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Aliases for FER1L4 Gene

Aliases for FER1L4 Gene

  • Fer-1 Like Family Member 4, Pseudogene 2 3
  • Fer-1 Like Family Member 4, Pseudogene (Functional) 2 3
  • Fer-1-Like Family Member 4, Pseudogene (Functional) 3 5
  • C20orf124 3 4
  • Fer-1-Like 4 (C. Elegans), Pseudogene (Functional) 2
  • Fer-1-Like 4, Pseudogene (Functional) 3
  • Fer-1-Like 4 (C. Elegans) 2

External Ids for FER1L4 Gene

Previous HGNC Symbols for FER1L4 Gene

  • C20orf124

Previous GeneCards Identifiers for FER1L4 Gene

  • GC20M033904
  • GC20M034814
  • GC20M034861
  • GC20M034862
  • GC20M033609
  • GC20M034146
  • GC20M030924

Summaries for FER1L4 Gene

GeneCards Summary for FER1L4 Gene

FER1L4 (Fer-1 Like Family Member 4, Pseudogene) is a Pseudogene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FER1L4 Gene

Genomics for FER1L4 Gene

Regulatory Elements for FER1L4 Gene

Enhancers for FER1L4 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around FER1L4 on UCSC Golden Path with GeneCards custom track

Genomic Location for FER1L4 Gene

Chromosome:
20
Start:
35,558,737 bp from pter
End:
35,607,562 bp from pter
Size:
48,826 bases
Orientation:
Minus strand

Genomic View for FER1L4 Gene

Genes around FER1L4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FER1L4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FER1L4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FER1L4 Gene

Proteins for FER1L4 Gene

  • Protein details for FER1L4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A9Z1Z3-FR1L4_HUMAN
    Recommended name:
    Fer-1-like protein 4
    Protein Accession:
    A9Z1Z3
    Secondary Accessions:
    • Q9GZQ9
    • Q9H646
    • Q9H8L7

    Protein attributes for FER1L4 Gene

    Size:
    1794 amino acids
    Molecular mass:
    200980 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB14597.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for FER1L4 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FER1L4 Gene

Proteomics data for FER1L4 Gene at MOPED

Post-translational modifications for FER1L4 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FER1L4 Gene

Domains & Families for FER1L4 Gene

Protein Domains for FER1L4 Gene

Suggested Antigen Peptide Sequences for FER1L4 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A9Z1Z3

UniProtKB/Swiss-Prot:

FR1L4_HUMAN :
  • Contains 5 C2 domains.
  • Belongs to the ferlin family.
Domain:
  • Contains 5 C2 domains.
Family:
  • Belongs to the ferlin family.
genes like me logo Genes that share domains with FER1L4: view

Function for FER1L4 Gene

Phenotypes for FER1L4 Gene

GenomeRNAi human phenotypes for FER1L4:
genes like me logo Genes that share phenotypes with FER1L4: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FER1L4 Gene

Localization for FER1L4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for FER1L4 Gene

Membrane; Single-pass membrane protein.

No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FER1L4 Gene

Pathways & Interactions for FER1L4 Gene

SuperPathways for FER1L4 Gene

No Data Available

Interacting Proteins for FER1L4 Gene

Gene Ontology (GO) - Biological Process for FER1L4 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FER1L4 Gene

Drugs & Compounds for FER1L4 Gene

No Compound Related Data Available

Transcripts for FER1L4 Gene

Unigene Clusters for FER1L4 Gene

Fer-1-like 4 (C. elegans) pseudogene:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FER1L4 Gene

No ASD Table

Relevant External Links for FER1L4 Gene

GeneLoc Exon Structure for
FER1L4
ECgene alternative splicing isoforms for
FER1L4

Expression for FER1L4 Gene

mRNA expression in normal human tissues for FER1L4 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FER1L4 Gene

This gene is overexpressed in Bladder (x12.0) and Stomach (x9.2).

Protein differential expression in normal tissues from HIPED for FER1L4 Gene

This gene is overexpressed in Monocytes (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FER1L4 Gene



SOURCE GeneReport for Unigene cluster for FER1L4 Gene Hs.72222

genes like me logo Genes that share expression patterns with FER1L4: view

Protein tissue co-expression partners for FER1L4 Gene

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for FER1L4 Gene

Orthologs for FER1L4 Gene

Evolution for FER1L4 Gene

ENSEMBL:
Gene Tree for FER1L4 (if available)
TreeFam:
Gene Tree for FER1L4 (if available)

No data available for Orthologs for FER1L4 Gene

Paralogs for FER1L4 Gene

(3) SIMAP similar genes for FER1L4 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with FER1L4: view

No data available for Paralogs for FER1L4 Gene

Variants for FER1L4 Gene

Sequence variations from dbSNP and Humsavar for FER1L4 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs1557202 - 35,576,500(+) TTCCT(C/T)CAGGG nc-transcript-variant
rs11698021 - 35,576,487(+) AGTGG(C/T)TAAAT nc-transcript-variant
rs2277862 - 35,564,866(-) TCGCC(A/G)TATTT nc-transcript-variant
rs188878 -- 35,568,093(+) ctctg(A/C)ctcca intron-variant
rs224423 -- 35,560,079(+) agggc(C/T)ggagg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FER1L4 Gene

Variant ID Type Subtype PubMed ID
nsv517785 CNV Loss 19592680
nsv526796 CNV Loss 19592680
nsv178794 CNV Loss 16902084
nsv526188 CNV Gain 19592680
esv2664066 CNV Deletion 23128226
esv2722366 CNV Deletion 23290073
dgv698n67 CNV Loss 20364138

Relevant External Links for FER1L4 Gene

HapMap Linkage Disequilibrium report
FER1L4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for FER1L4 Gene

Disorders for FER1L4 Gene

Relevant External Links for FER1L4

Genetic Association Database (GAD)
FER1L4
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FER1L4

No disorders were found for FER1L4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FER1L4 Gene

Publications for FER1L4 Gene

  1. Clinical significance of the low expression of FER1L4 in gastric cancer patients. (PMID: 24961353) Liu Z. … Guo J. (Tumour Biol. 2014) 2 3 67
  2. Long non-coding RNA expression profile in human gastric cancer and its clinical significances. (PMID: 24063685) Song H. … Guo J. (J Transl Med 2013) 2 3
  3. Long noncoding RNA FER1L4 suppresses cancer cell growth by acting as a competing endogenous RNA and regulating PTEN expression. (PMID: 26306906) Xia T. … Guo J. (Sci Rep 2015) 3
  4. Long non-coding RNA Fer-1-like protein 4 suppresses oncogenesis and exhibits prognostic value by associating with miR-106a-5p in colon cancer. (PMID: 26224446) Yue B. … Yan D. (Cancer Sci. 2015) 3
  5. Discovery and refinement of loci associated with lipid levels. (PMID: 24097068) . … Abecasis G.R. (Nat. Genet. 2013) 3

Products for FER1L4 Gene

Sources for FER1L4 Gene

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