibodies for FFAR1
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for FFAR1
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- GenScript: Design CRISPR guide RNA sequences for FFAR1
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- CloneReady with Over 120,000 Genes
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- Novus Biologicals Antibodies for FFAR1
- Novus Biologicals lysates for FFAR1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Taconic Biosciences Mouse Models for FFAR1
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for FFAR1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ApexBio compounds for FFAR1
- Addgene plasmids for FFAR1
- antibodies-online Antibodies for FFAR1: See all 89
- antibodies-online Kits for FFAR1: See all 19
- Search antibodies-online for proteins
- Search antibodies-online for peptides
- GeneTex FFAR1 antibody for FFAR1
- Search GeneTex for Proteins for FFAR1
- ViGene Biosciences adenoviral particle packaged cDNA for FFAR1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for FFAR1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for FFAR1 gene
- Search ViGene Biosciences for FFAR1
- Search Santa Cruz Biotechnology (SCBT) for FFAR1 Antibodies
- Search Santa Cruz Biotechnology (SCBT) for FFAR1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for FFAR1
- Horizon Cell Lines for FFAR1
- Cyagen custom Knockout/knockin (KOKI) mouse models for FFAR1
- VectorBuilder custom plasmid, inducible vectors for FFAR1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FFAR1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FFAR1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer