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FEZF2 Gene

protein-coding   GIFtS: 43
GCID: GC03M062355

FEZ Family Zinc Finger 2

(Previous name: zinc finger protein 312)
(Previous symbol: ZNF312)
  See FEZF2-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
FEZ Family Zinc Finger 21 2     TOF2 5
ZNF3121 2 3 5     FEZ2
Zinc Finger Protein 3121 2 3     ZFP3122
FEZL2 3 5     Fez Family Zinc Finger Protein 22
Forebrain Embryonic Zinc Finger-Like Protein 22 3     Zinc Finger Protein Fez-Like3

External Ids:    HGNC: 135061   Entrez Gene: 550792   Ensembl: ENSG000001532667   OMIM: 6074145   UniProtKB: Q8TBJ53   

Export aliases for FEZF2 gene to outside databases

Previous GC identifer: GC03M062331


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for FEZF2 Gene:
FEZF2 (FEZ family zinc finger 2) is a protein-coding gene. Diseases associated with FEZF2 include uterine inversion, and breast metaplastic carcinoma. GO annotations related to this gene include RNA polymerase II core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is GFI1.

UniProtKB/Swiss-Prot: FEZF2_HUMAN, Q8TBJ5
Function: Transcription repressor. Required for the specification of corticospinal motor neurons and other
subcerebral projection neurons. May play a role in layer and neuronal subtype-specific patterning of subcortical
projections and axonal fasciculation. Controls the development of dendritic arborization and spines of large
layer V pyramidal neurons. May be involved in innate immunity (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000003.11  NC_018914.2  NT_022517.19  
Regulatory elements:
   Regulatory transcription factor binding sites in the FEZF2 gene promoter:
         E2F-3a   E2F-4   E2F-5   AML1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFEZF2 promoter sequence
   Search Chromatin IP Primers for FEZF2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FEZF2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p14.2   Ensembl cytogenetic band:  3p14.2   HGNC cytogenetic band: 3p21.1

FEZF2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FEZF2 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M062355:  view genomic region     (about GC identifiers)

Start:
62,355,347 bp from pter      End:
62,359,999 bp from pter
Size:
4,653 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: FEZF2_HUMAN, Q8TBJ5 (See protein sequence)
Recommended Name: Fez family zinc finger protein 2  
Size: 459 amino acids; 48811 Da
Secondary accessions: A8K349 Q9BZ91 Q9NWB9
Alternative splicing: 2 isoforms:  Q8TBJ5-1   Q8TBJ5-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FEZF2: NX_Q8TBJ5

Explore proteomics data for FEZF2 at MOPED


See FEZF2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_060478.3  
ENSEMBL proteins: 
 ENSP00000418589   ENSP00000283268   ENSP00000418804  

FEZF2 Human Recombinant Protein Products:

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LSBio Antibodies in human, mouse, rat for FEZF2

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
ZNF: Zinc fingers, C2H2-type

3 InterPro protein domains:
 IPR015880 Znf_C2H2-like
 IPR013087 Znf_C2H2/integrase_DNA-bd
 IPR007087 Znf_C2H2

Graphical View of Domain Structure for InterPro Entry Q8TBJ5

ProtoNet protein and cluster: Q8TBJ5

UniProtKB/Swiss-Prot: FEZF2_HUMAN, Q8TBJ5
Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
Similarity: Contains 6 C2H2-type zinc fingers


Find genes that share domains with FEZF2           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: FEZF2_HUMAN, Q8TBJ5
Function: Transcription repressor. Required for the specification of corticospinal motor neurons and other
subcerebral projection neurons. May play a role in layer and neuronal subtype-specific patterning of subcortical
projections and axonal fasciculation. Controls the development of dendritic arborization and spines of large
layer V pyramidal neurons. May be involved in innate immunity (By similarity)

     Gene Ontology (GO): 2 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding IEA--
GO:0046872metal ion binding IEA--
     
Find genes that share ontologies with FEZF2           About GenesLikeMe


Phenotypes:
     8 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Fezf2):
 behavior/neurological  cellular  craniofacial  growth/size/body  mortality/aging 
 nervous system  respiratory system  taste/olfaction 

Find genes that share phenotypes with FEZF2           About GenesLikeMe

Animal Models:
     MGI mouse knock-out Fezf2tm1Hibi for FEZF2

   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FEZF2
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FEZF2

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FEZF2
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FEZF2

miRNA
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3 qRT-PCR Assays for microRNAs that regulate FEZF2:
hsa-let-7g* hsa-miR-3121-3p hsa-let-7a-2*
SwitchGear 3'UTR luciferase reporter plasmidFEZF2 3' UTR sequence
Inhib. RNA
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Predesigned siRNA for gene silencing in human, mouse, rat FEZF2

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GenScript: all cDNA clones in your preferred vector: FEZF2 (NM_018008)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for FEZF2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FEZF2
Addgene plasmids for FEZF2 

Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FEZF2


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
FEZF2_HUMAN, Q8TBJ5: Nucleus (By similarity)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus3

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IEA--

Find genes that share ontologies with FEZF2           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FEZF2
Interactions:

    Search GeneGlobe Interaction Network for FEZF2

Gene Ontology (GO): Selected biological process terms (see all 15):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0000122negative regulation of transcription from RNA polymerase II promoter IEA--
GO:0006351transcription, DNA-templated IEA--
GO:0007411axon guidance IEA--
GO:0007413axonal fasciculation IEA--
GO:0007626locomotory behavior IEA--

Find genes that share ontologies with FEZF2           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for FEZF2



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for FEZF2 gene: 
NM_018008.3  

Unigene Cluster for FEZF2:

FEZ family zinc finger 2
Hs.241523  [show with all ESTs]
Unigene Representative Sequence: NM_018008
3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000486811 ENST00000283268(uc003dli.2) ENST00000475839(uc003dlh.2)

miRNA
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Block miRNA regulation of human, mouse, rat FEZF2 using miScript Target Protectors
3 qRT-PCR Assays for microRNAs that regulate FEZF2:
hsa-let-7g* hsa-miR-3121-3p hsa-let-7a-2*
SwitchGear 3'UTR luciferase reporter plasmidFEZF2 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for FEZF2
Predesigned siRNA for gene silencing in human, mouse, rat FEZF2
Clone
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OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: FEZF2 (NM_018008)
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Addgene plasmids for FEZF2 
Primer
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OriGene qPCR primer pairs and template standards for FEZF2
OriGene qSTAR qPCR primer pairs in human, mouse for FEZF2
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FEZF2
  QuantiTect SYBR Green Assays in human, mouse, rat FEZF2
  QuantiFast Probe-based Assays in human, mouse, rat FEZF2

Additional mRNA sequence: 

AF064845.1 AF332890.1 AK001004.1 AK290464.1 BC022464.1 

4 DOTS entries:

DT.97840041  DT.101976175  DT.100812271  DT.100719005 

Selected AceView cDNA sequences (see all 67):

BM930804 CR599241 BU162164 AK001004 BX100071 AK094634 BM684654 BC041886 
AF332890 BM669347 BM698078 BM699045 AA429887 BM807621 BI561432 AU118280 
AA150100 BX329013 AW072192 AI637719 BG721701 AA152230 AL530810 BI913433 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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FEZF2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: TAAATCCTCC
FEZF2 Expression
About this image


FEZF2 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 5) fully expand
 
 Neural Tube (Nervous System)    fully expand to see all 2 entries
         Diencephalic Ventricular Zone
         Floor plate-like cells
 
 Brain (Nervous System)
         Cerebellum
 
 Neurons
         Type1 Off Cone Bipolar Cells Inner Nuclear Layer
 
 Neural Ectoderm (Nervous System)
         Neural ectoderm cells
 
 Eye (Sensory Organs)
         Type1 Off Cone Bipolar Cells Inner Nuclear Layer
FEZF2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

FEZF2 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.241523
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QuantiFast Probe-based Assays in human, mouse, rat FEZF2
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FEZF2

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for FEZF2 gene from Selected species (see all 15)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Fezf21 , 5 Fez family zinc finger 21, 5 90.75(n)1
96.48(a)1
  14 (6.36 cM)5
547131  NM_080433.31  NP_536681.21 
 123418925 
chicken
(Gallus gallus)
Aves FEZF21 FEZ family zinc finger 2 78.53(n)
80.7(a)
  416074  XM_414411.3  XP_414411.2 
lizard
(Anolis carolinensis)
Reptilia FEZF26
FEZ family zinc finger 2
56(a)
1 ↔ 1
GL343210.1(3187650-3200155)
African clawed frog
(Xenopus laevis)
Amphibia BJ078956.12   -- 80.74(n)    BJ078956.1 
zebrafish
(Danio rerio)
Actinopterygii fezl2 forebrain embryonic zinc-finger like 76.8(n)   60634  AB041824.1 
fruit fly
(Drosophila melanogaster)
Insecta erm6
earmuff
32(a)
1 → many
2L(1950239-1970514)
worm
(Caenorhabditis elegans)
Secernentea fezf-16
Protein Y38H8A.5 (Y38H8A.5) mRNA, complete cds
66(a)
1 → many
IV(13466139-13469402) WBGene00012639


ENSEMBL Gene Tree for FEZF2 (if available)
TreeFam Gene Tree for FEZF2 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for FEZF2 gene
GFI12  GFI1B2  ZNF82  FEZF12  
Selected SIMAP similar genes for FEZF2 using alignment to 1 protein entry:     FEZF2_HUMAN(see all similar genes):
ZNF    FEZF1    ZNF430    ZNF78L1    ZNF260    GFI1B
ZNF331    ZNF664    DKFZp686M04222    ZNF72    ZNF85    GFI1
ZNF323    ZNF585B    ZNF600    ZNF501    ZNF589    ZNF80

Find genes that share paralogs with FEZF2           About GenesLikeMe



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for FEZF2 (see all 134)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 3 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1137365061,2
C--62354949(+) AGAAGC/TTCTCC 1 -- ds50011Minor allele frequency- T:0.50WA 2
rs562533061,2
C--62354964(+) GGGTAG/AGGCGT 1 -- ds50014Minor allele frequency- A:0.09WA NA EA 360
rs1813704691,2
--62355252(+) GTGCAC/TTTAGG 1 -- ds50010--------
rs32150301,2
C--62355666(+) TTTTT-/TCTTTT 1 -- ut31 trp30--------
rs1864860691,2
C--62355749(+) CAAGGC/TAGTAG 1 -- ut310--------
rs2014562851,2
--62355797(+) GAGGGA/GGCAGC 2 A syn10--------
rs1904264531,2
C--62355821(+) TCGTGG/TAGTTT 2 L syn10--------
rs762773721,2
C--62355856(+) GTTTCC/TGCAAA 2 R G mis10--------
rs2007640571,2
--62355935(+) TTGTAA/GACCTG 2 V syn10--------
rs1829283341,2
--62356105(+) AGGTGC/TCTGCT 1 -- int10--------

HapMap Linkage Disequilibrium report for FEZF2 (62355347 - 62359999 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for FEZF2: --
Human Gene Mutation Database (HGMD): FEZF2
Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing FEZF2
DNA2.0 Custom Variant and Variant Library Synthesis for FEZF2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 607414    OMIM disorders: --

3 diseases for FEZF2:    
About MalaCards
uterine inversion    breast metaplastic carcinoma    lymph node tuberculosis

3 diseases from the University of Copenhagen DISEASES database for FEZF2:
Uterine inversion     Breast metaplastic carcinoma     Lymph node tuberculosis

Find genes that share disorders with FEZF2           About GenesLikeMe


Export disorders for FEZF2 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for FEZF2 gene, integrated from 10 sources (see all 14):
(articles sorted by number of sources associating them with FEZF2)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  2. Directed differentiation of human embryonic stem cells into corticofugal neurons uncovers heterogeneous Fezf2-expressing subpopulations. (PubMed id 23826257)1 Kmet M....Chen B. (PLoS ONE 2013)
  3. FEZF2, a novel 3p14 tumor suppressor gene, represses oncogene EZH2 and MDM2 expression and is frequently methylated in nasopharyngeal carcinoma. (PubMed id 23677067)1 Shu X.S....Tao Q. (Carcinogenesis 2013)
  4. Resequencing of 29 candidate genes in patients with familial and sporadic amyotrophic lateral sclerosis. (PubMed id 21220648)2 Daoud H....Rouleau G.A. (Arch. Neurol. 2011)
  5. Genomic selection identifies vertebrate transcription factor Fezf2 binding sites and target genes. (PubMed id 21471212)1 Chen L....Guo S. (J. Biol. Chem. 2011)
  6. Area dependent expression of ZNF312 in human fetal cerebral cortex. (PubMed id 20570630)1 Zhu H....Chen J. (Neurosci. Res. 2010)
  7. Genome-scale RNAi screen for host factors required for HIV replication. (PubMed id 18976975)1 Zhou H....Espeseth A.S. (amp 2008)
  8. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
  9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 55079 HGNC: 13506 AceView: ZNF312 Ensembl:ENSG00000153266 euGenes: HUgn55079
ECgene: FEZF2 H-InvDB: FEZF2

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for FEZF2 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for FEZF2 gene:
Search GeneIP for patents involving FEZF2

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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