Aliases for FERMT3 Gene
Aliases for FERMT3 Gene
External Ids for FERMT3 Gene
- HGNC: 23151
- Entrez Gene: 83706
- Ensembl: ENSG00000149781
- OMIM: 607901
- UniProtKB: Q86UX7
Previous GeneCards Identifiers for FERMT3 Gene
- GC11P063731
- GC11P063975
- GC11P060302
Summaries for FERMT3 Gene
-
Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2010]
GeneCards Summary for FERMT3 Gene
FERMT3 (Fermitin Family Member 3) is a Protein Coding gene. Diseases associated with FERMT3 include Leukocyte Adhesion Deficiency, Type Iii and Leukocyte Adhesion Deficiency. Among its related pathways are Adhesion and Response to elevated platelet cytosolic Ca2+. GO annotations related to this gene include integrin binding. An important paralog of this gene is FERMT1.
UniProtKB/Swiss-Prot for FERMT3 Gene
-
Plays a central role in cell adhesion in hematopoietic cells (PubMed:19234463, PubMed:26359933). Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3) (By similarity). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells (PubMed:19234460). Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (By similarity).
-
Isoform 2 may act as a repressor of NF-kappa-B and apoptosis.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FERMT3 Gene
Genomics for FERMT3 Gene
Regulatory Elements for FERMT3 Gene
Enhancers for FERMT3 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FERMT3 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the FERMT3 gene promoter:
Regulatory Element Products
Genomic Location for FERMT3 Gene
- Chromosome:
- 11
- Start:
- 64,206,655 bp from pter
- End:
- 64,223,891 bp from pter
- Size:
- 17,237 bases
- Orientation:
- Plus strand
Genomic View for FERMT3 Gene
Genes around FERMT3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q13.1 by Ensembl
- 11q13.1 by Entrez Gene
- 11q13.1 by HGNC
FERMT3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FERMT3 Gene
Proteins for FERMT3 Gene
-
Protein details for FERMT3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q86UX7-URP2_HUMAN
- Recommended name:
- Fermitin family homolog 3
- Protein Accession:
- Q86UX7
- Q8IUA1
- Q8N207
- Q9BT48
Protein attributes for FERMT3 Gene
- Size:
- 667 amino acids
- Molecular mass:
- 75953 Da
- Quaternary structure:
-
- Interacts with ITGB1, ITGB2 and ITGB3 (via cytoplasmic tails).
Protein Expression for FERMT3 Gene
Post-translational modifications for FERMT3 Gene
Other Protein References for FERMT3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for FERMT3
- R&D Systems Antibodies for FERMT3 (FERMT3)
- Cell Signaling Technology (CST) Antibodies for FERMT3 (kindlin-3)
- Novus Biologicals Antibodies for FERMT3
- Invitrogen Antibodies for FERMT3
- antibodies-online Antibodies for FERMT3: See all 56
- GeneTex FERMT3 antibody for FERMT3
-
Custom Antibody ServicesProSci Antibodies for FERMT3
Protein Products
-
OriGene Purified Proteins for FERMT3
- Search Origene for MassSpec and Protein Over-expression Lysates for FERMT3
- Origene Custom Protein Services for FERMT3
- antibodies-online Proteins for FERMT3: See all 5
- Search antibodies-online for peptides
- Search GeneTex for Proteins for FERMT3
Assay Products
- antibodies-online Kits for FERMT3: See all 3
No data available for DME Specific Peptides for FERMT3 Gene
Domains & Families for FERMT3 Gene
Gene Families for FERMT3 Gene
Protein Domains for FERMT3 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for FERMT3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q86UX7UniProtKB/Swiss-Prot:
URP2_HUMAN :- The FERM domain is not correctly detected by PROSITE or Pfam techniques because it contains the insertion of a PH domain.
- Belongs to the kindlin family.
- Domain:
-
- The FERM domain is not correctly detected by PROSITE or Pfam techniques because it contains the insertion of a PH domain.
- Family:
-
- Belongs to the kindlin family.
Function for FERMT3 Gene
Molecular function for FERMT3 Gene
- UniProtKB/Swiss-Prot Function:
- Plays a central role in cell adhesion in hematopoietic cells (PubMed:19234463, PubMed:26359933). Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3) (By similarity). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells (PubMed:19234460). Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (By similarity).
- UniProtKB/Swiss-Prot Function:
- Isoform 2 may act as a repressor of NF-kappa-B and apoptosis.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005178 | integrin binding | IEA,ISS | -- |
Phenotypes for FERMT3 Gene
- MGI mutant phenotypes for FERMT3:
- inferred from 5 alleles
- GenomeRNAi human phenotypes for FERMT3:
Animal Models for FERMT3 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for FERMT3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FERMT3 gene
- Search ViGene Biosciences for FERMT3
CRISPR Products
-
OriGene CRISPR knockouts for FERMT3
-
Santa Cruz Biotechnology (SCBT) CRISPR for FERMT3
- GenScript: Design CRISPR guide RNA sequences for FERMT3
miRNA Products
- Search ViGene Biosciences for FERMT3
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for FERMT3
- Browse OriGene Inhibitory RNA Products For FERMT3
-
ViGene Biosciences ready-to-package AAV shRNAs for FERMT3 gene
Clone Products
- Sino Biological Human cDNA Clone for FERMT3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
Horizon Cell Lines for FERMT3
-
ViGene Biosciences adenoviral particle packaged cDNA for FERMT3 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FERMT3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FERMT3 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , miRNA , Transcription Factor Targets and HOMER Transcription for FERMT3 Gene
Localization for FERMT3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for FERMT3 Gene
- Cell projection, podosome. Note=Present in the F-actin surrounding ring structure of podosomes, which are specialized adhesion structures of hematopoietic cells. {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| cytoskeleton | 4 |
| cytosol | 3 |
| plasma membrane | 2 |
| nucleus | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002102 | podosome | ISS | -- |
| GO:0005576 | extracellular region | TAS | -- |
| GO:0016020 | membrane | IDA | 19946888 |
| GO:0030054 | cell junction | IEA | -- |
| GO:0031093 | platelet alpha granule lumen | TAS | -- |
Pathways & Interactions for FERMT3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Response to elevated platelet cytosolic Ca2+ |
.44
|
|
| 2 | Platelet activation | ||
| 3 | Adhesion |
-
|
|
Pathways by source for FERMT3 Gene
1 Cell Signaling Technology pathway for FERMT3 Gene
4 Reactome pathways for FERMT3 Gene
1 KEGG pathway for FERMT3 Gene
Interacting Proteins for FERMT3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002576 | platelet degranulation | TAS | -- |
| GO:0007155 | cell adhesion | IEA | -- |
| GO:0007159 | leukocyte cell-cell adhesion | IMP | 19234460 |
| GO:0007229 | integrin-mediated signaling pathway | IMP | 19234460 |
| GO:0030335 | positive regulation of cell migration | IDA | 19234463 |
No data available for SIGNOR curated interactions for FERMT3 Gene
Transcripts for FERMT3 Gene
mRNA/cDNA for FERMT3 Gene
- (6) REFSEQ mRNAs :
- (6) Additional mRNA sequences :
- (151) Selected AceView cDNA sequences:
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FERMT3 Gene
CRISPR Products
-
OriGene CRISPR knockouts for FERMT3
-
Santa Cruz Biotechnology (SCBT) CRISPR for FERMT3
- GenScript: Design CRISPR guide RNA sequences for FERMT3
miRNA Products
- Search ViGene Biosciences for FERMT3
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for FERMT3
- Browse OriGene Inhibitory RNA Products For FERMT3
-
ViGene Biosciences ready-to-package AAV shRNAs for FERMT3 gene
Clone Products
- Sino Biological Human cDNA Clone for FERMT3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||||||||||||
| SP7: |
Expression for FERMT3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Yolk Sac (Extraembryonic Tissues)
- Definitive Hematopoietic Stem Cells Definitive Yolk Sac
-
Blood (Cardiovascular System)
- Definitive Hematopoietic Stem Cells Definitive Yolk Sac
- Bone (Muscoskeletal System)
-
Tonsil (Hematopoietic System)
-
Dermis (Integumentary System)
mRNA differential expression in normal tissues according to GTEx for FERMT3 Gene
This gene is overexpressed in Whole Blood (x24.0) and Spleen (x4.7).
This gene is overexpressed in Platelet (29.6), Peripheral blood mononuclear cells (13.1), and Lymph node (7.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for FERMT3 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of FERMT3 Gene:
FERMT3SOURCE GeneReport for Unigene cluster for FERMT3 Gene:
Hs.180535mRNA Expression by UniProt/SwissProt for FERMT3 Gene:
Q86UX7-URP2_HUMAN
Tissue specificity:
Highly expressed in lymph node. Expressed in thymus, spleen and leukocytes. Weakly expressed in placenta, small intestine, stomach, testis and lung. Overexpressed in B-cell malignancies.
Evidence on tissue expression from TISSUES for FERMT3 Gene
- Blood(4.6)
- Lung(4.4)
- Skin(2.9)
- Bone marrow(2.3)
- Heart(2.2)
- Lymph node(2.1)
Phenotype-based relationships between genes and organs from Gene ORGANizer for FERMT3 Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- cardiovascular
- digestive
- immune
- integumentary
- lymphatic
Organs:
Head and neck:
- face
- head
- nose
Abdomen:
- liver
- spleen
General:
- blood
- blood vessel
- coagulation system
- red blood cell
- skin
- white blood cell
Primer Products
-
OriGene qPCR primer pairs and template standards for FERMT3
-
OriGene qPCR primer pairs for FERMT3
Orthologs for FERMT3 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FERMT3 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | FERMT3 35 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | FERMT3 34 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | FERMT3 35 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Fermt3 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Fermt3 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
ManyToMany | |
| lizard (Anolis carolinensis) |
Reptilia | FERMT3 35 |
|
OneToOne | |
| African clawed frog (Xenopus laevis) |
Amphibia | MGC69069 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | fermt3b 34 35 |
|
||
| FERMT3 (2 of 2) 35 |
|
OneToMany | |||
| zgc64101 34 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.9754 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | Fit1 35 |
|
ManyToMany | |
| Fit2 35 |
|
ManyToMany | |||
| worm (Caenorhabditis elegans) |
Secernentea | unc-112 35 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToMany |
- Species where no ortholog for FERMT3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Paralogs for FERMT3 Gene
(3) SIMAP similar genes for FERMT3 Gene using alignment to 4 proteins:
Pseudogenes.org Pseudogenes for FERMT3 Gene
Variants for FERMT3 Gene
| SNP ID | Clin | Chr 11 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| VAR_074597 | Leukocyte adhesion deficiency 3 (LAD3) [MIM:612840] | ||||
| rs121918295 | Pathogenic | 64,220,649(+) | TCCAG(C/T)GAAAG | reference, stop-gained | |
| rs121918296 | Pathogenic | 64,207,412(+) | TCATG(A/G)GAGCT | upstream-variant-2KB, reference, stop-gained | |
| rs121918297 | Pathogenic | 64,223,094(+) | ACAAC(C/T)GACTG | reference, stop-gained | |
| rs121918298 | Pathogenic | 64,211,648(+) | AGGTG(A/G)CTGGA | reference, stop-gained |
Residual Variation Intolerance Score:
93.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.51;
43.89% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FERMT3 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FERMT3 Gene
Disorders for FERMT3 Gene
(4) MalaCards diseases for FERMT3 Gene - From: OMIM, ClinVar, GeneTests, Orphanet, DISEASES, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| leukocyte adhesion deficiency, type iii |
|
|
| leukocyte adhesion deficiency |
|
|
| kindler syndrome |
|
|
| phagocyte bactericidal dysfunction |
|
|
Search FERMT3 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
URP2_HUMAN- Leukocyte adhesion deficiency 3 (LAD3) [MIM:612840]: A disorder characterized by recurrent bacterial infections without pus formation, leukocytosis and major bleeding disorders. {ECO:0000269 PubMed:18779414, ECO:0000269 PubMed:19064721, ECO:0000269 PubMed:19234460, ECO:0000269 PubMed:19234463, ECO:0000269 PubMed:19617577, ECO:0000269 PubMed:26359933}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Relevant External Links for FERMT3
No data available for Genatlas for FERMT3 Gene
Publications for FERMT3 Gene
- LAD-1/variant syndrome is caused by mutations in FERMT3. (PMID: 19064721) Kuijpers T.W. … Baas F. (Blood 2009) 3 4 22 64
- A point mutation in KINDLIN3 ablates activation of three integrin subfamilies in humans. (PMID: 19234460) Malinin N.L. … Byzova T.V. (Nat. Med. 2009) 3 4 22 64
- Loss of Kindlin-3 in LAD-III eliminates LFA-1 but not VLA-4 adhesiveness developed under shear flow conditions. (PMID: 19617577) Manevich-Mendelson E. … Alon R. (Blood 2009) 3 4 22 64
- Kindlin-3: a new gene involved in the pathogenesis of LAD-III. (PMID: 18779414) Mory A. … Alon R. (Blood 2008) 3 4 22 64
- URP1: a member of a novel family of PH and FERM domain-containing membrane-associated proteins is significantly over-expressed in lung and colon carcinomas. (PMID: 12697302) Weinstein E.J. … Mazzarella R. (Biochim. Biophys. Acta 2003) 3 4 22 64
Products for FERMT3 Gene
- R&D Systems Antibodies for FERMT3 (FERMT3)
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
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- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
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- Custom Antibody ServicesOriGene Antibodies for FERMT3
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for FERMT3
- Search Origene for MassSpec and Protein Over-expression Lysates for FERMT3
- Origene Custom Protein Services for FERMT3
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for FERMT3
- Browse OriGene Inhibitory RNA Products For FERMT3
- OriGene qPCR primer pairs and template standards for FERMT3
- OriGene qPCR primer pairs for FERMT3
- OriGene CRISPR knockouts for FERMT3
- OriGene ORF clones in human for FERMT3
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- GenScript: Next-day shipping cDNA ORF clone for FERMT3 in any vector
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- GenScript: Design CRISPR guide RNA sequences for FERMT3
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- CloneReady with Over 120,000 Genes
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- GenScript Custom Peptide Services for FERMT3
- Cell Signaling Technology (CST) Antibodies for FERMT3 (kindlin-3)
- Search for Antibodies & Assays
- Sino Biological Human cDNA Clone for FERMT3
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- Sino Biological Antibodies
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- Sino Biological Cell Lysates
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for FERMT3
- Novus Biologicals proteins and lysates for FERMT3
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- antibodies-online Antibodies for FERMT3: See all 56
- antibodies-online Kits for FERMT3: See all 3
- antibodies-online Proteins for FERMT3: See all 5
- Search antibodies-online for peptides
- GeneTex FERMT3 antibody for FERMT3
- Search GeneTex for Proteins for FERMT3
- ViGene Biosciences adenoviral particle packaged cDNA for FERMT3 gene
- ViGene Biosciences lentiviral particle packaged cDNA for FERMT3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for FERMT3 gene
- Search ViGene Biosciences for FERMT3
- Custom Antibody ServicesProSci Antibodies for FERMT3
- Search for FERMT3 Proteins at ProSci
- Horizon Cell Lines for FERMT3
- Cyagen custom Knockout/knockin (KOKI) mouse models for FERMT3
- VectorBuilder custom plasmid, inducible vectors for FERMT3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FERMT3
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FERMT3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
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